{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Constriction&page=27",
    "query": {
      "condition": "Constriction",
      "page": 27
    },
    "page_size": 10
  },
  "pagination": {
    "page": 27,
    "page_size": 10,
    "total_count": 1008,
    "total_pages": 101,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Constriction&page=28&page_size=10",
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Constriction&page=26&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-10-24T21:06:27.309Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT06269640",
      "title": "NHLBI SESAME (SEptal Scoring Along Midline Endocardium) Early Feasibility Study",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Hypertrophic Cardiomyopathy",
        "Left Ventricular Septal Hypertrophy",
        "Mitral Valve Disease",
        "Aortic Valve Stenosis"
      ],
      "interventions": [
        {
          "name": "Septal Scoring Along Midline Endocardium",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "National Heart, Lung, and Blood Institute (NHLBI)",
      "sponsor_class": "NIH",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "99 Years",
        "sex": "ALL",
        "summary": "21 Years to 99 Years"
      },
      "enrollment_count": 1,
      "start_date": "2024-12-18",
      "completion_date": "2024-12-23",
      "has_results": true,
      "last_update_posted_date": "2025-12-18",
      "last_synced_at": "2026-10-24T21:06:27.309Z",
      "location_count": 1,
      "location_summary": "Atlanta, Georgia",
      "locations": [
        {
          "city": "Atlanta",
          "state": "Georgia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06269640"
    },
    {
      "nct_id": "NCT02851290",
      "title": "Effect of Caudal and Penile Block on Hypospadias Repair Complications",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Hypospadias"
      ],
      "interventions": [
        {
          "name": "Caudal block anesthesia",
          "type": "PROCEDURE"
        },
        {
          "name": "Dorsal penile nerve block anesthesia",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Baylor College of Medicine",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "4 Months",
        "maximum_age": "4 Years",
        "sex": "MALE",
        "summary": "4 Months to 4 Years · Male only"
      },
      "enrollment_count": 66,
      "start_date": "2016-07",
      "completion_date": "2023-05-19",
      "has_results": false,
      "last_update_posted_date": "2023-05-22",
      "last_synced_at": "2026-10-24T21:06:27.309Z",
      "location_count": 1,
      "location_summary": "Houston, Texas",
      "locations": [
        {
          "city": "Houston",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02851290"
    },
    {
      "nct_id": "NCT01688024",
      "title": "Mitomycin C Therapy for Patients With Primary Sclerosing Cholangitis",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Primary Sclerosing Cholangitis"
      ],
      "interventions": [
        {
          "name": "Mitomycin C",
          "type": "DRUG"
        },
        {
          "name": "Normal saline",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Li, Zhiping, M.D.",
      "sponsor_class": "INDIV",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 130,
      "start_date": "2012-09",
      "completion_date": "2019-09",
      "has_results": false,
      "last_update_posted_date": "2016-09-07",
      "last_synced_at": "2026-10-24T21:06:27.309Z",
      "location_count": 1,
      "location_summary": "Baltimore, Maryland",
      "locations": [
        {
          "city": "Baltimore",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01688024"
    },
    {
      "nct_id": "NCT02927990",
      "title": "Contrast Volume Reduction During PCI With the Use of a New Assisting Software Package",
      "overall_status": "TERMINATED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Coronary Stenosis",
        "Coronary Occlusion"
      ],
      "interventions": [
        {
          "name": "Percutaneous Coronary Intervention",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Philips Clinical & Medical Affairs Global",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 80,
      "start_date": "2017-12-15",
      "completion_date": "2019-06-30",
      "has_results": true,
      "last_update_posted_date": "2024-12-06",
      "last_synced_at": "2026-10-24T21:06:27.309Z",
      "location_count": 1,
      "location_summary": "New York, New York",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02927990"
    },
    {
      "nct_id": "NCT01344447",
      "title": "Gadobutrol Enhanced MRA of the Supra-aortic Vessels",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Carotid Stenosis"
      ],
      "interventions": [
        {
          "name": "Gadobutrol (Gadovist, BAY86-4875)",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Bayer",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 479,
      "start_date": "2011-05-12",
      "completion_date": "2014-05-28",
      "has_results": true,
      "last_update_posted_date": "2019-01-04",
      "last_synced_at": "2026-10-24T21:06:27.309Z",
      "location_count": 15,
      "location_summary": "Tucson, Arizona • Jacksonville, Florida • Savannah, Georgia + 12 more",
      "locations": [
        {
          "city": "Tucson",
          "state": "Arizona"
        },
        {
          "city": "Jacksonville",
          "state": "Florida"
        },
        {
          "city": "Savannah",
          "state": "Georgia"
        },
        {
          "city": "Louisville",
          "state": "Kentucky"
        },
        {
          "city": "Baltimore",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01344447"
    },
    {
      "nct_id": "NCT05838547",
      "title": "CANF-Comb-II PET-MR in Atherosclerosis Multisite",
      "overall_status": "RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Carotid Atherosclerosis",
        "Asymptomatic Carotid Artery Stenosis",
        "Carotid Artery Atheroma"
      ],
      "interventions": [
        {
          "name": "64Cu-25%-CANF-Comb",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Washington University School of Medicine",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 80,
      "start_date": "2023-03-21",
      "completion_date": "2027-05-31",
      "has_results": false,
      "last_update_posted_date": "2026-03-23",
      "last_synced_at": "2026-10-24T21:06:27.309Z",
      "location_count": 2,
      "location_summary": "Los Angeles, California • St Louis, Missouri",
      "locations": [
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "St Louis",
          "state": "Missouri"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05838547"
    },
    {
      "nct_id": "NCT03042104",
      "title": "EARLY TAVR: Evaluation of TAVR Compared to Surveillance for Patients With Asymptomatic Severe Aortic Stenosis",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Heart Diseases",
        "Aortic Stenosis, Severe"
      ],
      "interventions": [
        {
          "name": "Edwards SAPIEN 3 / SAPIEN 3 Ultra THV",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Edwards Lifesciences",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "65 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "65 Years and older"
      },
      "enrollment_count": 901,
      "start_date": "2017-07-12",
      "completion_date": "2032-03",
      "has_results": false,
      "last_update_posted_date": "2024-05-13",
      "last_synced_at": "2026-10-24T21:06:27.309Z",
      "location_count": 74,
      "location_summary": "Phoenix, Arizona • Burlingame, California • Los Angeles, California + 62 more",
      "locations": [
        {
          "city": "Phoenix",
          "state": "Arizona"
        },
        {
          "city": "Burlingame",
          "state": "California"
        },
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Newport Beach",
          "state": "California"
        },
        {
          "city": "Pasadena",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03042104"
    },
    {
      "nct_id": "NCT04604652",
      "title": "Open-Label Study of HTD1801 in Adult Subjects With Primary Biliary Cholangitis",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Primary Biliary Cholangitis",
        "Primary Biliary Cirrhosis",
        "Cholangitis",
        "Cholestasis",
        "Biliary Tract Diseases",
        "Bile Duct Stricture"
      ],
      "interventions": [
        {
          "name": "HTD1801 (BUDCA)",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "HighTide Therapeutics (Hong Kong) Limited",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "18 Years to 75 Years"
      },
      "enrollment_count": 24,
      "start_date": "2021-05-27",
      "completion_date": "2022-05-31",
      "has_results": true,
      "last_update_posted_date": "2026-08-25",
      "last_synced_at": "2026-10-24T21:06:27.309Z",
      "location_count": 12,
      "location_summary": "Miami, Florida • Atlanta, Georgia • Boston, Massachusetts + 9 more",
      "locations": [
        {
          "city": "Miami",
          "state": "Florida"
        },
        {
          "city": "Atlanta",
          "state": "Georgia"
        },
        {
          "city": "Boston",
          "state": "Massachusetts"
        },
        {
          "city": "Detroit",
          "state": "Michigan"
        },
        {
          "city": "St Louis",
          "state": "Missouri"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04604652"
    },
    {
      "nct_id": "NCT00395785",
      "title": "Evaluation of the TriActiv ProGuard System During Carotid Artery Stenting",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2",
        "PHASE3"
      ],
      "conditions": [
        "Carotid Stenosis"
      ],
      "interventions": [
        {
          "name": "Carotid Stent Implantation",
          "type": "DEVICE"
        },
        {
          "name": "Embolic Protection",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Kensey Nash Corporation",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 400,
      "start_date": "2006-11",
      "completion_date": "2007-06",
      "has_results": false,
      "last_update_posted_date": "2007-07-25",
      "last_synced_at": "2026-10-24T21:06:27.309Z",
      "location_count": 31,
      "location_summary": "Birmingham, Alabama • Fairhope, Alabama • Beverly Hills, California + 25 more",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        },
        {
          "city": "Fairhope",
          "state": "Alabama"
        },
        {
          "city": "Beverly Hills",
          "state": "California"
        },
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Mountain View",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00395785"
    },
    {
      "nct_id": "NCT01714804",
      "title": "Efficacy and Safety of Integra Accell Evo3 DBM in Instrumented Lumbar Spine Fusion",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Stenosis",
        "Spondylosis",
        "Degenerative Changes"
      ],
      "interventions": [
        {
          "name": "Accell Evo3 Prospective Use",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "SeaSpine, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 30,
      "start_date": "2012-08",
      "completion_date": "2016-10",
      "has_results": true,
      "last_update_posted_date": "2018-01-23",
      "last_synced_at": "2026-10-24T21:06:27.309Z",
      "location_count": 1,
      "location_summary": "Durango, Colorado",
      "locations": [
        {
          "city": "Durango",
          "state": "Colorado"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01714804"
    }
  ]
}