{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Circadian+Rhythm+Sleep+Disorders&page=4",
    "query": {
      "condition": "Circadian Rhythm Sleep Disorders",
      "page": 4
    },
    "page_size": 10
  },
  "pagination": {
    "page": 4,
    "page_size": 10,
    "total_count": 155,
    "total_pages": 16,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Circadian+Rhythm+Sleep+Disorders&page=5&page_size=10",
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Circadian+Rhythm+Sleep+Disorders&page=3&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-10-08T00:03:09.713Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT05551325",
      "title": "Reestablishing Sleep and Circadian Alignment in Medical Intensive Care Unit (MICU) Patients Via a Mechanistic RCT of an Sleep Chronobundle",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Critical Illness",
        "Sleep Deprivation",
        "Circadian Rhythm Sleep Disorder, Unspecified"
      ],
      "interventions": [
        {
          "name": "Chronobundle - light",
          "type": "OTHER"
        },
        {
          "name": "chronobundle - feeding",
          "type": "OTHER"
        },
        {
          "name": "chronobundle - mobility",
          "type": "OTHER"
        },
        {
          "name": "chronobundle - sleep",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Yale University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 160,
      "start_date": "2024-05-13",
      "completion_date": "2029-06-29",
      "has_results": false,
      "last_update_posted_date": "2026-05-20",
      "last_synced_at": "2026-10-08T00:03:09.713Z",
      "location_count": 2,
      "location_summary": "New Haven, Connecticut",
      "locations": [
        {
          "city": "New Haven",
          "state": "Connecticut"
        },
        {
          "city": "New Haven",
          "state": "Connecticut"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05551325"
    },
    {
      "nct_id": "NCT04792697",
      "title": "Experimental Manipulation of Sleep and Circadian Rhythms and the Role Played on Reward Function in Teens",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Delayed Sleep Phase Syndrome"
      ],
      "interventions": [
        {
          "name": "Increase morning bright light",
          "type": "OTHER"
        },
        {
          "name": "Decrease evening blue light",
          "type": "OTHER"
        },
        {
          "name": "Sleep Scheduling",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Monitor sleep, mood, and substance use",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "OTHER",
        "BEHAVIORAL"
      ],
      "sponsor": "University of Pittsburgh",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "13 Years",
        "maximum_age": "15 Years",
        "sex": "ALL",
        "summary": "13 Years to 15 Years"
      },
      "enrollment_count": 115,
      "start_date": "2021-05-01",
      "completion_date": "2026-05-31",
      "has_results": false,
      "last_update_posted_date": "2026-07-08",
      "last_synced_at": "2026-10-08T00:03:09.713Z",
      "location_count": 1,
      "location_summary": "Pittsburgh, Pennsylvania",
      "locations": [
        {
          "city": "Pittsburgh",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04792697"
    },
    {
      "nct_id": "NCT05952284",
      "title": "Couples Health Aging, Rhythms and Sleep Study",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Aging",
        "Memory Loss"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "University of Utah",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "50 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "50 Years and older"
      },
      "enrollment_count": 340,
      "start_date": "2023-09-14",
      "completion_date": "2027-07-21",
      "has_results": false,
      "last_update_posted_date": "2026-02-13",
      "last_synced_at": "2026-10-08T00:03:09.713Z",
      "location_count": 1,
      "location_summary": "Salt Lake City, Utah",
      "locations": [
        {
          "city": "Salt Lake City",
          "state": "Utah"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05952284"
    },
    {
      "nct_id": "NCT00688142",
      "title": "Sleepiness and Brain Function: The Effect of Armodafinil in Shift Work Sleep Disorder",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Shift Work Sleep Disorder"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Henry Ford Health System",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "55 Years",
        "sex": "ALL",
        "summary": "18 Years to 55 Years"
      },
      "enrollment_count": 24,
      "start_date": "2008-02",
      "completion_date": "2010-03",
      "has_results": false,
      "last_update_posted_date": "2010-03-31",
      "last_synced_at": "2026-10-08T00:03:09.713Z",
      "location_count": 1,
      "location_summary": "Detroit, Michigan",
      "locations": [
        {
          "city": "Detroit",
          "state": "Michigan"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00688142"
    },
    {
      "nct_id": "NCT03998358",
      "title": "Characterization of Fatigue in Military Personnel With Traumatic Brain Injuries",
      "overall_status": "WITHDRAWN",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Traumatic Brain Injury",
        "Neurobehavioral Manifestation",
        "Sleep Disorder",
        "Fatigue"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "National Institute of Nursing Research (NINR)",
      "sponsor_class": "NIH",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "25 Years",
        "maximum_age": "40 Years",
        "sex": "ALL",
        "summary": "25 Years to 40 Years"
      },
      "enrollment_count": 0,
      "start_date": "2021-03-19",
      "completion_date": "2021-03-19",
      "has_results": false,
      "last_update_posted_date": "2021-03-25",
      "last_synced_at": "2026-10-08T00:03:09.713Z",
      "location_count": 1,
      "location_summary": "Bethesda, Maryland",
      "locations": [
        {
          "city": "Bethesda",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03998358"
    },
    {
      "nct_id": "NCT06809335",
      "title": "A Pilot of a Personalized Circadian mHealth to Improve Sleep in Night Shift Workers",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Shift Work Sleep Disorder"
      ],
      "interventions": [
        {
          "name": "Personalized circadian mHealth",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Henry Ford Health System",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 300,
      "start_date": "2023-10-23",
      "completion_date": "2027-06",
      "has_results": false,
      "last_update_posted_date": "2026-03-02",
      "last_synced_at": "2026-10-08T00:03:09.713Z",
      "location_count": 1,
      "location_summary": "Novi, Michigan",
      "locations": [
        {
          "city": "Novi",
          "state": "Michigan"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06809335"
    },
    {
      "nct_id": "NCT04955431",
      "title": "Circadian Rhythm Disruption Effects on Smoke Inhalation",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Inflammation",
        "Sleep Deprivation",
        "Circadian Rhythm Sleep Disorder, Shift Work Type",
        "Smoke Inhalation"
      ],
      "interventions": [
        {
          "name": "Sleep Restriction",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Normal Sleep",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of Montana",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "44 Years",
        "sex": "MALE",
        "summary": "18 Years to 44 Years · Male only"
      },
      "enrollment_count": 10,
      "start_date": "2022-01-24",
      "completion_date": "2022-04-17",
      "has_results": true,
      "last_update_posted_date": "2025-05-30",
      "last_synced_at": "2026-10-08T00:03:09.713Z",
      "location_count": 1,
      "location_summary": "Missoula, Montana",
      "locations": [
        {
          "city": "Missoula",
          "state": "Montana"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04955431"
    },
    {
      "nct_id": "NCT02502045",
      "title": "Effect of Therapeutic Light on Sleep, Circadian Rhythm, and Global Function in Women With Alzheimer's",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Alzheimer's Disease"
      ],
      "interventions": [
        {
          "name": "Morning Simulated Sunlight",
          "type": "DEVICE"
        },
        {
          "name": "Non-therapeutic Red Light",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Yale University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "65 Years",
        "maximum_age": null,
        "sex": "FEMALE",
        "summary": "65 Years and older · Female only"
      },
      "enrollment_count": 18,
      "start_date": "2012-05",
      "completion_date": "2016-01",
      "has_results": false,
      "last_update_posted_date": "2017-02-20",
      "last_synced_at": "2026-10-08T00:03:09.713Z",
      "location_count": 1,
      "location_summary": "Farmington Hills, Michigan",
      "locations": [
        {
          "city": "Farmington Hills",
          "state": "Michigan"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02502045"
    },
    {
      "nct_id": "NCT01284140",
      "title": "Improving the Sleep and Circadian Rhythms of Mechanically Ventilated Patients",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Critical Illness",
        "Sleep Deprivation",
        "Respiratory Failure",
        "Sleep Disorders, Circadian Rhythm"
      ],
      "interventions": [
        {
          "name": "Sleep and circadian rhythm promotion",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Usual care",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Brian Gehlbach",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 24,
      "start_date": "2011-01",
      "completion_date": "2016-12",
      "has_results": true,
      "last_update_posted_date": "2018-05-07",
      "last_synced_at": "2026-10-08T00:03:09.713Z",
      "location_count": 2,
      "location_summary": "Chicago, Illinois • Iowa City, Iowa",
      "locations": [
        {
          "city": "Chicago",
          "state": "Illinois"
        },
        {
          "city": "Iowa City",
          "state": "Iowa"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01284140"
    },
    {
      "nct_id": "NCT06832007",
      "title": "The Effect of Light Intervention on Recovery in Individuals With Opioid Use Disorder (OUD)",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Opioid Use Disorder",
        "Sleep",
        "Circadian Rhythms",
        "fMRI Research"
      ],
      "interventions": [
        {
          "name": "AYO light glasses (experimental)",
          "type": "DEVICE"
        },
        {
          "name": "AYO light glasses (comparator)",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "University of Alabama at Birmingham",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "60 Years",
        "sex": "ALL",
        "summary": "18 Years to 60 Years"
      },
      "enrollment_count": 105,
      "start_date": "2025-09-06",
      "completion_date": "2028-09-16",
      "has_results": false,
      "last_update_posted_date": "2025-10-20",
      "last_synced_at": "2026-10-08T00:03:09.713Z",
      "location_count": 1,
      "location_summary": "Birmingham, Alabama",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06832007"
    }
  ]
}