{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Chronic+Lower+Limb+Pain&page=3",
    "query": {
      "condition": "Chronic Lower Limb Pain",
      "page": 3
    },
    "page_size": 10
  },
  "pagination": {
    "page": 3,
    "page_size": 10,
    "total_count": 81,
    "total_pages": 9,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Chronic+Lower+Limb+Pain&page=4&page_size=10",
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Chronic+Lower+Limb+Pain&page=2&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-10-03T22:53:32.226Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT02757378",
      "title": "Manual Therapy as a Form of Sensory Discrimination in Chronic Low Back Pain",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Low Back Pain"
      ],
      "interventions": [
        {
          "name": "Neuroplasticity Explanation (Experimental)",
          "type": "PROCEDURE"
        },
        {
          "name": "Biomechanical Explanation (Control)",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Kevin Farrell",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 62,
      "start_date": "2015-05",
      "completion_date": "2015-09",
      "has_results": false,
      "last_update_posted_date": "2016-05-02",
      "last_synced_at": "2026-10-03T22:53:32.226Z",
      "location_count": 5,
      "location_summary": "Moline, Illinois • Silvis, Illinois • Woodridge, Illinois + 1 more",
      "locations": [
        {
          "city": "Moline",
          "state": "Illinois"
        },
        {
          "city": "Silvis",
          "state": "Illinois"
        },
        {
          "city": "Woodridge",
          "state": "Illinois"
        },
        {
          "city": "Davenport",
          "state": "Iowa"
        },
        {
          "city": "Davenport",
          "state": "Iowa"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02757378"
    },
    {
      "nct_id": "NCT02646579",
      "title": "Effects of Dry Needling Using Spinal and Peripheral Sites Versus Peripheral Sites Only",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Plantar Fasciitis",
        "Achilles Tendinitis",
        "Patellofemoral Pain Syndrome"
      ],
      "interventions": [
        {
          "name": "Spinal and Peripheral Dry Needling",
          "type": "PROCEDURE"
        },
        {
          "name": "Peripheral Dry Needling",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Emory University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 34,
      "start_date": "2017-10-27",
      "completion_date": "2019-05-01",
      "has_results": false,
      "last_update_posted_date": "2019-07-18",
      "last_synced_at": "2026-10-03T22:53:32.226Z",
      "location_count": 1,
      "location_summary": "Atlanta, Georgia",
      "locations": [
        {
          "city": "Atlanta",
          "state": "Georgia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02646579"
    },
    {
      "nct_id": "NCT00370799",
      "title": "Effectiveness of Caudal Epidural Injections in Treatment of Chronic Low Back and Lower Extremity Pain",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "EARLY_PHASE1"
      ],
      "conditions": [
        "Low Back Pain"
      ],
      "interventions": [
        {
          "name": "Caudal epidural injection",
          "type": "DRUG"
        },
        {
          "name": "Caudal Epidural Injection with generic Celestone",
          "type": "DRUG"
        },
        {
          "name": "Caudal Epidural Injection with Celestone",
          "type": "DRUG"
        },
        {
          "name": "Caudal Epidural Injection with DepoMedrol",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Pain Management Center of Paducah",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 240,
      "start_date": "2007-01",
      "completion_date": "2010-03",
      "has_results": false,
      "last_update_posted_date": "2013-08-16",
      "last_synced_at": "2026-10-03T22:53:32.226Z",
      "location_count": 1,
      "location_summary": "Paducah, Kentucky",
      "locations": [
        {
          "city": "Paducah",
          "state": "Kentucky"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00370799"
    },
    {
      "nct_id": "NCT05022121",
      "title": "Integrated Supported Biopsychosocial Self-Management for Back Related Leg Pain",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Low Back Pain",
        "Sciatica",
        "Back Related Leg Pain",
        "Pain, Chronic",
        "Intervertebral Disc Displacement"
      ],
      "interventions": [
        {
          "name": "Supported Biopsychosocial Self-Management (SBSM)",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Medical Care",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL",
        "DRUG"
      ],
      "sponsor": "University of Minnesota",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 42,
      "start_date": "2022-01-26",
      "completion_date": "2023-02-20",
      "has_results": true,
      "last_update_posted_date": "2024-03-15",
      "last_synced_at": "2026-10-03T22:53:32.226Z",
      "location_count": 2,
      "location_summary": "Minneapolis, Minnesota • Pittsburgh, Pennsylvania",
      "locations": [
        {
          "city": "Minneapolis",
          "state": "Minnesota"
        },
        {
          "city": "Pittsburgh",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05022121"
    },
    {
      "nct_id": "NCT00058968",
      "title": "A Study for the Treatment of Painful Diabetic Neuropathy",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Diabetic Neuropathy, Painful"
      ],
      "interventions": [
        {
          "name": "Duloxetine hydrochloride",
          "type": "DRUG"
        },
        {
          "name": "placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Eli Lilly and Company",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 660,
      "start_date": "2002-10",
      "completion_date": "2005-03",
      "has_results": false,
      "last_update_posted_date": "2007-05-17",
      "last_synced_at": "2026-10-03T22:53:32.226Z",
      "location_count": 1,
      "location_summary": "Pembroke Pines, Florida",
      "locations": [
        {
          "city": "Pembroke Pines",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00058968"
    },
    {
      "nct_id": "NCT00386724",
      "title": "Effectiveness of Precision Spinal Cord Stimulation With Artisan Paddle Electrode",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Back Pain",
        "Chronic Pain",
        "Pain in Leg, Unspecified"
      ],
      "interventions": [
        {
          "name": "Precision Spinal Cord Stimulation System",
          "type": "DEVICE"
        },
        {
          "name": "Artisan Surgical Lead",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Boston Scientific Corporation",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 8,
      "start_date": "2006-10",
      "completion_date": "2008-08",
      "has_results": true,
      "last_update_posted_date": "2020-12-17",
      "last_synced_at": "2026-10-03T22:53:32.226Z",
      "location_count": 2,
      "location_summary": "Charleston, South Carolina • Norfolk, Virginia",
      "locations": [
        {
          "city": "Charleston",
          "state": "South Carolina"
        },
        {
          "city": "Norfolk",
          "state": "Virginia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00386724"
    },
    {
      "nct_id": "NCT01976598",
      "title": "Sub-Sensory Intraspinal Neurostimulation Therapy",
      "overall_status": "TERMINATED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Back Pain",
        "Back Pain With Radiation",
        "Pain in Leg, Unspecified"
      ],
      "interventions": [
        {
          "name": "Sub-Sensory Stimulation",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Algos Clinical Development Thomas L. Yearwood, MD, PhD",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "22 Years",
        "maximum_age": "85 Years",
        "sex": "ALL",
        "summary": "22 Years to 85 Years"
      },
      "enrollment_count": 1,
      "start_date": "2013-10",
      "completion_date": "2015-01",
      "has_results": false,
      "last_update_posted_date": "2015-01-19",
      "last_synced_at": "2026-10-03T22:53:32.226Z",
      "location_count": 1,
      "location_summary": "Pascagoula, Mississippi",
      "locations": [
        {
          "city": "Pascagoula",
          "state": "Mississippi"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01976598"
    },
    {
      "nct_id": "NCT03251937",
      "title": "Value of Multiple Modalities Using the Spectra WaveWriter Spinal Cord Stimulator System",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Chronic Pain",
        "Back Pain"
      ],
      "interventions": [
        {
          "name": "Spectra WaveWriter SCS System",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Boston Scientific Corporation",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "22 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "22 Years and older"
      },
      "enrollment_count": 97,
      "start_date": "2018-01-09",
      "completion_date": "2020-03-10",
      "has_results": true,
      "last_update_posted_date": "2021-04-01",
      "last_synced_at": "2026-10-03T22:53:32.226Z",
      "location_count": 15,
      "location_summary": "Napa, California • Jupiter, Florida • Ocala, Florida + 12 more",
      "locations": [
        {
          "city": "Napa",
          "state": "California"
        },
        {
          "city": "Jupiter",
          "state": "Florida"
        },
        {
          "city": "Ocala",
          "state": "Florida"
        },
        {
          "city": "Ypsilanti",
          "state": "Michigan"
        },
        {
          "city": "Springfield",
          "state": "Missouri"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03251937"
    },
    {
      "nct_id": "NCT04319887",
      "title": "ECAP-controlled, Closed-loop Stimulation to Treat Chronic Trunk and/or Limb Pain (ECAP)",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Chronic Pain",
        "Back Pain",
        "Pain"
      ],
      "interventions": [
        {
          "name": "Evoke Spinal Cord Stimulation (SCS) System",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Saluda Medical Pty Ltd",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 300,
      "start_date": "2020-10-29",
      "completion_date": "2023-12-28",
      "has_results": true,
      "last_update_posted_date": "2024-12-31",
      "last_synced_at": "2026-10-03T22:53:32.226Z",
      "location_count": 22,
      "location_summary": "Little Rock, Arkansas • Carlsbad, California • Santa Rosa, California + 18 more",
      "locations": [
        {
          "city": "Little Rock",
          "state": "Arkansas"
        },
        {
          "city": "Carlsbad",
          "state": "California"
        },
        {
          "city": "Santa Rosa",
          "state": "California"
        },
        {
          "city": "Gainesville",
          "state": "Florida"
        },
        {
          "city": "Atlanta",
          "state": "Georgia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04319887"
    },
    {
      "nct_id": "NCT00681447",
      "title": "Treatment of Chronic Low Back and Lower Extremity Pain",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Low Back Pain"
      ],
      "interventions": [
        {
          "name": "Lumbar Interlaminar Epidural",
          "type": "PROCEDURE"
        },
        {
          "name": "Lumbar Interlaminar Epidural injection",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Pain Management Center of Paducah",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 120,
      "start_date": "2008-02",
      "completion_date": "2014-12",
      "has_results": false,
      "last_update_posted_date": "2015-10-21",
      "last_synced_at": "2026-10-03T22:53:32.226Z",
      "location_count": 1,
      "location_summary": "Paducah, Kentucky",
      "locations": [
        {
          "city": "Paducah",
          "state": "Kentucky"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00681447"
    }
  ]
}