{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Congenital+Heart+Defects&page=2",
    "query": {
      "condition": "Congenital Heart Defects",
      "page": 2
    },
    "page_size": 10
  },
  "pagination": {
    "page": 2,
    "page_size": 10,
    "total_count": 10,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Congenital+Heart+Defects&page=1&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-05-22T09:46:44.391Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT00001253",
      "title": "The Effects of Estrogen on Cognition in Girls With Turner Syndrome",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Gonadal Dysgenesis",
        "Turner's Syndrome"
      ],
      "interventions": [
        {
          "name": "cognitive tests and scales",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)",
      "sponsor_class": "NIH",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 950,
      "start_date": "1990-05",
      "completion_date": "2004-03",
      "has_results": false,
      "last_update_posted_date": "2008-03-04",
      "last_synced_at": "2026-05-22T09:46:44.391Z",
      "location_count": 1,
      "location_summary": "Bethesda, Maryland",
      "locations": [
        {
          "city": "Bethesda",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00001253"
    },
    {
      "nct_id": "NCT03023644",
      "title": "Improving Neurodevelopmental Outcomes in Children With Congenital Heart Disease: An Intervention Study",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Congenital Heart Defect",
        "Executive Function",
        "Children",
        "Neurodevelopmental Disorders",
        "Working Memory",
        "Infant Open Heart Surgery"
      ],
      "interventions": [
        {
          "name": "Cogmed Working Memory Training",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Boston Children's Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "7 Years",
        "maximum_age": "12 Years",
        "sex": "ALL",
        "summary": "7 Years to 12 Years"
      },
      "enrollment_count": 106,
      "start_date": "2017-02-21",
      "completion_date": "2020-09-30",
      "has_results": false,
      "last_update_posted_date": "2021-02-01",
      "last_synced_at": "2026-05-22T09:46:44.391Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03023644"
    },
    {
      "nct_id": "NCT01639937",
      "title": "Myocardial Perfusion and Scarring in Congenital Heart Disease",
      "overall_status": "TERMINATED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Congenital Heart Disease"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "National Heart, Lung, and Blood Institute (NHLBI)",
      "sponsor_class": "NIH",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "18 Years to 80 Years"
      },
      "enrollment_count": 18,
      "start_date": "2012-10-24",
      "completion_date": "2019-12-12",
      "has_results": false,
      "last_update_posted_date": "2021-12-02",
      "last_synced_at": "2026-05-22T09:46:44.391Z",
      "location_count": 3,
      "location_summary": "Washington D.C., District of Columbia • Bethesda, Maryland",
      "locations": [
        {
          "city": "Washington D.C.",
          "state": "District of Columbia"
        },
        {
          "city": "Bethesda",
          "state": "Maryland"
        },
        {
          "city": "Bethesda",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01639937"
    },
    {
      "nct_id": "NCT02043379",
      "title": "Post-bypass Prophylactic IVIG in Infants and Neonates",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Hypogammaglobulinemia",
        "Congenital Heart Disease"
      ],
      "interventions": [
        {
          "name": "IVIG",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DRUG",
        "OTHER"
      ],
      "sponsor": "University of Alabama at Birmingham",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": "6 Months",
        "sex": "ALL",
        "summary": "Up to 6 Months"
      },
      "enrollment_count": 50,
      "start_date": "2014-05",
      "completion_date": "2015-06",
      "has_results": true,
      "last_update_posted_date": "2017-04-13",
      "last_synced_at": "2026-05-22T09:46:44.391Z",
      "location_count": 1,
      "location_summary": "Birmingham, Alabama",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02043379"
    },
    {
      "nct_id": "NCT00001460",
      "title": "Evaluation and Treatment of Heart Disease in Patients Not Participating in Research",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Arrhythmia",
        "Congenital Heart Defect",
        "Heart Disease"
      ],
      "interventions": [
        {
          "name": "inpatient evaluation and management",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "National Heart, Lung, and Blood Institute (NHLBI)",
      "sponsor_class": "NIH",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": null,
      "start_date": "1995-01",
      "completion_date": "2002-04",
      "has_results": false,
      "last_update_posted_date": "2008-03-05",
      "last_synced_at": "2026-05-22T09:46:44.391Z",
      "location_count": 1,
      "location_summary": "Bethesda, Maryland",
      "locations": [
        {
          "city": "Bethesda",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00001460"
    },
    {
      "nct_id": "NCT01484886",
      "title": "Restrictive Versus Liberal Transfusion Protocol in Infants Undergoing Cardiac Surgery",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Impaired Oxygen Delivery",
        "Congenital Heart Disease"
      ],
      "interventions": [
        {
          "name": "Red blood cell transfusion",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of Rochester",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": "7 Months",
        "sex": "ALL",
        "summary": "Up to 7 Months"
      },
      "enrollment_count": 162,
      "start_date": "2012-01",
      "completion_date": "2014-09",
      "has_results": false,
      "last_update_posted_date": "2014-09-05",
      "last_synced_at": "2026-05-22T09:46:44.391Z",
      "location_count": 1,
      "location_summary": "Rochester, New York",
      "locations": [
        {
          "city": "Rochester",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01484886"
    },
    {
      "nct_id": "NCT01068366",
      "title": "Nickel Allergy With Septal Closure Devices",
      "overall_status": "TERMINATED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Atrial Septal Defect",
        "Patent Foramen Ovale",
        "Allergic Reaction to Nickel"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "University of Utah",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 4,
      "start_date": "2010-02",
      "completion_date": "2010-11",
      "has_results": false,
      "last_update_posted_date": "2013-05-15",
      "last_synced_at": "2026-05-22T09:46:44.391Z",
      "location_count": 1,
      "location_summary": "Salt Lake City, Utah",
      "locations": [
        {
          "city": "Salt Lake City",
          "state": "Utah"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01068366"
    },
    {
      "nct_id": "NCT01656993",
      "title": "Antiplatelet Activity of Aspirin in Infants After Aortopulmonary and Cavopulmonary Shunts",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Congenital Heart Disease"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "University of Utah",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "2 Days",
        "maximum_age": "12 Months",
        "sex": "ALL",
        "summary": "2 Days to 12 Months"
      },
      "enrollment_count": 25,
      "start_date": "2012-11",
      "completion_date": "2014-12",
      "has_results": false,
      "last_update_posted_date": "2017-05-05",
      "last_synced_at": "2026-05-22T09:46:44.391Z",
      "location_count": 1,
      "location_summary": "Salt Lake City, Utah",
      "locations": [
        {
          "city": "Salt Lake City",
          "state": "Utah"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01656993"
    },
    {
      "nct_id": "NCT01903564",
      "title": "Fetal and Neonatal Magnetophysiology",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Fetal Arrhythmia",
        "Abnormality in Fetal Heart Rate or Rhythm",
        "Long QT Syndrome"
      ],
      "interventions": [
        {
          "name": "magnetocardiography",
          "type": "DEVICE"
        },
        {
          "name": "postnatal ECG",
          "type": "DEVICE"
        },
        {
          "name": "fetal echocardiography",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "University of Wisconsin, Madison",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "60 Years",
        "sex": "FEMALE",
        "summary": "18 Years to 60 Years · Female only"
      },
      "enrollment_count": 39,
      "start_date": "2014-03",
      "completion_date": "2018-06",
      "has_results": true,
      "last_update_posted_date": "2019-05-29",
      "last_synced_at": "2026-05-22T09:46:44.391Z",
      "location_count": 1,
      "location_summary": "Madison, Wisconsin",
      "locations": [
        {
          "city": "Madison",
          "state": "Wisconsin"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01903564"
    },
    {
      "nct_id": "NCT04956952",
      "title": "Enhanced External Counterpulsation in Patients With Fontan Circulation",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Single-ventricle",
        "Congenital Heart Disease"
      ],
      "interventions": [
        {
          "name": "EECP",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Boston Children's Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 23,
      "start_date": "2022-03-31",
      "completion_date": "2023-05-17",
      "has_results": false,
      "last_update_posted_date": "2023-06-13",
      "last_synced_at": "2026-05-22T09:46:44.391Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04956952"
    }
  ]
}