{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Cognitive+Functioning&page=38",
    "query": {
      "condition": "Cognitive Functioning",
      "page": 38
    },
    "page_size": 10
  },
  "pagination": {
    "page": 38,
    "page_size": 10,
    "total_count": 1065,
    "total_pages": 107,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Cognitive+Functioning&page=39&page_size=10",
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Cognitive+Functioning&page=37&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-10-20T18:18:48.160Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT07202000",
      "title": "EXercise and Activin Inhibition to Modulate InflammatioN Effects on Heart Failure and Cognition (EXAMINE-HFC)",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Heart Failure With Preserved Ejection Fraction"
      ],
      "interventions": [
        {
          "name": "Activin ligand-trap biological therapy",
          "type": "DRUG"
        },
        {
          "name": "Placebo, Normal Saline",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Massachusetts General Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "40 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "40 Years and older"
      },
      "enrollment_count": 48,
      "start_date": "2026-06-03",
      "completion_date": "2027-08",
      "has_results": false,
      "last_update_posted_date": "2026-07-09",
      "last_synced_at": "2026-10-20T18:18:48.160Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07202000"
    },
    {
      "nct_id": "NCT05501249",
      "title": "Aquatic Exercise for Cognition and Mobility in Older Adults",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Aging Well",
        "Aging Problems",
        "Cognitive Change",
        "Gait, Unsteady",
        "Mobility Limitation"
      ],
      "interventions": [
        {
          "name": "Aquatic Integrated Cognitive Motor Training",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Emily Dunlap",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "65 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "65 Years and older"
      },
      "enrollment_count": 25,
      "start_date": "2022-02-01",
      "completion_date": "2022-12-12",
      "has_results": false,
      "last_update_posted_date": "2023-03-01",
      "last_synced_at": "2026-10-20T18:18:48.160Z",
      "location_count": 1,
      "location_summary": "Austin, Texas",
      "locations": [
        {
          "city": "Austin",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05501249"
    },
    {
      "nct_id": "NCT06735599",
      "title": "Wild Blueberries for Gut, Brain, and Heart Health in Adults With High Blood Pressure",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Hypertension (Without Type 2 Diabetes Mellitus)",
        "High Blood Pressure",
        "Male",
        "Female",
        "Adult",
        "Cognition",
        "Endothelial Function (Reactive Hyperemia)",
        "Oxidative Stress",
        "Diet",
        "Overweight",
        "Body Composition Measurement",
        "Gut Microbiome",
        "Arterial Stiffness",
        "Caucasian Whites",
        "Inflammation",
        "Microvascular Function"
      ],
      "interventions": [
        {
          "name": "Wild Blueberry",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Placebo",
          "type": "DIETARY_SUPPLEMENT"
        }
      ],
      "intervention_types": [
        "DIETARY_SUPPLEMENT"
      ],
      "sponsor": "Georgia State University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "45 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "45 Years to 65 Years"
      },
      "enrollment_count": 40,
      "start_date": "2024-09-17",
      "completion_date": "2027-01-01",
      "has_results": false,
      "last_update_posted_date": "2026-09-02",
      "last_synced_at": "2026-10-20T18:18:48.160Z",
      "location_count": 1,
      "location_summary": "Atlanta, Georgia",
      "locations": [
        {
          "city": "Atlanta",
          "state": "Georgia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06735599"
    },
    {
      "nct_id": "NCT04682977",
      "title": "Piloting the IPROACTIF Program to Preserve Functioning and Prevent Cognitive Decline",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Heart Disease (Coronary Artery Disease, Ischemic Heart Disease, Hypertensive Heart Disease)",
        "Uncontrolled Diabetes (HBA1c ≥ 10)"
      ],
      "interventions": [
        {
          "name": "IPROACTIF (Integrated PRimary Care and Occupational Therapy for Aging and Chronic Disease Treatment to preserve Independence and Functioning)",
          "type": "OTHER"
        },
        {
          "name": "Usual primary care services",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of Illinois at Chicago",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "55 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "55 Years and older"
      },
      "enrollment_count": 45,
      "start_date": "2021-08-11",
      "completion_date": "2024-03-01",
      "has_results": true,
      "last_update_posted_date": "2025-08-19",
      "last_synced_at": "2026-10-20T18:18:48.160Z",
      "location_count": 1,
      "location_summary": "Chicago, Illinois",
      "locations": [
        {
          "city": "Chicago",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04682977"
    },
    {
      "nct_id": "NCT06460181",
      "title": "Impact of Astaxanthin on Cognition in Recreationally Active Females",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Mental Fatigue"
      ],
      "interventions": [
        {
          "name": "Astaxanthin",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Placebo",
          "type": "DIETARY_SUPPLEMENT"
        }
      ],
      "intervention_types": [
        "DIETARY_SUPPLEMENT"
      ],
      "sponsor": "University of North Alabama",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "39 Years",
        "sex": "FEMALE",
        "summary": "18 Years to 39 Years · Female only"
      },
      "enrollment_count": 26,
      "start_date": "2024-08-01",
      "completion_date": "2024-12-14",
      "has_results": true,
      "last_update_posted_date": "2026-05-26",
      "last_synced_at": "2026-10-20T18:18:48.160Z",
      "location_count": 1,
      "location_summary": "Florence, Alabama",
      "locations": [
        {
          "city": "Florence",
          "state": "Alabama"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06460181"
    },
    {
      "nct_id": "NCT01167400",
      "title": "Cybercycling for Cognitive Health",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Cognitive Ability, General"
      ],
      "interventions": [
        {
          "name": "Cybercycling",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Traditional exercise",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Union College, New York",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "50 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "50 Years and older"
      },
      "enrollment_count": 63,
      "start_date": "2008-07",
      "completion_date": "2010-08",
      "has_results": false,
      "last_update_posted_date": "2014-09-05",
      "last_synced_at": "2026-10-20T18:18:48.160Z",
      "location_count": 8,
      "location_summary": "Colonie, New York • Malta, New York • Niskayuna, New York + 2 more",
      "locations": [
        {
          "city": "Colonie",
          "state": "New York"
        },
        {
          "city": "Malta",
          "state": "New York"
        },
        {
          "city": "Niskayuna",
          "state": "New York"
        },
        {
          "city": "Saratoga Springs",
          "state": "New York"
        },
        {
          "city": "Saratoga Springs",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01167400"
    },
    {
      "nct_id": "NCT04404621",
      "title": "Computer Presented and Physical Exercises to Maintain Cognitive Function and Emotional Health in Older Adults",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Cognitive Function",
        "Depression in Old Age"
      ],
      "interventions": [
        {
          "name": "Physical exercise (PE) training and computer-based brain (CBB)",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Yale University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "65 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "65 Years and older"
      },
      "enrollment_count": 34,
      "start_date": "2019-11-13",
      "completion_date": "2020-09-12",
      "has_results": false,
      "last_update_posted_date": "2021-06-14",
      "last_synced_at": "2026-10-20T18:18:48.160Z",
      "location_count": 1,
      "location_summary": "New Haven, Connecticut",
      "locations": [
        {
          "city": "New Haven",
          "state": "Connecticut"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04404621"
    },
    {
      "nct_id": "NCT00125957",
      "title": "The Effects of Wellbutrin (Bupropion) on Residual and Cognitive Symptoms in SSRI-treated Depression",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Depression",
        "Major Depressive Disorder",
        "Unipolar Depression"
      ],
      "interventions": [
        {
          "name": "Wellbutrin",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Mclean Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "70 Years",
        "sex": "ALL",
        "summary": "18 Years to 70 Years"
      },
      "enrollment_count": 32,
      "start_date": "2005-08",
      "completion_date": "2011-12",
      "has_results": true,
      "last_update_posted_date": "2014-08-06",
      "last_synced_at": "2026-10-20T18:18:48.160Z",
      "location_count": 1,
      "location_summary": "Belmont, Massachusetts",
      "locations": [
        {
          "city": "Belmont",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00125957"
    },
    {
      "nct_id": "NCT05631236",
      "title": "Promoting Cognitive Resilience and Reducing Frailty in Older Veterans With Bright Light Therapy",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Veteran Aged 65 and Older"
      ],
      "interventions": [
        {
          "name": "Bright Light Therapy (AYO Glasses)",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "VA Office of Research and Development",
      "sponsor_class": "FED",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "60 Years",
        "maximum_age": "85 Years",
        "sex": "ALL",
        "summary": "60 Years to 85 Years"
      },
      "enrollment_count": 43,
      "start_date": "2024-01-29",
      "completion_date": "2027-06-30",
      "has_results": false,
      "last_update_posted_date": "2026-07-21",
      "last_synced_at": "2026-10-20T18:18:48.160Z",
      "location_count": 1,
      "location_summary": "Kansas City, Missouri",
      "locations": [
        {
          "city": "Kansas City",
          "state": "Missouri"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05631236"
    },
    {
      "nct_id": "NCT01376349",
      "title": "Prasterone (Dehydroepiandrosterone) in Treating Postmenopausal Cancer Survivors With Vaginal Symptoms",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Breast Cancer",
        "Gynecologic Cancer"
      ],
      "interventions": [
        {
          "name": "prasterone",
          "type": "DRUG"
        },
        {
          "name": "placebo",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DRUG",
        "OTHER"
      ],
      "sponsor": "Alliance for Clinical Trials in Oncology",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "FEMALE",
        "summary": "18 Years and older · Female only"
      },
      "enrollment_count": 464,
      "start_date": "2011-07",
      "completion_date": "2017-11",
      "has_results": true,
      "last_update_posted_date": "2019-02-07",
      "last_synced_at": "2026-10-20T18:18:48.160Z",
      "location_count": 280,
      "location_summary": "Scottsdale, Arizona • Aurora, Colorado • Boulder, Colorado + 185 more",
      "locations": [
        {
          "city": "Scottsdale",
          "state": "Arizona"
        },
        {
          "city": "Aurora",
          "state": "Colorado"
        },
        {
          "city": "Boulder",
          "state": "Colorado"
        },
        {
          "city": "Colorado Springs",
          "state": "Colorado"
        },
        {
          "city": "Denver",
          "state": "Colorado"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01376349"
    }
  ]
}