{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Charcot+Marie+Tooth+Disease&page=3", "query": { "condition": "Charcot Marie Tooth Disease", "page": 3 }, "page_size": 10 }, "pagination": { "page": 3, "page_size": 10, "total_count": 73, "total_pages": 8, "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Charcot+Marie+Tooth+Disease&page=4&page_size=10", "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Charcot+Marie+Tooth+Disease&page=2&page_size=10" }, "source": "remote", "last_synced_at": "2026-10-03T03:19:59.717Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT02429947", "title": "An Analysis of the Symptomatic Domains Most Relevant to Charcot Marie Tooth Neuropathy (CMT) Patients", "overall_status": "COMPLETED", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Charcot Marie Tooth Disease (CMT)", "Hereditary Sensory and Motor Neuropathy", "Nerve Compression Syndromes", "Tooth Diseases", "Congenital Abnormalities", "Genetic Diseases, Inborn", "Heredodegenerative Disorders, Nervous System" ], "interventions": [], "intervention_types": [], "sponsor": "University of South Florida", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 411, "start_date": "2012-07", "completion_date": "2013-06", "has_results": false, "last_update_posted_date": "2017-06-14", "last_synced_at": "2026-10-03T03:19:59.717Z", "location_count": 1, "location_summary": "Tampa, Florida", "locations": [ { "city": "Tampa", "state": "Florida" } ], "official_url": "https://clinicaltrials.gov/study/NCT02429947" }, { "nct_id": "NCT02699190", "title": "LeukoSEQ: Whole Genome Sequencing as a First-Line Diagnostic Tool for Leukodystrophies", "overall_status": "COMPLETED", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Leukodystrophy", "White Matter Disease", "4H Syndrome", "Adrenoleukodystrophy", "AMN", "ALD", "ALD (Adrenoleukodystrophy)", "X-linked Adrenoleukodystrophy", "X-ALD", "Adrenomyeloneuropathy", "Aicardi Goutieres Syndrome", "AGS", "Alexander Disease", "Alexanders Leukodystrophy", "AxD", "ADLD", "Canavan Disease", "CTX", "Cerebrotendinous Xanthomatoses", "Krabbe Disease", "GALC Deficiency", "Globoid Leukodystrophy", "TUBB4A-Related Leukodystrophy", "H-ABC - Hypomyelination, Atrophy of Basal Ganglia and Cerebellum", "HBSL", "HBSL - Hypomyelination, Brain Stem, Spinal Cord, Leg Spasticity", "LBSL", "Leukoencephalopathy With Brain Stem and Spinal Cord Involvement and High Lactate Syndrome (Disorder)", "Leukoencephalopathy With Brainstem and Spinal Cord Involvement and Lactate Elevation", "ALSP", "CSF1R Gene Mutation", "HCC - Hypomyelination and Congenital Cataract", "MLC1", "Megalencephalic Leukoencephalopathy With Subcortical Cysts 1", "MLD", "Metachromatic Leukodystrophy", "PMD", "Pelizaeus-Merzbacher Disease", "PLP1 Null Syndrome", "PLP1 Gene Duplication | Blood or Tissue | Mutations", "Pelizaeus-Merzbacher-Like Disease, 1", "Peroxisomal Biogenesis Disorder", "Zellweger Syndrome", "Refsum Disease", "Salla Disease", "Sialic Storage Disease", "Sjögren", "Sjogren-Larsson Syndrome", "Van Der Knapp Disease", "Vanishing White Matter Disease", "Charcot-Marie-Tooth", "CMT", "Mct8 (Slc16A2)-Specific Thyroid Hormone Cell Transporter Deficiency", "Allan-Herndon-Dudley Syndrome", "Cadasil", "Cockayne Syndrome", "Multiple Sulfatase Deficiency", "Gangliosidoses", "GM2 Gangliosidosis", "BPAN", "Labrune Syndrome", "LCC", "Mucopolysaccharidoses", "TBCK-Related Intellectual Disability Syndrome" ], "interventions": [], "intervention_types": [], "sponsor": "Children's Hospital of Philadelphia", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": null, "maximum_age": "18 Years", "sex": "ALL", "summary": "Up to 18 Years" }, "enrollment_count": 236, "start_date": "2017-01-06", "completion_date": "2024-10-31", "has_results": true, "last_update_posted_date": "2025-11-10", "last_synced_at": "2026-10-03T03:19:59.717Z", "location_count": 1, "location_summary": "Philadelphia, Pennsylvania", "locations": [ { "city": "Philadelphia", "state": "Pennsylvania" } ], "official_url": "https://clinicaltrials.gov/study/NCT02699190" }, { "nct_id": "NCT05827419", "title": "Hearing and Balance Disorders in Peripheral Neuropathy", "overall_status": "TERMINATED", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Charcot-Marie-Tooth Disease" ], "interventions": [], "intervention_types": [], "sponsor": "Nemours Children's Clinic", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "5 Years", "maximum_age": "21 Years", "sex": "ALL", "summary": "5 Years to 21 Years" }, "enrollment_count": 1, "start_date": "2018-06-01", "completion_date": "2023-03-10", "has_results": false, "last_update_posted_date": "2023-04-25", "last_synced_at": "2026-10-03T03:19:59.717Z", "location_count": 1, "location_summary": "Wilmington, Delaware", "locations": [ { "city": "Wilmington", "state": "Delaware" } ], "official_url": "https://clinicaltrials.gov/study/NCT05827419" }, { "nct_id": "NCT02561702", "title": "Mexiletine for Muscle Cramps in Charcot Marie Tooth Disease", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Charcot Marie Tooth Disease" ], "interventions": [ { "name": "Placebo", "type": "OTHER" }, { "name": "Mexiletine", "type": "DRUG" } ], "intervention_types": [ "OTHER", "DRUG" ], "sponsor": "University of Rochester", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 4, "start_date": "2015-09", "completion_date": "2016-12-31", "has_results": true, "last_update_posted_date": "2018-03-26", "last_synced_at": "2026-10-03T03:19:59.717Z", "location_count": 1, "location_summary": "Rochester, New York", "locations": [ { "city": "Rochester", "state": "New York" } ], "official_url": "https://clinicaltrials.gov/study/NCT02561702" }, { "nct_id": "NCT00484510", "title": "High Dose Ascorbic Acid Treatment of CMT1A", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2", "PHASE3" ], "conditions": [ "Charcot-Marie-Tooth Disease, Type Ia" ], "interventions": [ { "name": "Ascorbic acid (Vitamin C)", "type": "DRUG" }, { "name": "placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Wayne State University", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "13 Years", "maximum_age": "70 Years", "sex": "ALL", "summary": "13 Years to 70 Years" }, "enrollment_count": 110, "start_date": "2007-04", "completion_date": "2012-12", "has_results": false, "last_update_posted_date": "2013-03-06", "last_synced_at": "2026-10-03T03:19:59.717Z", "location_count": 3, "location_summary": "Baltimore, Maryland • Detroit, Michigan • Rochester, New York", "locations": [ { "city": "Baltimore", "state": "Maryland" }, { "city": "Detroit", "state": "Michigan" }, { "city": "Rochester", "state": "New York" } ], "official_url": "https://clinicaltrials.gov/study/NCT00484510" }, { "nct_id": "NCT05317390", "title": "Clinical Validation of DystoniaNet Deep Learning Platform for Diagnosis of Isolated Dystonia", "overall_status": "RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Dystonia", "Drug Induced Dystonia", "Parkinson Disease", "Essential Tremor", "Dyskinesias", "Myoclonus", "Tic Disorders", "Torticollis", "Ulnar Nerve Entrapment", "Temporomandibular Joint Disorders", "Dysphonia" ], "interventions": [ { "name": "DystoniaNet-based diagnosis of isolated dystonia", "type": "DIAGNOSTIC_TEST" } ], "intervention_types": [ "DIAGNOSTIC_TEST" ], "sponsor": "Massachusetts Eye and Ear Infirmary", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": null, "maximum_age": null, "sex": "ALL", "summary": "Not listed" }, "enrollment_count": 1000, "start_date": "2022-06-01", "completion_date": "2028-04-30", "has_results": false, "last_update_posted_date": "2025-12-02", "last_synced_at": "2026-10-03T03:19:59.717Z", "location_count": 1, "location_summary": "Boston, Massachusetts", "locations": [ { "city": "Boston", "state": "Massachusetts" } ], "official_url": "https://clinicaltrials.gov/study/NCT05317390" }, { "nct_id": "NCT03023540", "title": "Assessing Long Term Safety and Tolerability of PXT3003 in Patients With Charcot-Marie-Tooth Disease Type 1A", "overall_status": "UNKNOWN", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Charcot-Marie-Tooth Disease, Type IA" ], "interventions": [ { "name": "PXT3003", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Pharnext S.C.A.", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "17 Years", "maximum_age": "67 Years", "sex": "ALL", "summary": "17 Years to 67 Years" }, "enrollment_count": 187, "start_date": "2017-03-07", "completion_date": "2024-12-31", "has_results": false, "last_update_posted_date": "2024-02-20", "last_synced_at": "2026-10-03T03:19:59.717Z", "location_count": 9, "location_summary": "Los Angeles, California • Gainesville, Florida • Kansas City, Kansas + 6 more", "locations": [ { "city": "Los Angeles", "state": "California" }, { "city": "Gainesville", "state": "Florida" }, { "city": "Kansas City", "state": "Kansas" }, { "city": "Boston", "state": "Massachusetts" }, { "city": "Ann Arbor", "state": "Michigan" } ], "official_url": "https://clinicaltrials.gov/study/NCT03023540" }, { "nct_id": "NCT01193088", "title": "Genetics of Charcot Marie Tooth (CMT) - Modifiers of CMT1A, New Causes of CMT2", "overall_status": "RECRUITING", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Charcot-Marie-Tooth Disease, Type Ia (Disorder)", "HMSN" ], "interventions": [], "intervention_types": [], "sponsor": "University of Iowa", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": null, "maximum_age": null, "sex": "ALL", "summary": "Not listed" }, "enrollment_count": 1050, "start_date": "2010-05", "completion_date": "2026-12", "has_results": false, "last_update_posted_date": "2025-10-07", "last_synced_at": "2026-10-03T03:19:59.717Z", "location_count": 17, "location_summary": "Los Angeles, California • Palo Alto, California • Aurora, Colorado + 13 more", "locations": [ { "city": "Los Angeles", "state": "California" }, { "city": "Palo Alto", "state": "California" }, { "city": "Aurora", "state": "Colorado" }, { "city": "Hartford", "state": "Connecticut" }, { "city": "Miami", "state": "Florida" } ], "official_url": "https://clinicaltrials.gov/study/NCT01193088" }, { "nct_id": "NCT00023075", "title": "Nuclear Magnetic Spectroscopy Imaging to Evaluate Primary Lateral Sclerosis, Hereditary Spastic Paraplegia and Amyotrophic Lateral Sclerosis", "overall_status": "COMPLETED", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Primary Lateral Sclerosis", "Hereditary Spastic Paraplegia", "Amyotrophic Lateral Sclerosis" ], "interventions": [], "intervention_types": [], "sponsor": "National Institute of Neurological Disorders and Stroke (NINDS)", "sponsor_class": "NIH", "healthy_volunteers": true, "eligibility": { "minimum_age": null, "maximum_age": null, "sex": "ALL", "summary": "Not listed" }, "enrollment_count": 55, "start_date": "2001-08", "completion_date": "2003-08", "has_results": false, "last_update_posted_date": "2008-03-04", "last_synced_at": "2026-10-03T03:19:59.717Z", "location_count": 1, "location_summary": "Bethesda, Maryland", "locations": [ { "city": "Bethesda", "state": "Maryland" } ], "official_url": "https://clinicaltrials.gov/study/NCT00023075" }, { "nct_id": "NCT03943290", "title": "Extension Study to Evaluate the Long-Term Effects of ACE-083 in Patients With Facioscapulohumeral Muscular Dystrophy (FSHD) and Charcot-Marie Tooth (CMT) Disease Types 1 and X (CMT1 and CMTX)", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Facioscapulohumeral Muscular Dystrophy", "Charcot-Marie-Tooth Disease" ], "interventions": [ { "name": "ACE-083", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Acceleron Pharma, Inc., a wholly-owned subsidiary of Merck & Co., Inc., Rahway, NJ USA", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 62, "start_date": "2019-05-10", "completion_date": "2020-03-11", "has_results": true, "last_update_posted_date": "2022-09-26", "last_synced_at": "2026-10-03T03:19:59.717Z", "location_count": 19, "location_summary": "Orange, California • Sacramento, California • Aurora, Colorado + 16 more", "locations": [ { "city": "Orange", "state": "California" }, { "city": "Sacramento", "state": "California" }, { "city": "Aurora", "state": "Colorado" }, { "city": "Gainesville", "state": "Florida" }, { "city": "Indianapolis", "state": "Indiana" } ], "official_url": "https://clinicaltrials.gov/study/NCT03943290" } ] }