{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Clostridium+Difficile+Infection&page=2",
    "query": {
      "condition": "Clostridium Difficile Infection",
      "page": 2
    },
    "page_size": 10
  },
  "pagination": {
    "page": 2,
    "page_size": 10,
    "total_count": 10,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Clostridium+Difficile+Infection&page=1&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-05-22T07:50:12.097Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT01222702",
      "title": "Efficacy, Safety and Tolerability of Cadazolid in Subjects With Clostridium Difficile Associated Diarrhea (CDAD)",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Clostridium Difficile Infection"
      ],
      "interventions": [
        {
          "name": "Cadazolid",
          "type": "DRUG"
        },
        {
          "name": "Vancomycin",
          "type": "DRUG"
        },
        {
          "name": "Placebo-matching cadazolid",
          "type": "DRUG"
        },
        {
          "name": "Placebo-matching vancomycin",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Actelion",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 84,
      "start_date": "2011-01-25",
      "completion_date": "2012-11-12",
      "has_results": false,
      "last_update_posted_date": "2017-06-14",
      "last_synced_at": "2026-05-22T07:50:12.097Z",
      "location_count": 11,
      "location_summary": "Newark, Delaware • Jacksonville, Florida • Orlando, Florida + 8 more",
      "locations": [
        {
          "city": "Newark",
          "state": "Delaware"
        },
        {
          "city": "Jacksonville",
          "state": "Florida"
        },
        {
          "city": "Orlando",
          "state": "Florida"
        },
        {
          "city": "Decatur",
          "state": "Georgia"
        },
        {
          "city": "Marietta",
          "state": "Georgia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01222702"
    },
    {
      "nct_id": "NCT06258551",
      "title": "Dynamics of Colonization and Infection by Multidrug-Resistant Pathogens in Immunocompromised and Critically Ill Patients",
      "overall_status": "RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Antimicrobial Drug Resistance",
        "Antibiotic Resistant Infection",
        "Clostridium Difficile",
        "Carbapenem-Resistant Enterobacteriaceae Infection",
        "Extended Spectrum Beta-Lactamase Producing Bacteria Infection",
        "Vancomycin Resistant Enterococci Infection",
        "Carbapenem Resistant Bacterial Infection",
        "Vancomycin-Resistant Enterococcal Infection"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "The Methodist Hospital Research Institute",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 1000,
      "start_date": "2020-12-08",
      "completion_date": "2026-06",
      "has_results": false,
      "last_update_posted_date": "2024-02-14",
      "last_synced_at": "2026-05-22T07:50:12.097Z",
      "location_count": 2,
      "location_summary": "Houston, Texas",
      "locations": [
        {
          "city": "Houston",
          "state": "Texas"
        },
        {
          "city": "Houston",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06258551"
    },
    {
      "nct_id": "NCT00350298",
      "title": "Study of the Clinical Effectiveness of a Human Monoclonal Antibody to C. Difficile Toxin A and Toxin B in Patients With Clostridium Difficile Associated Disease",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Clostridium Infections"
      ],
      "interventions": [
        {
          "name": "GS-CDA1/MDX-1388",
          "type": "BIOLOGICAL"
        },
        {
          "name": "normal saline",
          "type": "BIOLOGICAL"
        }
      ],
      "intervention_types": [
        "BIOLOGICAL"
      ],
      "sponsor": "MassBiologics",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 200,
      "start_date": "2006-07-20",
      "completion_date": "2008-06-25",
      "has_results": true,
      "last_update_posted_date": "2021-02-09",
      "last_synced_at": "2026-05-22T07:50:12.097Z",
      "location_count": 22,
      "location_summary": "Los Angeles, California • Oakland, California • Newark, Delaware + 18 more",
      "locations": [
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Oakland",
          "state": "California"
        },
        {
          "city": "Newark",
          "state": "Delaware"
        },
        {
          "city": "Tampa",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00350298"
    },
    {
      "nct_id": "NCT03462459",
      "title": "Efficacy of Oral Vancomycin Prophylaxis for Prevention of Recurrent Clostridium Difficile Infection",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Recurrent Clostridium Difficile Infection",
        "Clostridium Difficile Infection",
        "CDI",
        "C.Difficile Diarrhea",
        "C. Diff Colitis",
        "C.Difficile Colitis"
      ],
      "interventions": [
        {
          "name": "Vancomycin",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of Wisconsin, Madison",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 79,
      "start_date": "2018-05-21",
      "completion_date": "2023-07-06",
      "has_results": true,
      "last_update_posted_date": "2025-05-25",
      "last_synced_at": "2026-05-22T07:50:12.097Z",
      "location_count": 2,
      "location_summary": "Madison, Wisconsin • Milwaukee, Wisconsin",
      "locations": [
        {
          "city": "Madison",
          "state": "Wisconsin"
        },
        {
          "city": "Milwaukee",
          "state": "Wisconsin"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03462459"
    },
    {
      "nct_id": "NCT06469151",
      "title": "A Study to Evaluate the Safety, Tolerability and Pharmacokinetics of AZD5148 in Healthy Adults",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Healthy Participants"
      ],
      "interventions": [
        {
          "name": "AZD5148",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "AstraZeneca",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 84,
      "start_date": "2024-06-24",
      "completion_date": "2025-10-22",
      "has_results": false,
      "last_update_posted_date": "2025-11-10",
      "last_synced_at": "2026-05-22T07:50:12.097Z",
      "location_count": 4,
      "location_summary": "Anniston, Alabama • Glendale, California • Baltimore, Maryland + 1 more",
      "locations": [
        {
          "city": "Anniston",
          "state": "Alabama"
        },
        {
          "city": "Glendale",
          "state": "California"
        },
        {
          "city": "Baltimore",
          "state": "Maryland"
        },
        {
          "city": "San Antonio",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06469151"
    },
    {
      "nct_id": "NCT03617172",
      "title": "PROCLAIM -- Misoprostol in the Prevention of Recurrent CDI Prevent Recurrence of Clostridium Difficile Infection With Misoprostol",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Clostridium Difficile"
      ],
      "interventions": [
        {
          "name": "Misoprostol 100Mcg Tab",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DRUG",
        "OTHER"
      ],
      "sponsor": "Vanderbilt University Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 6,
      "start_date": "2018-11-26",
      "completion_date": "2021-09-22",
      "has_results": true,
      "last_update_posted_date": "2022-11-30",
      "last_synced_at": "2026-05-22T07:50:12.097Z",
      "location_count": 3,
      "location_summary": "St Louis, Missouri • Chapel Hill, North Carolina • Nashville, Tennessee",
      "locations": [
        {
          "city": "St Louis",
          "state": "Missouri"
        },
        {
          "city": "Chapel Hill",
          "state": "North Carolina"
        },
        {
          "city": "Nashville",
          "state": "Tennessee"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03617172"
    },
    {
      "nct_id": "NCT03562741",
      "title": "Outcomes and Data Collection for Fecal Microbiota Transplantation for the Treatment of Recurrent Clostridium Difficile",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Clostridium Difficile Infection Recurrence",
        "Clostridium Difficile Infection"
      ],
      "interventions": [
        {
          "name": "Fecal Microbiota Transplantation",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Krunal Patel",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "16 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "16 Years and older"
      },
      "enrollment_count": 500,
      "start_date": "2014-01-16",
      "completion_date": "2029-01-16",
      "has_results": false,
      "last_update_posted_date": "2026-02-20",
      "last_synced_at": "2026-05-22T07:50:12.097Z",
      "location_count": 1,
      "location_summary": "Worcester, Massachusetts",
      "locations": [
        {
          "city": "Worcester",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03562741"
    },
    {
      "nct_id": "NCT04014608",
      "title": "Protocol for Admission Toxigenic C. Difficile Surveillance",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Clostridium Difficile Infection"
      ],
      "interventions": [
        {
          "name": "Standard Practice to Prevent Hospital Onset CDI",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Endeavor Health",
      "sponsor_class": "OTHER",
      "healthy_volunteers": null,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": "1 Year",
        "sex": "ALL",
        "summary": "Up to 1 Year"
      },
      "enrollment_count": 148549,
      "start_date": "2016-07-01",
      "completion_date": "2018-12-31",
      "has_results": false,
      "last_update_posted_date": "2019-09-10",
      "last_synced_at": "2026-05-22T07:50:12.097Z",
      "location_count": 1,
      "location_summary": "Evanston, Illinois",
      "locations": [
        {
          "city": "Evanston",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04014608"
    },
    {
      "nct_id": "NCT00304408",
      "title": "Association Between Response to Treatment of C. Diff Colitis and Anti-C.Diff Toxin Antibody",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Clostridium Enterocolitis",
        "Pseudomembranous Colitis",
        "Antibiotic-Associated Colitis"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Michael E. DeBakey VA Medical Center",
      "sponsor_class": "FED",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 10,
      "start_date": "2005-01",
      "completion_date": "2008-01",
      "has_results": false,
      "last_update_posted_date": "2010-09-10",
      "last_synced_at": "2026-05-22T07:50:12.097Z",
      "location_count": 1,
      "location_summary": "Houston, Texas",
      "locations": [
        {
          "city": "Houston",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00304408"
    },
    {
      "nct_id": "NCT03970200",
      "title": "Penn Microbiome Therapy (PMT) for Severe-Clostridium Difficile Infection (CDI)",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Severe Clostridium Difficile Infection",
        "Severe-Complicated/Fulminant Clostridium Difficile Infection"
      ],
      "interventions": [
        {
          "name": "Penn Microbiome Therapy - 001",
          "type": "DRUG"
        },
        {
          "name": "Penn Microbiome Therapy - 002",
          "type": "DRUG"
        },
        {
          "name": "Penn Microbiome Therapy - 003",
          "type": "DRUG"
        },
        {
          "name": "Antibiotics",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of Pennsylvania",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 15,
      "start_date": "2020-01-16",
      "completion_date": "2022-05-14",
      "has_results": true,
      "last_update_posted_date": "2023-10-30",
      "last_synced_at": "2026-05-22T07:50:12.097Z",
      "location_count": 1,
      "location_summary": "Philadelphia, Pennsylvania",
      "locations": [
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03970200"
    }
  ]
}