{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Charcot+Marie+Tooth+Disease", "query": { "condition": "Charcot Marie Tooth Disease" }, "page_size": 10 }, "pagination": { "page": 1, "page_size": 10, "total_count": 71, "total_pages": 8, "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Charcot+Marie+Tooth+Disease&page=2&page_size=10", "previous_page_url": null }, "source": "remote", "last_synced_at": "2026-06-26T15:03:46.019Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT05457023", "title": "Plasma Neurofilament Light and Its Relationship With Omega-3 Status and Soccer Heading in Women Soccer Players", "overall_status": "COMPLETED", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Brain Trauma" ], "interventions": [ { "name": "Plasma Neurofilament Light (NF-L)", "type": "OTHER" }, { "name": "Omega-3 Index", "type": "OTHER" }, { "name": "HeadCount Questionnaire", "type": "OTHER" } ], "intervention_types": [ "OTHER" ], "sponsor": "University of Kansas Medical Center", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "25 Years", "sex": "FEMALE", "summary": "18 Years to 25 Years · Female only" }, "enrollment_count": 27, "start_date": "2022-07-28", "completion_date": "2023-11-09", "has_results": false, "last_update_posted_date": "2023-11-13", "last_synced_at": "2026-06-26T15:03:46.019Z", "location_count": 2, "location_summary": "Kansas City, Missouri", "locations": [ { "city": "Kansas City", "state": "Missouri" }, { "city": "Kansas City", "state": "Missouri" } ], "official_url": "https://clinicaltrials.gov/study/NCT05457023" }, { "nct_id": "NCT03047369", "title": "The Myelin Disorders Biorepository Project", "overall_status": "RECRUITING", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Leukodystrophy", "White Matter Disease", "Leukoencephalopathies", "4H Syndrome", "Adrenoleukodystrophy", "AMN", "ALD", "ALD Gene Mutation", "ALD (Adrenoleukodystrophy)", "X-linked Adrenoleukodystrophy", "X-ALD", "Adrenomyeloneuropathy", "Aicardi Goutieres Syndrome", "AGS", "Alexander Disease", "Alexanders Leukodystrophy", "AxD", "ADLD", "Canavan Disease", "CTX", "Cerebrotendinous Xanthomatoses", "Krabbe Disease", "GALC Deficiency", "Globoid Leukodystrophy", "TUBB4A-Related Leukodystrophy", "H-ABC - Hypomyelination, Atrophy of Basal Ganglia and Cerebellum", "HBSL", "HBSL - Hypomyelination, Brain Stem, Spinal Cord, Leg Spasticity", "LBSL", "Leukoencephalopathy With Brain Stem and Spinal Cord Involvement and High Lactate Syndrome (Disorder)", "Leukoencephalopathy With Brainstem and Spinal Cord Involvement and Lactate Elevation", "ALSP", "CSF1R Gene Mutation", "HCC - Hypomyelination and Congenital Cataract", "MLC1", "Megalencephalic Leukoencephalopathy With Subcortical Cysts", "MLD", "Metachromatic Leukodystrophy", "PMD", "Pelizaeus-Merzbacher Disease", "PLP1 Null Syndrome", "PLP1 Gene Duplication | Blood or Tissue | Mutations", "Pelizaeus Merzbacher Like Disease", "Peroxisomal Biogenesis Disorder", "Zellweger Syndrome", "Refsum Disease", "Salla Disease", "Sialic Storage Disease", "Sjögren", "Sjogren-Larsson Syndrome", "Van Der Knapp Disease", "Vanishing White Matter Disease", "Charcot-Marie-Tooth", "CMT", "Mct8 (Slc16A2)-Specific Thyroid Hormone Cell Transporter Deficiency", "Allan-Herndon-Dudley Syndrome", "Cadasil", "Cockayne Syndrome", "Multiple Sulfatase Deficiency", "Gangliosidoses", "GM2 Gangliosidosis", "BPAN", "Labrune Syndrome", "LCC", "Mucopolysaccharidoses", "TBCK-Related Intellectual Disability Syndrome" ], "interventions": [], "intervention_types": [], "sponsor": "Children's Hospital of Philadelphia", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": null, "maximum_age": null, "sex": "ALL", "summary": "Not listed" }, "enrollment_count": 12000, "start_date": "2016-12-08", "completion_date": "2030-12-08", "has_results": false, "last_update_posted_date": "2025-10-23", "last_synced_at": "2026-06-26T15:03:46.019Z", "location_count": 23, "location_summary": "Los Angeles, California • Orange, California • Palo Alto, California + 18 more", "locations": [ { "city": "Los Angeles", "state": "California" }, { "city": "Orange", "state": "California" }, { "city": "Palo Alto", "state": "California" }, { "city": "Sacramento", "state": "California" }, { "city": "San Diego", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT03047369" }, { "nct_id": "NCT06592014", "title": "Lithium for Parkinson's: an Extension Trial", "overall_status": "ENROLLING_BY_INVITATION", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1", "PHASE2" ], "conditions": [ "Parkinson Disease" ], "interventions": [ { "name": "Lithium aspartate", "type": "DIETARY_SUPPLEMENT" } ], "intervention_types": [ "DIETARY_SUPPLEMENT" ], "sponsor": "State University of New York at Buffalo", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "45 Years", "maximum_age": "80 Years", "sex": "ALL", "summary": "45 Years to 80 Years" }, "enrollment_count": 35, "start_date": "2024-08-09", "completion_date": "2026-11-01", "has_results": false, "last_update_posted_date": "2025-11-19", "last_synced_at": "2026-06-26T15:03:46.019Z", "location_count": 1, "location_summary": "Williamsville, New York", "locations": [ { "city": "Williamsville", "state": "New York" } ], "official_url": "https://clinicaltrials.gov/study/NCT06592014" }, { "nct_id": "NCT05156281", "title": "Efficacy and Safety of Remibrutinib Compared to Teriflunomide in Participants With Relapsing Multiple Sclerosis (RMS)", "overall_status": "ACTIVE_NOT_RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Relapsing Multiple Sclerosis" ], "interventions": [ { "name": "Remibrutinib", "type": "DRUG" }, { "name": "Teriflunomide", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Novartis Pharmaceuticals", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "55 Years", "sex": "ALL", "summary": "18 Years to 55 Years" }, "enrollment_count": 1007, "start_date": "2021-12-13", "completion_date": "2030-10-30", "has_results": false, "last_update_posted_date": "2026-06-24", "last_synced_at": "2026-06-26T15:03:46.019Z", "location_count": 50, "location_summary": "Phoenix, Arizona • Hanford, California • Los Angeles, California + 42 more", "locations": [ { "city": "Phoenix", "state": "Arizona" }, { "city": "Hanford", "state": "California" }, { "city": "Los Angeles", "state": "California" }, { "city": "West Hollywood", "state": "California" }, { "city": "Aurora", "state": "Colorado" } ], "official_url": "https://clinicaltrials.gov/study/NCT05156281" }, { "nct_id": "NCT01203085", "title": "Development of Charcot Marie Tooth Disease (CMT) Pediatric Scale for Children With CMT", "overall_status": "COMPLETED", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Charcot Marie Tooth Disease" ], "interventions": [], "intervention_types": [], "sponsor": "University of Iowa", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": null, "maximum_age": "21 Years", "sex": "ALL", "summary": "Up to 21 Years" }, "enrollment_count": 500, "start_date": "2010-04", "completion_date": "2025-09", "has_results": false, "last_update_posted_date": "2025-10-07", "last_synced_at": "2026-06-26T15:03:46.019Z", "location_count": 9, "location_summary": "Palo Alto, California • Hartford, Connecticut • Orlando, Florida + 6 more", "locations": [ { "city": "Palo Alto", "state": "California" }, { "city": "Hartford", "state": "Connecticut" }, { "city": "Orlando", "state": "Florida" }, { "city": "Iowa City", "state": "Iowa" }, { "city": "Ann Arbor", "state": "Michigan" } ], "official_url": "https://clinicaltrials.gov/study/NCT01203085" }, { "nct_id": "NCT02859428", "title": "Disease Natural History and Biomarkers of SPG3A, SPG4A, and SPG31", "overall_status": "TERMINATED", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Hereditary Spastic Paraplegia" ], "interventions": [], "intervention_types": [], "sponsor": "National Institute of Neurological Disorders and Stroke (NINDS)", "sponsor_class": "NIH", "healthy_volunteers": false, "eligibility": { "minimum_age": "7 Years", "maximum_age": null, "sex": "ALL", "summary": "7 Years and older" }, "enrollment_count": 51, "start_date": "2016-11-18", "completion_date": "2020-10-16", "has_results": false, "last_update_posted_date": "2020-10-20", "last_synced_at": "2026-06-26T15:03:46.019Z", "location_count": 1, "location_summary": "Bethesda, Maryland", "locations": [ { "city": "Bethesda", "state": "Maryland" } ], "official_url": "https://clinicaltrials.gov/study/NCT02859428" }, { "nct_id": "NCT02532244", "title": "Genetics of Pediatric-Onset Motor Neuron and Neuromuscular Diseases", "overall_status": "COMPLETED", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Spinal Muscular Atrophy", "Charcot-Marie-Tooth Disease", "Muscular Dystrophy", "Spinal Muscular Atrophy With Respiratory Distress 1", "Amyotrophic Lateral Sclerosis", "Motor Neuron Disease", "Neuromuscular Disease", "Peroneal Muscular Atrophy" ], "interventions": [ { "name": "sample collection", "type": "OTHER" } ], "intervention_types": [ "OTHER" ], "sponsor": "Nemours Children's Clinic", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "1 Month", "maximum_age": null, "sex": "ALL", "summary": "1 Month and older" }, "enrollment_count": 230, "start_date": "2015-06", "completion_date": "2024-12-18", "has_results": false, "last_update_posted_date": "2024-12-19", "last_synced_at": "2026-06-26T15:03:46.019Z", "location_count": 3, "location_summary": "Wilmington, Delaware • Jacksonville, Florida • Orlando, Florida", "locations": [ { "city": "Wilmington", "state": "Delaware" }, { "city": "Jacksonville", "state": "Florida" }, { "city": "Orlando", "state": "Florida" } ], "official_url": "https://clinicaltrials.gov/study/NCT02532244" }, { "nct_id": "NCT06482437", "title": "Safety and Efficacy of NMD670 in Adult Patients With Type 1 and Type 2 Charcot-Marie-Tooth Disease", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Charcot-Marie-Tooth Disease" ], "interventions": [ { "name": "NMD670", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "NMD Pharma A/S", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "70 Years", "sex": "ALL", "summary": "18 Years to 70 Years" }, "enrollment_count": 81, "start_date": "2024-09-30", "completion_date": "2025-11-04", "has_results": false, "last_update_posted_date": "2025-11-12", "last_synced_at": "2026-06-26T15:03:46.019Z", "location_count": 8, "location_summary": "Kansas City, Kansas • Boston, Massachusetts • Columbia, Missouri + 5 more", "locations": [ { "city": "Kansas City", "state": "Kansas" }, { "city": "Boston", "state": "Massachusetts" }, { "city": "Columbia", "state": "Missouri" }, { "city": "New York", "state": "New York" }, { "city": "Rochester", "state": "New York" } ], "official_url": "https://clinicaltrials.gov/study/NCT06482437" }, { "nct_id": "NCT02579759", "title": "Phase III Trial Assessing the Efficacy and Safety of PXT3003 in CMT1A Patients (PLEO-CMT)", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Charcot-Marie-Tooth Disease Type 1A" ], "interventions": [ { "name": "PXT3003 dose 1", "type": "DRUG" }, { "name": "PXT3003 dose 2", "type": "DRUG" }, { "name": "placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Pharnext S.C.A.", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "16 Years", "maximum_age": "65 Years", "sex": "ALL", "summary": "16 Years to 65 Years" }, "enrollment_count": 323, "start_date": "2015-12", "completion_date": "2018-08", "has_results": true, "last_update_posted_date": "2020-02-27", "last_synced_at": "2026-06-26T15:03:46.019Z", "location_count": 11, "location_summary": "Los Angeles, California • New Britain, Connecticut • Gainesville, Florida + 8 more", "locations": [ { "city": "Los Angeles", "state": "California" }, { "city": "New Britain", "state": "Connecticut" }, { "city": "Gainesville", "state": "Florida" }, { "city": "Kansas City", "state": "Kansas" }, { "city": "Boston", "state": "Massachusetts" } ], "official_url": "https://clinicaltrials.gov/study/NCT02579759" }, { "nct_id": "NCT07223632", "title": "Treatment of Charcot-Marie-Tooth Disease, Axonal, Type 2S (CMT2S) in an Individual Patient", "overall_status": "ACTIVE_NOT_RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1", "PHASE2" ], "conditions": [ "Charcot Marie Tooth Disease (CMT)", "Neuromuscular Diseases (NMD)" ], "interventions": [ { "name": "VCA-894A", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Vanda Pharmaceuticals", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": null, "maximum_age": null, "sex": "FEMALE", "summary": "Female only" }, "enrollment_count": 1, "start_date": "2025-05-13", "completion_date": "2026-03", "has_results": false, "last_update_posted_date": "2025-11-03", "last_synced_at": "2026-06-26T15:03:46.019Z", "location_count": 1, "location_summary": "Madison, Wisconsin", "locations": [ { "city": "Madison", "state": "Wisconsin" } ], "official_url": "https://clinicaltrials.gov/study/NCT07223632" } ] }