{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Chronic+HBV+Infection&page=2", "query": { "condition": "Chronic HBV Infection", "page": 2 }, "page_size": 10 }, "pagination": { "page": 2, "page_size": 10, "total_count": 171, "total_pages": 18, "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Chronic+HBV+Infection&page=3&page_size=10", "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Chronic+HBV+Infection&page=1&page_size=10" }, "source": "remote", "last_synced_at": "2026-09-30T08:02:55.519Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT04629976", "title": "Activity of NCO-48 Fumarate in Treatment-Naive Adults With Chronic Hepatitis B", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "Chronic Hepatitis B" ], "interventions": [ { "name": "NCO-48 Fumarate 4 mg", "type": "DRUG" }, { "name": "NCO-48 Fumarate 20 mg", "type": "DRUG" }, { "name": "Tenofovir Alafenamide 25 mg", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Nucorion Pharmaceuticals, Inc.", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "65 Years", "sex": "ALL", "summary": "18 Years to 65 Years" }, "enrollment_count": 21, "start_date": "2021-01-12", "completion_date": "2022-12-28", "has_results": false, "last_update_posted_date": "2023-01-04", "last_synced_at": "2026-09-30T08:02:55.519Z", "location_count": 1, "location_summary": "Monterey Park, California", "locations": [ { "city": "Monterey Park", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT04629976" }, { "nct_id": "NCT03982186", "title": "A Study of Different Combination Regimens Including JNJ-73763989 and/or JNJ-56136379 for the Treatment of Chronic Hepatitis B Virus Infection", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Hepatitis B, Chronic" ], "interventions": [ { "name": "JNJ-73763989", "type": "DRUG" }, { "name": "Placebo for JNJ-73763989", "type": "DRUG" }, { "name": "JNJ-56136379", "type": "DRUG" }, { "name": "Placebo for JNJ-56136379", "type": "DRUG" }, { "name": "Nucleos(t)ide Analog (NA)", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Janssen Sciences Ireland UC", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "65 Years", "sex": "ALL", "summary": "18 Years to 65 Years" }, "enrollment_count": 471, "start_date": "2019-08-01", "completion_date": "2022-04-26", "has_results": true, "last_update_posted_date": "2025-02-04", "last_synced_at": "2026-09-30T08:02:55.519Z", "location_count": 8, "location_summary": "Bakersfield, California • Los Angeles, California • San Clemente, California + 5 more", "locations": [ { "city": "Bakersfield", "state": "California" }, { "city": "Los Angeles", "state": "California" }, { "city": "San Clemente", "state": "California" }, { "city": "Washington D.C.", "state": "District of Columbia" }, { "city": "Baltimore", "state": "Maryland" } ], "official_url": "https://clinicaltrials.gov/study/NCT03982186" }, { "nct_id": "NCT06154278", "title": "Intrahepatic and Peripheral Responses to Imdusiran (AB-729) in Chronic Hepatitis B", "overall_status": "RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Chronic Hepatitis B" ], "interventions": [ { "name": "Imdusiran (AB-729)", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "University of Maryland, Baltimore", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 10, "start_date": "2024-07-25", "completion_date": "2027-07-01", "has_results": false, "last_update_posted_date": "2025-09-11", "last_synced_at": "2026-09-30T08:02:55.519Z", "location_count": 1, "location_summary": "Baltimore, Maryland", "locations": [ { "city": "Baltimore", "state": "Maryland" } ], "official_url": "https://clinicaltrials.gov/study/NCT06154278" }, { "nct_id": "NCT01859884", "title": "Optimizing Kidney Transplant Informed Consent", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "End-stage Kidney Disease" ], "interventions": [ { "name": "Inform Me: web-based education tool", "type": "BEHAVIORAL" } ], "intervention_types": [ "BEHAVIORAL" ], "sponsor": "Northwestern University", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "21 Years", "maximum_age": null, "sex": "ALL", "summary": "21 Years and older" }, "enrollment_count": 288, "start_date": "2013-10", "completion_date": "2015-11", "has_results": false, "last_update_posted_date": "2015-11-20", "last_synced_at": "2026-09-30T08:02:55.519Z", "location_count": 2, "location_summary": "Birmingham, Alabama • Chicago, Illinois", "locations": [ { "city": "Birmingham", "state": "Alabama" }, { "city": "Chicago", "state": "Illinois" } ], "official_url": "https://clinicaltrials.gov/study/NCT01859884" }, { "nct_id": "NCT07342881", "title": "Single Dose Study to Evaluate the Pharmacokinetics, Safety and Tolerability of Pevifoscorvir Sodium (ALG-000184) in Participants With Renal Impairment and in Healthy Participants With Normal Renal Function", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "Chronic Hepatitis B Infection" ], "interventions": [ { "name": "Pevifoscorvir Sodium (ALG-000184)", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Aligos Therapeutics", "sponsor_class": "INDUSTRY", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "75 Years", "sex": "ALL", "summary": "18 Years to 75 Years" }, "enrollment_count": 12, "start_date": "2026-03-10", "completion_date": "2026-07-29", "has_results": false, "last_update_posted_date": "2026-08-21", "last_synced_at": "2026-09-30T08:02:55.519Z", "location_count": 2, "location_summary": "Orlando, Florida • Tampa, Florida", "locations": [ { "city": "Orlando", "state": "Florida" }, { "city": "Tampa", "state": "Florida" } ], "official_url": "https://clinicaltrials.gov/study/NCT07342881" }, { "nct_id": "NCT00496002", "title": "Efficacy and Safety of Clevudine Compared With Adefovir in Patients With HBeAg Positive Chronic Hepatitis Due to Hepatitis B Virus", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Chronic Hepatitis", "Hepatitis B" ], "interventions": [ { "name": "Clevudine", "type": "DRUG" }, { "name": "Adefovir", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Pharmasset", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "16 Years", "maximum_age": null, "sex": "ALL", "summary": "16 Years and older" }, "enrollment_count": null, "start_date": "2007-08", "completion_date": null, "has_results": false, "last_update_posted_date": "2009-04-27", "last_synced_at": "2026-09-30T08:02:55.519Z", "location_count": 66, "location_summary": "Birmingham, Alabama • Anaheim, California • Fresno, California + 35 more", "locations": [ { "city": "Birmingham", "state": "Alabama" }, { "city": "Anaheim", "state": "California" }, { "city": "Anaheim", "state": "California" }, { "city": "Fresno", "state": "California" }, { "city": "Fresno", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT00496002" }, { "nct_id": "NCT02258581", "title": "Long Term Follow-up Registry of Individuals Treated in A Gilead-Sponsored Trial in Individuals With Chronic Hepatitis B Infection", "overall_status": "TERMINATED", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Chronic Hepatitis B" ], "interventions": [ { "name": "GS-4774", "type": "DRUG" }, { "name": "GS-9620", "type": "DRUG" }, { "name": "Tenofovir disoproxil fumarate (TDF)", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Gilead Sciences", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 241, "start_date": "2014-12-09", "completion_date": "2017-08-14", "has_results": false, "last_update_posted_date": "2017-10-03", "last_synced_at": "2026-09-30T08:02:55.519Z", "location_count": 16, "location_summary": "Sacramento, California • San Diego, California • San Francisco, California + 13 more", "locations": [ { "city": "Sacramento", "state": "California" }, { "city": "San Diego", "state": "California" }, { "city": "San Francisco", "state": "California" }, { "city": "San Jose", "state": "California" }, { "city": "Miami", "state": "Florida" } ], "official_url": "https://clinicaltrials.gov/study/NCT02258581" }, { "nct_id": "NCT00376259", "title": "Study of Combination Therapy With LdT Plus Adefovir Versus Adefovir Alone", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Hepatitis B" ], "interventions": [ { "name": "telbivudine", "type": "DRUG" }, { "name": "adefovir dipivoxil", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Novartis", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "70 Years", "sex": "ALL", "summary": "18 Years to 70 Years" }, "enrollment_count": 43, "start_date": "2007-01", "completion_date": null, "has_results": true, "last_update_posted_date": "2011-06-30", "last_synced_at": "2026-09-30T08:02:55.519Z", "location_count": 2, "location_summary": "San Diego, California • San Mateo, California", "locations": [ { "city": "San Diego", "state": "California" }, { "city": "San Mateo", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT00376259" }, { "nct_id": "NCT00040144", "title": "Safety and Antiviral Study of ACH126, 433 (b-L-Fd4C) in Adults With Lamivudine-resistant Chronic Hepatitis B", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Chronic Hepatitis B" ], "interventions": [ { "name": "ACH126, 433", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Alexion Pharmaceuticals, Inc.", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 85, "start_date": "2002-07", "completion_date": "2003-05", "has_results": false, "last_update_posted_date": "2021-02-18", "last_synced_at": "2026-09-30T08:02:55.519Z", "location_count": 13, "location_summary": "Los Angeles, California • Orange, California • Pasadena, California + 8 more", "locations": [ { "city": "Los Angeles", "state": "California" }, { "city": "Orange", "state": "California" }, { "city": "Pasadena", "state": "California" }, { "city": "San Francisco", "state": "California" }, { "city": "Miami", "state": "Florida" } ], "official_url": "https://clinicaltrials.gov/study/NCT00040144" }, { "nct_id": "NCT00116805", "title": "A Study to Compare Tenofovir Disoproxil Fumarate Versus Adefovir Dipivoxil for the Treatment of HBeAg-Positive Chronic Hepatitis B", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Chronic Hepatitis B" ], "interventions": [ { "name": "TDF", "type": "DRUG" }, { "name": "ADV", "type": "DRUG" }, { "name": "TDF placebo", "type": "DRUG" }, { "name": "ADV placebo", "type": "DRUG" }, { "name": "FTC/TDF", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Gilead Sciences", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "69 Years", "sex": "ALL", "summary": "18 Years to 69 Years" }, "enrollment_count": 266, "start_date": "2005-06", "completion_date": "2016-01", "has_results": true, "last_update_posted_date": "2017-03-09", "last_synced_at": "2026-09-30T08:02:55.519Z", "location_count": 20, "location_summary": "Orange, California • Pasadena, California • San Diego, California + 14 more", "locations": [ { "city": "Orange", "state": "California" }, { "city": "Pasadena", "state": "California" }, { "city": "San Diego", "state": "California" }, { "city": "San Jose", "state": "California" }, { "city": "Miami", "state": "Florida" } ], "official_url": "https://clinicaltrials.gov/study/NCT00116805" } ] }