{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Chronic+Headaches",
    "query": {
      "condition": "Chronic Headaches"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 187,
    "total_pages": 19,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Chronic+Headaches&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-05-22T05:38:57.301Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT04825678",
      "title": "A Study to Evaluate Treatment Satisfaction With Erenumab in Participants With Migraine",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Migraine"
      ],
      "interventions": [
        {
          "name": "Erenumab",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Amgen",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "99 Years",
        "sex": "ALL",
        "summary": "18 Years to 99 Years"
      },
      "enrollment_count": 240,
      "start_date": "2021-06-11",
      "completion_date": "2023-09-28",
      "has_results": true,
      "last_update_posted_date": "2024-09-19",
      "last_synced_at": "2026-05-22T05:38:57.301Z",
      "location_count": 42,
      "location_summary": "Huntsville, Alabama • Phoenix, Arizona • Fullerton, California + 38 more",
      "locations": [
        {
          "city": "Huntsville",
          "state": "Alabama"
        },
        {
          "city": "Phoenix",
          "state": "Arizona"
        },
        {
          "city": "Fullerton",
          "state": "California"
        },
        {
          "city": "Pomona",
          "state": "California"
        },
        {
          "city": "Basalt",
          "state": "Colorado"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04825678"
    },
    {
      "nct_id": "NCT00810225",
      "title": "Study of Gulf War Illness (GWI) by Comparing GWI and Healthy Veterans",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Gulf War Illness",
        "Persian Gulf War Syndrome"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Georgetown University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 516,
      "start_date": "2008-08",
      "completion_date": "2011-07",
      "has_results": false,
      "last_update_posted_date": "2018-06-18",
      "last_synced_at": "2026-05-22T05:38:57.301Z",
      "location_count": 1,
      "location_summary": "Washington D.C., District of Columbia",
      "locations": [
        {
          "city": "Washington D.C.",
          "state": "District of Columbia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00810225"
    },
    {
      "nct_id": "NCT05216263",
      "title": "Study of Oral Atogepant When Added to OnabotulinumtoxinA (BOTOX) to Assess Adverse Events and Change in Disease Activity in Adult Participants With Chronic Migraine",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Chronic Migraine"
      ],
      "interventions": [
        {
          "name": "Atogepant",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "AbbVie",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "18 Years to 75 Years"
      },
      "enrollment_count": 75,
      "start_date": "2022-03-22",
      "completion_date": "2025-05-02",
      "has_results": false,
      "last_update_posted_date": "2025-05-16",
      "last_synced_at": "2026-05-22T05:38:57.301Z",
      "location_count": 29,
      "location_summary": "Hoover, Alabama • Phoenix, Arizona • Little Rock, Arkansas + 25 more",
      "locations": [
        {
          "city": "Hoover",
          "state": "Alabama"
        },
        {
          "city": "Phoenix",
          "state": "Arizona"
        },
        {
          "city": "Little Rock",
          "state": "Arkansas"
        },
        {
          "city": "Canoga Park",
          "state": "California"
        },
        {
          "city": "Carlsbad",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05216263"
    },
    {
      "nct_id": "NCT00219869",
      "title": "Galantamine in the Treatment of Post-Traumatic Headache",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Post-Traumatic Headache",
        "Head Trauma,Closed",
        "Retention Disorders,Cognitive"
      ],
      "interventions": [
        {
          "name": "Galantamine",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Rapoport, Alan, M.D.",
      "sponsor_class": "INDIV",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "18 Years to 75 Years"
      },
      "enrollment_count": 30,
      "start_date": "2005-07",
      "completion_date": "2005-08",
      "has_results": false,
      "last_update_posted_date": "2005-09-22",
      "last_synced_at": "2026-05-22T05:38:57.301Z",
      "location_count": 1,
      "location_summary": "Stamford, Connecticut",
      "locations": [
        {
          "city": "Stamford",
          "state": "Connecticut"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00219869"
    },
    {
      "nct_id": "NCT02985398",
      "title": "An Open Label Trial of ALD403 (Eptinezumab) in Chronic Migraine",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Migraine Disorder"
      ],
      "interventions": [
        {
          "name": "ALD403 (Eptinezumab)",
          "type": "BIOLOGICAL"
        }
      ],
      "intervention_types": [
        "BIOLOGICAL"
      ],
      "sponsor": "Alder Biopharmaceuticals, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 128,
      "start_date": "2016-12",
      "completion_date": "2019-03",
      "has_results": true,
      "last_update_posted_date": "2020-04-21",
      "last_synced_at": "2026-05-22T05:38:57.301Z",
      "location_count": 20,
      "location_summary": "San Diego, California • Santa Monica, California • Colorado Springs, Colorado + 17 more",
      "locations": [
        {
          "city": "San Diego",
          "state": "California"
        },
        {
          "city": "Santa Monica",
          "state": "California"
        },
        {
          "city": "Colorado Springs",
          "state": "Colorado"
        },
        {
          "city": "Bradenton",
          "state": "Florida"
        },
        {
          "city": "DeLand",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02985398"
    },
    {
      "nct_id": "NCT01986205",
      "title": "Hyperbaric Oxygen for Traumatic and Non-traumatic Brain Injury",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Brain Injury, Chronic"
      ],
      "interventions": [
        {
          "name": "Hyperbaric Oxygen",
          "type": "COMBINATION_PRODUCT"
        },
        {
          "name": "Minimal pressure air",
          "type": "COMBINATION_PRODUCT"
        }
      ],
      "intervention_types": [
        "COMBINATION_PRODUCT"
      ],
      "sponsor": "Lindell Weaver",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "70 Years",
        "sex": "ALL",
        "summary": "18 Years to 70 Years"
      },
      "enrollment_count": 49,
      "start_date": "2017-09-06",
      "completion_date": "2022-05-31",
      "has_results": false,
      "last_update_posted_date": "2022-08-04",
      "last_synced_at": "2026-05-22T05:38:57.301Z",
      "location_count": 2,
      "location_summary": "Murray, Utah • Salt Lake City, Utah",
      "locations": [
        {
          "city": "Murray",
          "state": "Utah"
        },
        {
          "city": "Salt Lake City",
          "state": "Utah"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01986205"
    },
    {
      "nct_id": "NCT02959294",
      "title": "Use of Adipose-Derived Stem/Stromal Cells in Concussion and Traumatic Brain Injuries",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "EARLY_PHASE1"
      ],
      "conditions": [
        "Traumatic Encephalopathies, Chronic",
        "Concussion, Mild",
        "Concussion, Intermediate",
        "Concussion, Severe",
        "Concussion, Brain"
      ],
      "interventions": [
        {
          "name": "Microcannula Harvest Adipose",
          "type": "PROCEDURE"
        },
        {
          "name": "Centricyte 1000",
          "type": "DEVICE"
        },
        {
          "name": "Sterile Normal Saline IV deployment AD-cSVF",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE",
        "DEVICE"
      ],
      "sponsor": "Robert W. Alexander, MD, FICS",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "16 Years",
        "maximum_age": "70 Years",
        "sex": "ALL",
        "summary": "16 Years to 70 Years"
      },
      "enrollment_count": 0,
      "start_date": "2018-11-30",
      "completion_date": "2024-03",
      "has_results": false,
      "last_update_posted_date": "2021-02-16",
      "last_synced_at": "2026-05-22T05:38:57.301Z",
      "location_count": 1,
      "location_summary": "Stevensville, Montana",
      "locations": [
        {
          "city": "Stevensville",
          "state": "Montana"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02959294"
    },
    {
      "nct_id": "NCT04672044",
      "title": "TMS and Exercise for Post-stroke Pain",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Chronic Post-stroke Headache"
      ],
      "interventions": [
        {
          "name": "Active rTMS and exercise",
          "type": "DEVICE"
        },
        {
          "name": "Sham rTMS+Exercise",
          "type": "COMBINATION_PRODUCT"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "COMBINATION_PRODUCT"
      ],
      "sponsor": "VA Office of Research and Development",
      "sponsor_class": "FED",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "19 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "19 Years and older"
      },
      "enrollment_count": 9,
      "start_date": "2022-01-14",
      "completion_date": "2024-12-30",
      "has_results": true,
      "last_update_posted_date": "2025-06-15",
      "last_synced_at": "2026-05-22T05:38:57.301Z",
      "location_count": 1,
      "location_summary": "Birmingham, Alabama",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04672044"
    },
    {
      "nct_id": "NCT02383472",
      "title": "LED Therapy for the Treatment of Concussive Brain Injury",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Brain Concussion"
      ],
      "interventions": [
        {
          "name": "MedX Health Console model 1100",
          "type": "DEVICE"
        },
        {
          "name": "MedX Health Console model 1100-placebo",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Boston Children's Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "11 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "11 Years and older"
      },
      "enrollment_count": 53,
      "start_date": "2012-09",
      "completion_date": "2016-05",
      "has_results": true,
      "last_update_posted_date": "2018-07-26",
      "last_synced_at": "2026-05-22T05:38:57.301Z",
      "location_count": 2,
      "location_summary": "Boston, Massachusetts • Waltham, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        },
        {
          "city": "Waltham",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02383472"
    },
    {
      "nct_id": "NCT03832998",
      "title": "Efficacy and Safety of Erenumab in Pediatric Subjects With Chronic Migraine",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Migraine"
      ],
      "interventions": [
        {
          "name": "Erenumab Dose 1",
          "type": "DRUG"
        },
        {
          "name": "Erenumab Dose 2",
          "type": "DRUG"
        },
        {
          "name": "Erenumab Dose 3",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DRUG",
        "OTHER"
      ],
      "sponsor": "Amgen",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "6 Years",
        "maximum_age": "17 Years",
        "sex": "ALL",
        "summary": "6 Years to 17 Years"
      },
      "enrollment_count": 284,
      "start_date": "2019-09-05",
      "completion_date": "2026-01-07",
      "has_results": false,
      "last_update_posted_date": "2026-01-20",
      "last_synced_at": "2026-05-22T05:38:57.301Z",
      "location_count": 38,
      "location_summary": "San Diego, California • Aurora, Colorado • Colorado Springs, Colorado + 33 more",
      "locations": [
        {
          "city": "San Diego",
          "state": "California"
        },
        {
          "city": "Aurora",
          "state": "Colorado"
        },
        {
          "city": "Colorado Springs",
          "state": "Colorado"
        },
        {
          "city": "Stamford",
          "state": "Connecticut"
        },
        {
          "city": "Washington D.C.",
          "state": "District of Columbia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03832998"
    }
  ]
}