{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Chronic+Migraine%2C+Headaches&page=7", "query": { "condition": "Chronic Migraine, Headaches", "page": 7 }, "page_size": 10 }, "pagination": { "page": 7, "page_size": 10, "total_count": 154, "total_pages": 16, "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Chronic+Migraine%2C+Headaches&page=8&page_size=10", "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Chronic+Migraine%2C+Headaches&page=6&page_size=10" }, "source": "remote", "last_synced_at": "2026-10-11T01:29:13.204Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT05679908", "title": "A Study to Evaluate the Efficacy and Safety of TNX-1900 in Patients With Chronic Migraine", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Chronic Migraine", "Chronic Migraine, Headache", "Chronic Migraine Without Aura", "Aura Migraine" ], "interventions": [ { "name": "TNX-1900", "type": "DRUG" }, { "name": "Placebo Nasal Spray", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Tonix Pharmaceuticals, Inc.", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "65 Years", "sex": "ALL", "summary": "18 Years to 65 Years" }, "enrollment_count": 88, "start_date": "2022-12-06", "completion_date": "2023-10-23", "has_results": true, "last_update_posted_date": "2025-02-25", "last_synced_at": "2026-10-11T01:29:13.204Z", "location_count": 26, "location_summary": "Little Rock, Arkansas • Lemon Grove, California • Oceanside, California + 23 more", "locations": [ { "city": "Little Rock", "state": "Arkansas" }, { "city": "Lemon Grove", "state": "California" }, { "city": "Oceanside", "state": "California" }, { "city": "Temecula", "state": "California" }, { "city": "Jacksonville", "state": "Florida" } ], "official_url": "https://clinicaltrials.gov/study/NCT05679908" }, { "nct_id": "NCT04260087", "title": "New Daily Persistent Headache Biomarkers Study", "overall_status": "TERMINATED", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "New Daily Persistent Headache", "New Daily Persistent Headache (NDPH)" ], "interventions": [], "intervention_types": [], "sponsor": "Albert Einstein College of Medicine", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "75 Years", "sex": "ALL", "summary": "18 Years to 75 Years" }, "enrollment_count": 8, "start_date": "2018-05-01", "completion_date": "2021-11-18", "has_results": false, "last_update_posted_date": "2022-03-03", "last_synced_at": "2026-10-11T01:29:13.204Z", "location_count": 1, "location_summary": "The Bronx, New York", "locations": [ { "city": "The Bronx", "state": "New York" } ], "official_url": "https://clinicaltrials.gov/study/NCT04260087" }, { "nct_id": "NCT05752396", "title": "Overlapping Pain Trajectory Study", "overall_status": "RECRUITING", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Migraine", "Musculoskeletal Pain", "Functional Abdominal Pain Disorders", "Chronic Pain", "Widespread Chronic Pain", "Low Back Pain", "Healthy Volunteers" ], "interventions": [ { "name": "Conditioned Pain Modulation", "type": "OTHER" }, { "name": "Offset Analgesia", "type": "OTHER" }, { "name": "Spatial Summation", "type": "OTHER" }, { "name": "Temporal Summation", "type": "OTHER" } ], "intervention_types": [ "OTHER" ], "sponsor": "Children's Hospital Medical Center, Cincinnati", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "10 Years", "maximum_age": "19 Years", "sex": "ALL", "summary": "10 Years to 19 Years" }, "enrollment_count": 420, "start_date": "2023-03-01", "completion_date": "2028-07-01", "has_results": false, "last_update_posted_date": "2024-08-22", "last_synced_at": "2026-10-11T01:29:13.204Z", "location_count": 1, "location_summary": "Cincinnati, Ohio", "locations": [ { "city": "Cincinnati", "state": "Ohio" } ], "official_url": "https://clinicaltrials.gov/study/NCT05752396" }, { "nct_id": "NCT05814497", "title": "Supraspinal Processing of Sensory Aspects of Pain", "overall_status": "RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Migraine in Children", "Complex Regional Pain Syndromes", "Musculoskeletal Pain", "Functional Abdominal Pain Syndrome", "Fibromyalgia" ], "interventions": [ { "name": "Multisensory Task", "type": "OTHER" }, { "name": "Graphesthesia", "type": "OTHER" }, { "name": "Divided attention", "type": "OTHER" } ], "intervention_types": [ "OTHER" ], "sponsor": "Children's Hospital Medical Center, Cincinnati", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "10 Years", "maximum_age": "17 Years", "sex": "ALL", "summary": "10 Years to 17 Years" }, "enrollment_count": 255, "start_date": "2023-05-01", "completion_date": "2027-06-30", "has_results": false, "last_update_posted_date": "2026-06-05", "last_synced_at": "2026-10-11T01:29:13.204Z", "location_count": 1, "location_summary": "Cincinnati, Ohio", "locations": [ { "city": "Cincinnati", "state": "Ohio" } ], "official_url": "https://clinicaltrials.gov/study/NCT05814497" }, { "nct_id": "NCT06862674", "title": "Clinical Exploration of NEUROMARK System in Participants With Chronic Migraine", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Chronic Migraine Headache" ], "interventions": [ { "name": "NEUROMARK System", "type": "DEVICE" } ], "intervention_types": [ "DEVICE" ], "sponsor": "Neurent Medical", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 24, "start_date": "2024-09-06", "completion_date": "2026-01-21", "has_results": false, "last_update_posted_date": "2026-09-16", "last_synced_at": "2026-10-11T01:29:13.204Z", "location_count": 7, "location_summary": "Birmingham, Alabama • Opelika, Alabama • Los Angeles, California + 4 more", "locations": [ { "city": "Birmingham", "state": "Alabama" }, { "city": "Opelika", "state": "Alabama" }, { "city": "Los Angeles", "state": "California" }, { "city": "Sacramento", "state": "California" }, { "city": "San Diego", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT06862674" }, { "nct_id": "NCT07616128", "title": "Study of EVO756 in Adults With Migraine", "overall_status": "RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Migraine" ], "interventions": [ { "name": "EVO756, Dose 1", "type": "DRUG" }, { "name": "EVO756, Dose 2", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Evommune, Inc.", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "64 Years", "sex": "ALL", "summary": "18 Years to 64 Years" }, "enrollment_count": 330, "start_date": "2026-07-29", "completion_date": "2027-11", "has_results": false, "last_update_posted_date": "2026-10-02", "last_synced_at": "2026-10-11T01:29:13.204Z", "location_count": 33, "location_summary": "Chandler, Arizona • Buena Park, California • Fresno, California + 27 more", "locations": [ { "city": "Chandler", "state": "Arizona" }, { "city": "Buena Park", "state": "California" }, { "city": "Fresno", "state": "California" }, { "city": "Los Angeles", "state": "California" }, { "city": "Walnut Creek", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT07616128" }, { "nct_id": "NCT04031469", "title": "A Non-Interventional Pilot Study to Explore the Role of Gut Flora in Disease", "overall_status": "SUSPENDED", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Gut Microbiome", "Gastrointestinal Microbiome", "Autism", "Autism Spectrum Disorder", "Autism Spectrum Disorder High-Functioning", "Alzheimer Disease", "Alzheimer Dementia (AD)", "Alzheimer Dementia", "Alzheimer Disease (AD)", "Crohn", "Crohn Colitis", "Crohn Disease (CD)", "Crohn Disease Colon", "Myalgic Encephalomyelitis", "ME/CFS", "Myalgic Encephalomyelitis (ME)", "Myalgic Encephalomyelitis/Chronic Fatigue Syndrome", "Psoriasis", "Psoriasis Annularis", "Psoriasis Chronic", "Chronic Urinary Tract Infection", "Ulcerative Colitis (Disorder)", "Ulcerative Colitis (UC)", "Ulcerative Colitis Acute", "Ulcerative Colitis Chronic", "Multiple Sclerosis", "Multiple Sclerosis (MS) - Relapsing-remitting", "Multiple Sclerosis (MS) Primary Progressive", "Constipation Chronic Idiopathic", "Constipation", "Celiac", "Celiac Disease", "Celiac Sprue", "Lyme Arthritis", "Lyme Borreliosis, Nervous System", "Lyme Disease, Chronic", "Cholesterol", "Cholesterol Level, High", "Cancer", "Colon Cancer", "Amyotrophic Lateral Sclerosis (ALS)", "Amyotrophic Lateral Sclerosis", "Rheumatoid Arthritis (RA)", "Rheumatoid Arthritis - Rheumatism", "Chronic Fatigue Syndrome (CFS)", "PARKINSON DISEASE (Disorder)", "Parkinson Disease", "Parkinson Disease (PD)", "Depression", "Major Depressive Disorder (MDD)", "Depression Disorder", "Depression in Adults", "Anxiety", "Anxiety Disorder Generalized", "Obsessive Compulsive Disorder (OCD)", "Obsessive Compulsive Disorder OCD", "Obsessive - Compulsive Disorder", "Bipolar", "Bipolar 1 Disorder", "Bipolar Disorder (BD)", "Bipolar Disorder I and II", "Bipolar and Related Disorders", "Migraine", "Migraine Disorder", "Diabetes (DM)", "Diabetes", "Lupus", "Lupus Erythematosus", "Epidermolysis Bullosa (EB)", "Mesothelioma", "Mesothelioma Malignant", "IBS (Irritable Bowel Syndrome)", "Irritable Bowel", "IBS - Irritable Bowel Syndrome", "Irritable Bowel Syndrome (IBS)", "Eczema", "Eczema Atopic Dermatitis", "Acne", "Myasthaenia Gravis", "Gout" ], "interventions": [ { "name": "There is no intervention in this study", "type": "OTHER" } ], "intervention_types": [ "OTHER" ], "sponsor": "ProgenaBiome", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "12 Years", "maximum_age": null, "sex": "ALL", "summary": "12 Years and older" }, "enrollment_count": 1000, "start_date": "2019-07-11", "completion_date": "2030-12-10", "has_results": false, "last_update_posted_date": "2026-09-21", "last_synced_at": "2026-10-11T01:29:13.204Z", "location_count": 1, "location_summary": "Ventura, California", "locations": [ { "city": "Ventura", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT04031469" }, { "nct_id": "NCT00868556", "title": "fMRI of the Brainstem in Migraine Sufferers and Controls. Does Iron Deposition Correlate With Progression of Disease?", "overall_status": "COMPLETED", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Episodic Migraine", "Chronic Daily Migraine" ], "interventions": [], "intervention_types": [], "sponsor": "The Cleveland Clinic", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 33, "start_date": "2009-01", "completion_date": "2009-08", "has_results": false, "last_update_posted_date": "2010-01-05", "last_synced_at": "2026-10-11T01:29:13.204Z", "location_count": 1, "location_summary": "Cleveland, Ohio", "locations": [ { "city": "Cleveland", "state": "Ohio" } ], "official_url": "https://clinicaltrials.gov/study/NCT00868556" }, { "nct_id": "NCT06047444", "title": "A Study to Evaluate the Effectiveness and Safety of Dysport® for the Prevention of Chronic Migraine in Adults", "overall_status": "ACTIVE_NOT_RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Chronic Migraine" ], "interventions": [ { "name": "Botulinum toxin type A", "type": "BIOLOGICAL" }, { "name": "Placebo", "type": "OTHER" } ], "intervention_types": [ "BIOLOGICAL", "OTHER" ], "sponsor": "Ipsen", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 759, "start_date": "2023-10-12", "completion_date": "2026-11-12", "has_results": false, "last_update_posted_date": "2026-09-04", "last_synced_at": "2026-10-11T01:29:13.204Z", "location_count": 72, "location_summary": "Birmingham, Alabama • Phoenix, Arizona • Scottsdale, Arizona + 61 more", "locations": [ { "city": "Birmingham", "state": "Alabama" }, { "city": "Phoenix", "state": "Arizona" }, { "city": "Scottsdale", "state": "Arizona" }, { "city": "Canoga Park", "state": "California" }, { "city": "Colton", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT06047444" }, { "nct_id": "NCT01516892", "title": "A Long-term Efficacy, Safety, and Tolerability Study of BOTOX® in Patients With Chronic Migraine", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Migraine Disorders" ], "interventions": [ { "name": "onabotulinumtoxinA", "type": "BIOLOGICAL" } ], "intervention_types": [ "BIOLOGICAL" ], "sponsor": "Allergan", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 716, "start_date": "2011-12", "completion_date": "2015-11", "has_results": true, "last_update_posted_date": "2017-01-06", "last_synced_at": "2026-10-11T01:29:13.204Z", "location_count": 21, "location_summary": "Scottsdale, Arizona • Encinitas, California • Los Angeles, California + 18 more", "locations": [ { "city": "Scottsdale", "state": "Arizona" }, { "city": "Encinitas", "state": "California" }, { "city": "Los Angeles", "state": "California" }, { "city": "San Francisco", "state": "California" }, { "city": "Santa Monica", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT01516892" } ] }