{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Cognitive+Function+Decline",
    "query": {
      "condition": "Cognitive Function Decline"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 296,
    "total_pages": 30,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Cognitive+Function+Decline&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-07-22T15:01:38.627Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT06850870",
      "title": "Door-Through-Door Companion Rideshare Technology for Individuals With Alzheimer's Disease and Related Dementias (AD/ADRD)",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Alzheimer Disease or Associated Disorder",
        "Dementia",
        "Cognitive Decline"
      ],
      "interventions": [
        {
          "name": "Door-through-door companion rideshare",
          "type": "OTHER"
        },
        {
          "name": "Curb-to-curb rideshare services",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Onward Health, Inc",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "60 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "60 Years and older"
      },
      "enrollment_count": 120,
      "start_date": "2025-08-29",
      "completion_date": "2026-12-28",
      "has_results": false,
      "last_update_posted_date": "2026-07-21",
      "last_synced_at": "2026-07-22T15:01:38.627Z",
      "location_count": 1,
      "location_summary": "San Leandro, California",
      "locations": [
        {
          "city": "San Leandro",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06850870"
    },
    {
      "nct_id": "NCT06987383",
      "title": "Vibegron for ENergy Thinking and Resilience in Aging",
      "overall_status": "NOT_YET_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Obesity"
      ],
      "interventions": [
        {
          "name": "Vibegron",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Wake Forest University Health Sciences",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "45 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "45 Years to 75 Years"
      },
      "enrollment_count": 40,
      "start_date": "2026-08",
      "completion_date": "2028-07",
      "has_results": false,
      "last_update_posted_date": "2026-02-23",
      "last_synced_at": "2026-07-22T15:01:38.627Z",
      "location_count": 1,
      "location_summary": "Winston-Salem, North Carolina",
      "locations": [
        {
          "city": "Winston-Salem",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06987383"
    },
    {
      "nct_id": "NCT05810454",
      "title": "iPACES v3 MCI NIA Protocol Copied for iPACES v4 PD NINDS",
      "overall_status": "NOT_YET_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Parkinson's Disease",
        "PD",
        "Mild Cognitive Impairment",
        "MCI"
      ],
      "interventions": [
        {
          "name": "iPACES (interactive Physical and Cognitive Exercise System)",
          "type": "DEVICE"
        },
        {
          "name": "PACE (Physical and Cognitive Exercise)",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "iPACES LLC",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "50 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "50 Years and older"
      },
      "enrollment_count": 120,
      "start_date": "2023-08",
      "completion_date": "2026-08",
      "has_results": false,
      "last_update_posted_date": "2023-04-12",
      "last_synced_at": "2026-07-22T15:01:38.627Z",
      "location_count": 1,
      "location_summary": "Clifton Park, New York",
      "locations": [
        {
          "city": "Clifton Park",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05810454"
    },
    {
      "nct_id": "NCT03657745",
      "title": "Alzheimer's Disease Treatment With Combination of 40Hz Light and Cognitive Therapy",
      "overall_status": "RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Alzheimer Disease",
        "Mild Cognitive Impairment",
        "Dementia",
        "Cognition Disorders in Old Age",
        "Cognitive Decline",
        "Cognitive Deterioration"
      ],
      "interventions": [
        {
          "name": "Combination of 40Hz light and cognitive therapy (ALZLIFE)",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Alzheimer's Light LLC",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "50 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "50 Years and older"
      },
      "enrollment_count": 2000,
      "start_date": "2018-01-01",
      "completion_date": "2029-12-31",
      "has_results": false,
      "last_update_posted_date": "2024-08-01",
      "last_synced_at": "2026-07-22T15:01:38.627Z",
      "location_count": 1,
      "location_summary": "Miami, Florida",
      "locations": [
        {
          "city": "Miami",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03657745"
    },
    {
      "nct_id": "NCT06665022",
      "title": "Neuromodulation Effects in Older Adults",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Cognitive Impairment",
        "Cognitive Decline"
      ],
      "interventions": [
        {
          "name": "Active tDCS",
          "type": "DEVICE"
        },
        {
          "name": "Sham tDCS",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "University of Florida",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "60 Years",
        "maximum_age": "95 Years",
        "sex": "ALL",
        "summary": "60 Years to 95 Years"
      },
      "enrollment_count": 0,
      "start_date": "2024-12-01",
      "completion_date": "2024-12-01",
      "has_results": false,
      "last_update_posted_date": "2024-11-21",
      "last_synced_at": "2026-07-22T15:01:38.627Z",
      "location_count": 1,
      "location_summary": "Gainesville, Florida",
      "locations": [
        {
          "city": "Gainesville",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06665022"
    },
    {
      "nct_id": "NCT05741853",
      "title": "Cognitive Reserve and Response to Speech-Language Intervention in Bilingual Speakers With Primary Progressive Aphasia",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Primary Progressive Aphasia",
        "Dementia",
        "Dementia, Frontotemporal",
        "Alzheimer Disease",
        "Neurodegenerative Diseases",
        "Frontotemporal Lobar Degeneration",
        "Apraxia, Motor",
        "Dysarthria",
        "Communication Disorders",
        "Language Disorders",
        "Speech Disorders",
        "Neurocognitive Disorders",
        "Aphasia",
        "Bilingual Aphasia"
      ],
      "interventions": [
        {
          "name": "Video-Implemented Script Training for Aphasia (VISTA)",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Lexical Retrieval Training (LRT)",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Stephanie Grasso",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "40 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "40 Years and older"
      },
      "enrollment_count": 60,
      "start_date": "2023-05-01",
      "completion_date": "2027-11-30",
      "has_results": false,
      "last_update_posted_date": "2026-06-10",
      "last_synced_at": "2026-07-22T15:01:38.627Z",
      "location_count": 1,
      "location_summary": "Austin, Texas",
      "locations": [
        {
          "city": "Austin",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05741853"
    },
    {
      "nct_id": "NCT03733418",
      "title": "Vitamin D to Improve Outcomes by Leveraging Early Treatment: Long-term Brain Outcomes in Vitamin D Deficient Patients",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Cognitive Decline"
      ],
      "interventions": [
        {
          "name": "540,000 IU vitamin D3",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Vanderbilt University Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 95,
      "start_date": "2018-11-01",
      "completion_date": "2020-02-21",
      "has_results": true,
      "last_update_posted_date": "2024-10-21",
      "last_synced_at": "2026-07-22T15:01:38.627Z",
      "location_count": 7,
      "location_summary": "Aurora, Colorado • Boston, Massachusetts • New York, New York + 3 more",
      "locations": [
        {
          "city": "Aurora",
          "state": "Colorado"
        },
        {
          "city": "Boston",
          "state": "Massachusetts"
        },
        {
          "city": "Boston",
          "state": "Massachusetts"
        },
        {
          "city": "New York",
          "state": "New York"
        },
        {
          "city": "Portland",
          "state": "Oregon"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03733418"
    },
    {
      "nct_id": "NCT03162913",
      "title": "The Effects of Strawberry Supplementation on Memory and Gait Among Over-weight Older Adults",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Aging",
        "Age-related Cognitive Decline",
        "Obesity"
      ],
      "interventions": [
        {
          "name": "Strawberry",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Placebo",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DIETARY_SUPPLEMENT",
        "OTHER"
      ],
      "sponsor": "USDA Human Nutrition Research Center on Aging",
      "sponsor_class": "FED",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "55 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "55 Years to 75 Years"
      },
      "enrollment_count": 47,
      "start_date": "2017-10-01",
      "completion_date": "2023-10-20",
      "has_results": false,
      "last_update_posted_date": "2024-03-28",
      "last_synced_at": "2026-07-22T15:01:38.627Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03162913"
    },
    {
      "nct_id": "NCT02814526",
      "title": "Exercise in Adults With Mild Memory Problems",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Mild Cognitive Impairment",
        "Cognitive Decline",
        "Memory Impairment"
      ],
      "interventions": [
        {
          "name": "Aerobic exercise",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Stretching/balance/range of motion exercise",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Alzheimer's Disease Cooperative Study (ADCS)",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "65 Years",
        "maximum_age": "89 Years",
        "sex": "ALL",
        "summary": "65 Years to 89 Years"
      },
      "enrollment_count": 296,
      "start_date": "2016-09-13",
      "completion_date": "2021-12-19",
      "has_results": true,
      "last_update_posted_date": "2023-02-15",
      "last_synced_at": "2026-07-22T15:01:38.627Z",
      "location_count": 14,
      "location_summary": "Irvine, California • Palo Alto, California • New Haven, Connecticut + 10 more",
      "locations": [
        {
          "city": "Irvine",
          "state": "California"
        },
        {
          "city": "Palo Alto",
          "state": "California"
        },
        {
          "city": "New Haven",
          "state": "Connecticut"
        },
        {
          "city": "Atlanta",
          "state": "Georgia"
        },
        {
          "city": "Chicago",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02814526"
    },
    {
      "nct_id": "NCT03737825",
      "title": "Computerized Cognitive Training in MS",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Multiple Sclerosis",
        "Cognitive Decline"
      ],
      "interventions": [
        {
          "name": "Computerized gaming rehabilitation Program 1",
          "type": "DEVICE"
        },
        {
          "name": "Computerized gaming rehabilitation Program 2",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "University of California, San Francisco",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "60 Years",
        "sex": "ALL",
        "summary": "18 Years to 60 Years"
      },
      "enrollment_count": 2,
      "start_date": "2019-04-25",
      "completion_date": "2025-02-12",
      "has_results": false,
      "last_update_posted_date": "2026-04-06",
      "last_synced_at": "2026-07-22T15:01:38.627Z",
      "location_count": 1,
      "location_summary": "San Francisco, California",
      "locations": [
        {
          "city": "San Francisco",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03737825"
    }
  ]
}