{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Cognitive+Decline%2C+Mild",
    "query": {
      "condition": "Cognitive Decline, Mild"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 813,
    "total_pages": 82,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Cognitive+Decline%2C+Mild&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-07-23T08:21:15.984Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT00446394",
      "title": "Exercise and Activities for Independent Living With Mild Cognitive Impairment (MCI)",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Mild Cognitive Impairment",
        "Dementia"
      ],
      "interventions": [
        {
          "name": "Resources and Activities for Life Long Independence (RALLI)",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Social Walking program (SW)",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of Washington",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "70 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "70 Years and older"
      },
      "enrollment_count": 181,
      "start_date": "2007-06",
      "completion_date": "2012-10",
      "has_results": false,
      "last_update_posted_date": "2012-10-19",
      "last_synced_at": "2026-07-23T08:21:15.984Z",
      "location_count": 1,
      "location_summary": "Seattle, Washington",
      "locations": [
        {
          "city": "Seattle",
          "state": "Washington"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00446394"
    },
    {
      "nct_id": "NCT02878486",
      "title": "Intervention to Reduce Sedentary Time",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Mild Cognitive Impairment"
      ],
      "interventions": [
        {
          "name": "Jawbone Up",
          "type": "DEVICE"
        },
        {
          "name": "Physical Activity Education",
          "type": "BEHAVIORAL"
        },
        {
          "name": "ActivPAL",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "BEHAVIORAL"
      ],
      "sponsor": "University of Kansas Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 6,
      "start_date": "2016-08",
      "completion_date": "2018-01",
      "has_results": true,
      "last_update_posted_date": "2019-07-29",
      "last_synced_at": "2026-07-23T08:21:15.984Z",
      "location_count": 1,
      "location_summary": "Kansas City, Kansas",
      "locations": [
        {
          "city": "Kansas City",
          "state": "Kansas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02878486"
    },
    {
      "nct_id": "NCT01687153",
      "title": "A Study of Brain Aging in Vietnam War Veterans",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Traumatic Brain Injury",
        "Post Traumatic Stress Disorder",
        "Alzheimer's Disease",
        "Mild Cognitive Impairment"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "University of Southern California",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "50 Years",
        "maximum_age": "90 Years",
        "sex": "ALL",
        "summary": "50 Years to 90 Years"
      },
      "enrollment_count": 289,
      "start_date": "2012-10",
      "completion_date": "2021-09-21",
      "has_results": false,
      "last_update_posted_date": "2021-11-29",
      "last_synced_at": "2026-07-23T08:21:15.984Z",
      "location_count": 19,
      "location_summary": "Sun City, Arizona • Irvine, California • La Jolla, California + 14 more",
      "locations": [
        {
          "city": "Sun City",
          "state": "Arizona"
        },
        {
          "city": "Irvine",
          "state": "California"
        },
        {
          "city": "La Jolla",
          "state": "California"
        },
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Palo Alto",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01687153"
    },
    {
      "nct_id": "NCT07701668",
      "title": "AI-CONECT: A Conversational AI for Early Dementia Prevention in Socially-Isolated Older Adults",
      "overall_status": "NOT_YET_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Mild Cognitive Impairment (MCI)",
        "Social Isolation"
      ],
      "interventions": [
        {
          "name": "AI-based conversational intervention",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Massachusetts General Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "75 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "75 Years and older"
      },
      "enrollment_count": 80,
      "start_date": "2026-07-30",
      "completion_date": "2028-03-31",
      "has_results": false,
      "last_update_posted_date": "2026-07-14",
      "last_synced_at": "2026-07-23T08:21:15.984Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07701668"
    },
    {
      "nct_id": "NCT07284290",
      "title": "Elucidating the Role of Cholinergic Degeneration in Cognitive Fluctuations in Lewy Body Dementia",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Dementia With Lewy Bodies",
        "Parkinson Disease Dementia",
        "Healthy Controls"
      ],
      "interventions": [
        {
          "name": "Syn-One skin biopsy",
          "type": "PROCEDURE"
        },
        {
          "name": "Multi modal MRI",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Assessment of dynamic EEG features over 48-hour periods across all study aims",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Plasma biomarkers",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Galantamine HBr extended-release 8mg capsules (8mg ER).",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "PROCEDURE",
        "DIAGNOSTIC_TEST",
        "DRUG"
      ],
      "sponsor": "Virginia Commonwealth University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "50 Years",
        "maximum_age": "89 Years",
        "sex": "ALL",
        "summary": "50 Years to 89 Years"
      },
      "enrollment_count": 120,
      "start_date": "2025-12-08",
      "completion_date": "2029-11",
      "has_results": false,
      "last_update_posted_date": "2026-03-06",
      "last_synced_at": "2026-07-23T08:21:15.984Z",
      "location_count": 1,
      "location_summary": "Richmond, Virginia",
      "locations": [
        {
          "city": "Richmond",
          "state": "Virginia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07284290"
    },
    {
      "nct_id": "NCT06223360",
      "title": "A Trial to Evaluate the Safety and Efficacy of Benfotiamine in Patients With Early Alzheimer's Disease (BenfoTeam)",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Alzheimer Disease"
      ],
      "interventions": [
        {
          "name": "Low Dose Benfotiamine",
          "type": "DRUG"
        },
        {
          "name": "High Dose Benfotiamine",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Alzheimer's Disease Cooperative Study (ADCS)",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "50 Years",
        "maximum_age": "89 Years",
        "sex": "ALL",
        "summary": "50 Years to 89 Years"
      },
      "enrollment_count": 406,
      "start_date": "2024-03-28",
      "completion_date": "2027-12-01",
      "has_results": false,
      "last_update_posted_date": "2026-06-04",
      "last_synced_at": "2026-07-23T08:21:15.984Z",
      "location_count": 47,
      "location_summary": "Phoenix, Arizona • Scottsdale, Arizona • Sun City, Arizona + 35 more",
      "locations": [
        {
          "city": "Phoenix",
          "state": "Arizona"
        },
        {
          "city": "Scottsdale",
          "state": "Arizona"
        },
        {
          "city": "Sun City",
          "state": "Arizona"
        },
        {
          "city": "Chula Vista",
          "state": "California"
        },
        {
          "city": "Irvine",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06223360"
    },
    {
      "nct_id": "NCT01891383",
      "title": "Clinical Characteristics of Dementias That Occur Remotely After Traumatic Brain Injury in Retired Military Personnel",
      "overall_status": "WITHDRAWN",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Dementia",
        "Traumatic Brain Injury (TBI)",
        "Mild Cognitive Impairment (MCI)",
        "Chronic Traumatic Encephalopathy (CTE)",
        "Post-traumatic Stress Disorder (PTSD)"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Uniformed Services University of the Health Sciences",
      "sponsor_class": "FED",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "50 Years",
        "maximum_age": "95 Years",
        "sex": "ALL",
        "summary": "50 Years to 95 Years"
      },
      "enrollment_count": 0,
      "start_date": "2013-07",
      "completion_date": "2016-08",
      "has_results": false,
      "last_update_posted_date": "2019-01-18",
      "last_synced_at": "2026-07-23T08:21:15.984Z",
      "location_count": 2,
      "location_summary": "Yountville, California • Washington D.C., District of Columbia",
      "locations": [
        {
          "city": "Yountville",
          "state": "California"
        },
        {
          "city": "Washington D.C.",
          "state": "District of Columbia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01891383"
    },
    {
      "nct_id": "NCT05810454",
      "title": "iPACES v3 MCI NIA Protocol Copied for iPACES v4 PD NINDS",
      "overall_status": "NOT_YET_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Parkinson's Disease",
        "PD",
        "Mild Cognitive Impairment",
        "MCI"
      ],
      "interventions": [
        {
          "name": "iPACES (interactive Physical and Cognitive Exercise System)",
          "type": "DEVICE"
        },
        {
          "name": "PACE (Physical and Cognitive Exercise)",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "iPACES LLC",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "50 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "50 Years and older"
      },
      "enrollment_count": 120,
      "start_date": "2023-08",
      "completion_date": "2026-08",
      "has_results": false,
      "last_update_posted_date": "2023-04-12",
      "last_synced_at": "2026-07-23T08:21:15.984Z",
      "location_count": 1,
      "location_summary": "Clifton Park, New York",
      "locations": [
        {
          "city": "Clifton Park",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05810454"
    },
    {
      "nct_id": "NCT03657745",
      "title": "Alzheimer's Disease Treatment With Combination of 40Hz Light and Cognitive Therapy",
      "overall_status": "RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Alzheimer Disease",
        "Mild Cognitive Impairment",
        "Dementia",
        "Cognition Disorders in Old Age",
        "Cognitive Decline",
        "Cognitive Deterioration"
      ],
      "interventions": [
        {
          "name": "Combination of 40Hz light and cognitive therapy (ALZLIFE)",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Alzheimer's Light LLC",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "50 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "50 Years and older"
      },
      "enrollment_count": 2000,
      "start_date": "2018-01-01",
      "completion_date": "2029-12-31",
      "has_results": false,
      "last_update_posted_date": "2024-08-01",
      "last_synced_at": "2026-07-23T08:21:15.984Z",
      "location_count": 1,
      "location_summary": "Miami, Florida",
      "locations": [
        {
          "city": "Miami",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03657745"
    },
    {
      "nct_id": "NCT04114994",
      "title": "Longitudinal Cognitive Assessment by BoCA",
      "overall_status": "RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Alzheimer Disease",
        "Mild Cognitive Impairment",
        "Vascular Dementia",
        "Frontotemporal Dementia",
        "Parkinson Disease",
        "Multiple Sclerosis",
        "TBI"
      ],
      "interventions": [
        {
          "name": "Boston Cognitive Assessment (BoCA)",
          "type": "DIAGNOSTIC_TEST"
        }
      ],
      "intervention_types": [
        "DIAGNOSTIC_TEST"
      ],
      "sponsor": "Alzheimer's Light LLC",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "50 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "50 Years and older"
      },
      "enrollment_count": 10000,
      "start_date": "2019-10-01",
      "completion_date": "2029-10-01",
      "has_results": false,
      "last_update_posted_date": "2024-08-01",
      "last_synced_at": "2026-07-23T08:21:15.984Z",
      "location_count": 1,
      "location_summary": "Miami, Florida",
      "locations": [
        {
          "city": "Miami",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04114994"
    }
  ]
}