{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Chronic+Fatigue+Symptoms&page=2",
    "query": {
      "condition": "Chronic Fatigue Symptoms",
      "page": 2
    },
    "page_size": 10
  },
  "pagination": {
    "page": 2,
    "page_size": 10,
    "total_count": 10,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Chronic+Fatigue+Symptoms&page=1&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-06-07T16:02:47.996Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT05167227",
      "title": "Does a Technology Enabled Multi-disciplinary Team-based Care Model for the Management of Long COVID and Other Fatiguing Illnesses Improve Clinical Care of Patients and Represent a Sustainable Approach Within a Federally Qualified Health Center?",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "SARS-CoV-2 Acute Respiratory Disease",
        "Myalgic Encephalomyelitis",
        "Chronic Fatigue Syndrome",
        "Post-acute Sequelae of SARS-COV-2 Infection",
        "Post COVID-19 Condition"
      ],
      "interventions": [
        {
          "name": "Extension for Community Healthcare Outcomes",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Family Health Centers of San Diego",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 20,
      "start_date": "2021-11-30",
      "completion_date": "2025-11-28",
      "has_results": false,
      "last_update_posted_date": "2025-08-06",
      "last_synced_at": "2026-06-07T16:02:47.996Z",
      "location_count": 1,
      "location_summary": "San Diego, California",
      "locations": [
        {
          "city": "San Diego",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05167227"
    },
    {
      "nct_id": "NCT00956475",
      "title": "Quality of Life in Younger Leukemia and Lymphoma Survivors",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Anxiety Disorder",
        "Cancer Survivor",
        "Fatigue",
        "Leukemia",
        "Long-term Effects Secondary to Cancer Therapy in Adults",
        "Lymphoma",
        "Lymphoproliferative Disorder",
        "Pain",
        "Psychosocial Effects of Cancer and Its Treatment",
        "Small Intestine Cancer"
      ],
      "interventions": [
        {
          "name": "telephone-based intervention",
          "type": "BEHAVIORAL"
        },
        {
          "name": "questionnaire administration",
          "type": "OTHER"
        },
        {
          "name": "assessment of therapy complications",
          "type": "PROCEDURE"
        },
        {
          "name": "fatigue assessment and management",
          "type": "PROCEDURE"
        },
        {
          "name": "psychosocial assessment and care",
          "type": "PROCEDURE"
        },
        {
          "name": "quality-of-life assessment",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL",
        "OTHER",
        "PROCEDURE"
      ],
      "sponsor": "Case Comprehensive Cancer Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "35 Years",
        "sex": "ALL",
        "summary": "18 Years to 35 Years"
      },
      "enrollment_count": 48,
      "start_date": "2008-10",
      "completion_date": "2011-08",
      "has_results": false,
      "last_update_posted_date": "2011-08-24",
      "last_synced_at": "2026-06-07T16:02:47.996Z",
      "location_count": 1,
      "location_summary": "Cleveland, Ohio",
      "locations": [
        {
          "city": "Cleveland",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00956475"
    },
    {
      "nct_id": "NCT06860880",
      "title": "Combating Cancer-Related Fatigue: A Personalized Supportive Care Program",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Indolent Lymphomas",
        "Lymphoma",
        "Chronic Lymphocytic Leukemia",
        "Small Lymphocytic Lymphoma",
        "Follicular Lymphoma",
        "Marginal Zone Lymphoma",
        "Lymphoplasmacytic Lymphoma",
        "Waldenstrom Macroglobulinemia",
        "Cutaneous T Cell Lymphoma"
      ],
      "interventions": [
        {
          "name": "Exercise",
          "type": "OTHER"
        },
        {
          "name": "Diet",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "UNC Lineberger Comprehensive Cancer Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 40,
      "start_date": "2025-06-03",
      "completion_date": "2026-12-31",
      "has_results": false,
      "last_update_posted_date": "2025-06-27",
      "last_synced_at": "2026-06-07T16:02:47.996Z",
      "location_count": 1,
      "location_summary": "Chapel Hill, North Carolina",
      "locations": [
        {
          "city": "Chapel Hill",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06860880"
    },
    {
      "nct_id": "NCT00100412",
      "title": "Hyporeactivity and Gulf War Illness",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Gulf War Syndrome",
        "Chronic Fatigue Syndrome",
        "Post-Traumatic Stress Disorder"
      ],
      "interventions": [
        {
          "name": "Graded dobutamine infusions",
          "type": "DRUG"
        },
        {
          "name": "Graded phenylephrine injections",
          "type": "DRUG"
        },
        {
          "name": "Psychosocial challenge involving socioevaluative public speaking",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "DRUG",
        "BEHAVIORAL"
      ],
      "sponsor": "US Department of Veterans Affairs",
      "sponsor_class": "FED",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": null,
      "start_date": "1999-10",
      "completion_date": "2002-09",
      "has_results": false,
      "last_update_posted_date": "2009-01-21",
      "last_synced_at": "2026-06-07T16:02:47.996Z",
      "location_count": 1,
      "location_summary": "East Orange, New Jersey",
      "locations": [
        {
          "city": "East Orange",
          "state": "New Jersey"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00100412"
    },
    {
      "nct_id": "NCT01919918",
      "title": "Muscle Afferent Feedback Effects in Patients With Heart Failure",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Chronic Heart Failure"
      ],
      "interventions": [
        {
          "name": "Muscle Contraction with Metabolite Solution Administration",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of Utah",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "20 Years",
        "maximum_age": "79 Years",
        "sex": "ALL",
        "summary": "20 Years to 79 Years"
      },
      "enrollment_count": 144,
      "start_date": "2013-09",
      "completion_date": "2018-01-03",
      "has_results": false,
      "last_update_posted_date": "2018-01-08",
      "last_synced_at": "2026-06-07T16:02:47.996Z",
      "location_count": 2,
      "location_summary": "Salt Lake City, Utah",
      "locations": [
        {
          "city": "Salt Lake City",
          "state": "Utah"
        },
        {
          "city": "Salt Lake City",
          "state": "Utah"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01919918"
    },
    {
      "nct_id": "NCT05200858",
      "title": "Transcutaneous Electrical Nerve Stimulation (TENS) in Patients With Postacute Sequelae of Sars-CoV-2",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Postacute Sequelae of Sars-CoV-2",
        "Post-Acute COVID-19 Syndrome",
        "Widespread Chronic Pain",
        "Fatigue Syndrome, Chronic",
        "Gait, Unsteady"
      ],
      "interventions": [
        {
          "name": "TENS - high-dose",
          "type": "DEVICE"
        },
        {
          "name": "TENS - low-dose",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Baylor College of Medicine",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 30,
      "start_date": "2022-03-01",
      "completion_date": "2023-12-01",
      "has_results": true,
      "last_update_posted_date": "2024-07-16",
      "last_synced_at": "2026-06-07T16:02:47.996Z",
      "location_count": 1,
      "location_summary": "Houston, Texas",
      "locations": [
        {
          "city": "Houston",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05200858"
    },
    {
      "nct_id": "NCT07523113",
      "title": "ME/CFS Brain Fog: Cognitive Rehabilitation Trial",
      "overall_status": "NOT_YET_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "ME/CFS",
        "ME/CFS Following EBV-associated Infectious Mononucleosis",
        "ME/CFS Following COVID-19",
        "Chronic Fatigue",
        "Chronic Fatigue Syndrome (CFS)",
        "Brain Fog",
        "Cognitive Impairment",
        "Cognitive Dysfunction"
      ],
      "interventions": [
        {
          "name": "Processing Speed Training",
          "type": "BEHAVIORAL"
        },
        {
          "name": "In-session Instrumental Activities of Daily Living Training",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Transfer Package",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Follow Up Phone Calls",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Trans-auricular Vagus Nerve Stimulation: High Intensity",
          "type": "PROCEDURE"
        },
        {
          "name": "In-session Brain Health Training",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Reaction Time Training",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Trans-auricular Vagus Nerve Stimulation: Low Intensity",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL",
        "PROCEDURE"
      ],
      "sponsor": "University of Alabama at Birmingham",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 30,
      "start_date": "2026-04",
      "completion_date": "2028-04",
      "has_results": false,
      "last_update_posted_date": "2026-04-13",
      "last_synced_at": "2026-06-07T16:02:47.996Z",
      "location_count": 1,
      "location_summary": "Birmingham, Alabama",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07523113"
    },
    {
      "nct_id": "NCT00540254",
      "title": "Behavioral Insomnia Therapy With Chronic Fatigue Syndrome",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1",
        "PHASE2"
      ],
      "conditions": [
        "Chronic Fatigue Syndrome",
        "Behavioral Therapy Targeted to Sleep Problems"
      ],
      "interventions": [
        {
          "name": "Cognitive Behavioral Therapy",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Usual Care for Chronic Fatigue Syndrome (Active Control Group)",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL",
        "OTHER"
      ],
      "sponsor": "Duke University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "21 Years to 65 Years"
      },
      "enrollment_count": 24,
      "start_date": "2007-09",
      "completion_date": "2010-07",
      "has_results": false,
      "last_update_posted_date": "2013-03-01",
      "last_synced_at": "2026-06-07T16:02:47.996Z",
      "location_count": 1,
      "location_summary": "Durham, North Carolina",
      "locations": [
        {
          "city": "Durham",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00540254"
    },
    {
      "nct_id": "NCT06511050",
      "title": "Lumbrokinase for Adults With Long Covid, Post-treatment Lyme Disease Syndrome, and Myalgic Encephalomyelitis/Chronic Fatigue Syndrome",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1",
        "PHASE2"
      ],
      "conditions": [
        "Long Covid",
        "Post-treatment Lyme Disease Syndrome",
        "Chronic Fatigue Syndrome",
        "Myalgic Encephalomyelitis"
      ],
      "interventions": [
        {
          "name": "Lumbrokinase",
          "type": "DIETARY_SUPPLEMENT"
        }
      ],
      "intervention_types": [
        "DIETARY_SUPPLEMENT"
      ],
      "sponsor": "Icahn School of Medicine at Mount Sinai",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 120,
      "start_date": "2024-10-09",
      "completion_date": "2026-12",
      "has_results": false,
      "last_update_posted_date": "2026-03-13",
      "last_synced_at": "2026-06-07T16:02:47.996Z",
      "location_count": 1,
      "location_summary": "New York, New York",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06511050"
    },
    {
      "nct_id": "NCT07317271",
      "title": "VR-PMR for Post-Burn Symptoms",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Burn",
        "Chronic Pain Following Thermal Burn Injury",
        "Non-Pharmacological Interventions",
        "Virtual Reality",
        "Sleep Disturbance",
        "Anxiety",
        "Depressive Symptoms",
        "Fatigue Symptom",
        "Pruritus",
        "Burn Injury",
        "Progressive Muscle Relaxation"
      ],
      "interventions": [
        {
          "name": "Virtual Reality-Enhanced Progressive Muscle Relaxation",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Standard Progressive Muscle Relaxation",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Johns Hopkins University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 34,
      "start_date": "2026-02-27",
      "completion_date": "2026-12",
      "has_results": false,
      "last_update_posted_date": "2026-03-05",
      "last_synced_at": "2026-06-07T16:02:47.996Z",
      "location_count": 1,
      "location_summary": "Baltimore, Maryland",
      "locations": [
        {
          "city": "Baltimore",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07317271"
    }
  ]
}