{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Cognitive+and+Executive+Dysfunction",
    "query": {
      "condition": "Cognitive and Executive Dysfunction"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 45,
    "total_pages": 5,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Cognitive+and+Executive+Dysfunction&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-09-06T07:34:11.054Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT07424365",
      "title": "Study to Investigate Vagus Nerve Stimulation to Augment Executive Function in Healthy and Cognitively Impaired Populations",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Mild Cognitive Impairment (MCI)",
        "Parkinsons Disease (PD)",
        "Healthy Adult"
      ],
      "interventions": [
        {
          "name": "transcutaneous auricular vagus nerve stimulation",
          "type": "DEVICE"
        },
        {
          "name": "sham stimulation",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "University of Colorado, Denver",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 80,
      "start_date": "2025-05-19",
      "completion_date": "2028-05",
      "has_results": false,
      "last_update_posted_date": "2026-02-20",
      "last_synced_at": "2026-09-06T07:34:11.054Z",
      "location_count": 1,
      "location_summary": "Aurora, Colorado",
      "locations": [
        {
          "city": "Aurora",
          "state": "Colorado"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07424365"
    },
    {
      "nct_id": "NCT01986777",
      "title": "LDX for the Treatment of Cognitive Functioning Issues in Women Post-Oophorectomy",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Cognitive Impairments",
        "RRSO"
      ],
      "interventions": [
        {
          "name": "lisdexamfetamine",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of Pennsylvania",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "30 Years",
        "maximum_age": "60 Years",
        "sex": "FEMALE",
        "summary": "30 Years to 60 Years · Female only"
      },
      "enrollment_count": 0,
      "start_date": "2013-07",
      "completion_date": "2013-12",
      "has_results": false,
      "last_update_posted_date": "2017-09-18",
      "last_synced_at": "2026-09-06T07:34:11.054Z",
      "location_count": 1,
      "location_summary": "Philadelphia, Pennsylvania",
      "locations": [
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01986777"
    },
    {
      "nct_id": "NCT05661084",
      "title": "Non-invasive Brain Stimulation for Cognitive and Motor Dysfunction in Dementia",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Dementia",
        "Memory Loss",
        "Alzheimer Disease",
        "Executive Dysfunction",
        "Mobility Limitation"
      ],
      "interventions": [
        {
          "name": "Transcranial alternating current stimulation (tACS) (active); Transcranial direct current stimulation (tDCS) (active)",
          "type": "DEVICE"
        },
        {
          "name": "Transcranial alternating current stimulation (tACS) (sham); Transcranial direct current stimulation (tDCS) (sham)",
          "type": "DEVICE"
        },
        {
          "name": "Transcranial alternating current stimulation (tACS) (active); Transcranial direct current stimulation (tDCS) (sham)",
          "type": "DEVICE"
        },
        {
          "name": "Transcranial alternating current stimulation (tACS) (sham); Transcranial direct current stimulation (tDCS) (active)",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Hebrew SeniorLife",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "55 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "55 Years and older"
      },
      "enrollment_count": 144,
      "start_date": "2023-01-24",
      "completion_date": "2027-08-31",
      "has_results": false,
      "last_update_posted_date": "2026-01-12",
      "last_synced_at": "2026-09-06T07:34:11.054Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05661084"
    },
    {
      "nct_id": "NCT03479606",
      "title": "Online Emotion Regulation Group Intervention",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Traumatic Brain Injury",
        "Executive Dysfunction",
        "Emotion Dysfunction",
        "Emotion Dysregulation"
      ],
      "interventions": [
        {
          "name": "Online Emotion Regulation Skills-training",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Icahn School of Medicine at Mount Sinai",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 137,
      "start_date": "2018-04-05",
      "completion_date": "2022-09-30",
      "has_results": false,
      "last_update_posted_date": "2022-10-06",
      "last_synced_at": "2026-09-06T07:34:11.054Z",
      "location_count": 1,
      "location_summary": "New York, New York",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03479606"
    },
    {
      "nct_id": "NCT03361293",
      "title": "Cognitive Training and tDCS for Children With FASD",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Fetal Alcohol Spectrum Disorders"
      ],
      "interventions": [
        {
          "name": "Active tDCS",
          "type": "DEVICE"
        },
        {
          "name": "Cognitive training",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Sham tDCS",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "BEHAVIORAL"
      ],
      "sponsor": "University of Minnesota",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "10 Years",
        "maximum_age": "16 Years",
        "sex": "ALL",
        "summary": "10 Years to 16 Years"
      },
      "enrollment_count": 44,
      "start_date": "2017-11-20",
      "completion_date": "2020-01-30",
      "has_results": true,
      "last_update_posted_date": "2021-03-17",
      "last_synced_at": "2026-09-06T07:34:11.054Z",
      "location_count": 1,
      "location_summary": "Minneapolis, Minnesota",
      "locations": [
        {
          "city": "Minneapolis",
          "state": "Minnesota"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03361293"
    },
    {
      "nct_id": "NCT05859126",
      "title": "Maternal Choline Supplementation and Offspring Cognition in Adolescence",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Cognitive Deficit in Attention",
        "Executive Dysfunction",
        "Emotional Regulation"
      ],
      "interventions": [
        {
          "name": "Maternal Choline Supplementation 930 mg/d",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Maternal Choline Supplementation 480 mg/d",
          "type": "DIETARY_SUPPLEMENT"
        }
      ],
      "intervention_types": [
        "DIETARY_SUPPLEMENT"
      ],
      "sponsor": "Cornell University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "13 Years",
        "maximum_age": "13 Years",
        "sex": "ALL",
        "summary": "13 Years to 13 Years"
      },
      "enrollment_count": 26,
      "start_date": "2023-06-23",
      "completion_date": "2024-12",
      "has_results": false,
      "last_update_posted_date": "2024-08-22",
      "last_synced_at": "2026-09-06T07:34:11.054Z",
      "location_count": 1,
      "location_summary": "Ithaca, New York",
      "locations": [
        {
          "city": "Ithaca",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05859126"
    },
    {
      "nct_id": "NCT03272555",
      "title": "WILD 5 Wellness: A 30-Day Intervention",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Wellness",
        "Anxiety",
        "Depression",
        "Cognitive and Executive Dysfunction"
      ],
      "interventions": [
        {
          "name": "WILD 5 Wellness Interventions",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Beloit College",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 14,
      "start_date": "2017-09-05",
      "completion_date": "2017-10-13",
      "has_results": false,
      "last_update_posted_date": "2018-04-26",
      "last_synced_at": "2026-09-06T07:34:11.054Z",
      "location_count": 1,
      "location_summary": "Beloit, Wisconsin",
      "locations": [
        {
          "city": "Beloit",
          "state": "Wisconsin"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03272555"
    },
    {
      "nct_id": "NCT05655325",
      "title": "Accelerated Age-related Cognitive Decline: Impact of Exercise on Executive Function and Neuroplasticity",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Mild Cognitive Impairment",
        "Chronic Kidney Diseases"
      ],
      "interventions": [
        {
          "name": "Home-based walking exercise",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Attention control",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL",
        "OTHER"
      ],
      "sponsor": "Columbia University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "55 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "55 Years and older"
      },
      "enrollment_count": 144,
      "start_date": "2024-06-18",
      "completion_date": "2027-02-01",
      "has_results": false,
      "last_update_posted_date": "2026-04-13",
      "last_synced_at": "2026-09-06T07:34:11.054Z",
      "location_count": 1,
      "location_summary": "New York, New York",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05655325"
    },
    {
      "nct_id": "NCT07226219",
      "title": "Methylphenidate to Address Attention and Executive Deficits Among Children With Sickle Cell Disease",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Sickle Cell Disease",
        "Executive Dysfunction",
        "Cognitive Impairment",
        "Attention Deficit/Hyperactivity Disorder (ADHD)"
      ],
      "interventions": [
        {
          "name": "Extended-Release Methylphenidate",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "St. Jude Children's Research Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "8 Years",
        "maximum_age": "17 Years",
        "sex": "ALL",
        "summary": "8 Years to 17 Years"
      },
      "enrollment_count": 72,
      "start_date": "2025-11-25",
      "completion_date": "2028-08-01",
      "has_results": false,
      "last_update_posted_date": "2026-07-06",
      "last_synced_at": "2026-09-06T07:34:11.054Z",
      "location_count": 1,
      "location_summary": "Memphis, Tennessee",
      "locations": [
        {
          "city": "Memphis",
          "state": "Tennessee"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07226219"
    },
    {
      "nct_id": "NCT07097051",
      "title": "Multi-session Transcranial Alternating Current Stimulation to Improve Dual-task Standing and Brain Activity in Older Adults With Mild Cognitive Impairment",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Mild Cognitive Impairment (MCI)"
      ],
      "interventions": [
        {
          "name": "real tACS",
          "type": "OTHER"
        },
        {
          "name": "sham tACS",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "High Point University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "65 Years",
        "maximum_age": "85 Years",
        "sex": "ALL",
        "summary": "65 Years to 85 Years"
      },
      "enrollment_count": 20,
      "start_date": "2025-05-13",
      "completion_date": "2026-12-31",
      "has_results": false,
      "last_update_posted_date": "2025-07-31",
      "last_synced_at": "2026-09-06T07:34:11.054Z",
      "location_count": 1,
      "location_summary": "High Point, North Carolina",
      "locations": [
        {
          "city": "High Point",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07097051"
    }
  ]
}