{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Central+Nervous+System+Anomalies&page=35", "query": { "condition": "Central Nervous System Anomalies", "page": 35 }, "page_size": 10 }, "pagination": { "page": 35, "page_size": 10, "total_count": 1709, "total_pages": 171, "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Central+Nervous+System+Anomalies&page=36&page_size=10", "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Central+Nervous+System+Anomalies&page=34&page_size=10" }, "source": "remote", "last_synced_at": "2026-10-16T11:05:24.879Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT06560736", "title": "Development of Novel Psychological Assessment Tools and Anxiety Intervention for Phenylketonuria", "overall_status": "RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Phenylketonurias" ], "interventions": [ { "name": "Show Me FIRST coping skills intervention", "type": "BEHAVIORAL" } ], "intervention_types": [ "BEHAVIORAL" ], "sponsor": "University of Missouri-Columbia", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "10 Years", "maximum_age": "17 Years", "sex": "ALL", "summary": "10 Years to 17 Years" }, "enrollment_count": 30, "start_date": "2024-10-01", "completion_date": "2026-08-31", "has_results": false, "last_update_posted_date": "2025-12-23", "last_synced_at": "2026-10-16T11:05:24.879Z", "location_count": 1, "location_summary": "Columbia, Missouri", "locations": [ { "city": "Columbia", "state": "Missouri" } ], "official_url": "https://clinicaltrials.gov/study/NCT06560736" }, { "nct_id": "NCT03952234", "title": "L-Citrulline Dose Finding Safety Study in MELAS", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "MELAS Syndrome" ], "interventions": [ { "name": "L-Citrulline", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Baylor College of Medicine", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "65 Years", "sex": "ALL", "summary": "18 Years to 65 Years" }, "enrollment_count": 10, "start_date": "2021-04-22", "completion_date": "2024-06-01", "has_results": false, "last_update_posted_date": "2024-06-26", "last_synced_at": "2026-10-16T11:05:24.879Z", "location_count": 1, "location_summary": "Houston, Texas", "locations": [ { "city": "Houston", "state": "Texas" } ], "official_url": "https://clinicaltrials.gov/study/NCT03952234" }, { "nct_id": "NCT02791230", "title": "Long-term Safety of Tafamidis in Subjects With Transthyretin Cardiomyopathy", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Transthyretin (TTR) Amyloid Cardiomyopathy" ], "interventions": [ { "name": "Tafamidis", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Pfizer", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 1733, "start_date": "2016-06-13", "completion_date": "2023-11-02", "has_results": true, "last_update_posted_date": "2025-02-03", "last_synced_at": "2026-10-16T11:05:24.879Z", "location_count": 41, "location_summary": "Birmingham, Alabama • Beverly Hills, California • La Jolla, California + 20 more", "locations": [ { "city": "Birmingham", "state": "Alabama" }, { "city": "Birmingham", "state": "Alabama" }, { "city": "Birmingham", "state": "Alabama" }, { "city": "Beverly Hills", "state": "California" }, { "city": "Beverly Hills", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT02791230" }, { "nct_id": "NCT00551200", "title": "Dose-Escalation Safety Study of HPN-100 to Treat Urea Cycle Disorders", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Urea Cycle Disorders" ], "interventions": [ { "name": "HPN-100", "type": "DRUG" }, { "name": "BUPHENYL®", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Amgen", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 14, "start_date": "2007-10", "completion_date": "2008-12", "has_results": true, "last_update_posted_date": "2024-07-10", "last_synced_at": "2026-10-16T11:05:24.879Z", "location_count": 2, "location_summary": "Minneapolis, Minnesota • Houston, Texas", "locations": [ { "city": "Minneapolis", "state": "Minnesota" }, { "city": "Houston", "state": "Texas" } ], "official_url": "https://clinicaltrials.gov/study/NCT00551200" }, { "nct_id": "NCT07190300", "title": "TulmiSTAR-02: A Phase I/II Open-label Study of Tulmimetostat in Combination With Darolutamide vs. Darolutamide, and Tulmimetostat With Abiraterone in Patients With Metastatic Hormone-sensitive Prostate Cancer (mHSPC)", "overall_status": "RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1", "PHASE2" ], "conditions": [ "Metastatic Hormone-Sensitive Prostate Cancer (mHSPC)" ], "interventions": [ { "name": "Tulmimetostat", "type": "DRUG" }, { "name": "Darolutamide", "type": "DRUG" }, { "name": "Abiraterone", "type": "DRUG" }, { "name": "Prednisone/Prednisolone", "type": "DRUG" }, { "name": "Androgen Deprivation Therapy (ADT)", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Novartis Pharmaceuticals", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "MALE", "summary": "18 Years and older · Male only" }, "enrollment_count": 181, "start_date": "2026-01-13", "completion_date": "2032-08-02", "has_results": false, "last_update_posted_date": "2026-09-29", "last_synced_at": "2026-10-16T11:05:24.879Z", "location_count": 8, "location_summary": "Birmingham, Alabama • Iowa City, Iowa • Westwood, Kansas + 5 more", "locations": [ { "city": "Birmingham", "state": "Alabama" }, { "city": "Iowa City", "state": "Iowa" }, { "city": "Westwood", "state": "Kansas" }, { "city": "Wichita", "state": "Kansas" }, { "city": "Durham", "state": "North Carolina" } ], "official_url": "https://clinicaltrials.gov/study/NCT07190300" }, { "nct_id": "NCT05345171", "title": "Clinical Study of DTX301 AAV-Mediated Gene Transfer for Ornithine Transcarbamylase (OTC) Deficiency", "overall_status": "ACTIVE_NOT_RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "OTC Deficiency" ], "interventions": [ { "name": "DTX301", "type": "GENETIC" }, { "name": "Placebo", "type": "OTHER" }, { "name": "Oral Corticosteroids", "type": "DRUG" }, { "name": "Placebo for oral corticosteroids", "type": "DRUG" }, { "name": "Sodium Acetate", "type": "DRUG" } ], "intervention_types": [ "GENETIC", "OTHER", "DRUG" ], "sponsor": "Ultragenyx Pharmaceutical Inc", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "12 Years", "maximum_age": null, "sex": "ALL", "summary": "12 Years and older" }, "enrollment_count": 37, "start_date": "2022-10-18", "completion_date": "2031-03", "has_results": false, "last_update_posted_date": "2026-09-09", "last_synced_at": "2026-10-16T11:05:24.879Z", "location_count": 4, "location_summary": "Los Angeles, California • Aurora, Colorado • Chicago, Illinois + 1 more", "locations": [ { "city": "Los Angeles", "state": "California" }, { "city": "Aurora", "state": "Colorado" }, { "city": "Chicago", "state": "Illinois" }, { "city": "Cleveland", "state": "Ohio" } ], "official_url": "https://clinicaltrials.gov/study/NCT05345171" }, { "nct_id": "NCT01931644", "title": "At-Home Research Study for Patients With Autoimmune, Inflammatory, Genetic, Hematological, Infectious, Neurological, CNS, Oncological, Respiratory, Metabolic Conditions", "overall_status": "COMPLETED", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "All Diagnosed Health Conditions", "ADD/ADHD", "Alopecia Areata", "Ankylosing Spondylitis", "Asthma", "Atopic Dermatitis Eczema", "Beta Thalassemia", "Bipolar Disorder", "Breast Cancer", "Celiac Disease", "Cervical Cancer", "Chronic Inflammatory Demyelinating Polyneuropathy", "Chronic Kidney Diseases", "Chronic Obstructive Pulmonary Disease", "Colon Cancer", "Colorectal Cancer", "Crohn's Disease", "Cystic Fibrosis", "Depression", "Diabetes Mellitus", "Duchenne Muscular Dystrophy", "Endometriosis", "Epilepsy", "Facioscapulohumeral Muscular Dystrophy", "G6PD Deficiency", "General Anxiety Disorder", "Hepatitis B", "Hereditary Hemorrhagic Telangiectasia", "HIV/AIDS", "Human Papilloma Virus", "Huntington's Disease", "Idiopathic Thrombocytopenic Purpura", "Insomnia", "Kidney Cancer", "Leukemia", "Lung Cancer", "Lupus Nephritis", "Lymphoma", "Melanoma", "Multiple Myeloma", "Multiple Sclerosis", "Myositis", "Myotonic Dystrophy", "Ovarian Cancer", "Pancreatic Cancer", "Parkinson's Disease", "Polycystic Kidney Diseases", "Prostate Cancer", "Psoriasis", "Psoriatic Arthritis", "Rosacea", "Scleroderma", "Sickle Cell Anemia", "Sickle Cell Trait", "Sjogren's Syndrome", "Skin Cancer", "Spinal Muscular Atrophy", "Systemic Lupus Erythematosus", "Thrombotic Thrombocytopenic Purpura", "Trisomy 21", "Ulcerative Colitis" ], "interventions": [], "intervention_types": [], "sponsor": "Sanguine Biosciences", "sponsor_class": "INDUSTRY", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "100 Years", "sex": "ALL", "summary": "18 Years to 100 Years" }, "enrollment_count": 17667, "start_date": "2013-07", "completion_date": "2024-04", "has_results": false, "last_update_posted_date": "2024-04-18", "last_synced_at": "2026-10-16T11:05:24.879Z", "location_count": 1, "location_summary": "Los Angeles, California", "locations": [ { "city": "Los Angeles", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT01931644" }, { "nct_id": "NCT01060371", "title": "Natural History Study of and Genetic Modifiers in Spinocerebellar Ataxias", "overall_status": "RECRUITING", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Spinocerebellar Ataxia Type 1", "Spinocerebellar Ataxia Type 2", "Spinocerebellar Ataxia Type 3", "Spinocerebellar Ataxia Type 6", "Spinocerebellar Ataxia Type 7", "Spinocerebellar Ataxia Type 8", "Spinocerebellar Ataxia Type 10", "RFC1 Gene Mutation", "Spinocerebellar Ataxia Type 27b", "Healthy Participants" ], "interventions": [ { "name": "Genetic Testing", "type": "GENETIC" }, { "name": "Blood Collection", "type": "OTHER" }, { "name": "Magnetic Resonance Imaging (MRI) Scan", "type": "OTHER" }, { "name": "Assessments and Questionnaires", "type": "OTHER" }, { "name": "Cerebrospinal Fluid Collection", "type": "OTHER" } ], "intervention_types": [ "GENETIC", "OTHER" ], "sponsor": "Lauren Moore", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "6 Years", "maximum_age": null, "sex": "ALL", "summary": "6 Years and older" }, "enrollment_count": 1400, "start_date": "2010-04", "completion_date": "2030-12", "has_results": false, "last_update_posted_date": "2026-08-03", "last_synced_at": "2026-10-16T11:05:24.879Z", "location_count": 16, "location_summary": "Los Angeles, California • San Francisco, California • Gainesville, Florida + 12 more", "locations": [ { "city": "Los Angeles", "state": "California" }, { "city": "San Francisco", "state": "California" }, { "city": "Gainesville", "state": "Florida" }, { "city": "Tampa", "state": "Florida" }, { "city": "Atlanta", "state": "Georgia" } ], "official_url": "https://clinicaltrials.gov/study/NCT01060371" }, { "nct_id": "NCT02494778", "title": "A Study Evaluating if Pridopidine is Safe, Efficacious, and Tolerable in Patients With Huntington's Disease", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Huntington's Disease" ], "interventions": [ { "name": "Pridopidine", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Prilenia", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "21 Years", "maximum_age": null, "sex": "ALL", "summary": "21 Years and older" }, "enrollment_count": 248, "start_date": "2015-09-24", "completion_date": "2018-01-12", "has_results": true, "last_update_posted_date": "2021-09-17", "last_synced_at": "2026-10-16T11:05:24.879Z", "location_count": 11, "location_summary": "Los Angeles, California • Englewood, Colorado • Washington D.C., District of Columbia + 8 more", "locations": [ { "city": "Los Angeles", "state": "California" }, { "city": "Englewood", "state": "Colorado" }, { "city": "Washington D.C.", "state": "District of Columbia" }, { "city": "Baltimore", "state": "Maryland" }, { "city": "Manhasset", "state": "New York" } ], "official_url": "https://clinicaltrials.gov/study/NCT02494778" }, { "nct_id": "NCT01806051", "title": "A Pilot Study on Diurnal Variation", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Phenylketonuria (PKU)" ], "interventions": [ { "name": "Kuvan", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Dr. Linda Randolph", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "4 Years", "maximum_age": null, "sex": "ALL", "summary": "4 Years and older" }, "enrollment_count": 6, "start_date": "2013-03", "completion_date": "2014-05", "has_results": true, "last_update_posted_date": "2016-04-20", "last_synced_at": "2026-10-16T11:05:24.879Z", "location_count": 1, "location_summary": "Los Angeles, California", "locations": [ { "city": "Los Angeles", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT01806051" } ] }