{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Chronic+Cough",
    "query": {
      "condition": "Chronic Cough"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 67,
    "total_pages": 7,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Chronic+Cough&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-06-27T04:58:03.531Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT05660850",
      "title": "A Study To Evaluate The Efficacy, Safety, Pharmacokinetics, And Pharmacodynamic Effects Of GDC-6599 In Patients With Chronic Cough",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Chronic Refractory Cough (CRC) With Non-atopic Asthma",
        "CRC With Atopic Asthma",
        "Unexplained Chronic Cough",
        "CRC With Chronic Obstructive Pulmonary Disease",
        "CRC With Chronic Obstructive Pulmonary Disease With Chronic Bronchitis"
      ],
      "interventions": [
        {
          "name": "GDC-6599",
          "type": "DRUG"
        },
        {
          "name": "GDC-6599-matching placebo",
          "type": "OTHER"
        },
        {
          "name": "Mannitol",
          "type": "DIAGNOSTIC_TEST"
        }
      ],
      "intervention_types": [
        "DRUG",
        "OTHER",
        "DIAGNOSTIC_TEST"
      ],
      "sponsor": "Genentech, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "18 Years to 80 Years"
      },
      "enrollment_count": 49,
      "start_date": "2023-03-22",
      "completion_date": "2024-10-20",
      "has_results": true,
      "last_update_posted_date": "2025-12-16",
      "last_synced_at": "2026-06-27T04:58:03.531Z",
      "location_count": 8,
      "location_summary": "Los Angeles, California • Northridge, California • Coral Gables, Florida + 5 more",
      "locations": [
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Northridge",
          "state": "California"
        },
        {
          "city": "Coral Gables",
          "state": "Florida"
        },
        {
          "city": "Rochester",
          "state": "Minnesota"
        },
        {
          "city": "DuBois",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05660850"
    },
    {
      "nct_id": "NCT05392192",
      "title": "A Clinical Trial to Evaluate the Safety and Efficacy in Subjects With Chronic Cough",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Chronic Cough"
      ],
      "interventions": [
        {
          "name": "ADX-629",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Aldeyra Therapeutics, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "18 Years to 80 Years"
      },
      "enrollment_count": 51,
      "start_date": "2022-04-07",
      "completion_date": "2023-04-13",
      "has_results": true,
      "last_update_posted_date": "2025-02-28",
      "last_synced_at": "2026-06-27T04:58:03.531Z",
      "location_count": 14,
      "location_summary": "San Diego, California • San Jose, California • Hollywood, Florida + 11 more",
      "locations": [
        {
          "city": "San Diego",
          "state": "California"
        },
        {
          "city": "San Jose",
          "state": "California"
        },
        {
          "city": "Hollywood",
          "state": "Florida"
        },
        {
          "city": "Loxahatchee Groves",
          "state": "Florida"
        },
        {
          "city": "Winter Park",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05392192"
    },
    {
      "nct_id": "NCT06634823",
      "title": "Efficacy of Intramuscular Steroid Injection for Chronic Cough.",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "EARLY_PHASE1"
      ],
      "conditions": [
        "Chronic Cough (CC)",
        "Laryngeal Disease",
        "Coughing"
      ],
      "interventions": [
        {
          "name": "Triamcinolone Acetonide Injectable Suspension",
          "type": "DRUG"
        },
        {
          "name": "Saline injection",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Medical University of South Carolina",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 40,
      "start_date": "2024-12-02",
      "completion_date": "2026-06-30",
      "has_results": false,
      "last_update_posted_date": "2025-07-14",
      "last_synced_at": "2026-06-27T04:58:03.531Z",
      "location_count": 1,
      "location_summary": "Charleston, South Carolina",
      "locations": [
        {
          "city": "Charleston",
          "state": "South Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06634823"
    },
    {
      "nct_id": "NCT05628740",
      "title": "Placebo-controlled, Single and Multiple Dose Study in Healthy Volunteers and Refractory Chronic Cough Patients to Assess the Safety, Tolerability, and Pharmacokinetics of Two Formulations of NTX-1175",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Refractory Chronic Cough"
      ],
      "interventions": [
        {
          "name": "3 mg NOC-100 (via nebulizer)",
          "type": "DRUG"
        },
        {
          "name": "1 mg NOC-110 (via DPI) [1x 1 mg capsule]",
          "type": "DRUG"
        },
        {
          "name": "3 mg NOC-110 (via DPI)",
          "type": "DRUG"
        },
        {
          "name": "Placebo (via DPI)",
          "type": "DRUG"
        },
        {
          "name": "6 mg NOC-110 (via DPI)",
          "type": "DRUG"
        },
        {
          "name": "Placebo (via DPI) [2x Placebo capsules]",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Nocion Therapeutics",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "85 Years",
        "sex": "ALL",
        "summary": "18 Years to 85 Years"
      },
      "enrollment_count": 24,
      "start_date": "2022-02-07",
      "completion_date": "2022-10-25",
      "has_results": false,
      "last_update_posted_date": "2023-03-30",
      "last_synced_at": "2026-06-27T04:58:03.531Z",
      "location_count": 3,
      "location_summary": "Phoenix, Arizona • Leesburg, Florida • Winter Park, Florida",
      "locations": [
        {
          "city": "Phoenix",
          "state": "Arizona"
        },
        {
          "city": "Leesburg",
          "state": "Florida"
        },
        {
          "city": "Winter Park",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05628740"
    },
    {
      "nct_id": "NCT03282591",
      "title": "Study of the Efficacy, Safety, and Tolerability of Serlopitant for the Treatment of Refractory Chronic Cough",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Refractory Chronic Cough"
      ],
      "interventions": [
        {
          "name": "5 mg Serlopitant Tablets",
          "type": "DRUG"
        },
        {
          "name": "Matching Placebo Tablets",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Vyne Therapeutics Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "18 Years to 80 Years"
      },
      "enrollment_count": 185,
      "start_date": "2017-10-03",
      "completion_date": "2018-09-06",
      "has_results": true,
      "last_update_posted_date": "2021-05-20",
      "last_synced_at": "2026-06-27T04:58:03.531Z",
      "location_count": 29,
      "location_summary": "Los Angeles, California • Mission Viejo, California • San Diego, California + 24 more",
      "locations": [
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Mission Viejo",
          "state": "California"
        },
        {
          "city": "San Diego",
          "state": "California"
        },
        {
          "city": "San Jose",
          "state": "California"
        },
        {
          "city": "Stockton",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03282591"
    },
    {
      "nct_id": "NCT02662907",
      "title": "Cough, Expiratory Training, and Chronic Aspiration After Head and Neck Radiotherapy",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Head and Neck Cancer"
      ],
      "interventions": [
        {
          "name": "Barium Swallow",
          "type": "PROCEDURE"
        },
        {
          "name": "Questionnaires",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Expiratory Muscle Strength Training (EMST) Device",
          "type": "DEVICE"
        },
        {
          "name": "Digital Manometer",
          "type": "DEVICE"
        },
        {
          "name": "Neurocognitive Exams",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Barium",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "PROCEDURE",
        "BEHAVIORAL",
        "DEVICE",
        "DRUG"
      ],
      "sponsor": "M.D. Anderson Cancer Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 175,
      "start_date": "2016-02-01",
      "completion_date": "2027-02-02",
      "has_results": false,
      "last_update_posted_date": "2026-04-16",
      "last_synced_at": "2026-06-27T04:58:03.531Z",
      "location_count": 1,
      "location_summary": "Houston, Texas",
      "locations": [
        {
          "city": "Houston",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02662907"
    },
    {
      "nct_id": "NCT02825043",
      "title": "HFNC Effect on BCSS in Patients With COPD",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Chronic Obstructive Pulmonary Disease"
      ],
      "interventions": [
        {
          "name": "High-Flow Nasal Cannula",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "University of Oklahoma",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "35 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "35 Years to 80 Years"
      },
      "enrollment_count": 6,
      "start_date": "2016-02",
      "completion_date": "2018-11-21",
      "has_results": true,
      "last_update_posted_date": "2020-06-29",
      "last_synced_at": "2026-06-27T04:58:03.531Z",
      "location_count": 1,
      "location_summary": "Oklahoma City, Oklahoma",
      "locations": [
        {
          "city": "Oklahoma City",
          "state": "Oklahoma"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02825043"
    },
    {
      "nct_id": "NCT07070895",
      "title": "Cough Management Wellness App for Refractory or Unexplained Chronic Cough",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Refractory Chronic Cough",
        "Unexplained Chronic Cough",
        "Cough Hypersensitivity"
      ],
      "interventions": [
        {
          "name": "Cough Management",
          "type": "BEHAVIORAL"
        },
        {
          "name": "CoughMonitor Suite",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL",
        "DEVICE"
      ],
      "sponsor": "Hyfe Inc",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "21 Years and older"
      },
      "enrollment_count": 20,
      "start_date": "2025-03-27",
      "completion_date": "2025-09",
      "has_results": false,
      "last_update_posted_date": "2025-09-11",
      "last_synced_at": "2026-06-27T04:58:03.531Z",
      "location_count": 1,
      "location_summary": "Wilmington, Delaware",
      "locations": [
        {
          "city": "Wilmington",
          "state": "Delaware"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07070895"
    },
    {
      "nct_id": "NCT03172130",
      "title": "Sham CPAP vs. Straight CPAP for Chronic Cough",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Chronic Cough",
        "OSA"
      ],
      "interventions": [
        {
          "name": "Straight CPAP",
          "type": "DEVICE"
        },
        {
          "name": "Sham CPAP",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Krishna M. Sundar",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "18 Years to 80 Years"
      },
      "enrollment_count": 22,
      "start_date": "2014-10-13",
      "completion_date": "2019-11-25",
      "has_results": true,
      "last_update_posted_date": "2020-06-18",
      "last_synced_at": "2026-06-27T04:58:03.531Z",
      "location_count": 1,
      "location_summary": "Salt Lake City, Utah",
      "locations": [
        {
          "city": "Salt Lake City",
          "state": "Utah"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03172130"
    },
    {
      "nct_id": "NCT05226299",
      "title": "Cough Desensitization Therapy: Pilot 2",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Cough"
      ],
      "interventions": [
        {
          "name": "Supra-threshold and progressive doses of diluted capsaicin via a dosimeter-controlled nebulizer",
          "type": "BIOLOGICAL"
        },
        {
          "name": "Saline",
          "type": "BIOLOGICAL"
        }
      ],
      "intervention_types": [
        "BIOLOGICAL"
      ],
      "sponsor": "University of Montana",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "99 Years",
        "sex": "ALL",
        "summary": "18 Years to 99 Years"
      },
      "enrollment_count": 22,
      "start_date": "2021-05-01",
      "completion_date": "2022-08-30",
      "has_results": false,
      "last_update_posted_date": "2022-11-03",
      "last_synced_at": "2026-06-27T04:58:03.531Z",
      "location_count": 1,
      "location_summary": "Missoula, Montana",
      "locations": [
        {
          "city": "Missoula",
          "state": "Montana"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05226299"
    }
  ]
}