{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Chronic+Critical+Illness",
    "query": {
      "condition": "Chronic Critical Illness"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 17,
    "total_pages": 2,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Chronic+Critical+Illness&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-05-22T08:46:03.216Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT01230099",
      "title": "Informing Decisions in Chronic Critical Illness: A Randomized Control Trial (RCT)",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Chronic Critical Illness",
        "Prolonged Mechanical Ventilation"
      ],
      "interventions": [
        {
          "name": "Supportive Information Team Group",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Icahn School of Medicine at Mount Sinai",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "21 Years and older"
      },
      "enrollment_count": 622,
      "start_date": "2010-10",
      "completion_date": "2014-10",
      "has_results": false,
      "last_update_posted_date": "2015-10-29",
      "last_synced_at": "2026-05-22T08:46:03.216Z",
      "location_count": 4,
      "location_summary": "New York, New York • Chapel Hill, North Carolina • Durham, North Carolina",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        },
        {
          "city": "Chapel Hill",
          "state": "North Carolina"
        },
        {
          "city": "Durham",
          "state": "North Carolina"
        },
        {
          "city": "Durham",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01230099"
    },
    {
      "nct_id": "NCT02873000",
      "title": "Incentive Spirometry in Non-critically Ill Hospitalized Patients With Acute Respiratory Failure",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Pulmonary Complication",
        "Dyspnea",
        "Pneumonia",
        "COPD",
        "CHF",
        "Atelectasis",
        "PE"
      ],
      "interventions": [
        {
          "name": "Incentive Spirometry",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Jewish Hospital, Cincinnati, Ohio",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "65 Years",
        "maximum_age": "99 Years",
        "sex": "ALL",
        "summary": "65 Years to 99 Years"
      },
      "enrollment_count": 100,
      "start_date": "2017-04",
      "completion_date": "2017-06",
      "has_results": false,
      "last_update_posted_date": "2017-04-18",
      "last_synced_at": "2026-05-22T08:46:03.216Z",
      "location_count": 1,
      "location_summary": "Cincinnati, Ohio",
      "locations": [
        {
          "city": "Cincinnati",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02873000"
    },
    {
      "nct_id": "NCT01751061",
      "title": "Improving Decision Making for Patients With Prolonged Mechanical Ventilation",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Surrogate Decision Makers",
        "Prolonged Mechanical Ventilation"
      ],
      "interventions": [
        {
          "name": "Decision aid",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Usual care",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL",
        "OTHER"
      ],
      "sponsor": "Duke University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 416,
      "start_date": "2013-01",
      "completion_date": "2017-01-06",
      "has_results": true,
      "last_update_posted_date": "2019-05-02",
      "last_synced_at": "2026-05-22T08:46:03.216Z",
      "location_count": 4,
      "location_summary": "Chapel Hill, North Carolina • Durham, North Carolina • Pittsburgh, Pennsylvania + 1 more",
      "locations": [
        {
          "city": "Chapel Hill",
          "state": "North Carolina"
        },
        {
          "city": "Durham",
          "state": "North Carolina"
        },
        {
          "city": "Pittsburgh",
          "state": "Pennsylvania"
        },
        {
          "city": "Seattle",
          "state": "Washington"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01751061"
    },
    {
      "nct_id": "NCT03159208",
      "title": "Prediction of Functional Outcomes From Chronic Critical Illness",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Chronic Critical Illness",
        "Prolonged Mechanical Ventilation"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "University of North Carolina, Chapel Hill",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 589,
      "start_date": "2017-04-17",
      "completion_date": "2021-09-05",
      "has_results": false,
      "last_update_posted_date": "2021-10-28",
      "last_synced_at": "2026-05-22T08:46:03.216Z",
      "location_count": 6,
      "location_summary": "Denver, Colorado • The Bronx, New York • Chapel Hill, North Carolina + 3 more",
      "locations": [
        {
          "city": "Denver",
          "state": "Colorado"
        },
        {
          "city": "The Bronx",
          "state": "New York"
        },
        {
          "city": "Chapel Hill",
          "state": "North Carolina"
        },
        {
          "city": "Durham",
          "state": "North Carolina"
        },
        {
          "city": "Pittsburgh",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03159208"
    },
    {
      "nct_id": "NCT00484445",
      "title": "Transfer to Another Health Care Facility Following Critical Illness",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Transfer to a Health Care Facility After Critical Illness"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "University of Chicago",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 548,
      "start_date": "2003-01",
      "completion_date": "2003-01",
      "has_results": false,
      "last_update_posted_date": "2013-09-05",
      "last_synced_at": "2026-05-22T08:46:03.216Z",
      "location_count": 1,
      "location_summary": "Chicago, Illinois",
      "locations": [
        {
          "city": "Chicago",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00484445"
    },
    {
      "nct_id": "NCT02467023",
      "title": "Project 4B: Lower Extremity Strength Training in ICU Patients",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Sepsis"
      ],
      "interventions": [
        {
          "name": "Muscle stimulation with Niveus medical stimulator",
          "type": "DEVICE"
        },
        {
          "name": "measurement of maximal isometric twitch strength",
          "type": "DEVICE"
        },
        {
          "name": "Muscle Biopsy",
          "type": "PROCEDURE"
        },
        {
          "name": "Muscle Biopsy Medication: Lidocaine",
          "type": "DRUG"
        },
        {
          "name": "Muscle Biopsy Medication: Versed",
          "type": "DRUG"
        },
        {
          "name": "Muscle Biopsy Medication: Fentanyl",
          "type": "DRUG"
        },
        {
          "name": "Blood and Urine Sampling",
          "type": "OTHER"
        },
        {
          "name": "ineffective muscle stimulation",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "PROCEDURE",
        "DRUG",
        "OTHER"
      ],
      "sponsor": "University of Florida",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 5,
      "start_date": "2015-09",
      "completion_date": "2016-07-15",
      "has_results": false,
      "last_update_posted_date": "2018-01-19",
      "last_synced_at": "2026-05-22T08:46:03.216Z",
      "location_count": 1,
      "location_summary": "Gainesville, Florida",
      "locations": [
        {
          "city": "Gainesville",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02467023"
    },
    {
      "nct_id": "NCT03195127",
      "title": "Development of a Rehabilitation Strengthening and Mobility Program for Ventilator Dependent Older Patients",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Respiration, Artificial",
        "Critical Illness",
        "Chronic Disease",
        "Exercise Therapy",
        "Rehabilitation",
        "Physical Therapy Modalities"
      ],
      "interventions": [
        {
          "name": "multimodal physical therapy",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of Maryland, Baltimore",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "20 Years",
        "maximum_age": "100 Years",
        "sex": "ALL",
        "summary": "20 Years to 100 Years"
      },
      "enrollment_count": 33,
      "start_date": "2011-06-28",
      "completion_date": "2017-02-01",
      "has_results": true,
      "last_update_posted_date": "2023-05-10",
      "last_synced_at": "2026-05-22T08:46:03.216Z",
      "location_count": 1,
      "location_summary": "Baltimore, Maryland",
      "locations": [
        {
          "city": "Baltimore",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03195127"
    },
    {
      "nct_id": "NCT06606119",
      "title": "The Role of Brain-Bone Marrow-Gut Interaction Following Major Trauma",
      "overall_status": "RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Trauma Injury",
        "Trauma",
        "Critical Illness",
        "Microbiome",
        "Chronic Anemia",
        "Acute Blood Loss Anemia"
      ],
      "interventions": [
        {
          "name": "Data and tissue collection",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of Florida",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "100 Years",
        "sex": "ALL",
        "summary": "18 Years to 100 Years"
      },
      "enrollment_count": 275,
      "start_date": "2025-01-24",
      "completion_date": "2028-10-01",
      "has_results": false,
      "last_update_posted_date": "2026-02-06",
      "last_synced_at": "2026-05-22T08:46:03.216Z",
      "location_count": 3,
      "location_summary": "Gainesville, Florida",
      "locations": [
        {
          "city": "Gainesville",
          "state": "Florida"
        },
        {
          "city": "Gainesville",
          "state": "Florida"
        },
        {
          "city": "Gainesville",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06606119"
    },
    {
      "nct_id": "NCT00685893",
      "title": "Integrating Palliative and Critical Care (IPACC) Study",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Any Disease Causing Death in the ICU or Within 24 Hours of Discharge From the ICU"
      ],
      "interventions": [
        {
          "name": "Education",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Local Champions",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Institution Feedback",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Academic Detailing",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Institutional Forms",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of Washington",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 3498,
      "start_date": "2003-06",
      "completion_date": "2010-10",
      "has_results": false,
      "last_update_posted_date": "2013-06-27",
      "last_synced_at": "2026-05-22T08:46:03.216Z",
      "location_count": 15,
      "location_summary": "Bellevue, Washington • Bremerton, Washington • Burien, Washington + 5 more",
      "locations": [
        {
          "city": "Bellevue",
          "state": "Washington"
        },
        {
          "city": "Bremerton",
          "state": "Washington"
        },
        {
          "city": "Burien",
          "state": "Washington"
        },
        {
          "city": "Edmonds",
          "state": "Washington"
        },
        {
          "city": "Kirkland",
          "state": "Washington"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00685893"
    },
    {
      "nct_id": "NCT02858778",
      "title": "Timing of Acute Palliative Care Consultation in Critically Ill Patients",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Multiple Organ Failure",
        "End Stage Cardiac Failure",
        "End Stage Chronic Obstructive Airways Disease",
        "Chronic Kidney Disease Stage 5",
        "Hepatic Encephalopathy",
        "Sepsis",
        "Dementia",
        "Multiple Sclerosis",
        "Parkinson's Disease",
        "In-Hospital Cardiac Arrest",
        "Solid Organ Cancer"
      ],
      "interventions": [
        {
          "name": "Early order of palliative care consultation",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Wayne State University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "65 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "65 Years and older"
      },
      "enrollment_count": 120,
      "start_date": "2016-06",
      "completion_date": null,
      "has_results": false,
      "last_update_posted_date": "2016-08-08",
      "last_synced_at": "2026-05-22T08:46:03.216Z",
      "location_count": 2,
      "location_summary": "Detroit, Michigan",
      "locations": [
        {
          "city": "Detroit",
          "state": "Michigan"
        },
        {
          "city": "Detroit",
          "state": "Michigan"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02858778"
    }
  ]
}