{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Chronic+Migraine+Headache&page=5",
    "query": {
      "condition": "Chronic Migraine Headache",
      "page": 5
    },
    "page_size": 10
  },
  "pagination": {
    "page": 5,
    "page_size": 10,
    "total_count": 155,
    "total_pages": 16,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Chronic+Migraine+Headache&page=6&page_size=10",
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Chronic+Migraine+Headache&page=4&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-10-06T02:43:03.375Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT05769348",
      "title": "Investigation and Modulation of the Central Mu-Opioid Mechanism in Migraine (in Vivo)",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Chronic Migraine"
      ],
      "interventions": [
        {
          "name": "HD-tDCS Active Protocol",
          "type": "DEVICE"
        },
        {
          "name": "HD-tDCS Sham Protocol",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "University of Michigan",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 80,
      "start_date": "2023-01-26",
      "completion_date": "2026-12-30",
      "has_results": false,
      "last_update_posted_date": "2026-02-25",
      "last_synced_at": "2026-10-06T02:43:03.375Z",
      "location_count": 1,
      "location_summary": "Ann Arbor, Michigan",
      "locations": [
        {
          "city": "Ann Arbor",
          "state": "Michigan"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05769348"
    },
    {
      "nct_id": "NCT00810368",
      "title": "Treatment Study of Carnosine Versus Placebo in Gulf War Illness (GWI)",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Persian Gulf Syndrome"
      ],
      "interventions": [
        {
          "name": "Carnosine",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Georgetown University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "34 Years",
        "maximum_age": "82 Years",
        "sex": "ALL",
        "summary": "34 Years to 82 Years"
      },
      "enrollment_count": 33,
      "start_date": "2008-08",
      "completion_date": "2012-07",
      "has_results": true,
      "last_update_posted_date": "2019-06-28",
      "last_synced_at": "2026-10-06T02:43:03.375Z",
      "location_count": 1,
      "location_summary": "Washington D.C., District of Columbia",
      "locations": [
        {
          "city": "Washington D.C.",
          "state": "District of Columbia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00810368"
    },
    {
      "nct_id": "NCT02191579",
      "title": "Efficacy and Safety Study of BOTOX® Compared to Topiramate for the Prevention of Chronic Migraine in Adults",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Migraine Disorders"
      ],
      "interventions": [
        {
          "name": "onabotulinumtoxinA",
          "type": "BIOLOGICAL"
        },
        {
          "name": "Topiramate",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "BIOLOGICAL",
        "DRUG"
      ],
      "sponsor": "Allergan",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 282,
      "start_date": "2014-08-05",
      "completion_date": "2017-09-01",
      "has_results": true,
      "last_update_posted_date": "2018-06-07",
      "last_synced_at": "2026-10-06T02:43:03.375Z",
      "location_count": 32,
      "location_summary": "Phoenix, Arizona • Encinitas, California • Fresno, California + 28 more",
      "locations": [
        {
          "city": "Phoenix",
          "state": "Arizona"
        },
        {
          "city": "Encinitas",
          "state": "California"
        },
        {
          "city": "Fresno",
          "state": "California"
        },
        {
          "city": "Newport Beach",
          "state": "California"
        },
        {
          "city": "Denver",
          "state": "Colorado"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02191579"
    },
    {
      "nct_id": "NCT04349176",
      "title": "Onabotulinum Dose Comparison in Chronic Migraine Superior to 100 Units?",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Chronic Migraine, Headache"
      ],
      "interventions": [
        {
          "name": "Dose",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "United States Naval Medical Center, San Diego",
      "sponsor_class": "FED",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 35,
      "start_date": "2017-05-12",
      "completion_date": "2022-12-31",
      "has_results": false,
      "last_update_posted_date": "2024-02-05",
      "last_synced_at": "2026-10-06T02:43:03.375Z",
      "location_count": 1,
      "location_summary": "San Diego, California",
      "locations": [
        {
          "city": "San Diego",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04349176"
    },
    {
      "nct_id": "NCT01314651",
      "title": "Efficacy of Behavioral Insomnia Treatment for Chronic Migraine",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Chronic Migraine",
        "Insomnia"
      ],
      "interventions": [
        {
          "name": "Stimulus Control and Sleep Restriction",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Lifestyle Modification",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Daniel Riche",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 31,
      "start_date": "2011-03",
      "completion_date": "2013-12",
      "has_results": false,
      "last_update_posted_date": "2014-04-24",
      "last_synced_at": "2026-10-06T02:43:03.375Z",
      "location_count": 1,
      "location_summary": "University, Mississippi",
      "locations": [
        {
          "city": "University",
          "state": "Mississippi"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01314651"
    },
    {
      "nct_id": "NCT04965675",
      "title": "A Study With Eptinezumab in Adolescents (12-17 Years) With Chronic Migraine",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Chronic Migraine in Children"
      ],
      "interventions": [
        {
          "name": "Eptinezumab",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "H. Lundbeck A/S",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "12 Years",
        "maximum_age": "17 Years",
        "sex": "ALL",
        "summary": "12 Years to 17 Years"
      },
      "enrollment_count": 285,
      "start_date": "2021-06-30",
      "completion_date": "2026-10-31",
      "has_results": false,
      "last_update_posted_date": "2026-08-21",
      "last_synced_at": "2026-10-06T02:43:03.375Z",
      "location_count": 22,
      "location_summary": "New Haven, Connecticut • Stamford, Connecticut • Washington D.C., District of Columbia + 19 more",
      "locations": [
        {
          "city": "New Haven",
          "state": "Connecticut"
        },
        {
          "city": "Stamford",
          "state": "Connecticut"
        },
        {
          "city": "Washington D.C.",
          "state": "District of Columbia"
        },
        {
          "city": "Gainesville",
          "state": "Florida"
        },
        {
          "city": "Gulf Breeze",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04965675"
    },
    {
      "nct_id": "NCT03896256",
      "title": "Ketamine for Refractory Chronic Migraine: a Pilot Study",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "EARLY_PHASE1"
      ],
      "conditions": [
        "Migraine Headache With Intractable Migraine"
      ],
      "interventions": [
        {
          "name": "ketamine infusion",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Thomas Jefferson University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 6,
      "start_date": "2019-03-22",
      "completion_date": "2020-01-01",
      "has_results": false,
      "last_update_posted_date": "2020-03-11",
      "last_synced_at": "2026-10-06T02:43:03.375Z",
      "location_count": 1,
      "location_summary": "Philadelphia, Pennsylvania",
      "locations": [
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03896256"
    },
    {
      "nct_id": "NCT05754190",
      "title": "Assessing Symptom and Mood Dynamics in Pain Using the Smartphone Application SOMA",
      "overall_status": "RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Chronic Pain",
        "Acute Pain",
        "Post Operative Pain",
        "Fibromyalgia, Primary",
        "Fibromyalgia, Secondary",
        "Fibromyalgia",
        "Irritable Bowel Syndrome",
        "Chronic Headache Disorder",
        "Chronic Migraine",
        "Chronic Pelvic Pain Syndrome",
        "Temporomandibular Joint Disorders",
        "Endometriosis-related Pain",
        "Arthritis",
        "Chronic Low-back Pain",
        "Failed Back Surgery Syndrome",
        "Post Herpetic Neuralgia",
        "Neuropathic Pain",
        "Painful Diabetic Neuropathy",
        "Painful Bladder Syndrome",
        "Trauma-related Wound",
        "Trauma, Multiple",
        "Chronic Pain Syndrome",
        "Chronic Shoulder Pain"
      ],
      "interventions": [
        {
          "name": "SOMA pain manager smartphone application",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Brown University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 800,
      "start_date": "2023-06-20",
      "completion_date": "2026-05-30",
      "has_results": false,
      "last_update_posted_date": "2025-09-19",
      "last_synced_at": "2026-10-06T02:43:03.375Z",
      "location_count": 1,
      "location_summary": "Providence, Rhode Island",
      "locations": [
        {
          "city": "Providence",
          "state": "Rhode Island"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05754190"
    },
    {
      "nct_id": "NCT00269581",
      "title": "Headstrong Intervention for Pediatric Headache",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Chronic Headaches"
      ],
      "interventions": [
        {
          "name": "Educational CD-rom",
          "type": "OTHER"
        },
        {
          "name": "Headstrong CD-rom",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Michael Rapoff, Ph.D.",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "7 Years",
        "maximum_age": "12 Years",
        "sex": "ALL",
        "summary": "7 Years to 12 Years"
      },
      "enrollment_count": 35,
      "start_date": "2004-08",
      "completion_date": "2010-05",
      "has_results": false,
      "last_update_posted_date": "2012-09-25",
      "last_synced_at": "2026-10-06T02:43:03.375Z",
      "location_count": 2,
      "location_summary": "Kansas City, Kansas • Kansas City, Missouri",
      "locations": [
        {
          "city": "Kansas City",
          "state": "Kansas"
        },
        {
          "city": "Kansas City",
          "state": "Missouri"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00269581"
    },
    {
      "nct_id": "NCT02720211",
      "title": "Spectacle Tints and Thin-Films for Migraine",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Headache Migraine Chronic"
      ],
      "interventions": [
        {
          "name": "Gray tinted spectacle lenses",
          "type": "DEVICE"
        },
        {
          "name": "Thin-Film spectacle lenses",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "University of Utah",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "60 Years",
        "sex": "ALL",
        "summary": "18 Years to 60 Years"
      },
      "enrollment_count": 10,
      "start_date": "2016-08",
      "completion_date": "2018-11-06",
      "has_results": true,
      "last_update_posted_date": "2022-11-29",
      "last_synced_at": "2026-10-06T02:43:03.375Z",
      "location_count": 4,
      "location_summary": "Phoenix, Arizona • Boston, Massachusetts • Great Neck, New York + 1 more",
      "locations": [
        {
          "city": "Phoenix",
          "state": "Arizona"
        },
        {
          "city": "Boston",
          "state": "Massachusetts"
        },
        {
          "city": "Great Neck",
          "state": "New York"
        },
        {
          "city": "Salt Lake City",
          "state": "Utah"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02720211"
    }
  ]
}