{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Coffee&page=2",
    "query": {
      "condition": "Coffee",
      "page": 2
    },
    "page_size": 10
  },
  "pagination": {
    "page": 2,
    "page_size": 10,
    "total_count": 10,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Coffee&page=1&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-06-26T09:50:44.446Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT05692024",
      "title": "COffee and Metabolites Modulating the Gut MicrobiomE in Colorectal caNCER",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1",
        "PHASE2"
      ],
      "conditions": [
        "Colorectal Cancer",
        "Coffee",
        "Gastrointestinal Microbiome",
        "Stenosis",
        "Fibrosis, Liver",
        "Ultrasound Elastography",
        "Proton Magnetic Resonance Spectroscopy"
      ],
      "interventions": [
        {
          "name": "Nestlé NESCAFÉ® TASTER'S CHOICE® House Blend capsule.",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Massachusetts General Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 80,
      "start_date": "2024-03-21",
      "completion_date": "2028-08-31",
      "has_results": false,
      "last_update_posted_date": "2026-05-05",
      "last_synced_at": "2026-06-26T09:50:44.446Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05692024"
    },
    {
      "nct_id": "NCT04180787",
      "title": "Effects of a Caffeine- and Protein-Containing Coffee Beverage on Metabolism and Muscular Performance",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Exercise Performance",
        "Metabolism"
      ],
      "interventions": [
        {
          "name": "Beverage Consumption",
          "type": "DIETARY_SUPPLEMENT"
        }
      ],
      "intervention_types": [
        "DIETARY_SUPPLEMENT"
      ],
      "sponsor": "Texas Tech University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "40 Years",
        "sex": "ALL",
        "summary": "18 Years to 40 Years"
      },
      "enrollment_count": 19,
      "start_date": "2019-12-05",
      "completion_date": "2020-03-09",
      "has_results": false,
      "last_update_posted_date": "2020-05-07",
      "last_synced_at": "2026-06-26T09:50:44.446Z",
      "location_count": 1,
      "location_summary": "Lubbock, Texas",
      "locations": [
        {
          "city": "Lubbock",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04180787"
    },
    {
      "nct_id": "NCT01707056",
      "title": "The Effect of Coffee on the Absorption of Thyroid Hormone in Patients With Thyroid Carcinoma",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Thyroid Carcinoma",
        "Hypothyroidism"
      ],
      "interventions": [
        {
          "name": "Black Coffee",
          "type": "OTHER"
        },
        {
          "name": "Coffee with Milk",
          "type": "OTHER"
        },
        {
          "name": "Black Tea",
          "type": "OTHER"
        },
        {
          "name": "Water",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Medstar Health Research Institute",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "60 Years",
        "sex": "ALL",
        "summary": "18 Years to 60 Years"
      },
      "enrollment_count": 0,
      "start_date": "2012-09",
      "completion_date": "2016-06",
      "has_results": false,
      "last_update_posted_date": "2021-02-17",
      "last_synced_at": "2026-06-26T09:50:44.446Z",
      "location_count": 3,
      "location_summary": "Washington D.C., District of Columbia • Leonardtown, Maryland",
      "locations": [
        {
          "city": "Washington D.C.",
          "state": "District of Columbia"
        },
        {
          "city": "Washington D.C.",
          "state": "District of Columbia"
        },
        {
          "city": "Leonardtown",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01707056"
    },
    {
      "nct_id": "NCT02401776",
      "title": "Effect of Caffeine on Heart Function",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Fatigue",
        "Tachycardia"
      ],
      "interventions": [
        {
          "name": "Monster Energy Drink",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Coffee",
          "type": "DIETARY_SUPPLEMENT"
        }
      ],
      "intervention_types": [
        "DIETARY_SUPPLEMENT"
      ],
      "sponsor": "University of Texas at Austin",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "35 Years",
        "sex": "ALL",
        "summary": "18 Years to 35 Years"
      },
      "enrollment_count": 30,
      "start_date": "2014-03",
      "completion_date": "2015-12",
      "has_results": false,
      "last_update_posted_date": "2016-10-18",
      "last_synced_at": "2026-06-26T09:50:44.446Z",
      "location_count": 1,
      "location_summary": "Austin, Texas",
      "locations": [
        {
          "city": "Austin",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02401776"
    },
    {
      "nct_id": "NCT07641335",
      "title": "Effects of Caffeine on Chess Performance and Cognitive Function in Professional Chess Players",
      "overall_status": "NOT_YET_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Cognitive Performance",
        "Attention",
        "Reaction Time",
        "Caffeine"
      ],
      "interventions": [
        {
          "name": "Caffeinated Coffee",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Decaffeinated Coffee Placebo",
          "type": "DIETARY_SUPPLEMENT"
        }
      ],
      "intervention_types": [
        "DIETARY_SUPPLEMENT"
      ],
      "sponsor": "St. Louis University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "50 Years",
        "sex": "ALL",
        "summary": "18 Years to 50 Years"
      },
      "enrollment_count": 12,
      "start_date": "2026-06-15",
      "completion_date": "2027-08",
      "has_results": false,
      "last_update_posted_date": "2026-06-11",
      "last_synced_at": "2026-06-26T09:50:44.446Z",
      "location_count": 1,
      "location_summary": "St Louis, Missouri",
      "locations": [
        {
          "city": "St Louis",
          "state": "Missouri"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07641335"
    },
    {
      "nct_id": "NCT00932750",
      "title": "Study of Coffee Mannooligosaccharides for Weight Management",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Obesity"
      ],
      "interventions": [
        {
          "name": "Coffee mannooligosaccharide",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Coffee mannooligosaccharides",
          "type": "DIETARY_SUPPLEMENT"
        }
      ],
      "intervention_types": [
        "DIETARY_SUPPLEMENT"
      ],
      "sponsor": "Mondelēz International, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "20 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "20 Years to 65 Years"
      },
      "enrollment_count": 82,
      "start_date": "2006-09",
      "completion_date": "2007-11",
      "has_results": false,
      "last_update_posted_date": "2012-08-22",
      "last_synced_at": "2026-06-26T09:50:44.446Z",
      "location_count": 1,
      "location_summary": "New York, New York",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00932750"
    },
    {
      "nct_id": "NCT04805333",
      "title": "Phase 1 Dose Escalation of ArtemiCoffee",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Ovarian Cancer"
      ],
      "interventions": [
        {
          "name": "Artemisia annua 450mg",
          "type": "DRUG"
        },
        {
          "name": "Artemisia annua 900mg",
          "type": "DRUG"
        },
        {
          "name": "Artemisia annua 1350mg",
          "type": "DRUG"
        },
        {
          "name": "Artemisia annua 1800mg",
          "type": "DRUG"
        },
        {
          "name": "Artemisia annua - recommended phase II dose",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Frederick R. Ueland, M.D.",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "FEMALE",
        "summary": "18 Years and older · Female only"
      },
      "enrollment_count": 13,
      "start_date": "2021-03-26",
      "completion_date": "2025-02-04",
      "has_results": false,
      "last_update_posted_date": "2025-02-10",
      "last_synced_at": "2026-06-26T09:50:44.446Z",
      "location_count": 1,
      "location_summary": "Lexington, Kentucky",
      "locations": [
        {
          "city": "Lexington",
          "state": "Kentucky"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04805333"
    },
    {
      "nct_id": "NCT00336271",
      "title": "The Effects of Coffee",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Healthy Subjects"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "American University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 50,
      "start_date": "2006-04",
      "completion_date": "2007-03",
      "has_results": false,
      "last_update_posted_date": "2007-03-15",
      "last_synced_at": "2026-06-26T09:50:44.446Z",
      "location_count": 1,
      "location_summary": "Washington D.C., District of Columbia",
      "locations": [
        {
          "city": "Washington D.C.",
          "state": "District of Columbia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00336271"
    },
    {
      "nct_id": "NCT00305097",
      "title": "Effects of Caffeinated and Decaffeinated Coffee on Body Weight and Glucose Tolerance",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Overweight"
      ],
      "interventions": [
        {
          "name": "Decaffeinated coffee",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Caffeinated coffee",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "No coffee",
          "type": "DIETARY_SUPPLEMENT"
        }
      ],
      "intervention_types": [
        "DIETARY_SUPPLEMENT"
      ],
      "sponsor": "National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)",
      "sponsor_class": "NIH",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 45,
      "start_date": "2006-05",
      "completion_date": "2008-09",
      "has_results": false,
      "last_update_posted_date": "2018-03-06",
      "last_synced_at": "2026-06-26T09:50:44.446Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00305097"
    },
    {
      "nct_id": "NCT04060225",
      "title": "Effects of High Caffeine Content Coffee on Blood Pressure in Young Adults",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "High Blood Pressure"
      ],
      "interventions": [
        {
          "name": "Coffee",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of Rochester",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "30 Years",
        "sex": "ALL",
        "summary": "18 Years to 30 Years"
      },
      "enrollment_count": 1,
      "start_date": "2019-12-02",
      "completion_date": "2019-12-19",
      "has_results": false,
      "last_update_posted_date": "2021-01-14",
      "last_synced_at": "2026-06-26T09:50:44.446Z",
      "location_count": 1,
      "location_summary": "Rochester, New York",
      "locations": [
        {
          "city": "Rochester",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04060225"
    }
  ]
}