{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Circadian+Dysregulation",
    "query": {
      "condition": "Circadian Dysregulation"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 60,
    "total_pages": 6,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Circadian+Dysregulation&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-05-22T09:45:12.462Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT04953754",
      "title": "Melatonin and Vaccine Response, Immunity, and Chronobiology Study",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Vaccine Response",
        "Sleep",
        "Circadian Rhythm Disorders"
      ],
      "interventions": [
        {
          "name": "Melatonin",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Phillips Actiwatch Spectrum Plus",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DIETARY_SUPPLEMENT",
        "DEVICE"
      ],
      "sponsor": "Walter Reed National Military Medical Center",
      "sponsor_class": "FED",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "64 Years",
        "sex": "ALL",
        "summary": "18 Years to 64 Years"
      },
      "enrollment_count": 200,
      "start_date": "2022-10-25",
      "completion_date": "2025-06",
      "has_results": false,
      "last_update_posted_date": "2023-10-10",
      "last_synced_at": "2026-05-22T09:45:12.462Z",
      "location_count": 1,
      "location_summary": "Bethesda, Maryland",
      "locations": [
        {
          "city": "Bethesda",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04953754"
    },
    {
      "nct_id": "NCT01327040",
      "title": "Light Sensitization Study",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Chronobiology Disorders",
        "Circadian Rhythm Disorders",
        "Sleep Disorders, Circadian Rhythm"
      ],
      "interventions": [
        {
          "name": "light exposure",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Brigham and Women's Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "30 Years",
        "sex": "ALL",
        "summary": "21 Years to 30 Years"
      },
      "enrollment_count": 32,
      "start_date": "2010-10",
      "completion_date": "2020-12",
      "has_results": false,
      "last_update_posted_date": "2021-07-01",
      "last_synced_at": "2026-05-22T09:45:12.462Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01327040"
    },
    {
      "nct_id": "NCT04992611",
      "title": "Sleep Timing, Eating and Activity Measurement Study",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Sleep",
        "Circadian Rhythm Disorders",
        "Dietary Habits"
      ],
      "interventions": [
        {
          "name": "Sleep Extension (Early)",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Sleep Extension (Late)",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Children's Hospital Medical Center, Cincinnati",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "14 Years",
        "maximum_age": "18 Years",
        "sex": "ALL",
        "summary": "14 Years to 18 Years"
      },
      "enrollment_count": 190,
      "start_date": "2021-07-16",
      "completion_date": "2025-07-26",
      "has_results": false,
      "last_update_posted_date": "2025-12-18",
      "last_synced_at": "2026-05-22T09:45:12.462Z",
      "location_count": 1,
      "location_summary": "Cincinnati, Ohio",
      "locations": [
        {
          "city": "Cincinnati",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04992611"
    },
    {
      "nct_id": "NCT04021355",
      "title": "Timing of Sodium Intake and Nocturnal Sodium Excretion and Blood Pressure in Obese African Americans",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Obesity",
        "Hypertension",
        "Circadian Dysregulation",
        "Salt; Excess"
      ],
      "interventions": [
        {
          "name": "Oral sodium supplementation",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of Alabama at Birmingham",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "25 Years",
        "maximum_age": "45 Years",
        "sex": "ALL",
        "summary": "25 Years to 45 Years"
      },
      "enrollment_count": 53,
      "start_date": "2020-07-14",
      "completion_date": "2025-07-31",
      "has_results": false,
      "last_update_posted_date": "2025-12-17",
      "last_synced_at": "2026-05-22T09:45:12.462Z",
      "location_count": 1,
      "location_summary": "Birmingham, Alabama",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04021355"
    },
    {
      "nct_id": "NCT07438912",
      "title": "Mind After Midnight",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Suicidal Ideation",
        "Circadian Rhythm Disorders",
        "Sleep Deprivation",
        "Sleep Wake Disorders"
      ],
      "interventions": [
        {
          "name": "Sleep Pressure Manipulation",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of Arizona",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "55 Years",
        "sex": "ALL",
        "summary": "18 Years to 55 Years"
      },
      "enrollment_count": 90,
      "start_date": "2026-03-01",
      "completion_date": "2029-08-31",
      "has_results": false,
      "last_update_posted_date": "2026-02-27",
      "last_synced_at": "2026-05-22T09:45:12.462Z",
      "location_count": 1,
      "location_summary": "Tucson, Arizona",
      "locations": [
        {
          "city": "Tucson",
          "state": "Arizona"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07438912"
    },
    {
      "nct_id": "NCT00907595",
      "title": "Treating Sleep/Wake Cycle Disturbances in Basal Ganglia Disorders With Ramelteon",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Huntington's Disease",
        "Parkinson's Disease",
        "Dementia With Lewy Bodies",
        "Sleep Disorders",
        "Circadian Dysregulation"
      ],
      "interventions": [
        {
          "name": "Ramelteon",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Massachusetts General Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "20 Years",
        "maximum_age": "90 Years",
        "sex": "ALL",
        "summary": "20 Years to 90 Years"
      },
      "enrollment_count": 0,
      "start_date": "2009-05",
      "completion_date": "2010-07",
      "has_results": false,
      "last_update_posted_date": "2012-11-06",
      "last_synced_at": "2026-05-22T09:45:12.462Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00907595"
    },
    {
      "nct_id": "NCT03468400",
      "title": "Evaluation of the Reliability and Validity of a Diagnostic Sleep Disorders Questionnaire",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Sleep Apnea Syndromes",
        "Insomnia",
        "Insufficient Sleep Syndrome",
        "Circadian Rhythm Disorders"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Dayzz Live Well Ltd.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "21 Years to 65 Years"
      },
      "enrollment_count": 250,
      "start_date": "2018-03-01",
      "completion_date": "2019-09-30",
      "has_results": false,
      "last_update_posted_date": "2020-07-22",
      "last_synced_at": "2026-05-22T09:45:12.462Z",
      "location_count": 1,
      "location_summary": "Baltimore, Maryland",
      "locations": [
        {
          "city": "Baltimore",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03468400"
    },
    {
      "nct_id": "NCT03636360",
      "title": "The Impact of Artificial Sunlight on Human Sleep and Circadian Rhythms",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Sleep",
        "Circadian Dysregulation",
        "Mood"
      ],
      "interventions": [
        {
          "name": "Light",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "VA Palo Alto Health Care System",
      "sponsor_class": "FED",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "35 Years",
        "sex": "ALL",
        "summary": "18 Years to 35 Years"
      },
      "enrollment_count": 10,
      "start_date": "2019-07-01",
      "completion_date": "2021-03-01",
      "has_results": false,
      "last_update_posted_date": "2021-03-30",
      "last_synced_at": "2026-05-22T09:45:12.462Z",
      "location_count": 1,
      "location_summary": "Palo Alto, California",
      "locations": [
        {
          "city": "Palo Alto",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03636360"
    },
    {
      "nct_id": "NCT04154631",
      "title": "Implementing and Sustaining a Sleep Treatment to Improve Community Mental Part 1: Implementation Health Outcomes",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Sleep Disorder",
        "Circadian Dysregulation"
      ],
      "interventions": [
        {
          "name": "Standard Transdiagnostic Intervention for Sleep and Circadian Dysfunction (TranS-C)",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Adapted Transdiagnostic Intervention for Sleep and Circadian Dysfunction (TranS-C)",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Usual Care Delayed Treatment",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL",
        "OTHER"
      ],
      "sponsor": "University of California, Berkeley",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 489,
      "start_date": "2020-01-08",
      "completion_date": "2023-12-19",
      "has_results": true,
      "last_update_posted_date": "2025-10-27",
      "last_synced_at": "2026-05-22T09:45:12.462Z",
      "location_count": 10,
      "location_summary": "Concord, California • Fairfield, California • Goleta, California + 7 more",
      "locations": [
        {
          "city": "Concord",
          "state": "California"
        },
        {
          "city": "Fairfield",
          "state": "California"
        },
        {
          "city": "Goleta",
          "state": "California"
        },
        {
          "city": "Hanford",
          "state": "California"
        },
        {
          "city": "Lucerne",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04154631"
    },
    {
      "nct_id": "NCT03198754",
      "title": "Programmed Environmental Illumination (PEI) of Hospital Rooms to Prevent/Reduce Cancer-Related Fatigue",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Cancer-related Problem/Condition",
        "Depression",
        "Circadian Rhythm Disorders"
      ],
      "interventions": [
        {
          "name": "PEI Experimental Light",
          "type": "DEVICE"
        },
        {
          "name": "Comparison Light",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Icahn School of Medicine at Mount Sinai",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "21 Years and older"
      },
      "enrollment_count": 73,
      "start_date": "2016-07-22",
      "completion_date": "2019-01-23",
      "has_results": true,
      "last_update_posted_date": "2020-08-11",
      "last_synced_at": "2026-05-22T09:45:12.462Z",
      "location_count": 1,
      "location_summary": "New York, New York",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03198754"
    }
  ]
}