{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Chronic+Kidney+Disease+%28Stages+4+and+5%29",
    "query": {
      "condition": "Chronic Kidney Disease (Stages 4 and 5)"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 23,
    "total_pages": 3,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Chronic+Kidney+Disease+%28Stages+4+and+5%29&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-06-10T12:25:16.703Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT00621972",
      "title": "AV Fistula Salvage in Advanced CKD Using Sodium Bicarbonate Prophylaxis",
      "overall_status": "WITHDRAWN",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Acute Renal Failure"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "MaineHealth",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 0,
      "start_date": "2008-01",
      "completion_date": "2009-11",
      "has_results": false,
      "last_update_posted_date": "2018-09-20",
      "last_synced_at": "2026-06-10T12:25:16.703Z",
      "location_count": 1,
      "location_summary": "Portland, Maine",
      "locations": [
        {
          "city": "Portland",
          "state": "Maine"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00621972"
    },
    {
      "nct_id": "NCT07385651",
      "title": "Deceased Donor Kidney Storage at 10 Celsius Versus Conventional Storage",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "End Stage Chronic Renal Failure",
        "Chronic Kidney Disease (Stages 4 and 5)",
        "Kidney Transplantation Recipients"
      ],
      "interventions": [
        {
          "name": "10˚C deceased donor kidney storage using Traferox XPort",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Vanderbilt University Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 30,
      "start_date": "2024-11-18",
      "completion_date": "2027-12",
      "has_results": false,
      "last_update_posted_date": "2026-04-06",
      "last_synced_at": "2026-06-10T12:25:16.703Z",
      "location_count": 1,
      "location_summary": "Nashville, Tennessee",
      "locations": [
        {
          "city": "Nashville",
          "state": "Tennessee"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07385651"
    },
    {
      "nct_id": "NCT03036839",
      "title": "Ledipasvir/Sofosbuvir in Adults With Chronic Hepatitis C Virus (HCV) Infection Who Are on Dialysis for End Stage Renal Disease",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Hepatitis C Virus Infection"
      ],
      "interventions": [
        {
          "name": "LDV/SOF",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Gilead Sciences",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 95,
      "start_date": "2017-06-27",
      "completion_date": "2019-02-14",
      "has_results": true,
      "last_update_posted_date": "2020-03-02",
      "last_synced_at": "2026-06-10T12:25:16.703Z",
      "location_count": 6,
      "location_summary": "Boston, Massachusetts • Detroit, Michigan • The Bronx, New York + 3 more",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        },
        {
          "city": "Detroit",
          "state": "Michigan"
        },
        {
          "city": "The Bronx",
          "state": "New York"
        },
        {
          "city": "Dallas",
          "state": "Texas"
        },
        {
          "city": "San Antonio",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03036839"
    },
    {
      "nct_id": "NCT00257920",
      "title": "A Study of Zemplar® Injection and Hectorol® Injection on Intestinal Absorption of Calcium in Chronic Kidney Disease",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Chronic Kidney Disease, Stage 5",
        "Secondary Hyperparathyroidism"
      ],
      "interventions": [
        {
          "name": "Zemplar® injection",
          "type": "DRUG"
        },
        {
          "name": "Hectorol® injection",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Abbott",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "20 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "20 Years and older"
      },
      "enrollment_count": 41,
      "start_date": "2006-06",
      "completion_date": null,
      "has_results": true,
      "last_update_posted_date": "2009-12-24",
      "last_synced_at": "2026-06-10T12:25:16.703Z",
      "location_count": 2,
      "location_summary": "Bellevue, Nebraska • Omaha, Nebraska",
      "locations": [
        {
          "city": "Bellevue",
          "state": "Nebraska"
        },
        {
          "city": "Omaha",
          "state": "Nebraska"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00257920"
    },
    {
      "nct_id": "NCT02015780",
      "title": "Fasiglifam in Type 2 Diabetic Subjects With Chronic Kidney Disease Stage 4 or 5 on Hemodialysis",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Type 2 Diabetes Mellitus",
        "Chronic Kidney Disease"
      ],
      "interventions": [
        {
          "name": "Fasiglifam",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        },
        {
          "name": "Antihyperglycemic therapy",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Takeda",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 0,
      "start_date": "2013-12",
      "completion_date": "2016-01",
      "has_results": false,
      "last_update_posted_date": "2014-01-27",
      "last_synced_at": "2026-06-10T12:25:16.703Z",
      "location_count": 7,
      "location_summary": "Whittier, California • Westminster, Colorado • Tampa, Florida + 4 more",
      "locations": [
        {
          "city": "Whittier",
          "state": "California"
        },
        {
          "city": "Westminster",
          "state": "Colorado"
        },
        {
          "city": "Tampa",
          "state": "Florida"
        },
        {
          "city": "Rosedale",
          "state": "New York"
        },
        {
          "city": "Cincinnati",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02015780"
    },
    {
      "nct_id": "NCT01906489",
      "title": "20-Week Repeat Oral Dose Study of AKB-6548 in Participants With Chronic Kidney Disease and Anemia",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Anemia",
        "Chronic Kidney Disease"
      ],
      "interventions": [
        {
          "name": "AKB-6548",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Akebia Therapeutics",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "82 Years",
        "sex": "ALL",
        "summary": "18 Years to 82 Years"
      },
      "enrollment_count": 210,
      "start_date": "2013-07-23",
      "completion_date": "2014-09-03",
      "has_results": true,
      "last_update_posted_date": "2022-07-21",
      "last_synced_at": "2026-06-10T12:25:16.703Z",
      "location_count": 47,
      "location_summary": "Glendale, Arizona • Tucson, Arizona • Azusa, California + 44 more",
      "locations": [
        {
          "city": "Glendale",
          "state": "Arizona"
        },
        {
          "city": "Tucson",
          "state": "Arizona"
        },
        {
          "city": "Azusa",
          "state": "California"
        },
        {
          "city": "Chula Vista",
          "state": "California"
        },
        {
          "city": "Downey",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01906489"
    },
    {
      "nct_id": "NCT04087798",
      "title": "Controlling Hypertension Through Education and Coaching in Kidney Disease",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Chronic Kidney Diseases",
        "Chronic Disease",
        "Chronic Kidney Disease, Stage 3 (Moderate)",
        "Chronic Kidney Disease, Stage 4 (Severe)",
        "Chronic Kidney Disease Stage 5",
        "Hypertension"
      ],
      "interventions": [
        {
          "name": "Control-EDI",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Intervention-EDI",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Health coaching",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of Michigan",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "85 Years",
        "sex": "ALL",
        "summary": "21 Years to 85 Years"
      },
      "enrollment_count": 320,
      "start_date": "2020-02-04",
      "completion_date": "2025-12-03",
      "has_results": false,
      "last_update_posted_date": "2026-03-27",
      "last_synced_at": "2026-06-10T12:25:16.703Z",
      "location_count": 11,
      "location_summary": "Ann Arbor, Michigan • Brighton, Michigan • Canton, Michigan + 6 more",
      "locations": [
        {
          "city": "Ann Arbor",
          "state": "Michigan"
        },
        {
          "city": "Ann Arbor",
          "state": "Michigan"
        },
        {
          "city": "Brighton",
          "state": "Michigan"
        },
        {
          "city": "Canton",
          "state": "Michigan"
        },
        {
          "city": "Chelsea",
          "state": "Michigan"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04087798"
    },
    {
      "nct_id": "NCT02492620",
      "title": "Ferric Citrate for the Transition From CKD Stage 4/5 to CKD Stage 5D",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Chronic Kidney Disease",
        "Hyperphosphatemia",
        "Iron Deficiency Anemia",
        "Renal Insufficiency"
      ],
      "interventions": [
        {
          "name": "Ferric Citrate",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Denver Nephrologists, P.C.",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 200,
      "start_date": "2015-03",
      "completion_date": "2017-11",
      "has_results": false,
      "last_update_posted_date": "2018-08-01",
      "last_synced_at": "2026-06-10T12:25:16.703Z",
      "location_count": 1,
      "location_summary": "Denver, Colorado",
      "locations": [
        {
          "city": "Denver",
          "state": "Colorado"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02492620"
    },
    {
      "nct_id": "NCT07446296",
      "title": "Kidney Transplant Improvement Through New Exercise Training to Increase Capacity",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Chronic Kidney Disease 5D",
        "Chronic Kidney Disease Stage 5",
        "Kidney Failure",
        "Kidney Failure,Chronic",
        "Renal Insufficiency Chronic",
        "Chronic Kidney Disease Stage 4",
        "Kidney Transplantation",
        "Waiting List",
        "Transplant Candidate",
        "Exercise Theraphy"
      ],
      "interventions": [
        {
          "name": "Exercise Rehabilitation Program with Physical Activity Tracker",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Active control",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL",
        "OTHER"
      ],
      "sponsor": "University of Pennsylvania",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "60 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "60 Years and older"
      },
      "enrollment_count": 60,
      "start_date": "2026-03-24",
      "completion_date": "2028-05",
      "has_results": false,
      "last_update_posted_date": "2026-05-06",
      "last_synced_at": "2026-06-10T12:25:16.703Z",
      "location_count": 1,
      "location_summary": "Philadelphia, Pennsylvania",
      "locations": [
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07446296"
    },
    {
      "nct_id": "NCT04633304",
      "title": "A Single Arm sTudy to Evaluate the Effectiveness of EndoAVF in a Pre-dialysis Population (STEP Study)",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "CKD Stage 3",
        "CKD Stage 4",
        "CKD Stage 5"
      ],
      "interventions": [
        {
          "name": "EndoAVF System for endovascular AV fistula creation",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "California Institute of Renal Research",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 30,
      "start_date": "2020-12-15",
      "completion_date": "2023-12-31",
      "has_results": false,
      "last_update_posted_date": "2023-02-09",
      "last_synced_at": "2026-06-10T12:25:16.703Z",
      "location_count": 1,
      "location_summary": "Escondido, California",
      "locations": [
        {
          "city": "Escondido",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04633304"
    }
  ]
}