{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Cigarette+Use&page=21",
    "query": {
      "condition": "Cigarette Use",
      "page": 21
    },
    "page_size": 10
  },
  "pagination": {
    "page": 21,
    "page_size": 10,
    "total_count": 690,
    "total_pages": 69,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Cigarette+Use&page=22&page_size=10",
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Cigarette+Use&page=20&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-10-29T03:32:45.843Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT00018161",
      "title": "Treatment to Quit Smoking",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Smoking"
      ],
      "interventions": [
        {
          "name": "Mecamylamine",
          "type": "DRUG"
        },
        {
          "name": "Nicotine Patch",
          "type": "DRUG"
        },
        {
          "name": "Cigarette brand switching",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "DRUG",
        "BEHAVIORAL"
      ],
      "sponsor": "US Department of Veterans Affairs",
      "sponsor_class": "FED",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": null,
      "start_date": "1997-01",
      "completion_date": "2001-06",
      "has_results": false,
      "last_update_posted_date": "2009-01-21",
      "last_synced_at": "2026-10-29T03:32:45.843Z",
      "location_count": 1,
      "location_summary": "Durham, North Carolina",
      "locations": [
        {
          "city": "Durham",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00018161"
    },
    {
      "nct_id": "NCT01664741",
      "title": "Nicotine Dependence, Withdrawal and Replacement Therapy Assessed by PET Imaging",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Nicotine Dependence"
      ],
      "interventions": [
        {
          "name": "Nicotine patch - transdermal",
          "type": "DRUG"
        },
        {
          "name": "placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Johns Hopkins University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "60 Years",
        "sex": "ALL",
        "summary": "21 Years to 60 Years"
      },
      "enrollment_count": 127,
      "start_date": "2012-04",
      "completion_date": "2018-12",
      "has_results": true,
      "last_update_posted_date": "2019-05-09",
      "last_synced_at": "2026-10-29T03:32:45.843Z",
      "location_count": 1,
      "location_summary": "Baltimore, Maryland",
      "locations": [
        {
          "city": "Baltimore",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01664741"
    },
    {
      "nct_id": "NCT05627596",
      "title": "Free Samples for Health",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Cigarette Smoking"
      ],
      "interventions": [
        {
          "name": "Ask-Advise-Refer",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Nicotine Patch, 14 Mg/24 Hr Transdermal Film, Extended Release",
          "type": "DRUG"
        },
        {
          "name": "Nicotine lozenge",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL",
        "DRUG"
      ],
      "sponsor": "Sandra Japuntich",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 1239,
      "start_date": "2023-06-12",
      "completion_date": "2025-06-24",
      "has_results": true,
      "last_update_posted_date": "2026-07-24",
      "last_synced_at": "2026-10-29T03:32:45.843Z",
      "location_count": 1,
      "location_summary": "Minneapolis, Minnesota",
      "locations": [
        {
          "city": "Minneapolis",
          "state": "Minnesota"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05627596"
    },
    {
      "nct_id": "NCT00656500",
      "title": "Quitline Use in Surgical Patients",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Tobacco Dependence"
      ],
      "interventions": [
        {
          "name": "Standard brief advice",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Quitline intervention",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Mayo Clinic",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 300,
      "start_date": "2007-07",
      "completion_date": "2011-06",
      "has_results": false,
      "last_update_posted_date": "2012-02-03",
      "last_synced_at": "2026-10-29T03:32:45.843Z",
      "location_count": 1,
      "location_summary": "Rochester, Minnesota",
      "locations": [
        {
          "city": "Rochester",
          "state": "Minnesota"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00656500"
    },
    {
      "nct_id": "NCT05658471",
      "title": "Pharmacokinetics and Pharmacodynamics of Nicotine With Use of Standardized Research Electronic Cigarette (SREC)",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Nicotine Dependence",
        "Tobacco Toxicity",
        "Cardiovascular Risk Factors"
      ],
      "interventions": [
        {
          "name": "Standardized Research E-Cigarette (SREC)",
          "type": "OTHER"
        },
        {
          "name": "Over the Counter E-Cigarette (EC)",
          "type": "OTHER"
        },
        {
          "name": "Biological Samples",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Smoking-related Questionnaires",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER",
        "BEHAVIORAL"
      ],
      "sponsor": "University of California, San Francisco",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "70 Years",
        "sex": "ALL",
        "summary": "21 Years to 70 Years"
      },
      "enrollment_count": 32,
      "start_date": "2023-02-01",
      "completion_date": "2026-01-31",
      "has_results": false,
      "last_update_posted_date": "2026-03-27",
      "last_synced_at": "2026-10-29T03:32:45.843Z",
      "location_count": 1,
      "location_summary": "San Francisco, California",
      "locations": [
        {
          "city": "San Francisco",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05658471"
    },
    {
      "nct_id": "NCT05118139",
      "title": "CSD201203: A Study to Determine Subject Puffing Patterns of a Non-cylindrical, Closed, Electronic Nicotine Delivery System at Three Nicotine Concentrations in an Ambulatory Setting",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Smoking",
        "Tobacco Use",
        "Electronic Cigarette Use"
      ],
      "interventions": [
        {
          "name": "P1211216",
          "type": "OTHER"
        },
        {
          "name": "P1213416",
          "type": "OTHER"
        },
        {
          "name": "P1213716",
          "type": "OTHER"
        },
        {
          "name": "P1213616",
          "type": "OTHER"
        },
        {
          "name": "P1213816",
          "type": "OTHER"
        },
        {
          "name": "P1211916",
          "type": "OTHER"
        },
        {
          "name": "P1210016",
          "type": "OTHER"
        },
        {
          "name": "P1211217",
          "type": "OTHER"
        },
        {
          "name": "P1213417",
          "type": "OTHER"
        },
        {
          "name": "P1211222",
          "type": "OTHER"
        },
        {
          "name": "P1213422",
          "type": "OTHER"
        },
        {
          "name": "P1213722",
          "type": "OTHER"
        },
        {
          "name": "P1213622",
          "type": "OTHER"
        },
        {
          "name": "P1213822",
          "type": "OTHER"
        },
        {
          "name": "P1211922",
          "type": "OTHER"
        },
        {
          "name": "P1210022",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "RAI Services Company",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "21 Years and older"
      },
      "enrollment_count": 240,
      "start_date": "2022-02-11",
      "completion_date": "2022-07-30",
      "has_results": false,
      "last_update_posted_date": "2025-04-10",
      "last_synced_at": "2026-10-29T03:32:45.843Z",
      "location_count": 4,
      "location_summary": "Stockbridge, Georgia • Lexington, Kentucky • Hickory, North Carolina + 1 more",
      "locations": [
        {
          "city": "Stockbridge",
          "state": "Georgia"
        },
        {
          "city": "Lexington",
          "state": "Kentucky"
        },
        {
          "city": "Hickory",
          "state": "North Carolina"
        },
        {
          "city": "High Point",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05118139"
    },
    {
      "nct_id": "NCT07661550",
      "title": "Prevention of Postpartum Smoking Relapse and Related Health Consequences by Breastfeeding Promotion",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Smoking ( Cigarette)",
        "Breastfeeding"
      ],
      "interventions": [
        {
          "name": "Breastfeeding promotion",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Attention placebo control",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "State University of New York at Buffalo",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "FEMALE",
        "summary": "18 Years and older · Female only"
      },
      "enrollment_count": 280,
      "start_date": "2026-01-01",
      "completion_date": "2031-07-31",
      "has_results": false,
      "last_update_posted_date": "2026-06-22",
      "last_synced_at": "2026-10-29T03:32:45.843Z",
      "location_count": 1,
      "location_summary": "Buffalo, New York",
      "locations": [
        {
          "city": "Buffalo",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07661550"
    },
    {
      "nct_id": "NCT06795997",
      "title": "Tobacco/Nicotine Purchase Patterns Across SES",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Smoking Behaviors",
        "Smoking, Non-Tobacco Products",
        "Smoking, Cigarette"
      ],
      "interventions": [
        {
          "name": "Tax Conditions",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Control Condition",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Virginia Polytechnic Institute and State University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 663,
      "start_date": "2024-12-16",
      "completion_date": "2025-03-25",
      "has_results": false,
      "last_update_posted_date": "2025-05-21",
      "last_synced_at": "2026-10-29T03:32:45.843Z",
      "location_count": 1,
      "location_summary": "Roanoke, Virginia",
      "locations": [
        {
          "city": "Roanoke",
          "state": "Virginia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06795997"
    },
    {
      "nct_id": "NCT00756704",
      "title": "The Effectiveness of Smoking Cessation Guidelines in the Emergency Department",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Cigarette Smoking"
      ],
      "interventions": [
        {
          "name": "Smoking cessation guideline implementation",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of Iowa",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 789,
      "start_date": "2008-09",
      "completion_date": "2011-06",
      "has_results": false,
      "last_update_posted_date": "2011-11-04",
      "last_synced_at": "2026-10-29T03:32:45.843Z",
      "location_count": 2,
      "location_summary": "Des Moines, Iowa • Iowa City, Iowa",
      "locations": [
        {
          "city": "Des Moines",
          "state": "Iowa"
        },
        {
          "city": "Iowa City",
          "state": "Iowa"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00756704"
    },
    {
      "nct_id": "NCT04238832",
      "title": "Salt-Based E-cigarette",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Smoking",
        "Tobacco Use"
      ],
      "interventions": [
        {
          "name": "Salt Base Nicotine",
          "type": "OTHER"
        },
        {
          "name": "Free Base Nicotine",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Medical University of South Carolina",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "21 Years and older"
      },
      "enrollment_count": 24,
      "start_date": "2020-06-16",
      "completion_date": "2021-07-23",
      "has_results": false,
      "last_update_posted_date": "2021-08-09",
      "last_synced_at": "2026-10-29T03:32:45.843Z",
      "location_count": 1,
      "location_summary": "Charleston, South Carolina",
      "locations": [
        {
          "city": "Charleston",
          "state": "South Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04238832"
    }
  ]
}