{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Chronic+Heart+Disease&page=5",
    "query": {
      "condition": "Chronic Heart Disease",
      "page": 5
    },
    "page_size": 10
  },
  "pagination": {
    "page": 5,
    "page_size": 10,
    "total_count": 601,
    "total_pages": 61,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Chronic+Heart+Disease&page=6&page_size=10",
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Chronic+Heart+Disease&page=4&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-10-05T12:38:27.091Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT00405548",
      "title": "Human Brain Natriuretic Peptide (BNP) (or Nesiritide) to Help Heart, Kidney and Humoral Function.",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1",
        "PHASE2"
      ],
      "conditions": [
        "Left Ventricular Diastolic Dysfunction"
      ],
      "interventions": [
        {
          "name": "BNP (nesiritide)",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Mayo Clinic",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 41,
      "start_date": "2008-03",
      "completion_date": "2012-08",
      "has_results": true,
      "last_update_posted_date": "2015-07-01",
      "last_synced_at": "2026-10-05T12:38:27.091Z",
      "location_count": 1,
      "location_summary": "Rochester, Minnesota",
      "locations": [
        {
          "city": "Rochester",
          "state": "Minnesota"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00405548"
    },
    {
      "nct_id": "NCT01337726",
      "title": "Combined Illness Management and Psychotherapy in Treating Depressed Elders",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Depression",
        "Heart Failure",
        "Chronic Obstructive Pulmonary Disease"
      ],
      "interventions": [
        {
          "name": "Combined Psychotherapy and Illness Management",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Illness Management Only",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of Iowa",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "55 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "55 Years and older"
      },
      "enrollment_count": 226,
      "start_date": "2011-02",
      "completion_date": "2016-10",
      "has_results": false,
      "last_update_posted_date": "2017-04-05",
      "last_synced_at": "2026-10-05T12:38:27.091Z",
      "location_count": 2,
      "location_summary": "Iowa City, Iowa",
      "locations": [
        {
          "city": "Iowa City",
          "state": "Iowa"
        },
        {
          "city": "Iowa City",
          "state": "Iowa"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01337726"
    },
    {
      "nct_id": "NCT07493096",
      "title": "Intensive Multimodal Neurorehabilitation Targeting Neuroplasticity in Pediatric Neurodevelopmental and Chromosomal Disorders",
      "overall_status": "RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Neurodevelopmental Disorders",
        "Neurodevelopmental Disorders (NDD)",
        "Neurodevelopmental Disorders and Developmental Abnormalities",
        "Developmental Delay (Disorder)",
        "Cerebral Palsy (CP)",
        "Cerebral Palsy Hemiparetic Cerebral Palsy Spasticity Gait Disorders, Neurologic Postural Balance Impairment",
        "Cerebral Palsy Infantile",
        "Cerebral Palsy Spastic Hemiplegic",
        "Cerebral Palsy, Dyskinetic",
        "Autism Spectrum Disorder",
        "Autism Spectrum Disorder (ASD",
        "Hypoxic Ischemic Encephalopathy",
        "Hypoxic Ischemic Encephalopathy (HIE)",
        "Traumatic Brain Injury (TBI)",
        "Sensory Processing Disorder",
        "Chromosomal Abnormalities",
        "Genetic Disorders",
        "Down Syndrome (Trisomy 21)",
        "Fragile X Syndrome (FXS)",
        "RETT Syndrome With Proven MECP2 Mutation",
        "Williams Syndrome",
        "22q11.2 Deletion Syndrome",
        "Sensorimotor Integration"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Healing Hope International",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "4 Years",
        "maximum_age": "12 Years",
        "sex": "ALL",
        "summary": "4 Years to 12 Years"
      },
      "enrollment_count": 100,
      "start_date": "2026-03-01",
      "completion_date": "2036-12-30",
      "has_results": false,
      "last_update_posted_date": "2026-03-25",
      "last_synced_at": "2026-10-05T12:38:27.091Z",
      "location_count": 1,
      "location_summary": "The Woodlands, Texas",
      "locations": [
        {
          "city": "The Woodlands",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07493096"
    },
    {
      "nct_id": "NCT03774394",
      "title": "Impact of Chronic Kidney Disease on Clopidogrel Effects in Diabetes Mellitus",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Chronic Kidney Disease (CKD)",
        "Type 2 Diabetes Mellitus (T2DM)",
        "Coronary Artery Disease (CAD)"
      ],
      "interventions": [
        {
          "name": "Clopidogrel",
          "type": "DRUG"
        },
        {
          "name": "Clopidogrel active metabolite",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of Florida",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 61,
      "start_date": "2019-08-22",
      "completion_date": "2022-05-31",
      "has_results": true,
      "last_update_posted_date": "2023-08-21",
      "last_synced_at": "2026-10-05T12:38:27.091Z",
      "location_count": 1,
      "location_summary": "Jacksonville, Florida",
      "locations": [
        {
          "city": "Jacksonville",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03774394"
    },
    {
      "nct_id": "NCT02984124",
      "title": "Communication During Hospitalization About Resuscitation Trial",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2",
        "PHASE3"
      ],
      "conditions": [
        "Severe Life-limiting COPD",
        "Severe Life-limiting Heart Failure",
        "Severe Life-limiting Cirrhosis",
        "Severe Life-limiting Malignancy",
        "Severe Functional Impairment",
        "End Stage Renal Disease"
      ],
      "interventions": [
        {
          "name": "Informed Assent Discussion",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Usual Care with Attention Control",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of Vermont",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "65 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "65 Years and older"
      },
      "enrollment_count": 182,
      "start_date": "2016-12",
      "completion_date": "2025-12",
      "has_results": false,
      "last_update_posted_date": "2026-05-29",
      "last_synced_at": "2026-10-05T12:38:27.091Z",
      "location_count": 4,
      "location_summary": "Chapel Hill, North Carolina • Charleston, South Carolina • Burlington, Vermont + 1 more",
      "locations": [
        {
          "city": "Chapel Hill",
          "state": "North Carolina"
        },
        {
          "city": "Charleston",
          "state": "South Carolina"
        },
        {
          "city": "Burlington",
          "state": "Vermont"
        },
        {
          "city": "Seattle",
          "state": "Washington"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02984124"
    },
    {
      "nct_id": "NCT01426542",
      "title": "Preventing Brain Injury in Infants With Congenital Heart Disease",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Cyanotic Congenital Heart Disease"
      ],
      "interventions": [
        {
          "name": "Topiramate",
          "type": "DRUG"
        },
        {
          "name": "No medication, but routine heart surgery",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DRUG",
        "OTHER"
      ],
      "sponsor": "University of California, Davis",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": "2 Months",
        "sex": "ALL",
        "summary": "Up to 2 Months"
      },
      "enrollment_count": 24,
      "start_date": "2011-03",
      "completion_date": "2017-07-28",
      "has_results": false,
      "last_update_posted_date": "2019-02-08",
      "last_synced_at": "2026-10-05T12:38:27.091Z",
      "location_count": 1,
      "location_summary": "Sacramento, California",
      "locations": [
        {
          "city": "Sacramento",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01426542"
    },
    {
      "nct_id": "NCT04998942",
      "title": "Virtual Cardiac Wellness Program Following Hypertensive Disorders of Pregnancy",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Hypertension in Pregnancy",
        "Gestational Hypertension",
        "Preeclampsia",
        "Chronic Hypertension With Pre-Eclampsia",
        "Eclampsia",
        "Chronic Hypertension in Obstetric Context"
      ],
      "interventions": [
        {
          "name": "virtual cardiac wellness program",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Placebo comparator",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Massachusetts General Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "FEMALE",
        "summary": "18 Years and older · Female only"
      },
      "enrollment_count": 100,
      "start_date": "2021-08-11",
      "completion_date": "2023-06",
      "has_results": false,
      "last_update_posted_date": "2023-05-10",
      "last_synced_at": "2026-10-05T12:38:27.091Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04998942"
    },
    {
      "nct_id": "NCT07403669",
      "title": "Cardiovascular Kidney and Metabolic Health Assessment and Patient Empowerment",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Acute MI",
        "Heart Failure",
        "Diabetes Mellitus",
        "Kidney Disease"
      ],
      "interventions": [
        {
          "name": "CHAPERONE AI",
          "type": "OTHER"
        },
        {
          "name": "CKMiq AI",
          "type": "DEVICE"
        },
        {
          "name": "Quality of Life",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER",
        "DEVICE"
      ],
      "sponsor": "Aventyn, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 300,
      "start_date": "2025-10-22",
      "completion_date": "2027-04-22",
      "has_results": false,
      "last_update_posted_date": "2026-02-12",
      "last_synced_at": "2026-10-05T12:38:27.091Z",
      "location_count": 4,
      "location_summary": "Chandler, Arizona • Gilbert, Arizona • Phoenix, Arizona + 1 more",
      "locations": [
        {
          "city": "Chandler",
          "state": "Arizona"
        },
        {
          "city": "Gilbert",
          "state": "Arizona"
        },
        {
          "city": "Phoenix",
          "state": "Arizona"
        },
        {
          "city": "San Tan Valley",
          "state": "Arizona"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07403669"
    },
    {
      "nct_id": "NCT05440084",
      "title": "Impact of CTO PCI (Chronic Total Occlusion Percutaneous Intervention) on Regular Physical Activity",
      "overall_status": "TERMINATED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Chronic Total Occlusion",
        "Occlusion"
      ],
      "interventions": [
        {
          "name": "Chronic total occlusion percutaneous coronary intervention",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Minneapolis Heart Institute Foundation",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 1,
      "start_date": "2022-09-01",
      "completion_date": "2024-09-01",
      "has_results": false,
      "last_update_posted_date": "2025-01-24",
      "last_synced_at": "2026-10-05T12:38:27.091Z",
      "location_count": 1,
      "location_summary": "Minneapolis, Minnesota",
      "locations": [
        {
          "city": "Minneapolis",
          "state": "Minnesota"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05440084"
    },
    {
      "nct_id": "NCT02302612",
      "title": "The CREATE Wellness Study",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Diabetes",
        "Heart Disease",
        "Hypertension",
        "Dyslipidemia"
      ],
      "interventions": [
        {
          "name": "CREATE Wellness",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Usual Care Control",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL",
        "OTHER"
      ],
      "sponsor": "Kaiser Permanente",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "40 Years",
        "maximum_age": "85 Years",
        "sex": "ALL",
        "summary": "40 Years to 85 Years"
      },
      "enrollment_count": 647,
      "start_date": "2015-01",
      "completion_date": "2018-09-30",
      "has_results": false,
      "last_update_posted_date": "2018-10-16",
      "last_synced_at": "2026-10-05T12:38:27.091Z",
      "location_count": 1,
      "location_summary": "San Jose, California",
      "locations": [
        {
          "city": "San Jose",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02302612"
    }
  ]
}