{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Connective+Tissue+Disease-Associated+Pulmonary+Arterial+Hypertension", "query": { "condition": "Connective Tissue Disease-Associated Pulmonary Arterial Hypertension" }, "page_size": 10 }, "pagination": { "page": 1, "page_size": 10, "total_count": 18, "total_pages": 2, "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Connective+Tissue+Disease-Associated+Pulmonary+Arterial+Hypertension&page=2&page_size=10", "previous_page_url": null }, "source": "remote", "last_synced_at": "2026-10-13T06:14:41.246Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT01086540", "title": "Rituximab for Treatment of Systemic Sclerosis-Associated Pulmonary Arterial Hypertension (SSc-PAH)", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Systemic Sclerosis-Associated PAH" ], "interventions": [ { "name": "Rituximab", "type": "BIOLOGICAL" }, { "name": "Placebo", "type": "OTHER" }, { "name": "CMRI", "type": "DIAGNOSTIC_TEST" }, { "name": "prednisone", "type": "DRUG" }, { "name": "methylprednisolone", "type": "DRUG" }, { "name": "diphenhydramine", "type": "DRUG" }, { "name": "acetaminophen", "type": "DRUG" } ], "intervention_types": [ "BIOLOGICAL", "OTHER", "DIAGNOSTIC_TEST", "DRUG" ], "sponsor": "National Institute of Allergy and Infectious Diseases (NIAID)", "sponsor_class": "NIH", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "75 Years", "sex": "ALL", "summary": "18 Years to 75 Years" }, "enrollment_count": 57, "start_date": "2011-06-24", "completion_date": "2019-12-15", "has_results": true, "last_update_posted_date": "2023-02-21", "last_synced_at": "2026-10-13T06:14:41.246Z", "location_count": 17, "location_summary": "Stanford, California • Aurora, Colorado • Iowa City, Iowa + 13 more", "locations": [ { "city": "Stanford", "state": "California" }, { "city": "Aurora", "state": "Colorado" }, { "city": "Iowa City", "state": "Iowa" }, { "city": "Baltimore", "state": "Maryland" }, { "city": "Boston", "state": "Massachusetts" } ], "official_url": "https://clinicaltrials.gov/study/NCT01086540" }, { "nct_id": "NCT00323024", "title": "Dose Determination Safety and Activity Study of Inhaled NX1011 to Treat Pulmonary Arterial Hypertension", "overall_status": "WITHDRAWN", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Pulmonary Hypertension" ], "interventions": [ { "name": "NX1011", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "NITROX, LLC", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "75 Years", "sex": "ALL", "summary": "18 Years to 75 Years" }, "enrollment_count": 72, "start_date": "2006-09", "completion_date": "2007-05", "has_results": false, "last_update_posted_date": "2007-08-30", "last_synced_at": "2026-10-13T06:14:41.246Z", "location_count": 6, "location_summary": "Phoenix, Arizona • La Jolla, California • Newark, Delaware + 3 more", "locations": [ { "city": "Phoenix", "state": "Arizona" }, { "city": "La Jolla", "state": "California" }, { "city": "Newark", "state": "Delaware" }, { "city": "Baltimore", "state": "Maryland" }, { "city": "Boston", "state": "Massachusetts" } ], "official_url": "https://clinicaltrials.gov/study/NCT00323024" }, { "nct_id": "NCT03626688", "title": "A Study Evaluating the Efficacy and Safety of Ralinepag to Improve Treatment Outcomes in PAH Patients", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "PAH", "Pulmonary Hypertension", "Pulmonary Arterial Hypertension", "Hypertension", "Connective Tissue Diseases", "Familial Primary Pulmonary Hypertension", "Vascular Diseases", "Cardiovascular Diseases", "Hypertension, Pulmonary", "Lung Diseases", "Respiratory Tract Disease" ], "interventions": [ { "name": "Ralinepag", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "United Therapeutics", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 687, "start_date": "2019-01-24", "completion_date": "2025-12-31", "has_results": false, "last_update_posted_date": "2026-06-16", "last_synced_at": "2026-10-13T06:14:41.246Z", "location_count": 68, "location_summary": "Birmingham, Alabama • Phoenix, Arizona • Tucson, Arizona + 50 more", "locations": [ { "city": "Birmingham", "state": "Alabama" }, { "city": "Phoenix", "state": "Arizona" }, { "city": "Tucson", "state": "Arizona" }, { "city": "La Jolla", "state": "California" }, { "city": "Loma Linda", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT03626688" }, { "nct_id": "NCT03449524", "title": "PRIMEx - A Study of 2 Doses of Oral CXA-10 in Pulmonary Arterial Hypertension (PAH)", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "PAH" ], "interventions": [ { "name": "75mg CXA-10", "type": "DRUG" }, { "name": "150mg CXA-10", "type": "DRUG" }, { "name": "Placebo", "type": "OTHER" } ], "intervention_types": [ "DRUG", "OTHER" ], "sponsor": "Complexa, Inc.", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "80 Years", "sex": "ALL", "summary": "18 Years to 80 Years" }, "enrollment_count": 69, "start_date": "2018-08-01", "completion_date": "2020-08-05", "has_results": false, "last_update_posted_date": "2020-08-10", "last_synced_at": "2026-10-13T06:14:41.246Z", "location_count": 40, "location_summary": "Birmingham, Alabama • Phoenix, Arizona • Tucson, Arizona + 34 more", "locations": [ { "city": "Birmingham", "state": "Alabama" }, { "city": "Phoenix", "state": "Arizona" }, { "city": "Tucson", "state": "Arizona" }, { "city": "San Francisco", "state": "California" }, { "city": "Aurora", "state": "Colorado" } ], "official_url": "https://clinicaltrials.gov/study/NCT03449524" }, { "nct_id": "NCT03840928", "title": "PatientSpot Formerly Known as ArthritisPower", "overall_status": "UNKNOWN", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Rheumatoid Arthritis", "Ankylosing Spondylitis", "Fibromyalgia", "Gout", "Crohn Disease", "Juvenile Idiopathic Arthritis", "Lupus Erythematosus", "Myositis", "Osteoarthritis", "Osteoporosis", "Psoriasis", "Psoriatic Arthritis", "Scleroderma", "Dermatomyositis", "Inflammatory Bowel Diseases", "Polymyositis", "Axial Spondyloarthritis", "Diffuse Idiopathic Skeletal Hyperostosis", "Polymyalgia Rheumatica", "Giant Cell Arteritis", "Temporal Arteritis", "Wegener", "Relapsing Polychondritis", "Undifferentiated Connective Tissue Disease", "Spinal Cord Injuries", "Alzheimer Disease", "Amyotrophic Lateral Sclerosis", "Ataxia", "Bell Palsy", "Brain Tumor", "Cerebral Aneurysm", "Epilepsy", "Guillain-Barre Syndrome", "Headache", "Head Injury", "Hydrocephalus", "Lumbar Disc Disease", "Meningitis", "Multiple Sclerosis", "Muscular Dystrophy", "Neurocutaneous Syndromes", "Parkinson Disease", "Stroke", "Cluster Headache", "Tension-Type Headache", "Chronic Obstructive Pulmonary Disease", "Asthma", "Lung Cancer", "Cystic Fibrosis", "Sleep Apnea", "Eczema", "Alopecia", "Chronic Inflammation", "Unstable Angina", "Heart Attack", "Heart Failure", "Arrythmia", "Valve Heart Disease", "High Blood Pressure", "Congenital Heart Disease", "Peripheral Arterial Disease", "Diabetes", "Chronic Liver Disease", "Obesity" ], "interventions": [], "intervention_types": [], "sponsor": "Global Healthy Living Foundation", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "19 Years", "maximum_age": null, "sex": "ALL", "summary": "19 Years and older" }, "enrollment_count": 40000, "start_date": "2015-04-01", "completion_date": "2025-03-01", "has_results": false, "last_update_posted_date": "2023-12-13", "last_synced_at": "2026-10-13T06:14:41.246Z", "location_count": 1, "location_summary": "Upper Nyack, New York", "locations": [ { "city": "Upper Nyack", "state": "New York" } ], "official_url": "https://clinicaltrials.gov/study/NCT03840928" }, { "nct_id": "NCT03459716", "title": "Endothelial Biomarkers of Systemic Sclerosis-associated Pulmonary Hypertension", "overall_status": "UNKNOWN", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Scleroderma", "Pulmonary Hypertension" ], "interventions": [ { "name": "No intervention", "type": "OTHER" } ], "intervention_types": [ "OTHER" ], "sponsor": "Louisiana State University Health Sciences Center in New Orleans", "sponsor_class": "OTHER", "healthy_volunteers": null, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 56, "start_date": "2018-06-01", "completion_date": "2021-12-01", "has_results": false, "last_update_posted_date": "2021-09-10", "last_synced_at": "2026-10-13T06:14:41.246Z", "location_count": 1, "location_summary": "New Orleans, Louisiana", "locations": [ { "city": "New Orleans", "state": "Louisiana" } ], "official_url": "https://clinicaltrials.gov/study/NCT03459716" }, { "nct_id": "NCT07217522", "title": "Rutgers University Study of the Genetics of Pulmonary Hypertension", "overall_status": "RECRUITING", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Pulmonary Hypertension", "Pulmonary Arterial Hypertension", "Pulmonary Arterial Hypertension (PAH) (WHO Group 1 PH)", "Pulmonary Arterial Hypertension Associated With Connective Tissue Disease", "Pulmonary Arterial Hypertension Associated With Connective Tissue Disease (Disorder)", "Pulmonary Arterial Hypertension Associated With Schistosomiasis (Disorder)", "Pulmonary Arterial Hypertension of Congenital Heart Disease", "Pulmonary Arterial and Chronic Thromboembolic Pulmonary Hypertension" ], "interventions": [ { "name": "Saliva sample", "type": "GENETIC" }, { "name": "Health surveys", "type": "OTHER" } ], "intervention_types": [ "GENETIC", "OTHER" ], "sponsor": "Rutgers, The State University of New Jersey", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 10000, "start_date": "2025-08-23", "completion_date": "2027-12-31", "has_results": false, "last_update_posted_date": "2025-11-03", "last_synced_at": "2026-10-13T06:14:41.246Z", "location_count": 1, "location_summary": "Piscataway, New Jersey", "locations": [ { "city": "Piscataway", "state": "New Jersey" } ], "official_url": "https://clinicaltrials.gov/study/NCT07217522" }, { "nct_id": "NCT03683186", "title": "A Study Evaluating the Long-Term Efficacy and Safety of Ralinepag in Subjects With PAH Via an Open-Label Extension", "overall_status": "ENROLLING_BY_INVITATION", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "PAH", "Pulmonary Hypertension", "Pulmonary Arterial Hypertension", "Hypertension", "Connective Tissue Diseases", "Familial Primary Pulmonary Hypertension", "Vascular Diseases", "Cardiovascular Diseases", "Hypertension, Pulmonary", "Lung Diseases", "Respiratory Tract Disease" ], "interventions": [ { "name": "Ralinepag", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "United Therapeutics", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 1000, "start_date": "2019-09-23", "completion_date": "2026-12", "has_results": false, "last_update_posted_date": "2026-10-06", "last_synced_at": "2026-10-13T06:14:41.246Z", "location_count": 48, "location_summary": "Phoenix, Arizona • Tucson, Arizona • La Jolla, California + 38 more", "locations": [ { "city": "Phoenix", "state": "Arizona" }, { "city": "Tucson", "state": "Arizona" }, { "city": "La Jolla", "state": "California" }, { "city": "Los Angeles", "state": "California" }, { "city": "Los Angeles", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT03683186" }, { "nct_id": "NCT03726398", "title": "CompRehensive Phenotypic Characterization of Patients With Scleroderma-Associated ILD and PH", "overall_status": "WITHDRAWN", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2", "PHASE3" ], "conditions": [ "Interstitial Lung Disease", "Scleroderma", "Pulmonary Hypertension" ], "interventions": [ { "name": "Opsumit 10 Mg Tablet", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Franz Rischard, DO", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 0, "start_date": "2018-09-01", "completion_date": "2020-08-03", "has_results": false, "last_update_posted_date": "2025-02-20", "last_synced_at": "2026-10-13T06:14:41.246Z", "location_count": 1, "location_summary": "Tucson, Arizona", "locations": [ { "city": "Tucson", "state": "Arizona" } ], "official_url": "https://clinicaltrials.gov/study/NCT03726398" }, { "nct_id": "NCT06104228", "title": "129 Xenon MRI as a Biomarker for Diagnosis and Response to Therapy in Pulmonary Arterial Hypertension (PAH)", "overall_status": "RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Pulmonary Arterial Hypertension", "Idiopathic Pulmonary Arterial Hypertension", "Pulmonary Arterial Hypertension Associated With Connective Tissue Disease (Disorder)", "Connective Tissue Diseases" ], "interventions": [ { "name": "129Xe Hyperpolarized", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Bastiaan Driehuys", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "75 Years", "sex": "ALL", "summary": "18 Years to 75 Years" }, "enrollment_count": 20, "start_date": "2024-08-12", "completion_date": "2027-03-31", "has_results": false, "last_update_posted_date": "2026-02-24", "last_synced_at": "2026-10-13T06:14:41.246Z", "location_count": 1, "location_summary": "Durham, North Carolina", "locations": [ { "city": "Durham", "state": "North Carolina" } ], "official_url": "https://clinicaltrials.gov/study/NCT06104228" } ] }