{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Cornea%3B+Ectasia&page=2",
    "query": {
      "condition": "Cornea; Ectasia",
      "page": 2
    },
    "page_size": 10
  },
  "pagination": {
    "page": 2,
    "page_size": 10,
    "total_count": 10,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Cornea%3B+Ectasia&page=1&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-07-23T20:17:29.300Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT03030755",
      "title": "Corneal Elastography and Patient Specific Modeling",
      "overall_status": "RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Cornea; Ectasia",
        "Refractive Errors",
        "Keratoconus"
      ],
      "interventions": [
        {
          "name": "Optical coherence tomography",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "The Cleveland Clinic",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "16 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "16 Years to 80 Years"
      },
      "enrollment_count": 60,
      "start_date": "2016-05",
      "completion_date": "2027-05",
      "has_results": false,
      "last_update_posted_date": "2026-06-03",
      "last_synced_at": "2026-07-23T20:17:29.300Z",
      "location_count": 1,
      "location_summary": "Cleveland, Ohio",
      "locations": [
        {
          "city": "Cleveland",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03030755"
    },
    {
      "nct_id": "NCT03918408",
      "title": "Safety and Effectiveness of the PXL-Platinum 330 System for Corneal Cross-Linking",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Keratoconus, Unstable",
        "Bacterial Keratitis",
        "Ectasia of Cornea"
      ],
      "interventions": [
        {
          "name": "PXL-330 Platinum device for crosslinking with Peschke ribofflavin solution",
          "type": "COMBINATION_PRODUCT"
        }
      ],
      "intervention_types": [
        "COMBINATION_PRODUCT"
      ],
      "sponsor": "Pacific Clear Vision Institute",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "12 Years",
        "maximum_age": "45 Years",
        "sex": "ALL",
        "summary": "12 Years to 45 Years"
      },
      "enrollment_count": 300,
      "start_date": "2019-09-01",
      "completion_date": "2030-12",
      "has_results": false,
      "last_update_posted_date": "2024-11-12",
      "last_synced_at": "2026-07-23T20:17:29.300Z",
      "location_count": 1,
      "location_summary": "Eugene, Oregon",
      "locations": [
        {
          "city": "Eugene",
          "state": "Oregon"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03918408"
    },
    {
      "nct_id": "NCT01189864",
      "title": "Cross-linking of Corneal Collagen (CXL) With Ultraviolet-A in Asymmetric Corneas",
      "overall_status": "TERMINATED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Keratoconus",
        "Ectasia",
        "Degeneration"
      ],
      "interventions": [
        {
          "name": "Ciprofloxicin or Vigamox or other.",
          "type": "DRUG"
        },
        {
          "name": "Nonsteroidal (Acular, Acuvail, Voltaren Xibrom, etc)",
          "type": "DRUG"
        },
        {
          "name": "Steroid (FML, Pred Forte, Flarex, etc.)",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Cxlusa",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "12 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "12 Years and older"
      },
      "enrollment_count": 3493,
      "start_date": "2010-02-01",
      "completion_date": "2017-02-03",
      "has_results": false,
      "last_update_posted_date": "2018-10-12",
      "last_synced_at": "2026-07-23T20:17:29.300Z",
      "location_count": 16,
      "location_summary": "Scottsdale, Arizona • Laguna Hills, California • San Diego, California + 13 more",
      "locations": [
        {
          "city": "Scottsdale",
          "state": "Arizona"
        },
        {
          "city": "Laguna Hills",
          "state": "California"
        },
        {
          "city": "San Diego",
          "state": "California"
        },
        {
          "city": "San Francisco",
          "state": "California"
        },
        {
          "city": "West Hills",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01189864"
    },
    {
      "nct_id": "NCT04094090",
      "title": "Safety and Effectiveness of the PXL-Platinum 330 System for Corneal Cross-Linking in Eyes With Corneal Ectasia",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Keratoconus",
        "Pellucid Marginal Corneal Degeneration",
        "Corneal Ectasia"
      ],
      "interventions": [
        {
          "name": "PXL-330 Platinum device for crosslinking with Peschke riboflavin solution",
          "type": "COMBINATION_PRODUCT"
        }
      ],
      "intervention_types": [
        "COMBINATION_PRODUCT"
      ],
      "sponsor": "Goodman Eye Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "10 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "10 Years and older"
      },
      "enrollment_count": 500,
      "start_date": "2019-10-19",
      "completion_date": "2029-10-19",
      "has_results": false,
      "last_update_posted_date": "2025-10-20",
      "last_synced_at": "2026-07-23T20:17:29.300Z",
      "location_count": 1,
      "location_summary": "San Francisco, California",
      "locations": [
        {
          "city": "San Francisco",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04094090"
    },
    {
      "nct_id": "NCT04401865",
      "title": "Safety and Effectiveness of the PXL-Platinum 330 System",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1",
        "PHASE2"
      ],
      "conditions": [
        "Corneal Ectasia",
        "Keratoconus",
        "Pellucid Marginal Corneal Degeneration"
      ],
      "interventions": [
        {
          "name": "PXL-330 Platinum device for crosslinking with Peschke riboflavin solution",
          "type": "COMBINATION_PRODUCT"
        }
      ],
      "intervention_types": [
        "COMBINATION_PRODUCT"
      ],
      "sponsor": "Colorado Eye Consultants/Cornea Consultants of Colorado",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "8 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "8 Years and older"
      },
      "enrollment_count": 300,
      "start_date": "2020-06-01",
      "completion_date": "2023-06-30",
      "has_results": false,
      "last_update_posted_date": "2022-01-25",
      "last_synced_at": "2026-07-23T20:17:29.300Z",
      "location_count": 3,
      "location_summary": "Littleton, Colorado • Highland Park, Illinois • Brecksville, Ohio",
      "locations": [
        {
          "city": "Littleton",
          "state": "Colorado"
        },
        {
          "city": "Highland Park",
          "state": "Illinois"
        },
        {
          "city": "Brecksville",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04401865"
    },
    {
      "nct_id": "NCT00679666",
      "title": "Corneal Crosslinking in Keratoconus and Corneal Ectasia",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2",
        "PHASE3"
      ],
      "conditions": [
        "Progressive Keratoconus",
        "Corneal Ectasia"
      ],
      "interventions": [
        {
          "name": "Riboflavin",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Ohio State University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 0,
      "start_date": "2008-04",
      "completion_date": "2010-10",
      "has_results": false,
      "last_update_posted_date": "2017-04-20",
      "last_synced_at": "2026-07-23T20:17:29.300Z",
      "location_count": 2,
      "location_summary": "Columbus, Ohio • Dublin, Ohio",
      "locations": [
        {
          "city": "Columbus",
          "state": "Ohio"
        },
        {
          "city": "Dublin",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00679666"
    },
    {
      "nct_id": "NCT01464268",
      "title": "Transepithelial Corneal Collagen Crosslinking for Keratoconus and Corneal Ectasia",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Keratoconus",
        "Corneal Ectasia"
      ],
      "interventions": [
        {
          "name": "Riboflavin",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Cornea and Laser Eye Institute",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 160,
      "start_date": "2011-11",
      "completion_date": "2025-12",
      "has_results": false,
      "last_update_posted_date": "2023-02-08",
      "last_synced_at": "2026-07-23T20:17:29.300Z",
      "location_count": 1,
      "location_summary": "Teaneck, New Jersey",
      "locations": [
        {
          "city": "Teaneck",
          "state": "New Jersey"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01464268"
    },
    {
      "nct_id": "NCT04240457",
      "title": "Safety and Efficacy of Corneal Crosslinking Using the PXL-Platinum 330 for Eyes With Corneal Ectatic Conditions",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Keratoconus",
        "Cornea Ectasia"
      ],
      "interventions": [
        {
          "name": "Epithelial-on Corneal Crosslinking with the PXL 330 Platinum system.",
          "type": "COMBINATION_PRODUCT"
        }
      ],
      "intervention_types": [
        "COMBINATION_PRODUCT"
      ],
      "sponsor": "Arbor Center for Eye Care",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "12 Years",
        "maximum_age": "60 Years",
        "sex": "ALL",
        "summary": "12 Years to 60 Years"
      },
      "enrollment_count": 11,
      "start_date": "2020-07-08",
      "completion_date": "2023-02-18",
      "has_results": true,
      "last_update_posted_date": "2024-12-12",
      "last_synced_at": "2026-07-23T20:17:29.300Z",
      "location_count": 1,
      "location_summary": "Orland Park, Illinois",
      "locations": [
        {
          "city": "Orland Park",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04240457"
    },
    {
      "nct_id": "NCT04698590",
      "title": "Wavefront Guided Scleral Lenses for Keratoconus and Irregular Astigmatism",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Keratoconus",
        "Irregular Astigmatism",
        "Corneal Ectasia",
        "Aberration, Corneal Wavefront",
        "Wavefront Aberration, Corneal",
        "Pellucid Marginal Corneal Degeneration",
        "Keratoglobus"
      ],
      "interventions": [
        {
          "name": "Wavefront Guided Scleral Lenses",
          "type": "DEVICE"
        },
        {
          "name": "Traditional Scleral Lenses",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Cornea and Laser Eye Institute",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 100,
      "start_date": "2021-01-15",
      "completion_date": "2025-12-31",
      "has_results": false,
      "last_update_posted_date": "2024-05-03",
      "last_synced_at": "2026-07-23T20:17:29.300Z",
      "location_count": 1,
      "location_summary": "Teaneck, New Jersey",
      "locations": [
        {
          "city": "Teaneck",
          "state": "New Jersey"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04698590"
    },
    {
      "nct_id": "NCT01956474",
      "title": "CXL-04 A Study of Collagen Crosslinking With Ultraviolet-A in Asymmetric Corneas",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Keratoconus"
      ],
      "interventions": [
        {
          "name": "Theralight crosslinking and Riboflavin",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Cxlusa",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "8 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "8 Years and older"
      },
      "enrollment_count": 1324,
      "start_date": "2013-01",
      "completion_date": "2017-02-03",
      "has_results": false,
      "last_update_posted_date": "2018-10-12",
      "last_synced_at": "2026-07-23T20:17:29.300Z",
      "location_count": 6,
      "location_summary": "Miami, Florida • Atlanta, Georgia • Rockville, Maryland + 3 more",
      "locations": [
        {
          "city": "Miami",
          "state": "Florida"
        },
        {
          "city": "Atlanta",
          "state": "Georgia"
        },
        {
          "city": "Rockville",
          "state": "Maryland"
        },
        {
          "city": "Boston",
          "state": "Massachusetts"
        },
        {
          "city": "Brecksville",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01956474"
    }
  ]
}