{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Chronic+Total+Occlusion+of+Coronary+Artery",
    "query": {
      "condition": "Chronic Total Occlusion of Coronary Artery"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 17,
    "total_pages": 2,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Chronic+Total+Occlusion+of+Coronary+Artery&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-06-10T06:08:20.959Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT04774913",
      "title": "Invest-CTO PCI Trial",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Chronic Total Occlusion of Coronary Artery",
        "Angina Pectoris",
        "Quality of Life",
        "PROM"
      ],
      "interventions": [
        {
          "name": "Chronic total occlusion(CTO) percutaneous coronary intervention (PCI)",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Haukeland University Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 200,
      "start_date": "2021-12-08",
      "completion_date": "2026-10",
      "has_results": false,
      "last_update_posted_date": "2025-11-21",
      "last_synced_at": "2026-06-10T06:08:20.959Z",
      "location_count": 1,
      "location_summary": "New York, New York",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04774913"
    },
    {
      "nct_id": "NCT03118544",
      "title": "REduction of Contrast Via DyeVert Used in CTO Procedures",
      "overall_status": "TERMINATED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Chronic Total Occlusion of Coronary Artery"
      ],
      "interventions": [
        {
          "name": "DyeVert System",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Minneapolis Heart Institute Foundation",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 21,
      "start_date": "2017-03-26",
      "completion_date": "2018-02-02",
      "has_results": false,
      "last_update_posted_date": "2018-05-17",
      "last_synced_at": "2026-06-10T06:08:20.959Z",
      "location_count": 3,
      "location_summary": "Minneapolis, Minnesota",
      "locations": [
        {
          "city": "Minneapolis",
          "state": "Minnesota"
        },
        {
          "city": "Minneapolis",
          "state": "Minnesota"
        },
        {
          "city": "Minneapolis",
          "state": "Minnesota"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03118544"
    },
    {
      "nct_id": "NCT04059536",
      "title": "Registry Study to Evaluate the Performance and Safety of Roxwood Medical Catheters in Arteries of Participants With a Stenotic Lesion or Chronic Total Occlusion (CTO)",
      "overall_status": "WITHDRAWN",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Chronic Total Occlusion",
        "Atherosclerosis",
        "Coronary Artery Disease",
        "Peripheral Artery Disease"
      ],
      "interventions": [
        {
          "name": "Roxwood Anchoring Catheters",
          "type": "DEVICE"
        },
        {
          "name": "Acetylsalicylic Acid",
          "type": "DRUG"
        },
        {
          "name": "Heparin",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "DRUG"
      ],
      "sponsor": "Boston Scientific Corporation",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "25 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "25 Years to 80 Years"
      },
      "enrollment_count": 0,
      "start_date": "2019-10-31",
      "completion_date": "2020-03-31",
      "has_results": false,
      "last_update_posted_date": "2021-07-21",
      "last_synced_at": "2026-06-10T06:08:20.959Z",
      "location_count": 11,
      "location_summary": "Phoenix, Arizona • Gainesville, Florida • Hobart, Indiana + 8 more",
      "locations": [
        {
          "city": "Phoenix",
          "state": "Arizona"
        },
        {
          "city": "Gainesville",
          "state": "Florida"
        },
        {
          "city": "Hobart",
          "state": "Indiana"
        },
        {
          "city": "Hyattsville",
          "state": "Maryland"
        },
        {
          "city": "Detroit",
          "state": "Michigan"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04059536"
    },
    {
      "nct_id": "NCT06358508",
      "title": "Sapphire 3 CTO Study",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Coronary Artery Disease",
        "Coronary Disease",
        "Myocardial Ischemia",
        "Heart Diseases",
        "Arteriosclerosis",
        "Cardiovascular Diseases",
        "Chronic Total Occlusion",
        "Chronic Total Occlusion of Coronary Artery"
      ],
      "interventions": [
        {
          "name": "Sapphire 3 Coronary Dilatation Catheter",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "OrbusNeich",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 170,
      "start_date": "2024-11-06",
      "completion_date": "2025-10-21",
      "has_results": false,
      "last_update_posted_date": "2026-01-12",
      "last_synced_at": "2026-06-10T06:08:20.959Z",
      "location_count": 12,
      "location_summary": "Stanford, California • Torrance, California • Atlanta, Georgia + 5 more",
      "locations": [
        {
          "city": "Stanford",
          "state": "California"
        },
        {
          "city": "Torrance",
          "state": "California"
        },
        {
          "city": "Atlanta",
          "state": "Georgia"
        },
        {
          "city": "Atlanta",
          "state": "Georgia"
        },
        {
          "city": "Atlanta",
          "state": "Georgia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06358508"
    },
    {
      "nct_id": "NCT02061436",
      "title": "Prospective Global Registry for the Study of Chronic Total Occlusion Intervention",
      "overall_status": "UNKNOWN",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Coronary Artery Disease"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Minneapolis Heart Institute Foundation",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 2000,
      "start_date": "2012-01",
      "completion_date": "2024-01",
      "has_results": false,
      "last_update_posted_date": "2022-03-10",
      "last_synced_at": "2026-06-10T06:08:20.959Z",
      "location_count": 42,
      "location_summary": "Phoenix, Arizona • Little Rock, Arkansas • San Diego, California + 31 more",
      "locations": [
        {
          "city": "Phoenix",
          "state": "Arizona"
        },
        {
          "city": "Little Rock",
          "state": "Arkansas"
        },
        {
          "city": "San Diego",
          "state": "California"
        },
        {
          "city": "Torrance",
          "state": "California"
        },
        {
          "city": "Loveland",
          "state": "Colorado"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02061436"
    },
    {
      "nct_id": "NCT00378612",
      "title": "ACROSS-Cypher Total Occlusion Study of Coronary Arteries 4 Trial",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Coronary Occlusions"
      ],
      "interventions": [
        {
          "name": "Cypher sirolimus eluting coronary stent",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Sunil Rao",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 200,
      "start_date": "2005-06",
      "completion_date": "2012-09",
      "has_results": false,
      "last_update_posted_date": "2014-09-12",
      "last_synced_at": "2026-06-10T06:08:20.959Z",
      "location_count": 13,
      "location_summary": "La Jolla, California • Washington D.C., District of Columbia • Atlanta, Georgia + 8 more",
      "locations": [
        {
          "city": "La Jolla",
          "state": "California"
        },
        {
          "city": "La Jolla",
          "state": "California"
        },
        {
          "city": "Washington D.C.",
          "state": "District of Columbia"
        },
        {
          "city": "Atlanta",
          "state": "Georgia"
        },
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00378612"
    },
    {
      "nct_id": "NCT02510547",
      "title": "Comparison of a CrossBoss First Versus Standard Wire Escalation Strategy for Crossing Coronary Chronic Total Occlusion: the \"CrossBoss First\" Trial",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Arteriosclerosis",
        "Coronary Artery Disease",
        "Myocardial Ischemia",
        "Coronary Disease"
      ],
      "interventions": [
        {
          "name": "CrossBoss Catheter",
          "type": "PROCEDURE"
        },
        {
          "name": "Antegrade Wire Escalation Strategy",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "North Texas Veterans Healthcare System",
      "sponsor_class": "FED",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 246,
      "start_date": "2015-09",
      "completion_date": "2017-08",
      "has_results": false,
      "last_update_posted_date": "2018-01-25",
      "last_synced_at": "2026-06-10T06:08:20.959Z",
      "location_count": 11,
      "location_summary": "Boston, Massachusetts • Detroit, Michigan • Minneapolis, Minnesota + 8 more",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        },
        {
          "city": "Detroit",
          "state": "Michigan"
        },
        {
          "city": "Minneapolis",
          "state": "Minnesota"
        },
        {
          "city": "Saint Paul",
          "state": "Minnesota"
        },
        {
          "city": "Columbia",
          "state": "Missouri"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02510547"
    },
    {
      "nct_id": "NCT02477579",
      "title": "A Prospective, Multi-Center, Pivotal Study to Evaluate the Safety and Effectiveness of the NovaCross™ Micro-catheter in Facilitating Crossing Chronic Total Occlusion (CTO) Coronary Lesions",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Chronic Total Occlusion of Coronary Artery"
      ],
      "interventions": [
        {
          "name": "NovaCross",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Nitiloop Ltd.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "18 Years to 80 Years"
      },
      "enrollment_count": 145,
      "start_date": "2015-05-17",
      "completion_date": "2017-08-10",
      "has_results": false,
      "last_update_posted_date": "2017-08-17",
      "last_synced_at": "2026-06-10T06:08:20.959Z",
      "location_count": 4,
      "location_summary": "Little Rock, Arkansas • Naperville, Illinois • New York, New York + 1 more",
      "locations": [
        {
          "city": "Little Rock",
          "state": "Arkansas"
        },
        {
          "city": "Naperville",
          "state": "Illinois"
        },
        {
          "city": "New York",
          "state": "New York"
        },
        {
          "city": "York",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02477579"
    },
    {
      "nct_id": "NCT03988166",
      "title": "Chronic Total Occlusion Percutaneous Coronary Intervention Study",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Chronic Total Occlusion",
        "Ischemic Heart Disease",
        "Chronic Total Occlusion of Coronary Artery"
      ],
      "interventions": [
        {
          "name": "Chronic Total Occlusion Revascularization",
          "type": "PROCEDURE"
        },
        {
          "name": "GuideLiner® V3 catheter, TrapLiner® catheter, Turnpike® catheter",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "PROCEDURE",
        "DEVICE"
      ],
      "sponsor": "Vascular Solutions LLC",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 150,
      "start_date": "2020-05-20",
      "completion_date": "2021-02-22",
      "has_results": true,
      "last_update_posted_date": "2022-09-28",
      "last_synced_at": "2026-06-10T06:08:20.959Z",
      "location_count": 13,
      "location_summary": "Torrance, California • Atlanta, Georgia • Boston, Massachusetts + 6 more",
      "locations": [
        {
          "city": "Torrance",
          "state": "California"
        },
        {
          "city": "Atlanta",
          "state": "Georgia"
        },
        {
          "city": "Atlanta",
          "state": "Georgia"
        },
        {
          "city": "Boston",
          "state": "Massachusetts"
        },
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03988166"
    },
    {
      "nct_id": "NCT01186198",
      "title": "A Clinical Evaluation of the MINI TREK RX 1.20 mm Coronary Dilatation Catheter in Stenotic Lesions",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Ischemic Heart Disease",
        "Coronary Artery Stenosis",
        "Chronic Coronary Total Occlusion",
        "Coronary Bypass Graft Stenosis"
      ],
      "interventions": [
        {
          "name": "MINI TREK RX 1.20 mm Coronary Dilatation Catheter",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Abbott Medical Devices",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 71,
      "start_date": "2010-08-12",
      "completion_date": "2010-12-30",
      "has_results": true,
      "last_update_posted_date": "2023-11-13",
      "last_synced_at": "2026-06-10T06:08:20.959Z",
      "location_count": 4,
      "location_summary": "La Jolla, California • Salisbury, Maryland • Petoskey, Michigan + 1 more",
      "locations": [
        {
          "city": "La Jolla",
          "state": "California"
        },
        {
          "city": "Salisbury",
          "state": "Maryland"
        },
        {
          "city": "Petoskey",
          "state": "Michigan"
        },
        {
          "city": "Cincinnati",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01186198"
    }
  ]
}