{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Contact+Lens+Wear",
    "query": {
      "condition": "Contact Lens Wear"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 85,
    "total_pages": 9,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Contact+Lens+Wear&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-07-23T05:33:01.884Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT00724269",
      "title": "Comparison of OPTI-FREE RepleniSH and ReNu Multi-Plus Lens Care Regimens on Corneal Epithelium",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Contact Lens Wear"
      ],
      "interventions": [
        {
          "name": "OPTI-FREE RepleniSH",
          "type": "DEVICE"
        },
        {
          "name": "ReNu MultiPlus MPS",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Alcon Research",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 20,
      "start_date": "2009-10",
      "completion_date": "2011-07",
      "has_results": false,
      "last_update_posted_date": "2012-10-01",
      "last_synced_at": "2026-07-23T05:33:01.884Z",
      "location_count": 1,
      "location_summary": "Fort Worth, Texas",
      "locations": [
        {
          "city": "Fort Worth",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00724269"
    },
    {
      "nct_id": "NCT06689696",
      "title": "24-hour Wear Performance and Safety Study of Smartlens miLens Contact Lens for IOP Monitoring",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Glaucoma",
        "GLAUCOMA 1, OPEN ANGLE, D (Disorder)",
        "Ocular Hypertension",
        "Ocular Hypertension (OH)",
        "Ocular Hypertension Glaucoma",
        "IOP",
        "Intraocular Pressure",
        "Glaucoma Open-Angle",
        "Glaucoma and Ocular Hypertension",
        "Glaucoma Patients and Healthy Controls",
        "Normal Tension Glaucoma (NTG)"
      ],
      "interventions": [
        {
          "name": "miLens system",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Smartlens, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "22 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "22 Years to 80 Years"
      },
      "enrollment_count": 86,
      "start_date": "2025-02-19",
      "completion_date": "2026-01-06",
      "has_results": false,
      "last_update_posted_date": "2026-04-01",
      "last_synced_at": "2026-07-23T05:33:01.884Z",
      "location_count": 3,
      "location_summary": "Fullerton, California • Petaluma, California • Torrance, California",
      "locations": [
        {
          "city": "Fullerton",
          "state": "California"
        },
        {
          "city": "Petaluma",
          "state": "California"
        },
        {
          "city": "Torrance",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06689696"
    },
    {
      "nct_id": "NCT06749496",
      "title": "Evaluation of Delefilcon A and Senofilcon A Daily Disposable Toric Soft Contact Lenses Over One Week of Wear",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Astigmatism"
      ],
      "interventions": [
        {
          "name": "Test Lens",
          "type": "DEVICE"
        },
        {
          "name": "Control Lens",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Johnson & Johnson Vision Care, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "39 Years",
        "sex": "ALL",
        "summary": "18 Years to 39 Years"
      },
      "enrollment_count": 134,
      "start_date": "2025-01-07",
      "completion_date": "2025-03-20",
      "has_results": true,
      "last_update_posted_date": "2026-07-06",
      "last_synced_at": "2026-07-23T05:33:01.884Z",
      "location_count": 12,
      "location_summary": "Jacksonville, Florida • Longwood, Florida • Maitland, Florida + 9 more",
      "locations": [
        {
          "city": "Jacksonville",
          "state": "Florida"
        },
        {
          "city": "Longwood",
          "state": "Florida"
        },
        {
          "city": "Maitland",
          "state": "Florida"
        },
        {
          "city": "Pittsburg",
          "state": "Kansas"
        },
        {
          "city": "Bloomfield Hills",
          "state": "Michigan"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06749496"
    },
    {
      "nct_id": "NCT07303920",
      "title": "Wear Experience With Daily Disposable Contact Lenses for Astigmatism Over a Long-Wear Day",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Astigmatism"
      ],
      "interventions": [
        {
          "name": "Daily disposable contact lenses for astigmatism",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Ohio State University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "40 Years",
        "sex": "ALL",
        "summary": "18 Years to 40 Years"
      },
      "enrollment_count": 40,
      "start_date": "2026-03-04",
      "completion_date": "2026-06-30",
      "has_results": false,
      "last_update_posted_date": "2026-03-25",
      "last_synced_at": "2026-07-23T05:33:01.884Z",
      "location_count": 1,
      "location_summary": "Columbus, Ohio",
      "locations": [
        {
          "city": "Columbus",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07303920"
    },
    {
      "nct_id": "NCT00522288",
      "title": "Effects of Contact Lens Wear on Children's Self-Perceptions",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Myopia"
      ],
      "interventions": [
        {
          "name": "Soft contact lenses",
          "type": "DEVICE"
        },
        {
          "name": "Spectacle",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Ohio State University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "8 Years",
        "maximum_age": "11 Years",
        "sex": "ALL",
        "summary": "8 Years to 11 Years"
      },
      "enrollment_count": 484,
      "start_date": "2003-09",
      "completion_date": "2007-10",
      "has_results": false,
      "last_update_posted_date": "2011-03-21",
      "last_synced_at": "2026-07-23T05:33:01.884Z",
      "location_count": 5,
      "location_summary": "Boston, Massachusetts • Columbus, Ohio • Forest Grove, Oregon + 2 more",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        },
        {
          "city": "Columbus",
          "state": "Ohio"
        },
        {
          "city": "Forest Grove",
          "state": "Oregon"
        },
        {
          "city": "Memphis",
          "state": "Tennessee"
        },
        {
          "city": "Houston",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00522288"
    },
    {
      "nct_id": "NCT01015768",
      "title": "Corneal Staining and Physiological Compromise After Eight Hours of Soft Contact Lens Wear",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Contact Lens-induced Corneal Fluorescein Staining"
      ],
      "interventions": [
        {
          "name": "ReNu Multiplus multipurpose disinfecting solution",
          "type": "DEVICE"
        },
        {
          "name": "Control",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Southern California College of Optometry at Marshall B. Ketchum University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 30,
      "start_date": "2009-10",
      "completion_date": "2010-01",
      "has_results": true,
      "last_update_posted_date": "2020-09-18",
      "last_synced_at": "2026-07-23T05:33:01.884Z",
      "location_count": 1,
      "location_summary": "Fullerton, California",
      "locations": [
        {
          "city": "Fullerton",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01015768"
    },
    {
      "nct_id": "NCT00717249",
      "title": "Vistakon Investigational Contact Lenses Worn for Daily Wear",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Myopia"
      ],
      "interventions": [
        {
          "name": "galyifilcon A control lens",
          "type": "DEVICE"
        },
        {
          "name": "galyfilcon A with a silver additive",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Johnson & Johnson Vision Care, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 529,
      "start_date": "2007-08",
      "completion_date": "2008-04",
      "has_results": true,
      "last_update_posted_date": "2016-05-26",
      "last_synced_at": "2026-07-23T05:33:01.884Z",
      "location_count": 20,
      "location_summary": "Fresno, California • Mission Viejo, California • Louisville, Colorado + 17 more",
      "locations": [
        {
          "city": "Fresno",
          "state": "California"
        },
        {
          "city": "Mission Viejo",
          "state": "California"
        },
        {
          "city": "Louisville",
          "state": "Colorado"
        },
        {
          "city": "Jacksonville",
          "state": "Florida"
        },
        {
          "city": "Bloomington",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00717249"
    },
    {
      "nct_id": "NCT00804999",
      "title": "Two Phase Clinical Study of the Impact of Contact Lenses and Solutions on Corneal Structure",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Normal Contact Lens Wear"
      ],
      "interventions": [
        {
          "name": "Clear Care",
          "type": "DRUG"
        },
        {
          "name": "ReNu",
          "type": "DRUG"
        },
        {
          "name": "OPTI-FREE",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Christine Sindt",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 51,
      "start_date": "2008-11-01",
      "completion_date": "2009-03-01",
      "has_results": true,
      "last_update_posted_date": "2018-01-23",
      "last_synced_at": "2026-07-23T05:33:01.884Z",
      "location_count": 1,
      "location_summary": "Iowa City, Iowa",
      "locations": [
        {
          "city": "Iowa City",
          "state": "Iowa"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00804999"
    },
    {
      "nct_id": "NCT06009458",
      "title": "Acuity 200™ (Fluoroxyfocon A) Orthokeratology Contact Lens for Overnight Wear",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Myopia"
      ],
      "interventions": [
        {
          "name": "Acuity 200™ (fluoroxyfocon A) Orthokeratology Contact Lens for Overnight Wear",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Acuity Polymers, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "7 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "7 Years and older"
      },
      "enrollment_count": 387,
      "start_date": "2023-10-01",
      "completion_date": "2025-09",
      "has_results": false,
      "last_update_posted_date": "2025-01-14",
      "last_synced_at": "2026-07-23T05:33:01.884Z",
      "location_count": 9,
      "location_summary": "Mission Viejo, California • Oakland, California • San Francisco, California + 6 more",
      "locations": [
        {
          "city": "Mission Viejo",
          "state": "California"
        },
        {
          "city": "Oakland",
          "state": "California"
        },
        {
          "city": "San Francisco",
          "state": "California"
        },
        {
          "city": "Sunnyvale",
          "state": "California"
        },
        {
          "city": "Ocoee",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06009458"
    },
    {
      "nct_id": "NCT04789382",
      "title": "Three Daily Wear Monthly Replacement Silicone Hydrogel Contact Lenses With Two Multi-purpose Disinfecting Solution Combinations",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Refractive Errors"
      ],
      "interventions": [
        {
          "name": "LID018869+RepleniSH",
          "type": "DEVICE"
        },
        {
          "name": "LID018869+Biotrue",
          "type": "DEVICE"
        },
        {
          "name": "Biofinity+RepleniSH",
          "type": "DEVICE"
        },
        {
          "name": "PV+Biotrue",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Alcon Research",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 36,
      "start_date": "2021-04-07",
      "completion_date": "2021-05-07",
      "has_results": true,
      "last_update_posted_date": "2022-05-25",
      "last_synced_at": "2026-07-23T05:33:01.884Z",
      "location_count": 1,
      "location_summary": "Maitland, Florida",
      "locations": [
        {
          "city": "Maitland",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04789382"
    }
  ]
}