{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Colorectal+Cancer&page=50", "query": { "condition": "Colorectal Cancer", "page": 50 }, "page_size": 10 }, "pagination": { "page": 50, "page_size": 10, "total_count": 3453, "total_pages": 346, "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Colorectal+Cancer&page=51&page_size=10", "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Colorectal+Cancer&page=49&page_size=10" }, "source": "remote", "last_synced_at": "2026-11-04T04:18:44.789Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT00940316", "title": "Dual Epidermal Growth Factor Receptor Inhibition With Erlotinib and Panitumumab With or Without Chemotherapy for Advanced Colorectal Cancer", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Colorectal Cancer" ], "interventions": [ { "name": "panitumumab", "type": "BIOLOGICAL" }, { "name": "erlotinib hydrochloride", "type": "DRUG" }, { "name": "irinotecan hydrochloride", "type": "DRUG" } ], "intervention_types": [ "BIOLOGICAL", "DRUG" ], "sponsor": "Northwestern University", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 28, "start_date": "2010-01-18", "completion_date": "2015-01", "has_results": true, "last_update_posted_date": "2019-05-07", "last_synced_at": "2026-11-04T04:18:44.789Z", "location_count": 10, "location_summary": "Arlington Heights, Illinois • Chicago, Illinois • Joliet, Illinois + 6 more", "locations": [ { "city": "Arlington Heights", "state": "Illinois" }, { "city": "Chicago", "state": "Illinois" }, { "city": "Chicago", "state": "Illinois" }, { "city": "Joliet", "state": "Illinois" }, { "city": "Terre Haute", "state": "Indiana" } ], "official_url": "https://clinicaltrials.gov/study/NCT00940316" }, { "nct_id": "NCT01515787", "title": "PROSPECT: Chemotherapy Alone or Chemotherapy Plus Radiation Therapy in Treating Patients With Locally Advanced Rectal Cancer Undergoing Surgery", "overall_status": "UNKNOWN", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2", "PHASE3" ], "conditions": [ "Colorectal Cancer" ], "interventions": [ { "name": "FOLFOX (chemotherapy)", "type": "DRUG" }, { "name": "5 FUCMT (chemoradiation)", "type": "OTHER" }, { "name": "surgery", "type": "PROCEDURE" }, { "name": "magnetic resonance imaging or endorectal ultrasound", "type": "PROCEDURE" } ], "intervention_types": [ "DRUG", "OTHER", "PROCEDURE" ], "sponsor": "Alliance for Clinical Trials in Oncology", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 1194, "start_date": "2012-06-12", "completion_date": "2024-06-30", "has_results": true, "last_update_posted_date": "2024-02-02", "last_synced_at": "2026-11-04T04:18:44.789Z", "location_count": 1048, "location_summary": "Birmingham, Alabama • Daphne, Alabama • Mobile, Alabama + 613 more", "locations": [ { "city": "Birmingham", "state": "Alabama" }, { "city": "Daphne", "state": "Alabama" }, { "city": "Mobile", "state": "Alabama" }, { "city": "Mobile", "state": "Alabama" }, { "city": "Mobile", "state": "Alabama" } ], "official_url": "https://clinicaltrials.gov/study/NCT01515787" }, { "nct_id": "NCT01586416", "title": "Intervention to Increase Chemotherapy Tolerance in Elderly Cancer Patients", "overall_status": "UNKNOWN", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Colonic Neoplasms" ], "interventions": [ { "name": "Behavioral Intervention", "type": "BEHAVIORAL" } ], "intervention_types": [ "BEHAVIORAL" ], "sponsor": "Massachusetts General Hospital", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "60 Years", "maximum_age": null, "sex": "ALL", "summary": "60 Years and older" }, "enrollment_count": 15, "start_date": "2012-12", "completion_date": "2020-12", "has_results": false, "last_update_posted_date": "2020-09-02", "last_synced_at": "2026-11-04T04:18:44.789Z", "location_count": 1, "location_summary": "Boston, Massachusetts", "locations": [ { "city": "Boston", "state": "Massachusetts" } ], "official_url": "https://clinicaltrials.gov/study/NCT01586416" }, { "nct_id": "NCT02002689", "title": "LDE225 for Patients With PTCH1 or SMO Mutated Tumors", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "PTCH1 or SMO Activated Solid and Hematologic Tumors" ], "interventions": [ { "name": "LDE225", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Novartis Pharmaceuticals", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 10, "start_date": "2014-02", "completion_date": "2015-03", "has_results": true, "last_update_posted_date": "2016-05-02", "last_synced_at": "2026-11-04T04:18:44.789Z", "location_count": 10, "location_summary": "Sacramento, California • Greenwood Village, Colorado • Chicago, Illinois + 6 more", "locations": [ { "city": "Sacramento", "state": "California" }, { "city": "Greenwood Village", "state": "Colorado" }, { "city": "Chicago", "state": "Illinois" }, { "city": "Minneapolis", "state": "Minnesota" }, { "city": "Cleveland", "state": "Ohio" } ], "official_url": "https://clinicaltrials.gov/study/NCT02002689" }, { "nct_id": "NCT00165568", "title": "Using Positron Emission Tomography to Evaluate the Effects of Bevacizumab on Intra-tumoral Pharmacokinetics of 5-fluorouracil in Metastatic Colorectal Cancer", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Colorectal Cancer", "Neoplasm Metastasis" ], "interventions": [ { "name": "Bevacizumab", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Dana-Farber Cancer Institute", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 20, "start_date": "2005-07", "completion_date": "2006-10", "has_results": false, "last_update_posted_date": "2009-11-02", "last_synced_at": "2026-11-04T04:18:44.789Z", "location_count": 2, "location_summary": "Boston, Massachusetts", "locations": [ { "city": "Boston", "state": "Massachusetts" }, { "city": "Boston", "state": "Massachusetts" } ], "official_url": "https://clinicaltrials.gov/study/NCT00165568" }, { "nct_id": "NCT07503808", "title": "A Study of IDE034 in Adult Participants With Locally Advanced/Metastatic Solid Tumors Types", "overall_status": "RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "Esophageal Squamous Cell Carcinoma", "High Grade Serous Ovarian Cancer", "Head and Neck Squamous Cell Carcinoma", "Colorectal Cancer", "Castration-resistant Prostate Cancer", "Non Small Cell Lung Cancer", "Endometrium Cancer", "Triple Negative Breast Cancer" ], "interventions": [ { "name": "IDE034", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "IDEAYA Biosciences", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 150, "start_date": "2026-02-24", "completion_date": "2027-07-30", "has_results": false, "last_update_posted_date": "2026-06-18", "last_synced_at": "2026-11-04T04:18:44.789Z", "location_count": 15, "location_summary": "Denver, Colorado • Sarasota, Florida • Detroit, Michigan + 10 more", "locations": [ { "city": "Denver", "state": "Colorado" }, { "city": "Sarasota", "state": "Florida" }, { "city": "Detroit", "state": "Michigan" }, { "city": "Lake Success", "state": "New York" }, { "city": "Nashville", "state": "Tennessee" } ], "official_url": "https://clinicaltrials.gov/study/NCT07503808" }, { "nct_id": "NCT07318389", "title": "ASCEND-CRC: Profiling and Targeting Dynamic Tumor Resistance in Patients With Metastatic Colorectal Cancer", "overall_status": "RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "EARLY_PHASE1" ], "conditions": [ "Dynamic Tumor Resistance", "Metastatic Colorectal Cancer" ], "interventions": [ { "name": "SOC (Standard of care)", "type": "OTHER" }, { "name": "Bevacizumab", "type": "DRUG" }, { "name": "Cetuximab", "type": "DRUG" }, { "name": "Panitumumab", "type": "DRUG" }, { "name": "FOLFIRI", "type": "DRUG" }, { "name": "FOLFOX", "type": "DRUG" }, { "name": "Encorafenib", "type": "DRUG" }, { "name": "Adagrasib", "type": "DRUG" }, { "name": "Trifluridine/tipiracil (TAS-102)", "type": "DRUG" }, { "name": "Trastuzumab deruxtecan", "type": "DRUG" }, { "name": "Tucatinib", "type": "DRUG" }, { "name": "Sotorasib", "type": "DRUG" } ], "intervention_types": [ "OTHER", "DRUG" ], "sponsor": "M.D. Anderson Cancer Center", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 100, "start_date": "2026-04-22", "completion_date": "2029-11-14", "has_results": false, "last_update_posted_date": "2026-10-14", "last_synced_at": "2026-11-04T04:18:44.789Z", "location_count": 1, "location_summary": "Houston, Texas", "locations": [ { "city": "Houston", "state": "Texas" } ], "official_url": "https://clinicaltrials.gov/study/NCT07318389" }, { "nct_id": "NCT00436072", "title": "ZD6474, Cetuximab, and Irinotecan in Patients With Metastatic Colorectal Cancer", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "Colorectal Cancer" ], "interventions": [ { "name": "ZD6474", "type": "DRUG" }, { "name": "Cetuximab", "type": "DRUG" }, { "name": "Irinotecan", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Dana-Farber Cancer Institute", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 46, "start_date": "2007-02", "completion_date": "2012-08", "has_results": false, "last_update_posted_date": "2012-10-04", "last_synced_at": "2026-11-04T04:18:44.789Z", "location_count": 3, "location_summary": "Boston, Massachusetts", "locations": [ { "city": "Boston", "state": "Massachusetts" }, { "city": "Boston", "state": "Massachusetts" }, { "city": "Boston", "state": "Massachusetts" } ], "official_url": "https://clinicaltrials.gov/study/NCT00436072" }, { "nct_id": "NCT01164215", "title": "Biomarker-Guided Fluorouracil in Treating Patients With Colorectal Cancer Receiving Combination Chemotherapy", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "Colorectal Cancer", "Diarrhea", "Neutropenia" ], "interventions": [ { "name": "fluorouracil", "type": "DRUG" }, { "name": "leucovorin", "type": "DRUG" }, { "name": "oxaliplatin", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "UNC Lineberger Comprehensive Cancer Center", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": null, "maximum_age": null, "sex": "ALL", "summary": "Not listed" }, "enrollment_count": 76, "start_date": "2010-02", "completion_date": "2013-09", "has_results": false, "last_update_posted_date": "2015-10-09", "last_synced_at": "2026-11-04T04:18:44.789Z", "location_count": 5, "location_summary": "Asheville, North Carolina • Greensboro, North Carolina • Greenville, North Carolina + 2 more", "locations": [ { "city": "Asheville", "state": "North Carolina" }, { "city": "Greensboro", "state": "North Carolina" }, { "city": "Greenville", "state": "North Carolina" }, { "city": "Raleigh", "state": "North Carolina" }, { "city": "Washington", "state": "North Carolina" } ], "official_url": "https://clinicaltrials.gov/study/NCT01164215" }, { "nct_id": "NCT05688280", "title": "Intratumoral Injection of IP-001 Following Thermal Ablation in Patients With CRC, NSCLC, and STS", "overall_status": "ACTIVE_NOT_RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1", "PHASE2" ], "conditions": [ "Metastatic Solid Tumor", "Colon Cancer", "Nonsmall Cell Lung Cancer", "Soft Tissue Sarcoma" ], "interventions": [ { "name": "1.0% IP-001 for Injection", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Immunophotonics, Inc.", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 42, "start_date": "2022-11-29", "completion_date": "2025-02", "has_results": false, "last_update_posted_date": "2025-01-08", "last_synced_at": "2026-11-04T04:18:44.789Z", "location_count": 3, "location_summary": "Coral Gables, Florida • Louisville, Kentucky • Oklahoma City, Oklahoma", "locations": [ { "city": "Coral Gables", "state": "Florida" }, { "city": "Louisville", "state": "Kentucky" }, { "city": "Oklahoma City", "state": "Oklahoma" } ], "official_url": "https://clinicaltrials.gov/study/NCT05688280" } ] }