{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Chronic+Fatigue+Syndrome&page=4",
    "query": {
      "condition": "Chronic Fatigue Syndrome",
      "page": 4
    },
    "page_size": 10
  },
  "pagination": {
    "page": 4,
    "page_size": 10,
    "total_count": 131,
    "total_pages": 14,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Chronic+Fatigue+Syndrome&page=5&page_size=10",
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Chronic+Fatigue+Syndrome&page=3&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-10-07T05:26:05.587Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT05226078",
      "title": "The Association Between CBT-I Dose, Sleep Duration, and Fatigue in Breast Cancer Patients",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Chronic Insomnia",
        "Cancer-related Problem/Condition",
        "Cancer-Related Syndrome"
      ],
      "interventions": [
        {
          "name": "Cognitive Behavioral Therapy for Insomnia",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Abramson Cancer Center at Penn Medicine",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "25 Years",
        "maximum_age": "85 Years",
        "sex": "FEMALE",
        "summary": "25 Years to 85 Years · Female only"
      },
      "enrollment_count": 64,
      "start_date": "2023-03-01",
      "completion_date": "2026-11-30",
      "has_results": false,
      "last_update_posted_date": "2026-08-21",
      "last_synced_at": "2026-10-07T05:26:05.587Z",
      "location_count": 1,
      "location_summary": "Philadelphia, Pennsylvania",
      "locations": [
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05226078"
    },
    {
      "nct_id": "NCT05584124",
      "title": "Repetitive Transcranial Magnetic Stimulation, a Form of Non-invasive Brain Stimulation, as a Possible Treatment for Post-stroke Fatigue",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Stroke",
        "Stroke, Chronic",
        "Fatigue"
      ],
      "interventions": [
        {
          "name": "High frequency repetitive transcranial magnetic stimulation",
          "type": "DEVICE"
        },
        {
          "name": "Sham repetitive transcranial magnetic stimulation",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "VA Office of Research and Development",
      "sponsor_class": "FED",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "34 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "34 Years to 80 Years"
      },
      "enrollment_count": 60,
      "start_date": "2023-04-10",
      "completion_date": "2027-10-29",
      "has_results": false,
      "last_update_posted_date": "2026-09-14",
      "last_synced_at": "2026-10-07T05:26:05.587Z",
      "location_count": 2,
      "location_summary": "Decatur, Georgia • Charleston, South Carolina",
      "locations": [
        {
          "city": "Decatur",
          "state": "Georgia"
        },
        {
          "city": "Charleston",
          "state": "South Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05584124"
    },
    {
      "nct_id": "NCT04705831",
      "title": "Study to Evaluate the Benefit of RUCONEST in Improving Neurological Symptoms in Post COVID-19 Infection",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Post-Viral Fatigue Syndrome",
        "Post-Viral Disorder (Disorder)",
        "Covid19"
      ],
      "interventions": [
        {
          "name": "Ruconest",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "IMMUNOe Research Centers",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "18 Years to 75 Years"
      },
      "enrollment_count": 40,
      "start_date": "2021-01-11",
      "completion_date": "2024-07-01",
      "has_results": false,
      "last_update_posted_date": "2025-08-11",
      "last_synced_at": "2026-10-07T05:26:05.587Z",
      "location_count": 1,
      "location_summary": "Centennial, Colorado",
      "locations": [
        {
          "city": "Centennial",
          "state": "Colorado"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04705831"
    },
    {
      "nct_id": "NCT02965768",
      "title": "Immune Effects of Low-dose Naltrexone in ME/CFS",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Fatigue Syndrome, Chronic"
      ],
      "interventions": [
        {
          "name": "Naltrexone HCl",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of Alabama at Birmingham",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "FEMALE",
        "summary": "18 Years to 65 Years · Female only"
      },
      "enrollment_count": 0,
      "start_date": "2016-01",
      "completion_date": "2022-08-25",
      "has_results": false,
      "last_update_posted_date": "2022-09-02",
      "last_synced_at": "2026-10-07T05:26:05.587Z",
      "location_count": 1,
      "location_summary": "Birmingham, Alabama",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02965768"
    },
    {
      "nct_id": "NCT00810225",
      "title": "Study of Gulf War Illness (GWI) by Comparing GWI and Healthy Veterans",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Gulf War Illness",
        "Persian Gulf War Syndrome"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Georgetown University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 516,
      "start_date": "2008-08",
      "completion_date": "2011-07",
      "has_results": false,
      "last_update_posted_date": "2018-06-18",
      "last_synced_at": "2026-10-07T05:26:05.587Z",
      "location_count": 1,
      "location_summary": "Washington D.C., District of Columbia",
      "locations": [
        {
          "city": "Washington D.C.",
          "state": "District of Columbia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00810225"
    },
    {
      "nct_id": "NCT02530515",
      "title": "Ex Vivo-activated Autologous Lymph Node Lymphocytes in Treating Patients With Chronic Lymphocytic Leukemia",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Anemia",
        "Cancer Fatigue",
        "Chronic Lymphocytic Leukemia",
        "Fever",
        "Infectious Disorder",
        "Lymphadenopathy",
        "Lymphocytosis",
        "Night Sweats",
        "Prolymphocytic Leukemia",
        "Recurrent Chronic Lymphocytic Leukemia",
        "Richter Syndrome",
        "Secondary Malignant Neoplasm",
        "Thrombocytopenia",
        "Weight Loss"
      ],
      "interventions": [
        {
          "name": "Ex Vivo-activated Autologous Lymph Node Lymphocytes",
          "type": "BIOLOGICAL"
        },
        {
          "name": "Laboratory Biomarker Analysis",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "BIOLOGICAL",
        "OTHER"
      ],
      "sponsor": "M.D. Anderson Cancer Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 8,
      "start_date": "2015-12-18",
      "completion_date": "2018-04-30",
      "has_results": true,
      "last_update_posted_date": "2019-10-29",
      "last_synced_at": "2026-10-07T05:26:05.587Z",
      "location_count": 1,
      "location_summary": "Houston, Texas",
      "locations": [
        {
          "city": "Houston",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02530515"
    },
    {
      "nct_id": "NCT01873482",
      "title": "Traditional African Healing Ceremony in a U.S. Population",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Chronic Fatigue Syndrome",
        "Anxiety",
        "Depression",
        "Cancer"
      ],
      "interventions": [
        {
          "name": "Movement to rhythm",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Duke University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "25 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "25 Years to 65 Years"
      },
      "enrollment_count": 17,
      "start_date": "2014-05",
      "completion_date": null,
      "has_results": false,
      "last_update_posted_date": "2014-11-03",
      "last_synced_at": "2026-10-07T05:26:05.587Z",
      "location_count": 1,
      "location_summary": "Durham, North Carolina",
      "locations": [
        {
          "city": "Durham",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01873482"
    },
    {
      "nct_id": "NCT07285473",
      "title": "Low-Dose Naltrexone For ME/CFS: Dose-Finding",
      "overall_status": "NOT_YET_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Myalgic Encephalomyelitis/Chronic Fatigue Syndrome"
      ],
      "interventions": [
        {
          "name": "Low-Dose Naltrexone, 1.5mg",
          "type": "DRUG"
        },
        {
          "name": "Low-Dose Naltrexone, 3.0mg",
          "type": "DRUG"
        },
        {
          "name": "Low-Dose Naltrexone, 4.5mg",
          "type": "DRUG"
        },
        {
          "name": "Low-Dose Naltrexone, 6.0mg",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of Alabama at Birmingham",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 75,
      "start_date": "2026-10-01",
      "completion_date": "2028-04-01",
      "has_results": false,
      "last_update_posted_date": "2026-08-21",
      "last_synced_at": "2026-10-07T05:26:05.587Z",
      "location_count": 1,
      "location_summary": "Birmingham, Alabama",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07285473"
    },
    {
      "nct_id": "NCT02948556",
      "title": "ME/CFS: Activity Patterns and Autonomic Dysfunction",
      "overall_status": "UNKNOWN",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Chronic Fatigue Syndrome"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Stony Brook University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 150,
      "start_date": "2016-06",
      "completion_date": "2020-05",
      "has_results": false,
      "last_update_posted_date": "2016-11-03",
      "last_synced_at": "2026-10-07T05:26:05.587Z",
      "location_count": 1,
      "location_summary": "Stony Brook, New York",
      "locations": [
        {
          "city": "Stony Brook",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02948556"
    },
    {
      "nct_id": "NCT00252629",
      "title": "Sleep Disordered Breathing in Gulf War Illness and the Effect of Nasal CPAP Treatment",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Apnea, Sleep",
        "Chronic Fatigue Syndrome"
      ],
      "interventions": [
        {
          "name": "Nasal CPAP treatment during sleep",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "US Department of Veterans Affairs",
      "sponsor_class": "FED",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "32 Years",
        "maximum_age": "52 Years",
        "sex": "MALE",
        "summary": "32 Years to 52 Years · Male only"
      },
      "enrollment_count": 29,
      "start_date": "2005-11",
      "completion_date": "2010-11",
      "has_results": true,
      "last_update_posted_date": "2014-12-11",
      "last_synced_at": "2026-10-07T05:26:05.587Z",
      "location_count": 1,
      "location_summary": "Northport, New York",
      "locations": [
        {
          "city": "Northport",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00252629"
    }
  ]
}