{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Constipation&page=5", "query": { "condition": "Constipation", "page": 5 }, "page_size": 10 }, "pagination": { "page": 5, "page_size": 10, "total_count": 405, "total_pages": 41, "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Constipation&page=6&page_size=10", "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Constipation&page=4&page_size=10" }, "source": "remote", "last_synced_at": "2026-10-20T14:32:56.274Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT03781791", "title": "Orally Administered ENT-01 for Parkinson's Disease-Related Constipation (KARMET)", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Constipation", "Parkinson Disease" ], "interventions": [ { "name": "Active Investigational Treatment ENT-01", "type": "DRUG" }, { "name": "Placebo Treatment", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Enterin Inc.", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "30 Years", "maximum_age": "90 Years", "sex": "ALL", "summary": "30 Years to 90 Years" }, "enrollment_count": 151, "start_date": "2018-12-10", "completion_date": "2021-12-14", "has_results": true, "last_update_posted_date": "2024-02-20", "last_synced_at": "2026-10-20T14:32:56.274Z", "location_count": 51, "location_summary": "Sun City, Arizona • Little Rock, Arkansas • Fountain Valley, California + 44 more", "locations": [ { "city": "Sun City", "state": "Arizona" }, { "city": "Little Rock", "state": "Arkansas" }, { "city": "Fountain Valley", "state": "California" }, { "city": "Fresno", "state": "California" }, { "city": "Oxnard", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT03781791" }, { "nct_id": "NCT04961840", "title": "A Study to Assess Maternal and Fetal Outcomes After Taking Prucalopride During Pregnancy", "overall_status": "ACTIVE_NOT_RECRUITING", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Constipation", "Pregnancy" ], "interventions": [ { "name": "No Intervention", "type": "OTHER" } ], "intervention_types": [ "OTHER" ], "sponsor": "Takeda", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "44 Years", "sex": "FEMALE", "summary": "18 Years to 44 Years · Female only" }, "enrollment_count": 100, "start_date": "2022-01-01", "completion_date": "2027-06-30", "has_results": false, "last_update_posted_date": "2026-10-13", "last_synced_at": "2026-10-20T14:32:56.274Z", "location_count": 1, "location_summary": "Boston, Massachusetts", "locations": [ { "city": "Boston", "state": "Massachusetts" } ], "official_url": "https://clinicaltrials.gov/study/NCT04961840" }, { "nct_id": "NCT00171522", "title": "Preference of Tegaserod vs. PEG 3350 in Patients With Constipation", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Constipation" ], "interventions": [ { "name": "Tegaserod and Polyethylene Glycol 3350", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Novartis", "sponsor_class": "INDUSTRY", "healthy_volunteers": null, "eligibility": { "minimum_age": "18 Years", "maximum_age": "64 Years", "sex": "FEMALE", "summary": "18 Years to 64 Years · Female only" }, "enrollment_count": 52, "start_date": "2005-05", "completion_date": "2005-09", "has_results": false, "last_update_posted_date": "2016-03-03", "last_synced_at": "2026-10-20T14:32:56.274Z", "location_count": 14, "location_summary": "Oro Valley, Arizona • Phoenix, Arizona • Tucson, Arizona + 11 more", "locations": [ { "city": "Oro Valley", "state": "Arizona" }, { "city": "Phoenix", "state": "Arizona" }, { "city": "Tucson", "state": "Arizona" }, { "city": "Buena Park", "state": "California" }, { "city": "Boca Raton", "state": "Florida" } ], "official_url": "https://clinicaltrials.gov/study/NCT00171522" }, { "nct_id": "NCT06253689", "title": "Impact of Defecation Posture on Ease of First Bowel Movement Following Posterior Repair", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Postoperative Constipation", "Pelvic Organ Prolapse Vaginal Surgery", "Defecation Function" ], "interventions": [ { "name": "Defecation Posture Modification Device", "type": "DEVICE" } ], "intervention_types": [ "DEVICE" ], "sponsor": "TriHealth Inc.", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "FEMALE", "summary": "18 Years and older · Female only" }, "enrollment_count": 160, "start_date": "2024-02-19", "completion_date": "2025-03-21", "has_results": false, "last_update_posted_date": "2025-04-18", "last_synced_at": "2026-10-20T14:32:56.274Z", "location_count": 3, "location_summary": "Cincinnati, Ohio", "locations": [ { "city": "Cincinnati", "state": "Ohio" }, { "city": "Cincinnati", "state": "Ohio" }, { "city": "Cincinnati", "state": "Ohio" } ], "official_url": "https://clinicaltrials.gov/study/NCT06253689" }, { "nct_id": "NCT01827592", "title": "26 Week Efficacy and Safety Trial for Patients With Chronic Idiopathic Constipation", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Chronic Idiopathic Constipation" ], "interventions": [ { "name": "Elobixibat 10 mg", "type": "DRUG" }, { "name": "Elobixibat 5 mg", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Ferring Pharmaceuticals", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 376, "start_date": "2013-04", "completion_date": "2014-05", "has_results": true, "last_update_posted_date": "2015-10-20", "last_synced_at": "2026-10-20T14:32:56.274Z", "location_count": 46, "location_summary": "Birmingham, Alabama • Foley, Alabama • Tucson, Arizona + 39 more", "locations": [ { "city": "Birmingham", "state": "Alabama" }, { "city": "Foley", "state": "Alabama" }, { "city": "Tucson", "state": "Arizona" }, { "city": "Cerritos", "state": "California" }, { "city": "Chula Vista", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT01827592" }, { "nct_id": "NCT02559817", "title": "A Safety and Efficacy Study of a Range of Linaclotide Doses Administered Orally to Children Ages 7-17 Years, With Irritable Bowel Syndrome With Constipation", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Irritable Bowel Syndrome With Constipation" ], "interventions": [ { "name": "Linaclotide Dose A", "type": "DRUG" }, { "name": "Linaclotide Dose B", "type": "DRUG" }, { "name": "Linaclotide Dose C", "type": "DRUG" }, { "name": "Linaclotide Approved Adult Dose", "type": "DRUG" }, { "name": "Matching Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Forest Laboratories", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "7 Years", "maximum_age": "17 Years", "sex": "ALL", "summary": "7 Years to 17 Years" }, "enrollment_count": 101, "start_date": "2015-11-01", "completion_date": "2019-08-30", "has_results": true, "last_update_posted_date": "2020-12-28", "last_synced_at": "2026-10-20T14:32:56.274Z", "location_count": 46, "location_summary": "Hot Springs, Arkansas • Little Rock, Arkansas • Anaheim, California + 39 more", "locations": [ { "city": "Hot Springs", "state": "Arkansas" }, { "city": "Little Rock", "state": "Arkansas" }, { "city": "Anaheim", "state": "California" }, { "city": "Corona", "state": "California" }, { "city": "Costa Mesa", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT02559817" }, { "nct_id": "NCT01288508", "title": "Investigation of Supra Fiber in the Treatment of Adults With Constipation", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Constipation" ], "interventions": [ { "name": "Supra Fiber", "type": "DIETARY_SUPPLEMENT" }, { "name": "Psyllium", "type": "DIETARY_SUPPLEMENT" } ], "intervention_types": [ "DIETARY_SUPPLEMENT" ], "sponsor": "Augusta University", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "75 Years", "sex": "ALL", "summary": "18 Years to 75 Years" }, "enrollment_count": 89, "start_date": "2010-10", "completion_date": "2014-09", "has_results": false, "last_update_posted_date": "2014-09-17", "last_synced_at": "2026-10-20T14:32:56.274Z", "location_count": 1, "location_summary": "Iowa City, Iowa", "locations": [ { "city": "Iowa City", "state": "Iowa" } ], "official_url": "https://clinicaltrials.gov/study/NCT01288508" }, { "nct_id": "NCT06763809", "title": "A Randomized Placebo-Controlled Study to Evaluate the Effects of a Gummy and Capsule Supplement on Symptoms of Premenstrual Syndrome", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "PMS", "Menstrual Cramp", "Mood Change" ], "interventions": [ { "name": "PMS Capsule", "type": "DIETARY_SUPPLEMENT" }, { "name": "Capsule Placebo", "type": "DIETARY_SUPPLEMENT" }, { "name": "PMS Gummy", "type": "DIETARY_SUPPLEMENT" }, { "name": "Gummy Placebo", "type": "DIETARY_SUPPLEMENT" } ], "intervention_types": [ "DIETARY_SUPPLEMENT" ], "sponsor": "Semaine Health", "sponsor_class": "INDUSTRY", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "FEMALE", "summary": "18 Years and older · Female only" }, "enrollment_count": 176, "start_date": "2024-09-04", "completion_date": "2024-12-12", "has_results": false, "last_update_posted_date": "2025-01-08", "last_synced_at": "2026-10-20T14:32:56.274Z", "location_count": 1, "location_summary": "Las Vegas, Nevada", "locations": [ { "city": "Las Vegas", "state": "Nevada" } ], "official_url": "https://clinicaltrials.gov/study/NCT06763809" }, { "nct_id": "NCT01399996", "title": "Influence of a Delivery System on the Efficacy of a Probiotic Intervention", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "Delayed Transit Time", "Irregular Bowel Function" ], "interventions": [ { "name": "Yogurt smoothie without probiotic", "type": "DIETARY_SUPPLEMENT" }, { "name": "Yogurt smoothie with probiotic added post fermentation", "type": "DIETARY_SUPPLEMENT" }, { "name": "Yogurt smoothie with probiotic added pre-fermentation", "type": "DIETARY_SUPPLEMENT" }, { "name": "A capsule containing the probiotic", "type": "DIETARY_SUPPLEMENT" } ], "intervention_types": [ "DIETARY_SUPPLEMENT" ], "sponsor": "Penn State University", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "40 Years", "sex": "ALL", "summary": "18 Years to 40 Years" }, "enrollment_count": 36, "start_date": "2012-04", "completion_date": "2014-08", "has_results": false, "last_update_posted_date": "2023-08-21", "last_synced_at": "2026-10-20T14:32:56.274Z", "location_count": 1, "location_summary": "University Park, Pennsylvania", "locations": [ { "city": "University Park", "state": "Pennsylvania" } ], "official_url": "https://clinicaltrials.gov/study/NCT01399996" }, { "nct_id": "NCT02406859", "title": "Utility of an Animated Bowel Biofeedback Training Routine to Improve Bowel Function in Individuals With SCI", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Spinal Cord Injury", "Constipation", "Fecal Incontinence", "Neurogenic Bowel" ], "interventions": [ { "name": "Bowel Biofeedback", "type": "BEHAVIORAL" }, { "name": "Anorectal Manometry", "type": "BEHAVIORAL" } ], "intervention_types": [ "BEHAVIORAL" ], "sponsor": "VA Office of Research and Development", "sponsor_class": "FED", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "75 Years", "sex": "ALL", "summary": "18 Years to 75 Years" }, "enrollment_count": 50, "start_date": "2013-07-01", "completion_date": "2017-12-29", "has_results": true, "last_update_posted_date": "2021-09-17", "last_synced_at": "2026-10-20T14:32:56.274Z", "location_count": 1, "location_summary": "The Bronx, New York", "locations": [ { "city": "The Bronx", "state": "New York" } ], "official_url": "https://clinicaltrials.gov/study/NCT02406859" } ] }