{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Circadian+Disruption",
    "query": {
      "condition": "Circadian Disruption"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 19,
    "total_pages": 2,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Circadian+Disruption&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-06-07T19:02:57.605Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT04955431",
      "title": "Circadian Rhythm Disruption Effects on Smoke Inhalation",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Inflammation",
        "Sleep Deprivation",
        "Circadian Rhythm Sleep Disorder, Shift Work Type",
        "Smoke Inhalation"
      ],
      "interventions": [
        {
          "name": "Sleep Restriction",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Normal Sleep",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of Montana",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "44 Years",
        "sex": "MALE",
        "summary": "18 Years to 44 Years · Male only"
      },
      "enrollment_count": 10,
      "start_date": "2022-01-24",
      "completion_date": "2022-04-17",
      "has_results": true,
      "last_update_posted_date": "2025-05-30",
      "last_synced_at": "2026-06-07T19:02:57.605Z",
      "location_count": 1,
      "location_summary": "Missoula, Montana",
      "locations": [
        {
          "city": "Missoula",
          "state": "Montana"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04955431"
    },
    {
      "nct_id": "NCT06505447",
      "title": "PICU-related Sleep and Circadian Dysregulation Pilot Study",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Circadian Dysrhythmia",
        "Sleep Disturbance",
        "Critical Illness",
        "Children, Only"
      ],
      "interventions": [
        {
          "name": "Daytime light exposure",
          "type": "OTHER"
        },
        {
          "name": "Daytime restricted feeding",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "State University of New York at Buffalo",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "3 Years",
        "maximum_age": "6 Years",
        "sex": "ALL",
        "summary": "3 Years to 6 Years"
      },
      "enrollment_count": 30,
      "start_date": "2024-12-06",
      "completion_date": "2027-01-01",
      "has_results": false,
      "last_update_posted_date": "2026-03-23",
      "last_synced_at": "2026-06-07T19:02:57.605Z",
      "location_count": 1,
      "location_summary": "Buffalo, New York",
      "locations": [
        {
          "city": "Buffalo",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06505447"
    },
    {
      "nct_id": "NCT07095270",
      "title": "Evaluation of Circadian OS Technology on Melatonin Suppression",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Circadian Disruption"
      ],
      "interventions": [
        {
          "name": "Circadian OS software",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Icahn School of Medicine at Mount Sinai",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "30 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "30 Years to 75 Years"
      },
      "enrollment_count": 10,
      "start_date": "2025-07-07",
      "completion_date": "2025-12-31",
      "has_results": false,
      "last_update_posted_date": "2026-01-15",
      "last_synced_at": "2026-06-07T19:02:57.605Z",
      "location_count": 1,
      "location_summary": "New York, New York",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07095270"
    },
    {
      "nct_id": "NCT01264913",
      "title": "Cardiometabolic Risk of Shiftwork",
      "overall_status": "TERMINATED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Sleep Deprivation",
        "Circadian Dysregulation",
        "Shift-Work Sleep Disorder"
      ],
      "interventions": [
        {
          "name": "sleep extension & circadian alignment",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of Chicago",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "50 Years",
        "sex": "ALL",
        "summary": "18 Years to 50 Years"
      },
      "enrollment_count": 64,
      "start_date": "2009-08",
      "completion_date": "2015-03",
      "has_results": false,
      "last_update_posted_date": "2016-10-03",
      "last_synced_at": "2026-06-07T19:02:57.605Z",
      "location_count": 1,
      "location_summary": "Chicago, Illinois",
      "locations": [
        {
          "city": "Chicago",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01264913"
    },
    {
      "nct_id": "NCT04157244",
      "title": "The Music, Sleep and Dementia Study",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Dementia",
        "Alzheimer Disease",
        "Circadian Rhythm Disorders",
        "Circadian Rhythm Sleep Disorder",
        "Insomnia",
        "Hypersomnia",
        "Cognitive Impairment",
        "Cognitive Decline",
        "Mild Cognitive Impairment",
        "Frontotemporal Dementia",
        "Neurocognitive Disorders",
        "Vascular Dementia",
        "Sleep Disorder",
        "Memory Impairment"
      ],
      "interventions": [
        {
          "name": "Tailored music listening intervention",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of Pennsylvania",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "110 Years",
        "sex": "ALL",
        "summary": "18 Years to 110 Years"
      },
      "enrollment_count": 32,
      "start_date": "2019-03-12",
      "completion_date": "2021-01-12",
      "has_results": false,
      "last_update_posted_date": "2021-01-13",
      "last_synced_at": "2026-06-07T19:02:57.605Z",
      "location_count": 1,
      "location_summary": "Philadelphia, Pennsylvania",
      "locations": [
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04157244"
    },
    {
      "nct_id": "NCT02838082",
      "title": "Optimized Sleep After Brain Injury: Sleep Hygiene Intervention After Traumatic Brain Injury",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Traumatic Brain Injury"
      ],
      "interventions": [
        {
          "name": "Sleep Hygiene Protocol",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Standard of Care",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Craig Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "55 Years",
        "sex": "MALE",
        "summary": "18 Years to 55 Years · Male only"
      },
      "enrollment_count": 22,
      "start_date": "2015-08",
      "completion_date": "2017-10",
      "has_results": false,
      "last_update_posted_date": "2018-08-02",
      "last_synced_at": "2026-06-07T19:02:57.605Z",
      "location_count": 1,
      "location_summary": "Englewood, Colorado",
      "locations": [
        {
          "city": "Englewood",
          "state": "Colorado"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02838082"
    },
    {
      "nct_id": "NCT04737200",
      "title": "The Impact of Overnight Nutrition Support on Sleep and Circadian Rhythm Disruption in the ICU",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Feeding Patterns",
        "Sleep",
        "Glucose Intolerance"
      ],
      "interventions": [
        {
          "name": "Time-of-day of enteral nutrition provision (daytime first)",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Time-of-day of enteral nutrition provision (nighttime first)",
          "type": "DIETARY_SUPPLEMENT"
        }
      ],
      "intervention_types": [
        "DIETARY_SUPPLEMENT"
      ],
      "sponsor": "Massachusetts General Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 30,
      "start_date": "2022-02-08",
      "completion_date": "2027-03-31",
      "has_results": false,
      "last_update_posted_date": "2026-05-19",
      "last_synced_at": "2026-06-07T19:02:57.605Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04737200"
    },
    {
      "nct_id": "NCT05828680",
      "title": "Circadian Rhythm Disruption in the Hospital Intensive Care Environment",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Surgery",
        "Cardiovascular Diseases"
      ],
      "interventions": [
        {
          "name": "Observation",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of Pennsylvania",
      "sponsor_class": "OTHER",
      "healthy_volunteers": null,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 15,
      "start_date": "2023-03-15",
      "completion_date": "2028-12",
      "has_results": false,
      "last_update_posted_date": "2026-01-23",
      "last_synced_at": "2026-06-07T19:02:57.605Z",
      "location_count": 1,
      "location_summary": "Philadelphia, Pennsylvania",
      "locations": [
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05828680"
    },
    {
      "nct_id": "NCT00456222",
      "title": "Impact of Sleep Disruption on the Menstrual Cycle",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Sleep",
        "Circadian Rhythm",
        "Menstrual Cycle"
      ],
      "interventions": [
        {
          "name": "Disrupting or changing the timing or the duration of sleep",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Brigham and Women's Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "30 Years",
        "sex": "FEMALE",
        "summary": "18 Years to 30 Years · Female only"
      },
      "enrollment_count": 18,
      "start_date": "2003-06",
      "completion_date": "2009-08",
      "has_results": false,
      "last_update_posted_date": "2009-08-21",
      "last_synced_at": "2026-06-07T19:02:57.605Z",
      "location_count": 2,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        },
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00456222"
    },
    {
      "nct_id": "NCT02171273",
      "title": "Impact of Chronic Circadian Disruption vs. Chronic Sleep Restriction on Metabolism",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Aging",
        "Sleep Restriction",
        "Circadian Disruption"
      ],
      "interventions": [
        {
          "name": "Circadian Disruption",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Sleep Restriction",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Control",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Brigham and Women's Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "70 Years",
        "sex": "ALL",
        "summary": "21 Years to 70 Years"
      },
      "enrollment_count": 21,
      "start_date": "2014-03-31",
      "completion_date": "2019-04-01",
      "has_results": false,
      "last_update_posted_date": "2019-08-20",
      "last_synced_at": "2026-06-07T19:02:57.605Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02171273"
    }
  ]
}