{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Chronic+Ankle+Instability&page=2",
    "query": {
      "condition": "Chronic Ankle Instability",
      "page": 2
    },
    "page_size": 10
  },
  "pagination": {
    "page": 2,
    "page_size": 10,
    "total_count": 10,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Chronic+Ankle+Instability&page=1&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-06-11T09:09:41.346Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT07237581",
      "title": "Cognitive Behavioral Based Physical Therapy for Patients With Chronic Ankle Instability",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Ankle Sprains",
        "Chronic Ankle Instability"
      ],
      "interventions": [
        {
          "name": "CBPT/HEP",
          "type": "BEHAVIORAL"
        },
        {
          "name": "HEP Only",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Creighton University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "19 Years",
        "maximum_age": "35 Years",
        "sex": "ALL",
        "summary": "19 Years to 35 Years"
      },
      "enrollment_count": 36,
      "start_date": "2023-04-14",
      "completion_date": "2024-07-01",
      "has_results": false,
      "last_update_posted_date": "2025-11-20",
      "last_synced_at": "2026-06-11T09:09:41.346Z",
      "location_count": 1,
      "location_summary": "Omaha, Nebraska",
      "locations": [
        {
          "city": "Omaha",
          "state": "Nebraska"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07237581"
    },
    {
      "nct_id": "NCT00601471",
      "title": "Effects of Proximal and Distal Tibiofibular Joint Manipulation on Lower Extremity Muscle Activation, Ankle Range of Motion, and Functional Outcome Scores in Individuals With Chronic Ankle Instability",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Ankle Sprain",
        "Ankle Injuries",
        "Sprain"
      ],
      "interventions": [
        {
          "name": "proximal tibiofibular manipulation",
          "type": "OTHER"
        },
        {
          "name": "distal tibiofibular manipulation",
          "type": "OTHER"
        },
        {
          "name": "no intervention",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of Virginia",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "50 Years",
        "sex": "ALL",
        "summary": "18 Years to 50 Years"
      },
      "enrollment_count": 61,
      "start_date": "2007-04",
      "completion_date": "2010-01",
      "has_results": false,
      "last_update_posted_date": "2010-06-24",
      "last_synced_at": "2026-06-11T09:09:41.346Z",
      "location_count": 1,
      "location_summary": "Charlottesville, Virginia",
      "locations": [
        {
          "city": "Charlottesville",
          "state": "Virginia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00601471"
    },
    {
      "nct_id": "NCT06401681",
      "title": "Cross-Education for Chronic Ankle Instability",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Balance Training Group",
        "Control Group"
      ],
      "interventions": [
        {
          "name": "Balance training",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Old Dominion University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "40 Years",
        "sex": "ALL",
        "summary": "18 Years to 40 Years"
      },
      "enrollment_count": 30,
      "start_date": "2019-05-08",
      "completion_date": "2022-05-24",
      "has_results": false,
      "last_update_posted_date": "2024-05-07",
      "last_synced_at": "2026-06-11T09:09:41.346Z",
      "location_count": 1,
      "location_summary": "Norfolk, Virginia",
      "locations": [
        {
          "city": "Norfolk",
          "state": "Virginia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06401681"
    },
    {
      "nct_id": "NCT02682654",
      "title": "A Multi-Site Evaluation of the Pain Relief, Support, Fit and Comfort From Use of a Custom Knee or Ankle Brace in Persons Suffering From Chronic Ankle or Knee Pain and Instability",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Joint Instability"
      ],
      "interventions": [
        {
          "name": "Dr. Scholl's Prototype Ankle Brace",
          "type": "DEVICE"
        },
        {
          "name": "Dr. Scholl's Prototype Knee Brace",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Bayer",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 183,
      "start_date": "2016-02-05",
      "completion_date": "2016-04-26",
      "has_results": false,
      "last_update_posted_date": "2018-12-12",
      "last_synced_at": "2026-06-11T09:09:41.346Z",
      "location_count": 2,
      "location_summary": "Colorado Springs, Colorado • Richardson, Texas",
      "locations": [
        {
          "city": "Colorado Springs",
          "state": "Colorado"
        },
        {
          "city": "Richardson",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02682654"
    },
    {
      "nct_id": "NCT03418051",
      "title": "Mechanisms of Manual Therapies in CAI Patients",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Ankle Inversion Sprain",
        "Chronic Instability of Joint"
      ],
      "interventions": [
        {
          "name": "Joint Mobilization",
          "type": "OTHER"
        },
        {
          "name": "Massage",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of North Carolina, Chapel Hill",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "35 Years",
        "sex": "ALL",
        "summary": "18 Years to 35 Years"
      },
      "enrollment_count": 60,
      "start_date": "2018-09-01",
      "completion_date": "2020-10-09",
      "has_results": true,
      "last_update_posted_date": "2021-08-27",
      "last_synced_at": "2026-06-11T09:09:41.346Z",
      "location_count": 1,
      "location_summary": "Chapel Hill, North Carolina",
      "locations": [
        {
          "city": "Chapel Hill",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03418051"
    },
    {
      "nct_id": "NCT04999904",
      "title": "A Proprioceptive Training Program Using an Uneven Terrain Treadmill for Patients With Ankle Instability",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Instability; Ankle (Ligaments) (Old Injury)",
        "Sprain of Ankle"
      ],
      "interventions": [
        {
          "name": "Uneven Treadmill Intervention",
          "type": "OTHER"
        },
        {
          "name": "Standard of Care Physical Therapy",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Henry M. Jackson Foundation for the Advancement of Military Medicine",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "49 Years",
        "sex": "ALL",
        "summary": "18 Years to 49 Years"
      },
      "enrollment_count": 312,
      "start_date": "2021-11-23",
      "completion_date": "2026-09-30",
      "has_results": false,
      "last_update_posted_date": "2025-07-18",
      "last_synced_at": "2026-06-11T09:09:41.346Z",
      "location_count": 2,
      "location_summary": "Oceanside, California • San Diego, California",
      "locations": [
        {
          "city": "Oceanside",
          "state": "California"
        },
        {
          "city": "San Diego",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04999904"
    },
    {
      "nct_id": "NCT01541657",
      "title": "Sensory-Targeted Ankle Rehabilitation Strategies (STARS)",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Chronic Ankle Instability"
      ],
      "interventions": [
        {
          "name": "Ankle Joint Mobilization",
          "type": "OTHER"
        },
        {
          "name": "Foot Massage",
          "type": "OTHER"
        },
        {
          "name": "Calf Stretching",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Joel Thompson",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "45 Years",
        "sex": "ALL",
        "summary": "18 Years to 45 Years"
      },
      "enrollment_count": 80,
      "start_date": "2011-12",
      "completion_date": "2014-04",
      "has_results": false,
      "last_update_posted_date": "2018-01-26",
      "last_synced_at": "2026-06-11T09:09:41.346Z",
      "location_count": 2,
      "location_summary": "Ithaca, New York • Charlotte, North Carolina",
      "locations": [
        {
          "city": "Ithaca",
          "state": "New York"
        },
        {
          "city": "Charlotte",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01541657"
    },
    {
      "nct_id": "NCT07084220",
      "title": "The Effect of Cognitive Tasks on Single Limb Balance",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Chronic Ankle Instability, CAI",
        "Healthy Participants"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Towson University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "40 Years",
        "sex": "ALL",
        "summary": "18 Years to 40 Years"
      },
      "enrollment_count": 39,
      "start_date": "2019-08-18",
      "completion_date": "2020-07-31",
      "has_results": false,
      "last_update_posted_date": "2025-07-24",
      "last_synced_at": "2026-06-11T09:09:41.346Z",
      "location_count": 1,
      "location_summary": "Towson, Maryland",
      "locations": [
        {
          "city": "Towson",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07084220"
    },
    {
      "nct_id": "NCT06868316",
      "title": "Auditory Biofeedback Gait Training Individuals With Chronic Ankle Instability",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Ankle Sprains",
        "Ankle Injuries and Disorders"
      ],
      "interventions": [
        {
          "name": "Walking",
          "type": "OTHER"
        },
        {
          "name": "Rucking",
          "type": "OTHER"
        },
        {
          "name": "Running",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of Kentucky",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "45 Years",
        "sex": "ALL",
        "summary": "18 Years to 45 Years"
      },
      "enrollment_count": 100,
      "start_date": "2025-05-27",
      "completion_date": "2028-09",
      "has_results": false,
      "last_update_posted_date": "2025-10-07",
      "last_synced_at": "2026-06-11T09:09:41.346Z",
      "location_count": 2,
      "location_summary": "Lexington, Kentucky • Charlotte, North Carolina",
      "locations": [
        {
          "city": "Lexington",
          "state": "Kentucky"
        },
        {
          "city": "Charlotte",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06868316"
    },
    {
      "nct_id": "NCT06390072",
      "title": "Project Hypnos: The Impact of a Brief Hypnosis Intervention on Single-limb Dynamic Balance in People With Chronic Ankle Instability",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Ankle Sprains",
        "Motor Coordination or Function; Developmental Disorder"
      ],
      "interventions": [
        {
          "name": "Self-Hypnosis",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Ankle Education",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Ohio University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 24,
      "start_date": "2023-09-25",
      "completion_date": "2023-11-27",
      "has_results": false,
      "last_update_posted_date": "2024-04-29",
      "last_synced_at": "2026-06-11T09:09:41.346Z",
      "location_count": 1,
      "location_summary": "Athens, Ohio",
      "locations": [
        {
          "city": "Athens",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06390072"
    }
  ]
}