{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Corneal+Dystrophies%2C+Hereditary&page=2",
    "query": {
      "condition": "Corneal Dystrophies, Hereditary",
      "page": 2
    },
    "page_size": 10
  },
  "pagination": {
    "page": 2,
    "page_size": 10,
    "total_count": 10,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Corneal+Dystrophies%2C+Hereditary&page=1&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-07-23T14:09:13.074Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT04676737",
      "title": "TTHX1114(NM141) in Combination With DWEK/DSO",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Fuchs' Endothelial Dystrophy",
        "Fuchs Dystrophy",
        "Fuchs"
      ],
      "interventions": [
        {
          "name": "TTHX1114(NM141)",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Trefoil Therapeutics, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 49,
      "start_date": "2021-02-01",
      "completion_date": "2023-01-13",
      "has_results": false,
      "last_update_posted_date": "2023-11-07",
      "last_synced_at": "2026-07-23T14:09:13.074Z",
      "location_count": 11,
      "location_summary": "Long Beach, California • Petaluma, California • Deerfield Beach, Florida + 8 more",
      "locations": [
        {
          "city": "Long Beach",
          "state": "California"
        },
        {
          "city": "Petaluma",
          "state": "California"
        },
        {
          "city": "Deerfield Beach",
          "state": "Florida"
        },
        {
          "city": "Fort Myers",
          "state": "Florida"
        },
        {
          "city": "Indianapolis",
          "state": "Indiana"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04676737"
    },
    {
      "nct_id": "NCT04057053",
      "title": "Netarsudil Use After Descemetorhexis Without Endothelial Keratoplasty",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "EARLY_PHASE1"
      ],
      "conditions": [
        "Fuchs' Endothelial Dystrophy",
        "Cataract"
      ],
      "interventions": [
        {
          "name": "Netarsudil 0.02% Ophthalmic Solution",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Massachusetts Eye and Ear Infirmary",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "50 Years",
        "maximum_age": "70 Years",
        "sex": "ALL",
        "summary": "50 Years to 70 Years"
      },
      "enrollment_count": 10,
      "start_date": "2018-10-02",
      "completion_date": "2020-12-20",
      "has_results": false,
      "last_update_posted_date": "2021-01-26",
      "last_synced_at": "2026-07-23T14:09:13.074Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04057053"
    },
    {
      "nct_id": "NCT04051463",
      "title": "Rhopressa for Corneal Edema Associated With Fuchs Dystrophy",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2",
        "PHASE3"
      ],
      "conditions": [
        "Fuchs Endothelial Dystrophy"
      ],
      "interventions": [
        {
          "name": "Netarsudil Ophthalmic Solution",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Price Vision Group",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 29,
      "start_date": "2019-08-05",
      "completion_date": "2020-07-01",
      "has_results": true,
      "last_update_posted_date": "2021-10-19",
      "last_synced_at": "2026-07-23T14:09:13.074Z",
      "location_count": 1,
      "location_summary": "Indianapolis, Indiana",
      "locations": [
        {
          "city": "Indianapolis",
          "state": "Indiana"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04051463"
    },
    {
      "nct_id": "NCT05826353",
      "title": "A Study to Investigate the Safety and Efficacy of K-321 Eye Drops After Simultaneous Cataract Surgery and Descemetorhexis in Participants With Fuchs Endothelial Corneal Dystrophy (FECD)",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Fuchs Endothelial Corneal Dystrophy"
      ],
      "interventions": [
        {
          "name": "Ripasudil",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Kowa Research Institute, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 110,
      "start_date": "2023-05-11",
      "completion_date": "2025-10-24",
      "has_results": false,
      "last_update_posted_date": "2026-01-22",
      "last_synced_at": "2026-07-23T14:09:13.074Z",
      "location_count": 21,
      "location_summary": "Los Angeles, California • Palo Alto, California • Sacramento, California + 17 more",
      "locations": [
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Palo Alto",
          "state": "California"
        },
        {
          "city": "Sacramento",
          "state": "California"
        },
        {
          "city": "Fort Myers",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05826353"
    },
    {
      "nct_id": "NCT05275972",
      "title": "Descemet Endothelial Thickness Comparison Trial II",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Fuchs",
        "Fuchs Dystrophy",
        "Fuchs' Endothelial Dystrophy"
      ],
      "interventions": [
        {
          "name": "Ripasudil",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Stanford University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 60,
      "start_date": "2023-01-23",
      "completion_date": "2028-11-30",
      "has_results": false,
      "last_update_posted_date": "2026-05-08",
      "last_synced_at": "2026-07-23T14:09:13.074Z",
      "location_count": 8,
      "location_summary": "Palo Alto, California • Sacramento, California • Palm Beach Gardens, Florida + 3 more",
      "locations": [
        {
          "city": "Palo Alto",
          "state": "California"
        },
        {
          "city": "Sacramento",
          "state": "California"
        },
        {
          "city": "Palm Beach Gardens",
          "state": "Florida"
        },
        {
          "city": "Lebanon",
          "state": "New Hampshire"
        },
        {
          "city": "Portland",
          "state": "Oregon"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05275972"
    },
    {
      "nct_id": "NCT04894110",
      "title": "Study of Safety and Tolerability of EO2002 in the Treatment of Corneal Edema",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Corneal Edema",
        "Corneal Endothelial Dysfunction",
        "Corneal Endothelial Dystrophy",
        "Fuchs Dystrophy",
        "Fuchs Endothelial Corneal Dystrophy",
        "Pseudophakic Bullous Keratopathy",
        "Bullous Keratopathy",
        "Endothelial Dysfunction",
        "Moderate Corneal Endothelial Decompensation"
      ],
      "interventions": [
        {
          "name": "EO2002",
          "type": "BIOLOGICAL"
        },
        {
          "name": "EO2002 low dose",
          "type": "BIOLOGICAL"
        },
        {
          "name": "EO2002 mid dose",
          "type": "BIOLOGICAL"
        },
        {
          "name": "EO2002 high dose",
          "type": "BIOLOGICAL"
        }
      ],
      "intervention_types": [
        "BIOLOGICAL"
      ],
      "sponsor": "Emmecell",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "21 Years and older"
      },
      "enrollment_count": 42,
      "start_date": "2021-06-22",
      "completion_date": "2024-10-03",
      "has_results": false,
      "last_update_posted_date": "2025-03-05",
      "last_synced_at": "2026-07-23T14:09:13.074Z",
      "location_count": 8,
      "location_summary": "Greater Los Angeles, California • San Diego, California • Miami, Florida + 5 more",
      "locations": [
        {
          "city": "Greater Los Angeles",
          "state": "California"
        },
        {
          "city": "San Diego",
          "state": "California"
        },
        {
          "city": "Miami",
          "state": "Florida"
        },
        {
          "city": "Palm Beach Gardens",
          "state": "Florida"
        },
        {
          "city": "Atlanta",
          "state": "Georgia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04894110"
    },
    {
      "nct_id": "NCT01067742",
      "title": "The Natural History of Mucolipidosis Type IV",
      "overall_status": "TERMINATED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Mucolipidosis Type IV"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Baylor Research Institute",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "1 Year",
        "maximum_age": "64 Years",
        "sex": "ALL",
        "summary": "1 Year to 64 Years"
      },
      "enrollment_count": 7,
      "start_date": "2009-02-19",
      "completion_date": "2021-07-07",
      "has_results": false,
      "last_update_posted_date": "2026-01-26",
      "last_synced_at": "2026-07-23T14:09:13.074Z",
      "location_count": 1,
      "location_summary": "Dallas, Texas",
      "locations": [
        {
          "city": "Dallas",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01067742"
    },
    {
      "nct_id": "NCT00624221",
      "title": "Study of Eye Bank Pre-cut Donor Grafts for Endothelial Keratoplasty",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Fuchs Endothelial Dystrophy",
        "Corneal Edema"
      ],
      "interventions": [
        {
          "name": "Descemet's stripping endothelial keratoplasty",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Cornea Research Foundation of America",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "21 Years and older"
      },
      "enrollment_count": 40,
      "start_date": "2006-01",
      "completion_date": "2007-11",
      "has_results": true,
      "last_update_posted_date": "2016-04-27",
      "last_synced_at": "2026-07-23T14:09:13.074Z",
      "location_count": 1,
      "location_summary": "Indianapolis, Indiana",
      "locations": [
        {
          "city": "Indianapolis",
          "state": "Indiana"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00624221"
    },
    {
      "nct_id": "NCT00346853",
      "title": "Phase 1 Pilot Study of 4-MP to Treat Stargardt Macular Dystrophy",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Macular Dystrophy, Corneal"
      ],
      "interventions": [
        {
          "name": "4-Methylpyrazole",
          "type": "DRUG"
        },
        {
          "name": "saline",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DRUG",
        "OTHER"
      ],
      "sponsor": "University of Utah",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 10,
      "start_date": "2005-11",
      "completion_date": "2006-09",
      "has_results": false,
      "last_update_posted_date": "2020-08-05",
      "last_synced_at": "2026-07-23T14:09:13.074Z",
      "location_count": 1,
      "location_summary": "Salt Lake City, Utah",
      "locations": [
        {
          "city": "Salt Lake City",
          "state": "Utah"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00346853"
    },
    {
      "nct_id": "NCT01361282",
      "title": "Using the Optovue OCT to Select IOL Power",
      "overall_status": "TERMINATED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Fuchs' Endothelial Dystrophy",
        "Cataract"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Legacy Health System",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 50,
      "start_date": "2010-11-09",
      "completion_date": "2016-09-09",
      "has_results": false,
      "last_update_posted_date": "2017-03-13",
      "last_synced_at": "2026-07-23T14:09:13.074Z",
      "location_count": 1,
      "location_summary": "Portland, Oregon",
      "locations": [
        {
          "city": "Portland",
          "state": "Oregon"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01361282"
    }
  ]
}