{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Chronic+Exertional+Compartment+Syndrome",
    "query": {
      "condition": "Chronic Exertional Compartment Syndrome"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 7,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-06-11T01:22:47.762Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT05466539",
      "title": "Chronic Exertional Compartment Syndrome (CECS) Treated With Abobotulinumtoxin A",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Compartment Syndrome of Leg"
      ],
      "interventions": [
        {
          "name": "AbobotulinumtoxinA",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Emory University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 3,
      "start_date": "2024-04-25",
      "completion_date": "2025-08-13",
      "has_results": false,
      "last_update_posted_date": "2025-10-21",
      "last_synced_at": "2026-06-11T01:22:47.762Z",
      "location_count": 2,
      "location_summary": "Atlanta, Georgia • Brookhaven, Georgia",
      "locations": [
        {
          "city": "Atlanta",
          "state": "Georgia"
        },
        {
          "city": "Brookhaven",
          "state": "Georgia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05466539"
    },
    {
      "nct_id": "NCT03736174",
      "title": "Utilization of High Frequency Ultrasound to Diagnose Chronic Exertional Compartment Syndrome",
      "overall_status": "UNKNOWN",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Chronic Exertional Compartment Syndrome"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "University of Colorado, Denver",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "13 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "13 Years and older"
      },
      "enrollment_count": 20,
      "start_date": "2018-12-07",
      "completion_date": "2023-12",
      "has_results": false,
      "last_update_posted_date": "2023-04-25",
      "last_synced_at": "2026-06-11T01:22:47.762Z",
      "location_count": 1,
      "location_summary": "Denver, Colorado",
      "locations": [
        {
          "city": "Denver",
          "state": "Colorado"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03736174"
    },
    {
      "nct_id": "NCT03922139",
      "title": "Botox for the Treatment of Chronic Exertional Compartment Syndrome",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1",
        "PHASE2"
      ],
      "conditions": [
        "Compartment Syndrome of Leg"
      ],
      "interventions": [
        {
          "name": "OnabotulinumtoxinA Injection",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of Wisconsin, Madison",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 7,
      "start_date": "2019-10-08",
      "completion_date": "2021-12-15",
      "has_results": true,
      "last_update_posted_date": "2023-02-14",
      "last_synced_at": "2026-06-11T01:22:47.762Z",
      "location_count": 1,
      "location_summary": "Madison, Wisconsin",
      "locations": [
        {
          "city": "Madison",
          "state": "Wisconsin"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03922139"
    },
    {
      "nct_id": "NCT05006417",
      "title": "Botox for the Treatment of Recurrent Chronic Exertional Compartment Syndrome",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Compartment Syndrome of Leg"
      ],
      "interventions": [
        {
          "name": "Botox",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of Wisconsin, Madison",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 1,
      "start_date": "2022-11-23",
      "completion_date": "2022-11-23",
      "has_results": true,
      "last_update_posted_date": "2024-07-18",
      "last_synced_at": "2026-06-11T01:22:47.762Z",
      "location_count": 1,
      "location_summary": "Madison, Wisconsin",
      "locations": [
        {
          "city": "Madison",
          "state": "Wisconsin"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05006417"
    },
    {
      "nct_id": "NCT03339921",
      "title": "Botulinum for Chronic Exertional Compartment Syndrome",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2",
        "PHASE3"
      ],
      "conditions": [
        "Chronic Exertional Compartment Syndrome"
      ],
      "interventions": [
        {
          "name": "Botulinum toxin injections for chronic compartment syndrome",
          "type": "DRUG"
        },
        {
          "name": "surgical fasciotomy for chronic compartment syndrome",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "DRUG",
        "PROCEDURE"
      ],
      "sponsor": "375th Medical Group, Scott Air Force Base",
      "sponsor_class": "FED",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 3,
      "start_date": "2018-12-07",
      "completion_date": "2020-05-01",
      "has_results": true,
      "last_update_posted_date": "2024-03-05",
      "last_synced_at": "2026-06-11T01:22:47.762Z",
      "location_count": 1,
      "location_summary": "Scott Air Force Base, Illinois",
      "locations": [
        {
          "city": "Scott Air Force Base",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03339921"
    },
    {
      "nct_id": "NCT04409600",
      "title": "Comparison of Non-Surgical Treatment Options for Chronic Exertional Compartment Syndrome (CECS)",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Chronic Exertional Compartment Syndrome"
      ],
      "interventions": [
        {
          "name": "Supervised Gait Retraining",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Home Based Gait Retraining",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Saline Injection",
          "type": "DRUG"
        },
        {
          "name": "Botulinum Toxin Injection",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL",
        "DRUG"
      ],
      "sponsor": "Walter Reed National Military Medical Center",
      "sponsor_class": "FED",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "50 Years",
        "sex": "ALL",
        "summary": "18 Years to 50 Years"
      },
      "enrollment_count": 35,
      "start_date": "2020-11-05",
      "completion_date": "2024-12-06",
      "has_results": true,
      "last_update_posted_date": "2026-03-06",
      "last_synced_at": "2026-06-11T01:22:47.762Z",
      "location_count": 4,
      "location_summary": "Bethesda, Maryland • Fort Bragg, North Carolina • Killeen, Texas + 1 more",
      "locations": [
        {
          "city": "Bethesda",
          "state": "Maryland"
        },
        {
          "city": "Fort Bragg",
          "state": "North Carolina"
        },
        {
          "city": "Killeen",
          "state": "Texas"
        },
        {
          "city": "Fort Belvoir",
          "state": "Virginia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04409600"
    },
    {
      "nct_id": "NCT05247541",
      "title": "Diagnosing Compartment Syndrome With SHAPE vs Elastography",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2",
        "PHASE3"
      ],
      "conditions": [
        "Chronic Exertional Compartment Syndrome"
      ],
      "interventions": [
        {
          "name": "Definity",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Thomas Jefferson University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 15,
      "start_date": "2020-07-01",
      "completion_date": "2023-12-01",
      "has_results": false,
      "last_update_posted_date": "2023-12-12",
      "last_synced_at": "2026-06-11T01:22:47.762Z",
      "location_count": 1,
      "location_summary": "Philadelphia, Pennsylvania",
      "locations": [
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05247541"
    }
  ]
}