{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Central+Nervous+System+Depression&page=2", "query": { "condition": "Central Nervous System Depression", "page": 2 }, "page_size": 10 }, "pagination": { "page": 2, "page_size": 10, "total_count": 10, "total_pages": 1, "next_page_url": null, "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Central+Nervous+System+Depression&page=1&page_size=10" }, "source": "remote", "last_synced_at": "2026-06-10T05:27:11.306Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT02176226", "title": "IntelliCare: Artificial Intelligence in a Mobile Intervention for Depression and Anxiety (AIM)", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Major Depressive Disorder", "Anxiety Disorders" ], "interventions": [ { "name": "IntelliCare", "type": "BEHAVIORAL" } ], "intervention_types": [ "BEHAVIORAL" ], "sponsor": "Northwestern University", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "19 Years", "maximum_age": null, "sex": "ALL", "summary": "19 Years and older" }, "enrollment_count": 105, "start_date": "2015-03", "completion_date": "2016-06", "has_results": true, "last_update_posted_date": "2023-04-26", "last_synced_at": "2026-06-10T05:27:11.306Z", "location_count": 1, "location_summary": "Chicago, Illinois", "locations": [ { "city": "Chicago", "state": "Illinois" } ], "official_url": "https://clinicaltrials.gov/study/NCT02176226" }, { "nct_id": "NCT03944447", "title": "Outcomes Mandate National Integration With Cannabis as Medicine", "overall_status": "UNKNOWN", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Chronic Pain", "Chronic Pain Syndrome", "Chronic Pain Due to Injury", "Chronic Pain Due to Trauma", "Fibromyalgia", "Seizures", "Hepatitis C", "Cancer", "Crohn Disease", "HIV/AIDS", "Multiple Sclerosis", "Traumatic Brain Injury", "Sickle Cell Disease", "Post Traumatic Stress Disorder", "Tourette Syndrome", "Ulcerative Colitis", "Glaucoma", "Epilepsy", "Inflammatory Bowel Diseases", "Parkinson Disease", "Amyotrophic Lateral Sclerosis", "Chronic Traumatic Encephalopathy", "Anxiety", "Depression", "Insomnia", "Autism", "Opioid-use Disorder", "Bipolar Disorder", "Covid19", "SARS-CoV Infection", "COVID-19", "Corona Virus Infection", "Coronavirus" ], "interventions": [ { "name": "Cannabis, Medical", "type": "DRUG" }, { "name": "RYAH-Medtech Inhaler", "type": "DEVICE" } ], "intervention_types": [ "DRUG", "DEVICE" ], "sponsor": "OMNI Medical Services, LLC", "sponsor_class": "NETWORK", "healthy_volunteers": true, "eligibility": { "minimum_age": "7 Years", "maximum_age": null, "sex": "ALL", "summary": "7 Years and older" }, "enrollment_count": 200000, "start_date": "2018-12-01", "completion_date": "2025-12-31", "has_results": false, "last_update_posted_date": "2022-06-02", "last_synced_at": "2026-06-10T05:27:11.306Z", "location_count": 17, "location_summary": "Boca Raton, Florida • Bradenton, Florida • Fort Lauderdale, Florida + 13 more", "locations": [ { "city": "Boca Raton", "state": "Florida" }, { "city": "Bradenton", "state": "Florida" }, { "city": "Fort Lauderdale", "state": "Florida" }, { "city": "Fort Myers", "state": "Florida" }, { "city": "Gainesville", "state": "Florida" } ], "official_url": "https://clinicaltrials.gov/study/NCT03944447" }, { "nct_id": "NCT05176392", "title": "Combined Transcranial Magnetic Stimulation and Therapy for MTBI Related Headaches", "overall_status": "RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "TBI (Traumatic Brain Injury)", "Headache", "Depression" ], "interventions": [ { "name": "Active rTMS", "type": "DEVICE" }, { "name": "Headache Management Therapy", "type": "BEHAVIORAL" }, { "name": "Sham rTMS", "type": "DEVICE" }, { "name": "Headache Education Control", "type": "BEHAVIORAL" } ], "intervention_types": [ "DEVICE", "BEHAVIORAL" ], "sponsor": "Veterans Medical Research Foundation", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "65 Years", "sex": "ALL", "summary": "18 Years to 65 Years" }, "enrollment_count": 240, "start_date": "2022-01-01", "completion_date": "2025-08-31", "has_results": false, "last_update_posted_date": "2024-11-21", "last_synced_at": "2026-06-10T05:27:11.306Z", "location_count": 1, "location_summary": "San Diego, California", "locations": [ { "city": "San Diego", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT05176392" }, { "nct_id": "NCT01931644", "title": "At-Home Research Study for Patients With Autoimmune, Inflammatory, Genetic, Hematological, Infectious, Neurological, CNS, Oncological, Respiratory, Metabolic Conditions", "overall_status": "COMPLETED", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "All Diagnosed Health Conditions", "ADD/ADHD", "Alopecia Areata", "Ankylosing Spondylitis", "Asthma", "Atopic Dermatitis Eczema", "Beta Thalassemia", "Bipolar Disorder", "Breast Cancer", "Celiac Disease", "Cervical Cancer", "Chronic Inflammatory Demyelinating Polyneuropathy", "Chronic Kidney Diseases", "Chronic Obstructive Pulmonary Disease", "Colon Cancer", "Colorectal Cancer", "Crohn's Disease", "Cystic Fibrosis", "Depression", "Diabetes Mellitus", "Duchenne Muscular Dystrophy", "Endometriosis", "Epilepsy", "Facioscapulohumeral Muscular Dystrophy", "G6PD Deficiency", "General Anxiety Disorder", "Hepatitis B", "Hereditary Hemorrhagic Telangiectasia", "HIV/AIDS", "Human Papilloma Virus", "Huntington's Disease", "Idiopathic Thrombocytopenic Purpura", "Insomnia", "Kidney Cancer", "Leukemia", "Lung Cancer", "Lupus Nephritis", "Lymphoma", "Melanoma", "Multiple Myeloma", "Multiple Sclerosis", "Myositis", "Myotonic Dystrophy", "Ovarian Cancer", "Pancreatic Cancer", "Parkinson's Disease", "Polycystic Kidney Diseases", "Prostate Cancer", "Psoriasis", "Psoriatic Arthritis", "Rosacea", "Scleroderma", "Sickle Cell Anemia", "Sickle Cell Trait", "Sjogren's Syndrome", "Skin Cancer", "Spinal Muscular Atrophy", "Systemic Lupus Erythematosus", "Thrombotic Thrombocytopenic Purpura", "Trisomy 21", "Ulcerative Colitis" ], "interventions": [], "intervention_types": [], "sponsor": "Sanguine Biosciences", "sponsor_class": "INDUSTRY", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "100 Years", "sex": "ALL", "summary": "18 Years to 100 Years" }, "enrollment_count": 17667, "start_date": "2013-07", "completion_date": "2024-04", "has_results": false, "last_update_posted_date": "2024-04-18", "last_synced_at": "2026-06-10T05:27:11.306Z", "location_count": 1, "location_summary": "Los Angeles, California", "locations": [ { "city": "Los Angeles", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT01931644" }, { "nct_id": "NCT03274817", "title": "A Proof of Concept Study of the Prevention of Mild Cognitive Impairment and Eventual Alzheimer's Disease Using F18 Flutemetamol", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "Alzheimer Disease" ], "interventions": [ { "name": "Escitalopram Pill", "type": "DRUG" }, { "name": "Venlafaxine Pill", "type": "DRUG" }, { "name": "Placebo Oral Tablet", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "NYU Langone Health", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "60 Years", "maximum_age": "80 Years", "sex": "ALL", "summary": "60 Years to 80 Years" }, "enrollment_count": 5, "start_date": "2009-06-18", "completion_date": "2019-09-25", "has_results": false, "last_update_posted_date": "2020-06-02", "last_synced_at": "2026-06-10T05:27:11.306Z", "location_count": 1, "location_summary": "New York, New York", "locations": [ { "city": "New York", "state": "New York" } ], "official_url": "https://clinicaltrials.gov/study/NCT03274817" }, { "nct_id": "NCT01141647", "title": "SCI-VIP: Predictive Outcome Model Over Time for Employment (PrOMOTE)", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Spinal Cord Injuries" ], "interventions": [ { "name": "Vocational Rehabilitation", "type": "BEHAVIORAL" } ], "intervention_types": [ "BEHAVIORAL" ], "sponsor": "VA Office of Research and Development", "sponsor_class": "FED", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "65 Years", "sex": "ALL", "summary": "18 Years to 65 Years" }, "enrollment_count": 1047, "start_date": "2011-08", "completion_date": "2015-03", "has_results": true, "last_update_posted_date": "2017-05-11", "last_synced_at": "2026-06-10T05:27:11.306Z", "location_count": 7, "location_summary": "Palo Alto, California • Tampa, Florida • Boston, Massachusetts + 4 more", "locations": [ { "city": "Palo Alto", "state": "California" }, { "city": "Tampa", "state": "Florida" }, { "city": "Boston", "state": "Massachusetts" }, { "city": "Cleveland", "state": "Ohio" }, { "city": "Dallas", "state": "Texas" } ], "official_url": "https://clinicaltrials.gov/study/NCT01141647" }, { "nct_id": "NCT05335850", "title": "Yoga for Mental Health in Parkinson's Patients", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Stress", "Anxiety", "Depression", "Parkinson Disease" ], "interventions": [ { "name": "Isha Kriya", "type": "BEHAVIORAL" }, { "name": "Nadi Shuddhi", "type": "BEHAVIORAL" }, { "name": "Nada Yoga", "type": "BEHAVIORAL" }, { "name": "Routine Daily Activity", "type": "OTHER" } ], "intervention_types": [ "BEHAVIORAL", "OTHER" ], "sponsor": "Beth Israel Deaconess Medical Center", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 48, "start_date": "2022-10-18", "completion_date": "2024-09-25", "has_results": false, "last_update_posted_date": "2025-02-06", "last_synced_at": "2026-06-10T05:27:11.306Z", "location_count": 1, "location_summary": "Boston, Massachusetts", "locations": [ { "city": "Boston", "state": "Massachusetts" } ], "official_url": "https://clinicaltrials.gov/study/NCT05335850" }, { "nct_id": "NCT05576467", "title": "Treatment for Migraine and Mood", "overall_status": "ACTIVE_NOT_RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Migraine", "Depressive Symptoms" ], "interventions": [ { "name": "MBCT-Telephone", "type": "BEHAVIORAL" }, { "name": "MBCT-Video", "type": "BEHAVIORAL" }, { "name": "Enhanced Usual Care (EUC)", "type": "BEHAVIORAL" } ], "intervention_types": [ "BEHAVIORAL" ], "sponsor": "Amanda Shallcross", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 145, "start_date": "2024-03-17", "completion_date": "2026-10-20", "has_results": false, "last_update_posted_date": "2026-04-21", "last_synced_at": "2026-06-10T05:27:11.306Z", "location_count": 3, "location_summary": "The Bronx, New York • Winston-Salem, North Carolina • Cleveland, Ohio", "locations": [ { "city": "The Bronx", "state": "New York" }, { "city": "Winston-Salem", "state": "North Carolina" }, { "city": "Cleveland", "state": "Ohio" } ], "official_url": "https://clinicaltrials.gov/study/NCT05576467" }, { "nct_id": "NCT07610369", "title": "The Efficacy of Psilocybin Therapy for Depression in Parkinson's Disease", "overall_status": "NOT_YET_RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Depression", "Parkinson's Disease (PD)" ], "interventions": [ { "name": "Psilocybin (drug)", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Yale University", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "40 Years", "maximum_age": "80 Years", "sex": "ALL", "summary": "40 Years to 80 Years" }, "enrollment_count": 40, "start_date": "2026-05", "completion_date": "2030-05", "has_results": false, "last_update_posted_date": "2026-05-28", "last_synced_at": "2026-06-10T05:27:11.306Z", "location_count": 1, "location_summary": "New Haven, Connecticut", "locations": [ { "city": "New Haven", "state": "Connecticut" } ], "official_url": "https://clinicaltrials.gov/study/NCT07610369" }, { "nct_id": "NCT00086190", "title": "Study of Antidepressants in Parkinson's Disease", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Parkinson Disease", "Depression" ], "interventions": [ { "name": "paroxetine", "type": "DRUG" }, { "name": "venlafaxine", "type": "DRUG" }, { "name": "placebo", "type": "OTHER" } ], "intervention_types": [ "DRUG", "OTHER" ], "sponsor": "University of Rochester", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "30 Years", "maximum_age": null, "sex": "ALL", "summary": "30 Years and older" }, "enrollment_count": 115, "start_date": "2005-06", "completion_date": "2009-11", "has_results": true, "last_update_posted_date": "2013-01-04", "last_synced_at": "2026-06-10T05:27:11.306Z", "location_count": 15, "location_summary": "San Francisco, California • Gainesville, Florida • Miami, Florida + 11 more", "locations": [ { "city": "San Francisco", "state": "California" }, { "city": "Gainesville", "state": "Florida" }, { "city": "Miami", "state": "Florida" }, { "city": "Atlanta", "state": "Georgia" }, { "city": "Lexington", "state": "Kentucky" } ], "official_url": "https://clinicaltrials.gov/study/NCT00086190" } ] }