{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Chronic+Lower+Limb+Pain&page=4",
    "query": {
      "condition": "Chronic Lower Limb Pain",
      "page": 4
    },
    "page_size": 10
  },
  "pagination": {
    "page": 4,
    "page_size": 10,
    "total_count": 81,
    "total_pages": 9,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Chronic+Lower+Limb+Pain&page=5&page_size=10",
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Chronic+Lower+Limb+Pain&page=3&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-10-05T06:10:29.524Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT07190807",
      "title": "Managing Pain Using Optimized Sequences by Adjusting Parameters With Independent Current Control",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Chronic Pain",
        "Intractable Pain",
        "Low Back Pain",
        "Chronic Low-back Pain",
        "Chronic Leg Pain",
        "Leg Pain"
      ],
      "interventions": [
        {
          "name": "Boston Scientific WaveWriter Alpha™ SCS Systems",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Boston Scientific Corporation",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 70,
      "start_date": "2025-11-07",
      "completion_date": "2029-05",
      "has_results": false,
      "last_update_posted_date": "2026-09-03",
      "last_synced_at": "2026-10-05T06:10:29.524Z",
      "location_count": 7,
      "location_summary": "Greenwood, Colorado • Clermont, Florida • New Orleans, Louisiana + 4 more",
      "locations": [
        {
          "city": "Greenwood",
          "state": "Colorado"
        },
        {
          "city": "Clermont",
          "state": "Florida"
        },
        {
          "city": "New Orleans",
          "state": "Louisiana"
        },
        {
          "city": "The Bronx",
          "state": "New York"
        },
        {
          "city": "Trevose",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07190807"
    },
    {
      "nct_id": "NCT05880251",
      "title": "Operant Conditioning of Sensory Brain Responses to Reduce Phantom Limb Pain in People With Limb Amputation",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Phantom Limb Pain After Amputation",
        "Lower Limb Amputation",
        "Upper Limb Amputation",
        "Phantom Pain",
        "Chronic Pain"
      ],
      "interventions": [
        {
          "name": "Operant Conditioning with Peripheral Stimulation",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Control Group with Peripheral Stimulation Only",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "VA Office of Research and Development",
      "sponsor_class": "FED",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 20,
      "start_date": "2023-07-01",
      "completion_date": "2025-08-29",
      "has_results": false,
      "last_update_posted_date": "2026-01-16",
      "last_synced_at": "2026-10-05T06:10:29.524Z",
      "location_count": 1,
      "location_summary": "Albany, New York",
      "locations": [
        {
          "city": "Albany",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05880251"
    },
    {
      "nct_id": "NCT00732394",
      "title": "A Comparative Study: Non-Surgical Spinal Decompression and Spinal Manipulative Therapy- Utilizing a Quantifiable Musculoskeletal Functional Assessment Risk Analysis Tool (MSDR®) in Patients With Chronic Low Back Pain",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Chronic Low Back Pain"
      ],
      "interventions": [
        {
          "name": "MSDR",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "MedAppraise, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 200,
      "start_date": "2008-08",
      "completion_date": "2010-01",
      "has_results": false,
      "last_update_posted_date": "2008-08-12",
      "last_synced_at": "2026-10-05T06:10:29.524Z",
      "location_count": 1,
      "location_summary": "Clearwater, Florida",
      "locations": [
        {
          "city": "Clearwater",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00732394"
    },
    {
      "nct_id": "NCT04543227",
      "title": "Opioid Laws and Pediatric Use",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Burns",
        "Knee Injuries",
        "Opioid Use",
        "Pain"
      ],
      "interventions": [
        {
          "name": "Opioid Use 90-Days Post Treatment",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Nationwide Children's Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "0 Years",
        "maximum_age": "18 Years",
        "sex": "ALL",
        "summary": "0 Years to 18 Years"
      },
      "enrollment_count": 980,
      "start_date": "2020-09-10",
      "completion_date": "2023-11-16",
      "has_results": false,
      "last_update_posted_date": "2024-04-30",
      "last_synced_at": "2026-10-05T06:10:29.524Z",
      "location_count": 1,
      "location_summary": "Columbus, Ohio",
      "locations": [
        {
          "city": "Columbus",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04543227"
    },
    {
      "nct_id": "NCT03532230",
      "title": "Cost Effectiveness of OMT for Chronic Low Back Pain",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Lumbar Radiculopathy",
        "Lesion of Sciatic Nerve, Left Lower Limb",
        "Lesion of Sciatic Nerve, Right Lower Limb",
        "Lumbar Spinal Stenosis",
        "Lumbar Spondylosis",
        "Lumbago With Sciatica, Left Side",
        "Lumbago With Sciatica, Right Side"
      ],
      "interventions": [
        {
          "name": "Osteopathic Manipulative Treatment (OMT)",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Rowan University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "84 Years",
        "sex": "ALL",
        "summary": "18 Years to 84 Years"
      },
      "enrollment_count": 146,
      "start_date": "2019-03-22",
      "completion_date": "2020-02-28",
      "has_results": false,
      "last_update_posted_date": "2020-05-04",
      "last_synced_at": "2026-10-05T06:10:29.524Z",
      "location_count": 3,
      "location_summary": "East Lansing, Michigan • Stratford, New Jersey • Voorhees Township, New Jersey",
      "locations": [
        {
          "city": "East Lansing",
          "state": "Michigan"
        },
        {
          "city": "Stratford",
          "state": "New Jersey"
        },
        {
          "city": "Voorhees Township",
          "state": "New Jersey"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03532230"
    },
    {
      "nct_id": "NCT01547364",
      "title": "Caudal Epidural Injection of Dextrose For Low Back Pain",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Back Pain Lower Back Chronic"
      ],
      "interventions": [
        {
          "name": "Saline",
          "type": "DRUG"
        },
        {
          "name": "Dextrose",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Smigel, Liza, M.D.",
      "sponsor_class": "INDIV",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "18 Years to 75 Years"
      },
      "enrollment_count": 35,
      "start_date": "2012-02",
      "completion_date": "2015-11",
      "has_results": false,
      "last_update_posted_date": "2018-04-30",
      "last_synced_at": "2026-10-05T06:10:29.524Z",
      "location_count": 1,
      "location_summary": "Hilo, Hawaii",
      "locations": [
        {
          "city": "Hilo",
          "state": "Hawaii"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01547364"
    },
    {
      "nct_id": "NCT03922139",
      "title": "Botox for the Treatment of Chronic Exertional Compartment Syndrome",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1",
        "PHASE2"
      ],
      "conditions": [
        "Compartment Syndrome of Leg"
      ],
      "interventions": [
        {
          "name": "OnabotulinumtoxinA Injection",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of Wisconsin, Madison",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 7,
      "start_date": "2019-10-08",
      "completion_date": "2021-12-15",
      "has_results": true,
      "last_update_posted_date": "2023-02-14",
      "last_synced_at": "2026-10-05T06:10:29.524Z",
      "location_count": 1,
      "location_summary": "Madison, Wisconsin",
      "locations": [
        {
          "city": "Madison",
          "state": "Wisconsin"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03922139"
    },
    {
      "nct_id": "NCT02997644",
      "title": "Impact of Different Educational Approaches on Post-operative Opiate Utilization After Elective Lower Extremity Surgery",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Knee Injuries and Disorders",
        "Hip Injuries and Disorders",
        "Opiate Addiction"
      ],
      "interventions": [
        {
          "name": "Video Education",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Usual Care Group",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Brooke Army Medical Center",
      "sponsor_class": "FED",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 120,
      "start_date": "2016-06",
      "completion_date": "2019-09-01",
      "has_results": false,
      "last_update_posted_date": "2020-01-18",
      "last_synced_at": "2026-10-05T06:10:29.524Z",
      "location_count": 1,
      "location_summary": "San Antonio, Texas",
      "locations": [
        {
          "city": "San Antonio",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02997644"
    },
    {
      "nct_id": "NCT03761277",
      "title": "Embrace TDD: Post-Market Study to Evaluate Intrathecal Morphine as an Alternative to Systemic Opioids for Chronic Pain",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Chronic Non-malignant Pain",
        "Chronic Pain",
        "Pain, Back",
        "Pain, Leg"
      ],
      "interventions": [
        {
          "name": "Medtronic SynchroMed™ II infusion system",
          "type": "DEVICE"
        },
        {
          "name": "Preservative-free morphine sulfate (PFMS)",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "DRUG"
      ],
      "sponsor": "MedtronicNeuro",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 93,
      "start_date": "2019-01-16",
      "completion_date": "2021-12-06",
      "has_results": true,
      "last_update_posted_date": "2023-02-08",
      "last_synced_at": "2026-10-05T06:10:29.524Z",
      "location_count": 16,
      "location_summary": "Anchorage, Alaska • Carlsbad, California • Napa, California + 13 more",
      "locations": [
        {
          "city": "Anchorage",
          "state": "Alaska"
        },
        {
          "city": "Carlsbad",
          "state": "California"
        },
        {
          "city": "Napa",
          "state": "California"
        },
        {
          "city": "Merritt Island",
          "state": "Florida"
        },
        {
          "city": "Cape Girardeau",
          "state": "Missouri"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03761277"
    },
    {
      "nct_id": "NCT00516308",
      "title": "A Non-Randomized Study of the NightHawk Peripheral Plaque Excision System During Plaque Excision of Peripheral Arterial Disease",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Peripheral Vascular Diseases"
      ],
      "interventions": [
        {
          "name": "NightHawk",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "FoxHollow Technologies",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 100,
      "start_date": "2007-08",
      "completion_date": "2007-12",
      "has_results": false,
      "last_update_posted_date": "2008-01-18",
      "last_synced_at": "2026-10-05T06:10:29.524Z",
      "location_count": 1,
      "location_summary": "Austin, Texas",
      "locations": [
        {
          "city": "Austin",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00516308"
    }
  ]
}