{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Cognitively+Normal+Older+Adults",
    "query": {
      "condition": "Cognitively Normal Older Adults"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 13,
    "total_pages": 2,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Cognitively+Normal+Older+Adults&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-06-11T01:22:03.211Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT01962779",
      "title": "Sleep, Aging and Risk for Alzheimer's Disease",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Sleep Disordered Breathing",
        "Alzheimer's Disease"
      ],
      "interventions": [
        {
          "name": "Continuous positive airway pressure (CPAP)",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "NYU Langone Health",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "50 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "50 Years and older"
      },
      "enrollment_count": 235,
      "start_date": "2013-07-31",
      "completion_date": "2017-05-03",
      "has_results": false,
      "last_update_posted_date": "2020-07-21",
      "last_synced_at": "2026-06-11T01:22:03.211Z",
      "location_count": 2,
      "location_summary": "New York, New York",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        },
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01962779"
    },
    {
      "nct_id": "NCT03053908",
      "title": "Orexin and Tau Pathology in Cognitively Normal Elderly",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Elderly",
        "Alzheimer Disease"
      ],
      "interventions": [
        {
          "name": "Actigraphy",
          "type": "PROCEDURE"
        },
        {
          "name": "Nocturnal Polysomnograpahy (NPSG)",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "NYU Langone Health",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "55 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "55 Years to 75 Years"
      },
      "enrollment_count": 25,
      "start_date": "2018-03-27",
      "completion_date": "2019-05-13",
      "has_results": false,
      "last_update_posted_date": "2021-02-24",
      "last_synced_at": "2026-06-11T01:22:03.211Z",
      "location_count": 1,
      "location_summary": "New York, New York",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03053908"
    },
    {
      "nct_id": "NCT01729598",
      "title": "Valproic Acid in Subjects With Intact Cognition - Proof of Concept Study",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "EARLY_PHASE1"
      ],
      "conditions": [
        "Alzheimer's Disease"
      ],
      "interventions": [
        {
          "name": "Valproic Acid",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Gregory Jicha, 323-5550",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "65 Years",
        "maximum_age": "90 Years",
        "sex": "ALL",
        "summary": "65 Years to 90 Years"
      },
      "enrollment_count": 14,
      "start_date": "2012-04",
      "completion_date": "2014-10",
      "has_results": true,
      "last_update_posted_date": "2019-10-09",
      "last_synced_at": "2026-06-11T01:22:03.211Z",
      "location_count": 1,
      "location_summary": "Lexington, Kentucky",
      "locations": [
        {
          "city": "Lexington",
          "state": "Kentucky"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01729598"
    },
    {
      "nct_id": "NCT01222351",
      "title": "Measuring Brain Amyloid Plaque Load in Older Adults Using BAY 94-9172",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Late Onset Alzheimer Disease"
      ],
      "interventions": [
        {
          "name": "BAY 94-9172 (Florbetaben)",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "New York State Psychiatric Institute",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "65 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "65 Years and older"
      },
      "enrollment_count": 161,
      "start_date": "2010-12",
      "completion_date": "2014-10-22",
      "has_results": true,
      "last_update_posted_date": "2024-05-06",
      "last_synced_at": "2026-06-11T01:22:03.211Z",
      "location_count": 1,
      "location_summary": "New York, New York",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01222351"
    },
    {
      "nct_id": "NCT03814603",
      "title": "The Sleep Amyloid, Slow WAve Race and Ethnicity Study",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Alzheimer Disease"
      ],
      "interventions": [
        {
          "name": "PET-MR Scan",
          "type": "PROCEDURE"
        },
        {
          "name": "PiB",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "PROCEDURE",
        "DRUG"
      ],
      "sponsor": "NYU Langone Health",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "60 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "60 Years to 75 Years"
      },
      "enrollment_count": 210,
      "start_date": "2018-11-21",
      "completion_date": "2025-05-31",
      "has_results": false,
      "last_update_posted_date": "2025-09-22",
      "last_synced_at": "2026-06-11T01:22:03.211Z",
      "location_count": 1,
      "location_summary": "New York, New York",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03814603"
    },
    {
      "nct_id": "NCT05331144",
      "title": "Impact of Intensive Treatment of SBP on Brain Perfusion, Amyloid, and Tau (IPAT Study)",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Cognitively Normal Older Adults",
        "Hypertension",
        "Subjective Cognitive Decline",
        "Family History of Dementia"
      ],
      "interventions": [
        {
          "name": "Angiotensin II Receptor Blockers (ARBs, losartan) and Calcium Channel Blockers (CCB, amlodipine)",
          "type": "DRUG"
        },
        {
          "name": "PCP",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DRUG",
        "OTHER"
      ],
      "sponsor": "Rong Zhang",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "60 Years",
        "maximum_age": "85 Years",
        "sex": "ALL",
        "summary": "60 Years to 85 Years"
      },
      "enrollment_count": 180,
      "start_date": "2022-10-25",
      "completion_date": "2027-12-31",
      "has_results": false,
      "last_update_posted_date": "2025-08-05",
      "last_synced_at": "2026-06-11T01:22:03.211Z",
      "location_count": 1,
      "location_summary": "Dallas, Texas",
      "locations": [
        {
          "city": "Dallas",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05331144"
    },
    {
      "nct_id": "NCT00855868",
      "title": "Ability Of ([18F]-AV-45) PET Scan to Distinguish Alzheimer's Disease Subjects From Cognitively Normal Individuals",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Alzheimer's Disease"
      ],
      "interventions": [
        {
          "name": "florbetapir F 18",
          "type": "DRUG"
        },
        {
          "name": "[11C]-PIB",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Avid Radiopharmaceuticals",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "55 Years",
        "maximum_age": "90 Years",
        "sex": "ALL",
        "summary": "55 Years to 90 Years"
      },
      "enrollment_count": 28,
      "start_date": "2009-03",
      "completion_date": "2011-01",
      "has_results": true,
      "last_update_posted_date": "2012-07-26",
      "last_synced_at": "2026-06-11T01:22:03.211Z",
      "location_count": 1,
      "location_summary": "Philadelphia, Pennsylvania",
      "locations": [
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00855868"
    },
    {
      "nct_id": "NCT06364189",
      "title": "Inspiring Seniors Toward Exercise Promotion",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Cognitively Normal Older Adults"
      ],
      "interventions": [
        {
          "name": "Music",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Exercise",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of North Carolina, Greensboro",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "65 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "65 Years and older"
      },
      "enrollment_count": 54,
      "start_date": "2024-05-15",
      "completion_date": "2025-08-31",
      "has_results": false,
      "last_update_posted_date": "2025-12-08",
      "last_synced_at": "2026-06-11T01:22:03.211Z",
      "location_count": 2,
      "location_summary": "Atlanta, Georgia • Greensboro, North Carolina",
      "locations": [
        {
          "city": "Atlanta",
          "state": "Georgia"
        },
        {
          "city": "Greensboro",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06364189"
    },
    {
      "nct_id": "NCT02913664",
      "title": "Risk Reduction for Alzheimer's Disease",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2",
        "PHASE3"
      ],
      "conditions": [
        "Cognitively Normal Older Adults",
        "Hypertension",
        "Subjective Cognitive Decline",
        "Family History of Alzheimer's Disease"
      ],
      "interventions": [
        {
          "name": "Angiotensin II receptor blocker (ARB, losartan) and calcium channel blocker (CCB, amlodipine)",
          "type": "DRUG"
        },
        {
          "name": "Aerobic Exercise Training",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Usual Care",
          "type": "OTHER"
        },
        {
          "name": "Stretching Exercise",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "DRUG",
        "BEHAVIORAL",
        "OTHER"
      ],
      "sponsor": "University of Texas Southwestern Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "60 Years",
        "maximum_age": "85 Years",
        "sex": "ALL",
        "summary": "60 Years to 85 Years"
      },
      "enrollment_count": 513,
      "start_date": "2017-02-02",
      "completion_date": "2022-01-31",
      "has_results": false,
      "last_update_posted_date": "2022-02-15",
      "last_synced_at": "2026-06-11T01:22:03.211Z",
      "location_count": 4,
      "location_summary": "Kansas City, Kansas • Baton Rouge, Louisiana • St Louis, Missouri + 1 more",
      "locations": [
        {
          "city": "Kansas City",
          "state": "Kansas"
        },
        {
          "city": "Baton Rouge",
          "state": "Louisiana"
        },
        {
          "city": "St Louis",
          "state": "Missouri"
        },
        {
          "city": "Dallas",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02913664"
    },
    {
      "nct_id": "NCT04421014",
      "title": "Ketone Ester Effects on Biomarkers of Brain Metabolism and Cognitive Performance in Cognitively Intact Adults 55 Years Old or Older",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Metabolic Syndrome",
        "Normal Cognition"
      ],
      "interventions": [
        {
          "name": "Ketone Ester drink",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Placebo: isocaloric dextrose drink",
          "type": "DIETARY_SUPPLEMENT"
        }
      ],
      "intervention_types": [
        "DIETARY_SUPPLEMENT"
      ],
      "sponsor": "National Institute on Aging (NIA)",
      "sponsor_class": "NIH",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "55 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "55 Years and older"
      },
      "enrollment_count": 99,
      "start_date": "2021-06-24",
      "completion_date": "2025-06-02",
      "has_results": true,
      "last_update_posted_date": "2026-04-02",
      "last_synced_at": "2026-06-11T01:22:03.211Z",
      "location_count": 1,
      "location_summary": "Baltimore, Maryland",
      "locations": [
        {
          "city": "Baltimore",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04421014"
    }
  ]
}