{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Charcot-Marie-Tooth+Disease%2C+Type+Ia", "query": { "condition": "Charcot-Marie-Tooth Disease, Type Ia" }, "page_size": 10 }, "pagination": { "page": 1, "page_size": 10, "total_count": 9, "total_pages": 1, "next_page_url": null, "previous_page_url": null }, "source": "remote", "last_synced_at": "2026-06-26T16:29:38.354Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT02579759", "title": "Phase III Trial Assessing the Efficacy and Safety of PXT3003 in CMT1A Patients (PLEO-CMT)", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Charcot-Marie-Tooth Disease Type 1A" ], "interventions": [ { "name": "PXT3003 dose 1", "type": "DRUG" }, { "name": "PXT3003 dose 2", "type": "DRUG" }, { "name": "placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Pharnext S.C.A.", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "16 Years", "maximum_age": "65 Years", "sex": "ALL", "summary": "16 Years to 65 Years" }, "enrollment_count": 323, "start_date": "2015-12", "completion_date": "2018-08", "has_results": true, "last_update_posted_date": "2020-02-27", "last_synced_at": "2026-06-26T16:29:38.354Z", "location_count": 11, "location_summary": "Los Angeles, California • New Britain, Connecticut • Gainesville, Florida + 8 more", "locations": [ { "city": "Los Angeles", "state": "California" }, { "city": "New Britain", "state": "Connecticut" }, { "city": "Gainesville", "state": "Florida" }, { "city": "Kansas City", "state": "Kansas" }, { "city": "Boston", "state": "Massachusetts" } ], "official_url": "https://clinicaltrials.gov/study/NCT02579759" }, { "nct_id": "NCT00484510", "title": "High Dose Ascorbic Acid Treatment of CMT1A", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2", "PHASE3" ], "conditions": [ "Charcot-Marie-Tooth Disease, Type Ia" ], "interventions": [ { "name": "Ascorbic acid (Vitamin C)", "type": "DRUG" }, { "name": "placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Wayne State University", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "13 Years", "maximum_age": "70 Years", "sex": "ALL", "summary": "13 Years to 70 Years" }, "enrollment_count": 110, "start_date": "2007-04", "completion_date": "2012-12", "has_results": false, "last_update_posted_date": "2013-03-06", "last_synced_at": "2026-06-26T16:29:38.354Z", "location_count": 3, "location_summary": "Baltimore, Maryland • Detroit, Michigan • Rochester, New York", "locations": [ { "city": "Baltimore", "state": "Maryland" }, { "city": "Detroit", "state": "Michigan" }, { "city": "Rochester", "state": "New York" } ], "official_url": "https://clinicaltrials.gov/study/NCT00484510" }, { "nct_id": "NCT03520751", "title": "Phase I/IIa Trial of scAAV1.tMCK.NTF3 for Treatment of CMT1A", "overall_status": "NOT_YET_RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1", "PHASE2" ], "conditions": [ "Charcot-Marie-Tooth Neuropathy Type 1A" ], "interventions": [ { "name": "scAAV1.tMCK.NTF3", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Nationwide Children's Hospital", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "35 Years", "sex": "ALL", "summary": "18 Years to 35 Years" }, "enrollment_count": 3, "start_date": "2027-04", "completion_date": "2030-04", "has_results": false, "last_update_posted_date": "2025-06-24", "last_synced_at": "2026-06-26T16:29:38.354Z", "location_count": 1, "location_summary": "Columbus, Ohio", "locations": [ { "city": "Columbus", "state": "Ohio" } ], "official_url": "https://clinicaltrials.gov/study/NCT03520751" }, { "nct_id": "NCT03023540", "title": "Assessing Long Term Safety and Tolerability of PXT3003 in Patients With Charcot-Marie-Tooth Disease Type 1A", "overall_status": "UNKNOWN", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Charcot-Marie-Tooth Disease, Type IA" ], "interventions": [ { "name": "PXT3003", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Pharnext S.C.A.", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "17 Years", "maximum_age": "67 Years", "sex": "ALL", "summary": "17 Years to 67 Years" }, "enrollment_count": 187, "start_date": "2017-03-07", "completion_date": "2024-12-31", "has_results": false, "last_update_posted_date": "2024-02-20", "last_synced_at": "2026-06-26T16:29:38.354Z", "location_count": 9, "location_summary": "Los Angeles, California • Gainesville, Florida • Kansas City, Kansas + 6 more", "locations": [ { "city": "Los Angeles", "state": "California" }, { "city": "Gainesville", "state": "Florida" }, { "city": "Kansas City", "state": "Kansas" }, { "city": "Boston", "state": "Massachusetts" }, { "city": "Ann Arbor", "state": "Michigan" } ], "official_url": "https://clinicaltrials.gov/study/NCT03023540" }, { "nct_id": "NCT01193088", "title": "Genetics of Charcot Marie Tooth (CMT) - Modifiers of CMT1A, New Causes of CMT2", "overall_status": "RECRUITING", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Charcot-Marie-Tooth Disease, Type Ia (Disorder)", "HMSN" ], "interventions": [], "intervention_types": [], "sponsor": "University of Iowa", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": null, "maximum_age": null, "sex": "ALL", "summary": "Not listed" }, "enrollment_count": 1050, "start_date": "2010-05", "completion_date": "2026-12", "has_results": false, "last_update_posted_date": "2025-10-07", "last_synced_at": "2026-06-26T16:29:38.354Z", "location_count": 17, "location_summary": "Los Angeles, California • Palo Alto, California • Aurora, Colorado + 13 more", "locations": [ { "city": "Los Angeles", "state": "California" }, { "city": "Palo Alto", "state": "California" }, { "city": "Aurora", "state": "Colorado" }, { "city": "Hartford", "state": "Connecticut" }, { "city": "Miami", "state": "Florida" } ], "official_url": "https://clinicaltrials.gov/study/NCT01193088" }, { "nct_id": "NCT05011006", "title": "NT-3 Levels and Function in Individuals With CMT", "overall_status": "NOT_YET_RECRUITING", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Charcot-Marie-Tooth Disease", "Peripheral Neuropathy", "Chronic Inflammatory Demyelinating Polyneuropathy" ], "interventions": [ { "name": "NT3 blood draw", "type": "DIAGNOSTIC_TEST" } ], "intervention_types": [ "DIAGNOSTIC_TEST" ], "sponsor": "Zarife Sahenk", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "7 Years", "maximum_age": null, "sex": "ALL", "summary": "7 Years and older" }, "enrollment_count": 50, "start_date": "2027-11-13", "completion_date": "2030-06", "has_results": false, "last_update_posted_date": "2025-06-24", "last_synced_at": "2026-06-26T16:29:38.354Z", "location_count": 1, "location_summary": "Columbus, Ohio", "locations": [ { "city": "Columbus", "state": "Ohio" } ], "official_url": "https://clinicaltrials.gov/study/NCT05011006" }, { "nct_id": "NCT04762758", "title": "Phase III Trial Assessing the Efficacy and Safety of PXT3003 in CMT1A Patients", "overall_status": "UNKNOWN", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Charcot-Marie-Tooth Disease" ], "interventions": [ { "name": "(RS)-baclofen, naltrexone hydrochloride and D-sorbitol", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Pharnext S.C.A.", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "16 Years", "maximum_age": "65 Years", "sex": "ALL", "summary": "16 Years to 65 Years" }, "enrollment_count": 350, "start_date": "2021-03-30", "completion_date": "2024-04-19", "has_results": false, "last_update_posted_date": "2024-04-03", "last_synced_at": "2026-06-26T16:29:38.354Z", "location_count": 20, "location_summary": "Los Angeles, California • Sacramento, California • New Britain, Connecticut + 16 more", "locations": [ { "city": "Los Angeles", "state": "California" }, { "city": "Los Angeles", "state": "California" }, { "city": "Sacramento", "state": "California" }, { "city": "New Britain", "state": "Connecticut" }, { "city": "Gainesville", "state": "Florida" } ], "official_url": "https://clinicaltrials.gov/study/NCT04762758" }, { "nct_id": "NCT05902351", "title": "Natural History Study for Charcot Marie Tooth Disease", "overall_status": "RECRUITING", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Charcot-Marie-Tooth Disease", "Charcot-Marie-Tooth", "Charcot-Marie-Tooth Disease, Type IA", "Charcot-Marie-Tooth Disease Type 2A", "Charcot-Marie-Tooth Disease Type 2", "Charcot-Marie-Tooth Disease, Type 2C", "Charcot-Marie-Tooth Disease Type 2A2B", "Charcot-Marie-Tooth Disease Type 2B2", "Charcot-Marie-Tooth Disease Type 2A1", "Charcot-Marie-Tooth Disease Type 4B1", "Charcot-Marie-Tooth Disease, Type IB", "Charcot-Marie-Tooth Disease Type 2B1", "Charcot-Marie-Tooth Disease Type 2U (Diagnosis)", "Charcot-Marie-Tooth Disease Type 4A", "Charcot-Marie-Tooth Disease, Type 4A, Axonal Form", "Charcot-Marie-Tooth Disease Type 2A2A", "Charcot-Marie-Tooth Disease Type 2S (Disorder)", "Charcot-Marie-Tooth Disease and Deafness", "Charcot-Marie-Tooth Disease Type 4B2", "Charcot-Marie-Tooth Disease Type 4H", "Charcot-Marie-Tooth Disease Type 1F", "Charcot-Marie-Tooth Disease Type 4C", "Charcot-Marie-Tooth Disease Type 4E", "Charcot-Marie-Tooth Disease Type 1D", "Charcot-Marie-Tooth Disease Type 2Q (Diagnosis)", "Charcot-Marie-Tooth Disease Type 2A2", "Charcot-Marie-Tooth Disease Type 2N (Diagnosis)", "Charcot-Marie-Tooth Disease Type 2B5", "Charcot-Marie-Tooth Disease Type 2D", "Charcot-Marie-Tooth Disease Type 4D", "Charcot-Marie-Tooth Disease Type 2K", "Charcot-Marie-Tooth Disease Type 2L (Diagnosis)", "Charcot-Marie-Tooth Disease Type 2T", "Charcot-Marie-Tooth Disease Type 2I", "Charcot-Marie-Tooth Disease Type 2J", "Charcot-Marie-Tooth Disease Type 2E", "Charcot-Marie-Tooth Disease Type 2G", "Charcot-Marie-Tooth Disease Type 1C", "Charcot-Marie-Tooth Disease Type 2R", "Charcot-Marie-Tooth Disease Type 2O (Diagnosis)", "Charcot-Marie-Tooth Disease Type 2M", "Charcot-Marie-Tooth Disease Type 2P", "Charcot-Marie-Tooth Disease Type 2Y", "Charcot-Marie-Tooth Disease Type 4F (Diagnosis)", "Charcot-Marie-Tooth Disease Type 4B3", "Charcot-Marie-Tooth Disease Type 2H", "HNPP", "X-Linked Charcot-Marie-Tooth Disease" ], "interventions": [], "intervention_types": [], "sponsor": "Hereditary Neuropathy Foundation", "sponsor_class": "OTHER_GOV", "healthy_volunteers": false, "eligibility": { "minimum_age": null, "maximum_age": null, "sex": "ALL", "summary": "Not listed" }, "enrollment_count": 10000, "start_date": "2013-11-01", "completion_date": "2029-12-31", "has_results": false, "last_update_posted_date": "2024-10-01", "last_synced_at": "2026-06-26T16:29:38.354Z", "location_count": 1, "location_summary": "New York, New York", "locations": [ { "city": "New York", "state": "New York" } ], "official_url": "https://clinicaltrials.gov/study/NCT05902351" }, { "nct_id": "NCT03715283", "title": "Change in MUNIX in Patients With CMT1A Undergoing a Home Ankle Strengthening Program Versus Standard of Care", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Charcot-Marie-Tooth Disease" ], "interventions": [ { "name": "Home Ankle Strengthing Program", "type": "OTHER" }, { "name": "Standard of Care", "type": "OTHER" } ], "intervention_types": [ "OTHER" ], "sponsor": "Vanderbilt University Medical Center", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 19, "start_date": "2019-01-15", "completion_date": "2019-09-01", "has_results": false, "last_update_posted_date": "2019-12-20", "last_synced_at": "2026-06-26T16:29:38.354Z", "location_count": 1, "location_summary": "Nashville, Tennessee", "locations": [ { "city": "Nashville", "state": "Tennessee" } ], "official_url": "https://clinicaltrials.gov/study/NCT03715283" } ] }