{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Chronic+Periodontitis&page=2",
    "query": {
      "condition": "Chronic Periodontitis",
      "page": 2
    },
    "page_size": 10
  },
  "pagination": {
    "page": 2,
    "page_size": 10,
    "total_count": 10,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Chronic+Periodontitis&page=1&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-06-07T11:46:58.221Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT04978324",
      "title": "Scaling and Root Planning With Localized Delivery of Autogenous Growth Factors- Platelet Rich Fibrin (PRF)",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Periodontitis Chronic Generalized Severe",
        "Periodontitis Chronic Generalized Moderate"
      ],
      "interventions": [
        {
          "name": "leukocyte platelet rich fibrin (L-PRF)",
          "type": "BIOLOGICAL"
        },
        {
          "name": "Scaling and Root Planing",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "BIOLOGICAL",
        "PROCEDURE"
      ],
      "sponsor": "Virginia Commonwealth University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 0,
      "start_date": "2022-05",
      "completion_date": "2022-12",
      "has_results": false,
      "last_update_posted_date": "2022-05-12",
      "last_synced_at": "2026-06-07T11:46:58.221Z",
      "location_count": 1,
      "location_summary": "Richmond, Virginia",
      "locations": [
        {
          "city": "Richmond",
          "state": "Virginia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04978324"
    },
    {
      "nct_id": "NCT03262701",
      "title": "Adjunctive Hydrogen Peroxide for Periodontal Therapy",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Periodontitis, Chronic"
      ],
      "interventions": [
        {
          "name": "Hydrogen Peroxide Gel, 13 weeks",
          "type": "DRUG"
        },
        {
          "name": "Hydrogen Peroxide Gel, 26 weeks",
          "type": "DRUG"
        },
        {
          "name": "Scaling and Root planing group",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DRUG",
        "OTHER"
      ],
      "sponsor": "Loma Linda University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "18 Years to 80 Years"
      },
      "enrollment_count": 42,
      "start_date": "2018-04-02",
      "completion_date": "2021-02-08",
      "has_results": true,
      "last_update_posted_date": "2022-12-21",
      "last_synced_at": "2026-06-07T11:46:58.221Z",
      "location_count": 1,
      "location_summary": "Loma Linda, California",
      "locations": [
        {
          "city": "Loma Linda",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03262701"
    },
    {
      "nct_id": "NCT01568944",
      "title": "Role of Infected Blood Dendritic Cells in Heart Disease Risk",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Chronic Periodontitis"
      ],
      "interventions": [
        {
          "name": "Oral Antibiotic and Oral Rinse",
          "type": "DRUG"
        },
        {
          "name": "Standard Treatment",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "DRUG",
        "PROCEDURE"
      ],
      "sponsor": "Augusta University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "40 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "40 Years and older"
      },
      "enrollment_count": 18,
      "start_date": "2012-03",
      "completion_date": "2014-09",
      "has_results": true,
      "last_update_posted_date": "2020-05-12",
      "last_synced_at": "2026-06-07T11:46:58.221Z",
      "location_count": 1,
      "location_summary": "Augusta, Georgia",
      "locations": [
        {
          "city": "Augusta",
          "state": "Georgia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01568944"
    },
    {
      "nct_id": "NCT07053969",
      "title": "The Effect Of Enamel Matrix Derivatives On Gingival Tissue Thickness",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Dental Implantation",
        "Missing Teeth",
        "Periodontitis, Adult",
        "Mucositis"
      ],
      "interventions": [
        {
          "name": "Enamel Matrix Derivative",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "The University of Texas Health Science Center at San Antonio",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "18 Years",
        "sex": "ALL",
        "summary": "18 Years to 18 Years"
      },
      "enrollment_count": 32,
      "start_date": "2025-08-31",
      "completion_date": "2027-09",
      "has_results": false,
      "last_update_posted_date": "2025-11-12",
      "last_synced_at": "2026-06-07T11:46:58.221Z",
      "location_count": 1,
      "location_summary": "San Antonio, Texas",
      "locations": [
        {
          "city": "San Antonio",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07053969"
    },
    {
      "nct_id": "NCT03241511",
      "title": "Novel PAradigm to Improve Inflammatory Burden in ESRD (rePAIR): A Pilot and Feasibility Randomized Controlled Trial",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Chronic Periodontitis",
        "End Stage Renal Disease"
      ],
      "interventions": [
        {
          "name": "Test",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "UConn Health",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "21 Years and older"
      },
      "enrollment_count": 66,
      "start_date": "2017-11-07",
      "completion_date": "2020-12-01",
      "has_results": false,
      "last_update_posted_date": "2025-06-05",
      "last_synced_at": "2026-06-07T11:46:58.221Z",
      "location_count": 1,
      "location_summary": "Farmington, Connecticut",
      "locations": [
        {
          "city": "Farmington",
          "state": "Connecticut"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03241511"
    },
    {
      "nct_id": "NCT00223470",
      "title": "Cytokine Regulation of Periradicular Pain in Humans",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Chronic Apical Periodontitis of Pulpal Origin"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "The University of Texas Health Science Center at San Antonio",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "16 Years",
        "maximum_age": "60 Years",
        "sex": "ALL",
        "summary": "16 Years to 60 Years"
      },
      "enrollment_count": 9,
      "start_date": "2002-10",
      "completion_date": "2008-06",
      "has_results": false,
      "last_update_posted_date": "2012-03-09",
      "last_synced_at": "2026-06-07T11:46:58.221Z",
      "location_count": 1,
      "location_summary": "San Antonio, Texas",
      "locations": [
        {
          "city": "San Antonio",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00223470"
    },
    {
      "nct_id": "NCT03628872",
      "title": "Treatment of Periodontitis With Er:YAG Laser",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Generalized Moderate Chronic Periodontitis",
        "Generalized Severe Chronic Periodontitis",
        "Periodontal Diseases"
      ],
      "interventions": [
        {
          "name": "Scaling and root planing",
          "type": "PROCEDURE"
        },
        {
          "name": "Er:YAG Laser",
          "type": "DEVICE"
        },
        {
          "name": "Hand instruments",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "PROCEDURE",
        "DEVICE"
      ],
      "sponsor": "Columbia University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 29,
      "start_date": "2018-03-02",
      "completion_date": "2019-06-01",
      "has_results": true,
      "last_update_posted_date": "2024-12-09",
      "last_synced_at": "2026-06-07T11:46:58.221Z",
      "location_count": 1,
      "location_summary": "New York, New York",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03628872"
    },
    {
      "nct_id": "NCT00223379",
      "title": "Longitudinal Endodontic Study of Apical Preparation Size",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Chronic Apical Periodontitis of Pulpal Origin"
      ],
      "interventions": [
        {
          "name": "Endodontic procedure with varied apical preparation size",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "The University of Texas Health Science Center at San Antonio",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "70 Years",
        "sex": "ALL",
        "summary": "18 Years to 70 Years"
      },
      "enrollment_count": 36,
      "start_date": "2002-12",
      "completion_date": "2007-12",
      "has_results": false,
      "last_update_posted_date": "2012-03-08",
      "last_synced_at": "2026-06-07T11:46:58.221Z",
      "location_count": 1,
      "location_summary": "San Antonio, Texas",
      "locations": [
        {
          "city": "San Antonio",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00223379"
    },
    {
      "nct_id": "NCT03003689",
      "title": "Effects of Scaling and Root Planing With and Without Er:YAG Laser in Chronic Periodontitis Patients",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Chronic Periodontitis"
      ],
      "interventions": [
        {
          "name": "Scaling and Root Planing",
          "type": "PROCEDURE"
        },
        {
          "name": "Er:YAG Laser",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "PROCEDURE",
        "DEVICE"
      ],
      "sponsor": "Tufts University School of Dental Medicine",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 56,
      "start_date": "2017-04-20",
      "completion_date": "2018-03",
      "has_results": false,
      "last_update_posted_date": "2018-01-11",
      "last_synced_at": "2026-06-07T11:46:58.221Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03003689"
    },
    {
      "nct_id": "NCT00997178",
      "title": "Diabetes and Periodontal Therapy Trial",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Chronic Periodontitis",
        "Type 2 Diabetes"
      ],
      "interventions": [
        {
          "name": "Non-surgical periodontal therapy",
          "type": "PROCEDURE"
        },
        {
          "name": "Delayed non-surgical periodontal therapy",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "PROCEDURE",
        "OTHER"
      ],
      "sponsor": "Stony Brook University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "35 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "35 Years and older"
      },
      "enrollment_count": 514,
      "start_date": "2009-10",
      "completion_date": "2012-12",
      "has_results": false,
      "last_update_posted_date": "2014-01-20",
      "last_synced_at": "2026-06-07T11:46:58.221Z",
      "location_count": 8,
      "location_summary": "Birmingham, Alabama • Minneapolis, Minnesota • Stony Brook, New York + 2 more",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        },
        {
          "city": "Minneapolis",
          "state": "Minnesota"
        },
        {
          "city": "Minneapolis",
          "state": "Minnesota"
        },
        {
          "city": "Stony Brook",
          "state": "New York"
        },
        {
          "city": "Stony Brook",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00997178"
    }
  ]
}