{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Cleft+Lip+Palate",
    "query": {
      "condition": "Cleft Lip Palate"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 26,
    "total_pages": 3,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Cleft+Lip+Palate&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-06-10T22:21:10.510Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT00483223",
      "title": "Platinum for Triple-Negative Metastatic Breast Cancer and Evaluation of p63/p73 as a Biomarker of Response",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Breast Cancer"
      ],
      "interventions": [
        {
          "name": "Cisplatin",
          "type": "DRUG"
        },
        {
          "name": "carboplatin",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Massachusetts General Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 86,
      "start_date": "2007-06",
      "completion_date": "2017-06",
      "has_results": true,
      "last_update_posted_date": "2017-08-25",
      "last_synced_at": "2026-06-10T22:21:10.510Z",
      "location_count": 10,
      "location_summary": "Birmingham, Alabama • San Francisco, California • Washington D.C., District of Columbia + 5 more",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        },
        {
          "city": "San Francisco",
          "state": "California"
        },
        {
          "city": "Washington D.C.",
          "state": "District of Columbia"
        },
        {
          "city": "Baltimore",
          "state": "Maryland"
        },
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00483223"
    },
    {
      "nct_id": "NCT02702869",
      "title": "Allied Cleft & Craniofacial Quality-Improvement and Research Network (ACCQUIREnet)",
      "overall_status": "ENROLLING_BY_INVITATION",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Cleft Lip",
        "Cleft Palate",
        "Cleft Lip and Palate"
      ],
      "interventions": [
        {
          "name": "cleft lip repair",
          "type": "PROCEDURE"
        },
        {
          "name": "cleft palate repair",
          "type": "PROCEDURE"
        },
        {
          "name": "oronasal fistula repair",
          "type": "PROCEDURE"
        },
        {
          "name": "pharyngoplasty",
          "type": "PROCEDURE"
        },
        {
          "name": "gingivoperiosteoplasty",
          "type": "PROCEDURE"
        },
        {
          "name": "LeFort-1 maxillary repositioning",
          "type": "PROCEDURE"
        },
        {
          "name": "rhinoplasty",
          "type": "PROCEDURE"
        },
        {
          "name": "myringotomy and tympanostomy tube placement",
          "type": "PROCEDURE"
        },
        {
          "name": "speech therapy",
          "type": "OTHER"
        },
        {
          "name": "orthodontia",
          "type": "PROCEDURE"
        },
        {
          "name": "presurgical orthopedics",
          "type": "PROCEDURE"
        },
        {
          "name": "sound amplification for hearing",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "PROCEDURE",
        "OTHER",
        "DEVICE"
      ],
      "sponsor": "Duke University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "1 Day",
        "maximum_age": "22 Years",
        "sex": "ALL",
        "summary": "1 Day to 22 Years"
      },
      "enrollment_count": 1000,
      "start_date": "2016-10",
      "completion_date": "2031-12",
      "has_results": false,
      "last_update_posted_date": "2026-01-07",
      "last_synced_at": "2026-06-10T22:21:10.510Z",
      "location_count": 10,
      "location_summary": "Gainesville, Florida • Hollywood, Florida • Orlando, Florida + 7 more",
      "locations": [
        {
          "city": "Gainesville",
          "state": "Florida"
        },
        {
          "city": "Hollywood",
          "state": "Florida"
        },
        {
          "city": "Orlando",
          "state": "Florida"
        },
        {
          "city": "St. Petersburg",
          "state": "Florida"
        },
        {
          "city": "Portland",
          "state": "Maine"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02702869"
    },
    {
      "nct_id": "NCT00397917",
      "title": "Oral Cleft Prevention Program",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Cleft Lip",
        "Cleft Palate"
      ],
      "interventions": [
        {
          "name": "Folic acid: 4 mg versus 0.4 mg per day",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of Iowa",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "16 Years",
        "maximum_age": "45 Years",
        "sex": "FEMALE",
        "summary": "16 Years to 45 Years · Female only"
      },
      "enrollment_count": 4000,
      "start_date": "2006-11",
      "completion_date": "2013-07",
      "has_results": false,
      "last_update_posted_date": "2017-03-31",
      "last_synced_at": "2026-06-10T22:21:10.510Z",
      "location_count": 1,
      "location_summary": "Iowa City, Iowa",
      "locations": [
        {
          "city": "Iowa City",
          "state": "Iowa"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00397917"
    },
    {
      "nct_id": "NCT01046591",
      "title": "Sleep and Behavior in Children With Cleft Palate",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Cleft Palate"
      ],
      "interventions": [
        {
          "name": "Polysomnography",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "University of Michigan",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "6 Years",
        "maximum_age": "15 Years",
        "sex": "ALL",
        "summary": "6 Years to 15 Years"
      },
      "enrollment_count": 82,
      "start_date": "2006-12",
      "completion_date": "2011-12",
      "has_results": false,
      "last_update_posted_date": "2012-03-07",
      "last_synced_at": "2026-06-10T22:21:10.510Z",
      "location_count": 1,
      "location_summary": "Ann Arbor, Michigan",
      "locations": [
        {
          "city": "Ann Arbor",
          "state": "Michigan"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01046591"
    },
    {
      "nct_id": "NCT00070811",
      "title": "Assessing the Results of Lip Surgery in Patients With Cleft Lip and Palate",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Cleft Lip",
        "Cleft Lip and Palate"
      ],
      "interventions": [
        {
          "name": "Lip revision surgery",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "University of North Carolina, Chapel Hill",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "3 Months",
        "maximum_age": "21 Years",
        "sex": "ALL",
        "summary": "3 Months to 21 Years"
      },
      "enrollment_count": 127,
      "start_date": "2001-08",
      "completion_date": "2012-12",
      "has_results": false,
      "last_update_posted_date": "2013-07-04",
      "last_synced_at": "2026-06-10T22:21:10.510Z",
      "location_count": 1,
      "location_summary": "Chapel Hill, North Carolina",
      "locations": [
        {
          "city": "Chapel Hill",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00070811"
    },
    {
      "nct_id": "NCT06801535",
      "title": "Efficacy of 3D-Printed Mouth Splints",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Microstomia"
      ],
      "interventions": [
        {
          "name": "Splint",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Wake Forest University Health Sciences",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "2 Years",
        "maximum_age": "99 Years",
        "sex": "ALL",
        "summary": "2 Years to 99 Years"
      },
      "enrollment_count": 10,
      "start_date": "2025-02-21",
      "completion_date": "2026-12",
      "has_results": false,
      "last_update_posted_date": "2025-12-17",
      "last_synced_at": "2026-06-10T22:21:10.510Z",
      "location_count": 1,
      "location_summary": "Winston-Salem, North Carolina",
      "locations": [
        {
          "city": "Winston-Salem",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06801535"
    },
    {
      "nct_id": "NCT04771156",
      "title": "Ketorolac in Palatoplasty",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Cleft Lip and Palate"
      ],
      "interventions": [
        {
          "name": "Ketorolac",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "The University of Texas Health Science Center, Houston",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "6 Months",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "6 Months and older"
      },
      "enrollment_count": 74,
      "start_date": "2021-09-17",
      "completion_date": "2027-04-01",
      "has_results": false,
      "last_update_posted_date": "2026-02-19",
      "last_synced_at": "2026-06-10T22:21:10.510Z",
      "location_count": 1,
      "location_summary": "Houston, Texas",
      "locations": [
        {
          "city": "Houston",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04771156"
    },
    {
      "nct_id": "NCT03537976",
      "title": "Targeting Surgeons' Decision-Making for Cleft Lip Surgery",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Cleft Palate",
        "Cleft Lip"
      ],
      "interventions": [
        {
          "name": "Static Images and Facial Videos",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Tufts University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "0 Months",
        "maximum_age": "21 Years",
        "sex": "ALL",
        "summary": "0 Months to 21 Years"
      },
      "enrollment_count": 48,
      "start_date": "2018-01-31",
      "completion_date": "2025-08-31",
      "has_results": false,
      "last_update_posted_date": "2024-08-28",
      "last_synced_at": "2026-06-10T22:21:10.510Z",
      "location_count": 2,
      "location_summary": "Boston, Massachusetts • Chapel Hill, North Carolina",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        },
        {
          "city": "Chapel Hill",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03537976"
    },
    {
      "nct_id": "NCT04725370",
      "title": "Characterization of Cleft Lip and Palate Conditions in Guatemala",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Cleft Lip",
        "Cleft Palate",
        "Cleft Lip and Palate"
      ],
      "interventions": [
        {
          "name": "NA - survey instrument",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Children's Hospital of Philadelphia",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "0 Years",
        "maximum_age": "18 Years",
        "sex": "ALL",
        "summary": "0 Years to 18 Years"
      },
      "enrollment_count": 629,
      "start_date": "2017-10-30",
      "completion_date": "2020-03-13",
      "has_results": false,
      "last_update_posted_date": "2021-01-26",
      "last_synced_at": "2026-06-10T22:21:10.510Z",
      "location_count": 1,
      "location_summary": "Philadelphia, Pennsylvania",
      "locations": [
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04725370"
    },
    {
      "nct_id": "NCT04234971",
      "title": "Cost Effectiveness in Alveolar Bone Grafting in Patients With Cleft Lip and Palate",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Cleft Lip and Palate"
      ],
      "interventions": [
        {
          "name": "Intervention group (DBM/BMP)",
          "type": "DRUG"
        },
        {
          "name": "Control group(autologous ICBG)",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "The University of Texas Health Science Center, Houston",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "6 Years",
        "maximum_age": "15 Years",
        "sex": "ALL",
        "summary": "6 Years to 15 Years"
      },
      "enrollment_count": 40,
      "start_date": "2021-06-14",
      "completion_date": "2028-01-01",
      "has_results": false,
      "last_update_posted_date": "2026-02-19",
      "last_synced_at": "2026-06-10T22:21:10.510Z",
      "location_count": 1,
      "location_summary": "Houston, Texas",
      "locations": [
        {
          "city": "Houston",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04234971"
    }
  ]
}