{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Corneal+Dystrophy&page=2",
    "query": {
      "condition": "Corneal Dystrophy",
      "page": 2
    },
    "page_size": 10
  },
  "pagination": {
    "page": 2,
    "page_size": 10,
    "total_count": 10,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Corneal+Dystrophy&page=1&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-05-22T06:47:31.886Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT04812067",
      "title": "A Safety and Efficacy Trial of TTHX1114 in People With CED",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Corneal Endothelial Dystrophy"
      ],
      "interventions": [
        {
          "name": "TTHX1114",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Trefoil Therapeutics, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 41,
      "start_date": "2021-11-30",
      "completion_date": "2023-10-31",
      "has_results": false,
      "last_update_posted_date": "2023-11-07",
      "last_synced_at": "2026-05-22T06:47:31.886Z",
      "location_count": 2,
      "location_summary": "Atlanta, Georgia • Washington, Missouri",
      "locations": [
        {
          "city": "Atlanta",
          "state": "Georgia"
        },
        {
          "city": "Washington",
          "state": "Missouri"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04812067"
    },
    {
      "nct_id": "NCT04527523",
      "title": "Descemet Membrane Endothelial Keratoplasty vs. Descemet's Stripping With Endothelial Keratoplasty vs. Descemet Stripping Only",
      "overall_status": "TERMINATED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Cystoid Macular Edema",
        "Fuchs Dystrophy"
      ],
      "interventions": [
        {
          "name": "Optical Coherence Tomography",
          "type": "DIAGNOSTIC_TEST"
        }
      ],
      "intervention_types": [
        "DIAGNOSTIC_TEST"
      ],
      "sponsor": "Wake Forest University Health Sciences",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 4,
      "start_date": "2020-11-21",
      "completion_date": "2022-08-24",
      "has_results": false,
      "last_update_posted_date": "2023-01-13",
      "last_synced_at": "2026-05-22T06:47:31.886Z",
      "location_count": 1,
      "location_summary": "Winston-Salem, North Carolina",
      "locations": [
        {
          "city": "Winston-Salem",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04527523"
    },
    {
      "nct_id": "NCT04051463",
      "title": "Rhopressa for Corneal Edema Associated With Fuchs Dystrophy",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2",
        "PHASE3"
      ],
      "conditions": [
        "Fuchs Endothelial Dystrophy"
      ],
      "interventions": [
        {
          "name": "Netarsudil Ophthalmic Solution",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Price Vision Group",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 29,
      "start_date": "2019-08-05",
      "completion_date": "2020-07-01",
      "has_results": true,
      "last_update_posted_date": "2021-10-19",
      "last_synced_at": "2026-05-22T06:47:31.886Z",
      "location_count": 1,
      "location_summary": "Indianapolis, Indiana",
      "locations": [
        {
          "city": "Indianapolis",
          "state": "Indiana"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04051463"
    },
    {
      "nct_id": "NCT00343473",
      "title": "Novel Diagnostics With Optical Coherence Tomography: Imaging the Anterior Eye",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Fuch's Dystrophy",
        "Corneal Disorders",
        "Prior Surgery"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "NYU Langone Health",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "90 Years",
        "sex": "ALL",
        "summary": "18 Years to 90 Years"
      },
      "enrollment_count": 22,
      "start_date": "2005-10",
      "completion_date": "2024-02-14",
      "has_results": false,
      "last_update_posted_date": "2024-07-01",
      "last_synced_at": "2026-05-22T06:47:31.886Z",
      "location_count": 2,
      "location_summary": "New York, New York • Pittsburgh, Pennsylvania",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        },
        {
          "city": "Pittsburgh",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00343473"
    },
    {
      "nct_id": "NCT05134480",
      "title": "Impact of Donor Diabetes on DMEK Success and Endothelial Cell Loss",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Corneal Endothelial Decompensation",
        "Fuchs' Endothelial Dystrophy"
      ],
      "interventions": [
        {
          "name": "Descemet membrane endothelial keratoplasty",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Case Western Reserve University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "30 Years",
        "maximum_age": "90 Years",
        "sex": "ALL",
        "summary": "30 Years to 90 Years"
      },
      "enrollment_count": 1097,
      "start_date": "2022-01-21",
      "completion_date": "2025-09-15",
      "has_results": true,
      "last_update_posted_date": "2026-04-16",
      "last_synced_at": "2026-05-22T06:47:31.886Z",
      "location_count": 2,
      "location_summary": "Indianapolis, Indiana • Grand Rapids, Michigan",
      "locations": [
        {
          "city": "Indianapolis",
          "state": "Indiana"
        },
        {
          "city": "Grand Rapids",
          "state": "Michigan"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05134480"
    },
    {
      "nct_id": "NCT04440280",
      "title": "Targeting Reactive Oxygen Species Production as a Novel Therapeutic in Fuch's Endothelial Corneal Dystrophy",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Fuchs Endothelial Corneal Dystrophy"
      ],
      "interventions": [
        {
          "name": "N-acetyl cysteine (NAC) 10% solution",
          "type": "DRUG"
        },
        {
          "name": "N-acetyl cysteine (NAC) 20% solution",
          "type": "DRUG"
        },
        {
          "name": "Visine Dry Eye Relief eye drops",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Massachusetts Eye and Ear Infirmary",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "21 Years and older"
      },
      "enrollment_count": 45,
      "start_date": "2020-09-16",
      "completion_date": "2027-04-30",
      "has_results": false,
      "last_update_posted_date": "2025-09-29",
      "last_synced_at": "2026-05-22T06:47:31.886Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04440280"
    },
    {
      "nct_id": "NCT04018417",
      "title": "Evaluation of Amphotericin B in Optisol-GS for Prevention of Post-Keratoplasty Fungal Infections.",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2",
        "PHASE3"
      ],
      "conditions": [
        "Fuchs' Endothelial Dystrophy"
      ],
      "interventions": [
        {
          "name": "Amphotericin B",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Cornea Research Foundation of America",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 0,
      "start_date": "2019-07-03",
      "completion_date": "2019-07-03",
      "has_results": false,
      "last_update_posted_date": "2019-07-12",
      "last_synced_at": "2026-05-22T06:47:31.886Z",
      "location_count": 1,
      "location_summary": "Indianapolis, Indiana",
      "locations": [
        {
          "city": "Indianapolis",
          "state": "Indiana"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04018417"
    },
    {
      "nct_id": "NCT02871050",
      "title": "Castleman Disease Collaborative Network Biobank",
      "overall_status": "WITHDRAWN",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Castleman Disease",
        "Castleman's Disease",
        "Giant Lymph Node Hyperplasia",
        "Angiofollicular Lymph Hyperplasia",
        "Angiofollicular Lymph Node Hyperplasia",
        "Angiofollicular Lymphoid Hyperplasia",
        "GLNH",
        "Hyperplasia",
        "Giant Lymph Node"
      ],
      "interventions": [
        {
          "name": "Sample Collection",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Castleman Disease Collaborative Network",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 0,
      "start_date": "2016-06",
      "completion_date": "2018-06",
      "has_results": false,
      "last_update_posted_date": "2018-07-31",
      "last_synced_at": "2026-05-22T06:47:31.886Z",
      "location_count": 1,
      "location_summary": "Philadelphia, Pennsylvania",
      "locations": [
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02871050"
    },
    {
      "nct_id": "NCT04250207",
      "title": "Study to Investigate the Safety and Efficacy of K-321 in Patients With Fuchs Endothelial Corneal Dystrophy (FECD) Following Descemetorhexis",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Fuchs' Endothelial Corneal Dystrophy"
      ],
      "interventions": [
        {
          "name": "K-321 Solution",
          "type": "DRUG"
        },
        {
          "name": "Placebo Solution",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Kowa Research Institute, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 65,
      "start_date": "2020-06-23",
      "completion_date": "2022-06-27",
      "has_results": true,
      "last_update_posted_date": "2024-11-05",
      "last_synced_at": "2026-05-22T06:47:31.886Z",
      "location_count": 19,
      "location_summary": "Los Angeles, California • Palo Alto, California • Sacramento, California + 14 more",
      "locations": [
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Palo Alto",
          "state": "California"
        },
        {
          "city": "Sacramento",
          "state": "California"
        },
        {
          "city": "Sacramento",
          "state": "California"
        },
        {
          "city": "Fort Myers",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04250207"
    },
    {
      "nct_id": "NCT02853968",
      "title": "Unlock the Cell: Castleman's Disease Flow Cytometry Study",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Castleman Disease",
        "Angiofollicular Lymphoid Hyperplasia",
        "GLNH",
        "Hyperplasia",
        "Castleman's Disease",
        "Angiofollicular Lymph Hyperplasia",
        "Giant Lymph Node Hyperplasia"
      ],
      "interventions": [
        {
          "name": "Blood draw/buccal swab",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "University of Pennsylvania",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 130,
      "start_date": "2016-02",
      "completion_date": "2019-03-30",
      "has_results": false,
      "last_update_posted_date": "2020-03-26",
      "last_synced_at": "2026-05-22T06:47:31.886Z",
      "location_count": 1,
      "location_summary": "Philadelphia, Pennsylvania",
      "locations": [
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02853968"
    }
  ]
}