{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Cholestasis+of+Parenteral+Nutrition&page=2",
    "query": {
      "condition": "Cholestasis of Parenteral Nutrition",
      "page": 2
    },
    "page_size": 10
  },
  "pagination": {
    "page": 2,
    "page_size": 10,
    "total_count": 10,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Cholestasis+of+Parenteral+Nutrition&page=1&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-06-10T06:24:55.665Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT01050660",
      "title": "Low Dose Parenteral Fat for Prevention of Parenteral Nutrition Associated Cholestasis in Preterm Neonates",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Parenteral Nutrition-Associated Liver Disease"
      ],
      "interventions": [
        {
          "name": "Intravenous fat emulsion",
          "type": "OTHER"
        },
        {
          "name": "Restriction of intravenous fat emulsion to 1 gm/kg/d",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Yale University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "12 Hours",
        "maximum_age": "48 Hours",
        "sex": "ALL",
        "summary": "12 Hours to 48 Hours"
      },
      "enrollment_count": 136,
      "start_date": "2009-06",
      "completion_date": "2013-01",
      "has_results": true,
      "last_update_posted_date": "2014-10-28",
      "last_synced_at": "2026-06-10T06:24:55.665Z",
      "location_count": 1,
      "location_summary": "New Haven, Connecticut",
      "locations": [
        {
          "city": "New Haven",
          "state": "Connecticut"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01050660"
    },
    {
      "nct_id": "NCT01739517",
      "title": "Efficacy and Safety of Omega-3 Lipid Therapy in Pediatric Patients With Parenteral Nutrition-Associated Liver Disease",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Short Bowel Syndrome",
        "Cholestasis"
      ],
      "interventions": [
        {
          "name": "Omegaven Therapy",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Amarnath, Rathna, M.D.",
      "sponsor_class": "INDIV",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": "1 Year",
        "sex": "ALL",
        "summary": "Up to 1 Year"
      },
      "enrollment_count": 20,
      "start_date": "2009-03",
      "completion_date": "2013-12",
      "has_results": false,
      "last_update_posted_date": "2012-12-03",
      "last_synced_at": "2026-06-10T06:24:55.665Z",
      "location_count": 1,
      "location_summary": "Columbia, South Carolina",
      "locations": [
        {
          "city": "Columbia",
          "state": "South Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01739517"
    },
    {
      "nct_id": "NCT01555957",
      "title": "Prospective Randomized Clinical Trial of Intravenous Lipids and Cholestasis",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Parenteral Nutrition Associated Cholestasis"
      ],
      "interventions": [
        {
          "name": "intravenous lipid",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of Rochester",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": "72 Hours",
        "sex": "ALL",
        "summary": "Up to 72 Hours"
      },
      "enrollment_count": 40,
      "start_date": "2012-02",
      "completion_date": "2019-01-31",
      "has_results": true,
      "last_update_posted_date": "2020-12-03",
      "last_synced_at": "2026-06-10T06:24:55.665Z",
      "location_count": 1,
      "location_summary": "Rochester, New York",
      "locations": [
        {
          "city": "Rochester",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01555957"
    },
    {
      "nct_id": "NCT00826020",
      "title": "Evaluation of Omegaven™ Parenteral Nutrition in Patients With Total Parenteral Nutrition (TPN)-Induced Cholestasis",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Parenteral Nutrition Associated Liver Disease PNALD",
        "Cholestasis"
      ],
      "interventions": [
        {
          "name": "Omegaven™",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of Nebraska",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "19 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "19 Years and older"
      },
      "enrollment_count": 72,
      "start_date": "2009-05-01",
      "completion_date": "2017-10-06",
      "has_results": true,
      "last_update_posted_date": "2023-10-05",
      "last_synced_at": "2026-06-10T06:24:55.665Z",
      "location_count": 1,
      "location_summary": "Omaha, Nebraska",
      "locations": [
        {
          "city": "Omaha",
          "state": "Nebraska"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00826020"
    },
    {
      "nct_id": "NCT02929303",
      "title": "Expanded Access of Omegaven IV Fat Emulsion to Infants and Children With PNALD",
      "overall_status": "APPROVED_FOR_MARKETING",
      "study_type": "EXPANDED_ACCESS",
      "phases": [],
      "conditions": [
        "Total Parenteral Nutrition-induced Cholestasis"
      ],
      "interventions": [
        {
          "name": "Omegaven IV lipid emulsion",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Wake Forest University Health Sciences",
      "sponsor_class": "OTHER",
      "healthy_volunteers": null,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": "17 Years",
        "sex": "ALL",
        "summary": "Up to 17 Years"
      },
      "enrollment_count": null,
      "start_date": null,
      "completion_date": null,
      "has_results": false,
      "last_update_posted_date": "2025-10-01",
      "last_synced_at": "2026-06-10T06:24:55.665Z",
      "location_count": 1,
      "location_summary": "Park Ridge, Illinois",
      "locations": [
        {
          "city": "Park Ridge",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02929303"
    },
    {
      "nct_id": "NCT02534077",
      "title": "Intravenous Fat Emulsion Comprised of Fish Oil in the Treatment of Parenteral Nutrition Induced Liver Injury in Infants",
      "overall_status": "APPROVED_FOR_MARKETING",
      "study_type": "EXPANDED_ACCESS",
      "phases": [],
      "conditions": [
        "Total Parenteral Nutrition-induced Cholestasis"
      ],
      "interventions": [
        {
          "name": "Omegaven",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Omegaven",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DIETARY_SUPPLEMENT",
        "DRUG"
      ],
      "sponsor": "Pediatrix",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "14 Days",
        "maximum_age": "2 Years",
        "sex": "ALL",
        "summary": "14 Days to 2 Years"
      },
      "enrollment_count": null,
      "start_date": null,
      "completion_date": null,
      "has_results": false,
      "last_update_posted_date": "2024-07-26",
      "last_synced_at": "2026-06-10T06:24:55.665Z",
      "location_count": 1,
      "location_summary": "San Antonio, Texas",
      "locations": [
        {
          "city": "San Antonio",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02534077"
    },
    {
      "nct_id": "NCT02780193",
      "title": "Intravenous Fish Oils in the Treatment of Parenteral Nutrition Liver Injury",
      "overall_status": "APPROVED_FOR_MARKETING",
      "study_type": "EXPANDED_ACCESS",
      "phases": [],
      "conditions": [
        "Cholestasis",
        "Total Parenteral Nutrition-induced Cholestasis"
      ],
      "interventions": [
        {
          "name": "Omegaven",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Rush University Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": null,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": "18 Years",
        "sex": "ALL",
        "summary": "Up to 18 Years"
      },
      "enrollment_count": null,
      "start_date": null,
      "completion_date": null,
      "has_results": false,
      "last_update_posted_date": "2019-04-08",
      "last_synced_at": "2026-06-10T06:24:55.665Z",
      "location_count": 1,
      "location_summary": "Chicago, Illinois",
      "locations": [
        {
          "city": "Chicago",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02780193"
    },
    {
      "nct_id": "NCT04555044",
      "title": "Pediatric Study to Evaluate Risk of Developing Essential Fatty Acid Deficiency When Receiving Clinolipid or Standard-of-Care Lipid Emulsion (Part A)",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Essential Fatty Acid Deficiency (EFAD)"
      ],
      "interventions": [
        {
          "name": "Clinolipid",
          "type": "DRUG"
        },
        {
          "name": "Intralipid",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Baxter Healthcare Corporation",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "0 Years",
        "maximum_age": "17 Years",
        "sex": "ALL",
        "summary": "0 Years to 17 Years"
      },
      "enrollment_count": 101,
      "start_date": "2021-01-22",
      "completion_date": "2022-11-16",
      "has_results": true,
      "last_update_posted_date": "2023-12-27",
      "last_synced_at": "2026-06-10T06:24:55.665Z",
      "location_count": 9,
      "location_summary": "Mobile, Alabama • New Haven, Connecticut • Orlando, Florida + 6 more",
      "locations": [
        {
          "city": "Mobile",
          "state": "Alabama"
        },
        {
          "city": "New Haven",
          "state": "Connecticut"
        },
        {
          "city": "Orlando",
          "state": "Florida"
        },
        {
          "city": "Boston",
          "state": "Massachusetts"
        },
        {
          "city": "Jackson",
          "state": "Mississippi"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04555044"
    },
    {
      "nct_id": "NCT00910104",
      "title": "Cholestasis Reversal: Efficacy of IV Fish Oil",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2",
        "PHASE3"
      ],
      "conditions": [
        "Parenteral Nutrition Associated Liver Disease",
        "Short Bowel Syndrome",
        "Gastrointestinal Disease"
      ],
      "interventions": [
        {
          "name": "Omegaven®",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Mark Puder",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": "17 Years",
        "sex": "ALL",
        "summary": "Up to 17 Years"
      },
      "enrollment_count": 91,
      "start_date": "2006-08",
      "completion_date": "2019-01-23",
      "has_results": true,
      "last_update_posted_date": "2024-09-19",
      "last_synced_at": "2026-06-10T06:24:55.665Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00910104"
    },
    {
      "nct_id": "NCT00512629",
      "title": "Cholestasis Prevention: Efficacy of IV Fish Oil",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Cholestasis",
        "Parenteral Nutrition"
      ],
      "interventions": [
        {
          "name": "Omegaven",
          "type": "DRUG"
        },
        {
          "name": "Intralipid",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Boston Children's Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": "3 Months",
        "sex": "ALL",
        "summary": "Up to 3 Months"
      },
      "enrollment_count": 19,
      "start_date": "2007-07",
      "completion_date": "2011-12",
      "has_results": false,
      "last_update_posted_date": "2020-12-03",
      "last_synced_at": "2026-06-10T06:24:55.665Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00512629"
    }
  ]
}