{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Cleft+Lip+and+Cleft+Palate&page=2",
    "query": {
      "condition": "Cleft Lip and Cleft Palate",
      "page": 2
    },
    "page_size": 10
  },
  "pagination": {
    "page": 2,
    "page_size": 10,
    "total_count": 10,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Cleft+Lip+and+Cleft+Palate&page=1&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-05-22T09:11:35.935Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT07219901",
      "title": "Early Intervention in Infants With Unrepaired Cleft Palate: Language, Palatal Function, and Articulation.",
      "overall_status": "NOT_YET_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Cleft Lip and Cleft Palate",
        "Cleft Lip Palate",
        "Cleft Lip and/or Palate",
        "Cleft Palate",
        "Cleft Palate Children",
        "Cleft Palates",
        "Cleft Palate Repair"
      ],
      "interventions": [
        {
          "name": "Early intervention for language, articulation and palatal function skills",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Old Dominion University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "6 Months",
        "maximum_age": "12 Months",
        "sex": "ALL",
        "summary": "6 Months to 12 Months"
      },
      "enrollment_count": 200,
      "start_date": "2025-10-21",
      "completion_date": "2027-01-31",
      "has_results": false,
      "last_update_posted_date": "2025-10-22",
      "last_synced_at": "2026-05-22T09:11:35.935Z",
      "location_count": 1,
      "location_summary": "Norfolk, Virginia",
      "locations": [
        {
          "city": "Norfolk",
          "state": "Virginia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07219901"
    },
    {
      "nct_id": "NCT01252264",
      "title": "FaceBase Biorepository",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Craniofacial Abnormalities",
        "Cleft Lip",
        "Cleft Palate"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Jeff Murray",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": "125 Years",
        "sex": "ALL",
        "summary": "Up to 125 Years"
      },
      "enrollment_count": 5000,
      "start_date": "2010-11",
      "completion_date": "2015-07",
      "has_results": false,
      "last_update_posted_date": "2018-05-04",
      "last_synced_at": "2026-05-22T09:11:35.935Z",
      "location_count": 1,
      "location_summary": "Iowa City, Iowa",
      "locations": [
        {
          "city": "Iowa City",
          "state": "Iowa"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01252264"
    },
    {
      "nct_id": "NCT00340964",
      "title": "Positive Exposure: A Photography and Video Intervention for Individuals With Craniofacial Differences",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Craniofacial Differences"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "National Human Genome Research Institute (NHGRI)",
      "sponsor_class": "NIH",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "12 Years",
        "maximum_age": "20 Years",
        "sex": "ALL",
        "summary": "12 Years to 20 Years"
      },
      "enrollment_count": 44,
      "start_date": "2005-06-13",
      "completion_date": "2014-01-06",
      "has_results": false,
      "last_update_posted_date": "2019-12-12",
      "last_synced_at": "2026-05-22T09:11:35.935Z",
      "location_count": 1,
      "location_summary": "Bethesda, Maryland",
      "locations": [
        {
          "city": "Bethesda",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00340964"
    },
    {
      "nct_id": "NCT00397917",
      "title": "Oral Cleft Prevention Program",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Cleft Lip",
        "Cleft Palate"
      ],
      "interventions": [
        {
          "name": "Folic acid: 4 mg versus 0.4 mg per day",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of Iowa",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "16 Years",
        "maximum_age": "45 Years",
        "sex": "FEMALE",
        "summary": "16 Years to 45 Years · Female only"
      },
      "enrollment_count": 4000,
      "start_date": "2006-11",
      "completion_date": "2013-07",
      "has_results": false,
      "last_update_posted_date": "2017-03-31",
      "last_synced_at": "2026-05-22T09:11:35.935Z",
      "location_count": 1,
      "location_summary": "Iowa City, Iowa",
      "locations": [
        {
          "city": "Iowa City",
          "state": "Iowa"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00397917"
    },
    {
      "nct_id": "NCT06338319",
      "title": "Book Sharing for Toddlers With Clefts",
      "overall_status": "ENROLLING_BY_INVITATION",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Cleft Palate",
        "Cleft Lip and Palate"
      ],
      "interventions": [
        {
          "name": "Book-Sharing for Toddlers with Clefts (BOOST)",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Seattle Children's Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "20 Months",
        "maximum_age": "32 Months",
        "sex": "ALL",
        "summary": "20 Months to 32 Months"
      },
      "enrollment_count": 320,
      "start_date": "2024-05-01",
      "completion_date": "2028-08",
      "has_results": false,
      "last_update_posted_date": "2025-05-23",
      "last_synced_at": "2026-05-22T09:11:35.935Z",
      "location_count": 1,
      "location_summary": "Seattle, Washington",
      "locations": [
        {
          "city": "Seattle",
          "state": "Washington"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06338319"
    },
    {
      "nct_id": "NCT00004639",
      "title": "Cleft Palate Surgery and Speech Development",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Cleft Lip",
        "Cleft Palate"
      ],
      "interventions": [
        {
          "name": "Furlow double z-plasty palatoplasty palate repair",
          "type": "PROCEDURE"
        },
        {
          "name": "Von Langenbeck palatoplasty palate repair",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "University of Florida",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 475,
      "start_date": "1996-02",
      "completion_date": "2007-04",
      "has_results": false,
      "last_update_posted_date": "2011-09-20",
      "last_synced_at": "2026-05-22T09:11:35.935Z",
      "location_count": 1,
      "location_summary": "Gainesville, Florida",
      "locations": [
        {
          "city": "Gainesville",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00004639"
    },
    {
      "nct_id": "NCT04234971",
      "title": "Cost Effectiveness in Alveolar Bone Grafting in Patients With Cleft Lip and Palate",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Cleft Lip and Palate"
      ],
      "interventions": [
        {
          "name": "Intervention group (DBM/BMP)",
          "type": "DRUG"
        },
        {
          "name": "Control group(autologous ICBG)",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "The University of Texas Health Science Center, Houston",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "6 Years",
        "maximum_age": "15 Years",
        "sex": "ALL",
        "summary": "6 Years to 15 Years"
      },
      "enrollment_count": 40,
      "start_date": "2021-06-14",
      "completion_date": "2028-01-01",
      "has_results": false,
      "last_update_posted_date": "2026-02-19",
      "last_synced_at": "2026-05-22T09:11:35.935Z",
      "location_count": 1,
      "location_summary": "Houston, Texas",
      "locations": [
        {
          "city": "Houston",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04234971"
    },
    {
      "nct_id": "NCT04455035",
      "title": "DynaCleft® Effects on Soft Tissues and on Quality of Life for Incomplete Unilateral Cleft Lip Infants",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Cleft Lip and Palate"
      ],
      "interventions": [
        {
          "name": "Comparator: Retrospective Group(Control)",
          "type": "OTHER"
        },
        {
          "name": "Prospective Group",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "OTHER",
        "DEVICE"
      ],
      "sponsor": "The University of Texas Health Science Center, Houston",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": "6 Months",
        "sex": "ALL",
        "summary": "Up to 6 Months"
      },
      "enrollment_count": 24,
      "start_date": "2020-09-21",
      "completion_date": "2021-04-06",
      "has_results": true,
      "last_update_posted_date": "2024-12-30",
      "last_synced_at": "2026-05-22T09:11:35.935Z",
      "location_count": 1,
      "location_summary": "Houston, Texas",
      "locations": [
        {
          "city": "Houston",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04455035"
    },
    {
      "nct_id": "NCT04771156",
      "title": "Ketorolac in Palatoplasty",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Cleft Lip and Palate"
      ],
      "interventions": [
        {
          "name": "Ketorolac",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "The University of Texas Health Science Center, Houston",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "6 Months",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "6 Months and older"
      },
      "enrollment_count": 74,
      "start_date": "2021-09-17",
      "completion_date": "2027-04-01",
      "has_results": false,
      "last_update_posted_date": "2026-02-19",
      "last_synced_at": "2026-05-22T09:11:35.935Z",
      "location_count": 1,
      "location_summary": "Houston, Texas",
      "locations": [
        {
          "city": "Houston",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04771156"
    },
    {
      "nct_id": "NCT07133464",
      "title": "CDH1-associated Blepharocheilodontic Syndrome Registry",
      "overall_status": "RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Blepharocheilodontic Syndrome"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Ohio State University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 100,
      "start_date": "2025-06-17",
      "completion_date": "2040-01",
      "has_results": false,
      "last_update_posted_date": "2025-08-21",
      "last_synced_at": "2026-05-22T09:11:35.935Z",
      "location_count": 1,
      "location_summary": "Columbus, Ohio",
      "locations": [
        {
          "city": "Columbus",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07133464"
    }
  ]
}