{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Constriction&page=14",
    "query": {
      "condition": "Constriction",
      "page": 14
    },
    "page_size": 10
  },
  "pagination": {
    "page": 14,
    "page_size": 10,
    "total_count": 1008,
    "total_pages": 101,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Constriction&page=15&page_size=10",
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Constriction&page=13&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-10-23T12:31:12.861Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT01988766",
      "title": "Risk of Central Venous Stenosis in Patients With Chronic Renal Failure After IJ Line Placement",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Thrombosis"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "University of Chicago",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 1424,
      "start_date": "2012-10",
      "completion_date": "2014-08",
      "has_results": false,
      "last_update_posted_date": "2014-11-24",
      "last_synced_at": "2026-10-23T12:31:12.861Z",
      "location_count": 1,
      "location_summary": "Chicago, Illinois",
      "locations": [
        {
          "city": "Chicago",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01988766"
    },
    {
      "nct_id": "NCT03549559",
      "title": "Imaging Histone Deacetylase in the Heart",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Heart Failure With Normal Ejection Fraction",
        "Left Ventricular Hypertrophy",
        "Aortic Valve Stenosis",
        "Diabetes"
      ],
      "interventions": [
        {
          "name": "11C-Martinostat",
          "type": "DRUG"
        },
        {
          "name": "PET-MRI",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DRUG",
        "DEVICE"
      ],
      "sponsor": "Massachusetts General Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "85 Years",
        "sex": "ALL",
        "summary": "18 Years to 85 Years"
      },
      "enrollment_count": 96,
      "start_date": "2018-09-07",
      "completion_date": "2026-09-01",
      "has_results": false,
      "last_update_posted_date": "2025-12-22",
      "last_synced_at": "2026-10-23T12:31:12.861Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03549559"
    },
    {
      "nct_id": "NCT02697435",
      "title": "Making Better Lives: Patient-Focused Care for Low Back Pain (LBP)",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Chronic Low Back Pain",
        "Hip Ostearthritis",
        "Myofascial Pain Syndrome",
        "Fibromyalgia",
        "Depression",
        "Maladaptive Coping",
        "Lumbar Spinal Stenosis",
        "Insomnia",
        "Sacroiliac Joint Pain",
        "Lateral Hip and Thigh Pain",
        "Anxiety",
        "Dementia",
        "Recent Leg Length Discrepancy"
      ],
      "interventions": [
        {
          "name": "Patient-Centered Care",
          "type": "OTHER"
        },
        {
          "name": "Imaging-Directed Care",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "VA Office of Research and Development",
      "sponsor_class": "FED",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "60 Years",
        "maximum_age": "89 Years",
        "sex": "ALL",
        "summary": "60 Years to 89 Years"
      },
      "enrollment_count": 55,
      "start_date": "2016-04-01",
      "completion_date": "2018-08-31",
      "has_results": true,
      "last_update_posted_date": "2019-08-19",
      "last_synced_at": "2026-10-23T12:31:12.861Z",
      "location_count": 2,
      "location_summary": "Pittsburgh, Pennsylvania • Richmond, Virginia",
      "locations": [
        {
          "city": "Pittsburgh",
          "state": "Pennsylvania"
        },
        {
          "city": "Richmond",
          "state": "Virginia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02697435"
    },
    {
      "nct_id": "NCT07191860",
      "title": "Paclitaxel-Coated Pulmonary Balloon for the Treatment of Benign Central Airway Stenosis",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Adult Subjects With Symptomatic Benign Airway Obstruction",
        "Adult Benign Central Airway Stenosis",
        "Adult Tracheobronchial Stenosis",
        "Tracheal Stenosis",
        "Central Airway Stenosis",
        "Central Airway Obstruction"
      ],
      "interventions": [
        {
          "name": "The Airiver Pulmonary drug-coated balloon (DCB) dilation",
          "type": "COMBINATION_PRODUCT"
        },
        {
          "name": "Commercial airway balloon dilation",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "COMBINATION_PRODUCT",
        "DEVICE"
      ],
      "sponsor": "Airiver Medical, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "22 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "22 Years and older"
      },
      "enrollment_count": 200,
      "start_date": "2026-02-24",
      "completion_date": "2030-11-01",
      "has_results": false,
      "last_update_posted_date": "2026-06-18",
      "last_synced_at": "2026-10-23T12:31:12.861Z",
      "location_count": 1,
      "location_summary": "Baltimore, Maryland",
      "locations": [
        {
          "city": "Baltimore",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07191860"
    },
    {
      "nct_id": "NCT01556568",
      "title": "Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of MEK162 in Noonan Syndrome Hypertrophic Cardiomyopathy",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Cardiomegaly"
      ],
      "interventions": [
        {
          "name": "MEK162",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Array Biopharma, now a wholly owned subsidiary of Pfizer",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 0,
      "start_date": "2012-02",
      "completion_date": null,
      "has_results": false,
      "last_update_posted_date": "2020-10-06",
      "last_synced_at": "2026-10-23T12:31:12.861Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01556568"
    },
    {
      "nct_id": "NCT01205789",
      "title": "EXCEL Clinical Trial (Universal Registry)",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Chronic Coronary Occlusion",
        "Left Main Coronary Artery Disease",
        "Stent Thrombosis",
        "Vascular Disease",
        "Myocardial Ischemia",
        "Coronary Artery Stenosis",
        "Coronary Disease",
        "Coronary Artery Disease",
        "Coronary Restenosis"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Abbott Medical Devices",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 1000,
      "start_date": "2010-10",
      "completion_date": "2012-09",
      "has_results": false,
      "last_update_posted_date": "2012-12-04",
      "last_synced_at": "2026-10-23T12:31:12.861Z",
      "location_count": 1,
      "location_summary": "Santa Clara, California",
      "locations": [
        {
          "city": "Santa Clara",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01205789"
    },
    {
      "nct_id": "NCT06680427",
      "title": "Siegel™ Transcatheter Aortic Valve Replacement System (TAVR) Early Feasibility Study",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Aortic Stenosis Symptomatic"
      ],
      "interventions": [
        {
          "name": "Siegel Transcatheter Aortic Valve (TAVR)",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "MiRus",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "50 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "50 Years and older"
      },
      "enrollment_count": 30,
      "start_date": "2025-03-26",
      "completion_date": "2025-12",
      "has_results": false,
      "last_update_posted_date": "2025-12-03",
      "last_synced_at": "2026-10-23T12:31:12.861Z",
      "location_count": 8,
      "location_summary": "Los Angeles, California • Palo Alto, California • Naples, Florida + 5 more",
      "locations": [
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Palo Alto",
          "state": "California"
        },
        {
          "city": "Naples",
          "state": "Florida"
        },
        {
          "city": "Atlanta",
          "state": "Georgia"
        },
        {
          "city": "Rochester",
          "state": "Minnesota"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06680427"
    },
    {
      "nct_id": "NCT06917586",
      "title": "Mosaic Mitral Valve: Long-Term Outcomes in Patients Under 65",
      "overall_status": "RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Valve Disease, Heart",
        "Valve Replacement",
        "Valve Regurgitation, Mitral",
        "Valve Heart Stenosis"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Michael Moront",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 300,
      "start_date": "2025-01-01",
      "completion_date": "2027-07-01",
      "has_results": false,
      "last_update_posted_date": "2026-02-20",
      "last_synced_at": "2026-10-23T12:31:12.861Z",
      "location_count": 1,
      "location_summary": "Toledo, Ohio",
      "locations": [
        {
          "city": "Toledo",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06917586"
    },
    {
      "nct_id": "NCT06749145",
      "title": "Deep Learning Enhanced Detection of Aortic Stenosis - The DETECT-AS-Diagnostic Study",
      "overall_status": "ENROLLING_BY_INVITATION",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Aortic Stenosis"
      ],
      "interventions": [
        {
          "name": "Portable 1-lead electrocardiogram",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Point-of-care ultrasound",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "AI-ECG risk algorithm",
          "type": "OTHER"
        },
        {
          "name": "AI-POCUS",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DIAGNOSTIC_TEST",
        "OTHER"
      ],
      "sponsor": "Yale University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "70 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "70 Years and older"
      },
      "enrollment_count": 410,
      "start_date": "2025-09-16",
      "completion_date": "2028-08-31",
      "has_results": false,
      "last_update_posted_date": "2026-10-06",
      "last_synced_at": "2026-10-23T12:31:12.861Z",
      "location_count": 3,
      "location_summary": "New Haven, Connecticut • New York, New York • Houston, Texas",
      "locations": [
        {
          "city": "New Haven",
          "state": "Connecticut"
        },
        {
          "city": "New York",
          "state": "New York"
        },
        {
          "city": "Houston",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06749145"
    },
    {
      "nct_id": "NCT04395495",
      "title": "RASopathy Biorepository",
      "overall_status": "RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "RAS Mutation",
        "Neurofibromatosis 1",
        "Noonan Syndrome",
        "Noonan Syndrome With Multiple Lentigines",
        "Noonan Neurofibromatosis Syndrome",
        "Cardiofaciocutaneous Syndrome",
        "Costello Syndrome",
        "Legius Syndrome",
        "Smith-Kingsmore Syndrome",
        "MTOR Gene Mutation",
        "GATOR-1 Gene Mutation",
        "SYNGAP1-Related Intellectual Disability",
        "DLG4",
        "MAPK1 Gene Mutation"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Children's Hospital Medical Center, Cincinnati",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 1000,
      "start_date": "2017-06-27",
      "completion_date": "2065-12",
      "has_results": false,
      "last_update_posted_date": "2025-12-18",
      "last_synced_at": "2026-10-23T12:31:12.861Z",
      "location_count": 1,
      "location_summary": "Cincinnati, Ohio",
      "locations": [
        {
          "city": "Cincinnati",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04395495"
    }
  ]
}