{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Central+Nervous+System+Depressants", "query": { "condition": "Central Nervous System Depressants" }, "page_size": 10 }, "pagination": { "page": 1, "page_size": 10, "total_count": 24, "total_pages": 3, "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Central+Nervous+System+Depressants&page=2&page_size=10", "previous_page_url": null }, "source": "remote", "last_synced_at": "2026-05-22T09:46:40.680Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT04922593", "title": "Relative Bioavailability of LY03010 Compared to Listed Drug", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "Schizophrenia", "Psychotic Disorders", "Mood Disorders", "Schizophrenia Spectrum", "Mental Disorders", "Antipsychotic Agents", "Tranquilizing Agents", "Central Nervous System Depressants", "Physiological Effects of Drugs", "Psychotropic Drugs", "Neurotransmitter Agents", "Molecular Mechanisms of Pharmacological Action" ], "interventions": [ { "name": "LY03010; paliperidone palmitate", "type": "DRUG" }, { "name": "INVEGA SUSTENNA", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Luye Pharma Group Ltd.", "sponsor_class": "INDUSTRY", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "65 Years", "sex": "ALL", "summary": "18 Years to 65 Years" }, "enrollment_count": 281, "start_date": "2021-01-13", "completion_date": "2022-04-15", "has_results": false, "last_update_posted_date": "2023-04-25", "last_synced_at": "2026-05-22T09:46:40.680Z", "location_count": 9, "location_summary": "Garden Grove, California • Lemon Grove, California • Torrance, California + 6 more", "locations": [ { "city": "Garden Grove", "state": "California" }, { "city": "Lemon Grove", "state": "California" }, { "city": "Torrance", "state": "California" }, { "city": "Miami Lakes", "state": "Florida" }, { "city": "Chicago", "state": "Illinois" } ], "official_url": "https://clinicaltrials.gov/study/NCT04922593" }, { "nct_id": "NCT05405712", "title": "Mobile Peer Support for OUD Recovery", "overall_status": "ACTIVE_NOT_RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Opioid Use Disorder" ], "interventions": [ { "name": "Mobile Phone App", "type": "BEHAVIORAL" } ], "intervention_types": [ "BEHAVIORAL" ], "sponsor": "Brown University", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 1300, "start_date": "2022-05-12", "completion_date": "2027-03", "has_results": false, "last_update_posted_date": "2026-01-29", "last_synced_at": "2026-05-22T09:46:40.680Z", "location_count": 2, "location_summary": "Indianapolis, Indiana • Providence, Rhode Island", "locations": [ { "city": "Indianapolis", "state": "Indiana" }, { "city": "Providence", "state": "Rhode Island" } ], "official_url": "https://clinicaltrials.gov/study/NCT05405712" }, { "nct_id": "NCT05615948", "title": "Oral Aspirin + Ketamine as Adjunct to Oral Antidepressant Therapy for Depression", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Treatment Resistant Depression", "Major Depressive Disorder", "Analgesia", "Ketamine", "Peripheral Nervous System Agents", "Central Nervous System Depressants", "Neurotransmitter Agents", "Anti-Inflammatory Agents", "Physiological Effects of Drugs", "Sensory System Agents", "Analgesics, Non-Narcotic", "Anti-Inflammatory Agents, Non-Steroidal", "Depressive Symptoms" ], "interventions": [ { "name": "VTS-K", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Theresa Jacob, PhD, MPH", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "89 Years", "sex": "ALL", "summary": "18 Years to 89 Years" }, "enrollment_count": 15, "start_date": "2022-12-06", "completion_date": "2024-05-17", "has_results": false, "last_update_posted_date": "2026-04-21", "last_synced_at": "2026-05-22T09:46:40.680Z", "location_count": 1, "location_summary": "Brooklyn, New York", "locations": [ { "city": "Brooklyn", "state": "New York" } ], "official_url": "https://clinicaltrials.gov/study/NCT05615948" }, { "nct_id": "NCT07404306", "title": "Part 1: Dose-Finding of HSK3486 Injection In Nondependent, Recreational Central Nervous System Depressant Users", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "General Anesthesia" ], "interventions": [ { "name": "HSK3486", "type": "DRUG" }, { "name": "propofol", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Haisco-USA Pharmaceuticals, Inc.", "sponsor_class": "INDUSTRY", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "55 Years", "sex": "ALL", "summary": "18 Years to 55 Years" }, "enrollment_count": 43, "start_date": "2022-08-16", "completion_date": "2023-10-03", "has_results": false, "last_update_posted_date": "2026-02-23", "last_synced_at": "2026-05-22T09:46:40.680Z", "location_count": 1, "location_summary": "Salt Lake City, Utah", "locations": [ { "city": "Salt Lake City", "state": "Utah" } ], "official_url": "https://clinicaltrials.gov/study/NCT07404306" }, { "nct_id": "NCT06403852", "title": "Investigating Near-Threshold Perception During Anesthetic Sedation", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Propofol", "Anesthesia", "fMRI" ], "interventions": [ { "name": "Functional Magnetic Resonance Imaging (fMRI) with propofol", "type": "COMBINATION_PRODUCT" } ], "intervention_types": [ "COMBINATION_PRODUCT" ], "sponsor": "University of Michigan", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "40 Years", "sex": "ALL", "summary": "18 Years to 40 Years" }, "enrollment_count": 36, "start_date": "2024-05-10", "completion_date": "2025-10-03", "has_results": false, "last_update_posted_date": "2025-11-13", "last_synced_at": "2026-05-22T09:46:40.680Z", "location_count": 1, "location_summary": "Ann Arbor, Michigan", "locations": [ { "city": "Ann Arbor", "state": "Michigan" } ], "official_url": "https://clinicaltrials.gov/study/NCT06403852" }, { "nct_id": "NCT06021522", "title": "A Study to Evaluate Long-term Safety of Ecopipam Tablets in Children, Adolescents and Adults With Tourette's Disorder", "overall_status": "ACTIVE_NOT_RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Tourette Syndrome" ], "interventions": [ { "name": "Ecopipam", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Emalex Biosciences Inc.", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "6 Years", "maximum_age": null, "sex": "ALL", "summary": "6 Years and older" }, "enrollment_count": 150, "start_date": "2023-08-16", "completion_date": "2027-03", "has_results": false, "last_update_posted_date": "2025-08-13", "last_synced_at": "2026-05-22T09:46:40.680Z", "location_count": 44, "location_summary": "Dothan, Alabama • Little Rock, Arkansas • Anaheim, California + 36 more", "locations": [ { "city": "Dothan", "state": "Alabama" }, { "city": "Little Rock", "state": "Arkansas" }, { "city": "Anaheim", "state": "California" }, { "city": "Bellflower", "state": "California" }, { "city": "Glendale", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT06021522" }, { "nct_id": "NCT05143424", "title": "Evaluation of the Interactions of Cannabidiol (CBD) With Morphine", "overall_status": "UNKNOWN", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "Opioid Use Disorder" ], "interventions": [ { "name": "Morphine Sulfate", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "National Institute on Drug Abuse (NIDA)", "sponsor_class": "NIH", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "55 Years", "sex": "ALL", "summary": "18 Years to 55 Years" }, "enrollment_count": 60, "start_date": "2021-11-04", "completion_date": "2024-12-01", "has_results": false, "last_update_posted_date": "2024-03-27", "last_synced_at": "2026-05-22T09:46:40.680Z", "location_count": 1, "location_summary": "Overland Park, Kansas", "locations": [ { "city": "Overland Park", "state": "Kansas" } ], "official_url": "https://clinicaltrials.gov/study/NCT05143424" }, { "nct_id": "NCT04369950", "title": "Post-cesarean Analgesia With Epidural Morphine Following Epidural 2-chloroprocaine", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Physiological Effect of Drugs", "Morphine", "Analgesics", "Analgesics, Opioid", "Central Nervous System Depressants", "Narcotics" ], "interventions": [ { "name": "2% lidocaine with 1:200,000 epinephrine and epidural morphine", "type": "DRUG" }, { "name": "3% 2-chloroprocaine and epidural morphine", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "The University of Texas Health Science Center, Houston", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "50 Years", "sex": "FEMALE", "summary": "18 Years to 50 Years · Female only" }, "enrollment_count": 44, "start_date": "2020-05-11", "completion_date": "2021-07-11", "has_results": true, "last_update_posted_date": "2022-05-26", "last_synced_at": "2026-05-22T09:46:40.680Z", "location_count": 1, "location_summary": "Houston, Texas", "locations": [ { "city": "Houston", "state": "Texas" } ], "official_url": "https://clinicaltrials.gov/study/NCT04369950" }, { "nct_id": "NCT04015115", "title": "Youth Opioid Recovery Support: Improving Care Systems", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Opioid-Related Disorders" ], "interventions": [ { "name": "Youth Opioid Recovery Support service model", "type": "BEHAVIORAL" } ], "intervention_types": [ "BEHAVIORAL" ], "sponsor": "University of Maryland, Baltimore", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "26 Years", "sex": "ALL", "summary": "18 Years to 26 Years" }, "enrollment_count": 44, "start_date": "2019-07-26", "completion_date": "2020-10-31", "has_results": false, "last_update_posted_date": "2022-02-07", "last_synced_at": "2026-05-22T09:46:40.680Z", "location_count": 1, "location_summary": "Baltimore, Maryland", "locations": [ { "city": "Baltimore", "state": "Maryland" } ], "official_url": "https://clinicaltrials.gov/study/NCT04015115" }, { "nct_id": "NCT05614544", "title": "Dose-Finding and Human Abuse Potential Study Of HSK3486 Injection In Nondependent, Recreational Central Nervous System Depressant Users", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "General Anesthesia" ], "interventions": [ { "name": "HSK3486", "type": "DRUG" }, { "name": "Propofol", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Haisco-USA Pharmaceuticals, Inc.", "sponsor_class": "INDUSTRY", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "55 Years", "sex": "ALL", "summary": "18 Years to 55 Years" }, "enrollment_count": 42, "start_date": "2022-08-16", "completion_date": "2023-10-03", "has_results": false, "last_update_posted_date": "2023-10-13", "last_synced_at": "2026-05-22T09:46:40.680Z", "location_count": 1, "location_summary": "Salt Lake City, Utah", "locations": [ { "city": "Salt Lake City", "state": "Utah" } ], "official_url": "https://clinicaltrials.gov/study/NCT05614544" } ] }