{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Cognitive+Performance+in+Healthy+Volunteers",
    "query": {
      "condition": "Cognitive Performance in Healthy Volunteers"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 10,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-05-22T08:13:35.452Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT03008447",
      "title": "Crossover Study to Evaluate the Effect of Lemborexant Versus Placebo and Zolpidem on Postural Stability, Auditory Awakening Threshold, and Cognitive Performance in Healthy Subjects 55 Years and Older",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Healthy Subjects"
      ],
      "interventions": [
        {
          "name": "LEM5",
          "type": "DRUG"
        },
        {
          "name": "LEM10",
          "type": "DRUG"
        },
        {
          "name": "ZOL",
          "type": "DRUG"
        },
        {
          "name": "PBO",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Eisai Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "55 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "55 Years and older"
      },
      "enrollment_count": 60,
      "start_date": "2016-11-21",
      "completion_date": "2018-01-03",
      "has_results": false,
      "last_update_posted_date": "2019-08-01",
      "last_synced_at": "2026-05-22T08:13:35.452Z",
      "location_count": 4,
      "location_summary": "Atlanta, Georgia • New York, New York • Raleigh, North Carolina + 1 more",
      "locations": [
        {
          "city": "Atlanta",
          "state": "Georgia"
        },
        {
          "city": "New York",
          "state": "New York"
        },
        {
          "city": "Raleigh",
          "state": "North Carolina"
        },
        {
          "city": "Cincinnati",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03008447"
    },
    {
      "nct_id": "NCT00075296",
      "title": "FMRI Study of Performance During a Probabilistic Reversal Learning Task in Depression",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Major Depressive Disorder"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "National Institute of Mental Health (NIMH)",
      "sponsor_class": "NIH",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "50 Years",
        "sex": "ALL",
        "summary": "18 Years to 50 Years"
      },
      "enrollment_count": 100,
      "start_date": "2004-01-05",
      "completion_date": "2008-04-21",
      "has_results": false,
      "last_update_posted_date": "2017-07-02",
      "last_synced_at": "2026-05-22T08:13:35.452Z",
      "location_count": 1,
      "location_summary": "Bethesda, Maryland",
      "locations": [
        {
          "city": "Bethesda",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00075296"
    },
    {
      "nct_id": "NCT02265718",
      "title": "A Study To Evaluate The Difference In iPad-Based Cognitive Video Game (Akili Interactive's Project: EVO) Performance In Amyloid-Positive Versus Amyloid-Negative Healthy Elderly Volunteers",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Healthy"
      ],
      "interventions": [
        {
          "name": "Ritalin",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Pfizer",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "70 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "70 Years to 80 Years"
      },
      "enrollment_count": 97,
      "start_date": "2014-09",
      "completion_date": "2016-05",
      "has_results": false,
      "last_update_posted_date": "2019-06-05",
      "last_synced_at": "2026-05-22T08:13:35.452Z",
      "location_count": 4,
      "location_summary": "Long Beach, California • Hollywood, Florida • South Miami, Florida + 1 more",
      "locations": [
        {
          "city": "Long Beach",
          "state": "California"
        },
        {
          "city": "Hollywood",
          "state": "Florida"
        },
        {
          "city": "South Miami",
          "state": "Florida"
        },
        {
          "city": "Kalamazoo",
          "state": "Michigan"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02265718"
    },
    {
      "nct_id": "NCT07376564",
      "title": "Assessing the Impact of High Theacrine Doses on Hemodynamic Measures",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Hemodynamic Measure",
        "Cognitive Performance in Healthy Volunteers"
      ],
      "interventions": [
        {
          "name": "Maltodextrin (Placebo)",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Low dose theacrine",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Medium dose theacrine",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "High dose theacrine",
          "type": "DIETARY_SUPPLEMENT"
        }
      ],
      "intervention_types": [
        "DIETARY_SUPPLEMENT"
      ],
      "sponsor": "Titch Madzima",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "40 Years",
        "sex": "ALL",
        "summary": "18 Years to 40 Years"
      },
      "enrollment_count": 19,
      "start_date": "2023-08-09",
      "completion_date": "2024-11-01",
      "has_results": false,
      "last_update_posted_date": "2026-01-29",
      "last_synced_at": "2026-05-22T08:13:35.452Z",
      "location_count": 1,
      "location_summary": "Elon, North Carolina",
      "locations": [
        {
          "city": "Elon",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07376564"
    },
    {
      "nct_id": "NCT02353299",
      "title": "Assess the Effect of Zolpidem, Silenor & Placebo on Arousability, Ataxia/Balance & Cognition in Healthy Volunteers",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Healthy"
      ],
      "interventions": [
        {
          "name": "Silenor 6 mg",
          "type": "DRUG"
        },
        {
          "name": "zolpidem 10 mg",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Currax Pharmaceuticals",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "50 Years",
        "sex": "MALE",
        "summary": "21 Years to 50 Years · Male only"
      },
      "enrollment_count": 52,
      "start_date": "2015-01",
      "completion_date": "2016-03",
      "has_results": true,
      "last_update_posted_date": "2018-01-02",
      "last_synced_at": "2026-05-22T08:13:35.452Z",
      "location_count": 1,
      "location_summary": "Novi, Michigan",
      "locations": [
        {
          "city": "Novi",
          "state": "Michigan"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02353299"
    },
    {
      "nct_id": "NCT02518204",
      "title": "Validity of an Online Neurocognitive Test Battery, the Brain Performance Test (BPT), in Normal Healthy Adults",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Healthy Volunteers"
      ],
      "interventions": [
        {
          "name": "BPT",
          "type": "OTHER"
        },
        {
          "name": "NP",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Lumos Labs, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "70 Years",
        "maximum_age": "89 Years",
        "sex": "ALL",
        "summary": "70 Years to 89 Years"
      },
      "enrollment_count": 229,
      "start_date": "2015-07",
      "completion_date": "2017-02-28",
      "has_results": false,
      "last_update_posted_date": "2017-05-25",
      "last_synced_at": "2026-05-22T08:13:35.452Z",
      "location_count": 3,
      "location_summary": "Garden Grove, California • Oakland, California • Torrance, California",
      "locations": [
        {
          "city": "Garden Grove",
          "state": "California"
        },
        {
          "city": "Oakland",
          "state": "California"
        },
        {
          "city": "Torrance",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02518204"
    },
    {
      "nct_id": "NCT07225413",
      "title": "Short-Term Rhodiola Rosea for Anaerobic Performance and Cognitive Function in Resistance-Trained Adults",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Healthy Volunteers"
      ],
      "interventions": [
        {
          "name": "Rhodiola rosea (low dose)",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Rhodiola rosea (high dose)",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Placebo capsules",
          "type": "DIETARY_SUPPLEMENT"
        }
      ],
      "intervention_types": [
        "DIETARY_SUPPLEMENT"
      ],
      "sponsor": "Jacksonville State University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Weeks",
        "maximum_age": "40 Weeks",
        "sex": "ALL",
        "summary": "18 Weeks to 40 Weeks"
      },
      "enrollment_count": 27,
      "start_date": "2022-02-01",
      "completion_date": "2022-12-31",
      "has_results": false,
      "last_update_posted_date": "2025-11-06",
      "last_synced_at": "2026-05-22T08:13:35.452Z",
      "location_count": 1,
      "location_summary": "Jacksonville, Alabama",
      "locations": [
        {
          "city": "Jacksonville",
          "state": "Alabama"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07225413"
    },
    {
      "nct_id": "NCT02468856",
      "title": "Effect of Armodafinil on Simulated Driving",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Healthy Volunteers"
      ],
      "interventions": [
        {
          "name": "armodafinil",
          "type": "DRUG"
        },
        {
          "name": "Placebo (for armodafinil)",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of Florida",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "35 Years",
        "sex": "ALL",
        "summary": "18 Years to 35 Years"
      },
      "enrollment_count": 12,
      "start_date": "2017-05-21",
      "completion_date": "2017-11-30",
      "has_results": false,
      "last_update_posted_date": "2018-12-31",
      "last_synced_at": "2026-05-22T08:13:35.452Z",
      "location_count": 1,
      "location_summary": "Gainesville, Florida",
      "locations": [
        {
          "city": "Gainesville",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02468856"
    },
    {
      "nct_id": "NCT07089238",
      "title": "Evaluate the Effects of Citicoline on Mood in Healthy Adults",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Healthy"
      ],
      "interventions": [
        {
          "name": "Citicoline",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Placebo",
          "type": "DIETARY_SUPPLEMENT"
        }
      ],
      "intervention_types": [
        "DIETARY_SUPPLEMENT"
      ],
      "sponsor": "Kirin Holdings Company, Limited",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "21 Years to 65 Years"
      },
      "enrollment_count": 90,
      "start_date": "2025-07-31",
      "completion_date": "2026-03-31",
      "has_results": false,
      "last_update_posted_date": "2025-09-02",
      "last_synced_at": "2026-05-22T08:13:35.452Z",
      "location_count": 1,
      "location_summary": "Canfield, Ohio",
      "locations": [
        {
          "city": "Canfield",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07089238"
    },
    {
      "nct_id": "NCT02437097",
      "title": "The Effect of Aerobic Exercise and Gaming on Cognitive Performance",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Cognitive Performance in Healthy Volunteers"
      ],
      "interventions": [
        {
          "name": "Aerobic exercise",
          "type": "OTHER"
        },
        {
          "name": "Video Gaming",
          "type": "OTHER"
        },
        {
          "name": "Aerobic exercise and Video Gaming",
          "type": "OTHER"
        },
        {
          "name": "Control",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "New York Institute of Technology",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "30 Years",
        "sex": "ALL",
        "summary": "18 Years to 30 Years"
      },
      "enrollment_count": 40,
      "start_date": "2015-06",
      "completion_date": "2016-06",
      "has_results": false,
      "last_update_posted_date": "2016-07-12",
      "last_synced_at": "2026-05-22T08:13:35.452Z",
      "location_count": 1,
      "location_summary": "Old Westbury, New York",
      "locations": [
        {
          "city": "Old Westbury",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02437097"
    }
  ]
}