{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Coronary+Artery+Disease+Progression&page=2",
    "query": {
      "condition": "Coronary Artery Disease Progression",
      "page": 2
    },
    "page_size": 10
  },
  "pagination": {
    "page": 2,
    "page_size": 10,
    "total_count": 10,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Coronary+Artery+Disease+Progression&page=1&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-07-23T18:15:56.317Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT01316159",
      "title": "Prediction of Progression of Coronary Artery Disease (CAD) Using Vascular Profiling of Shear Stress and Wall Morphology",
      "overall_status": "UNKNOWN",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Coronary Atherosclerosis",
        "Acute Coronary Syndrome",
        "Percutaneous Coronary Intervention",
        "Endothelial Shear Stress",
        "Arterial Remodeling"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Brigham and Women's Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 506,
      "start_date": "2007-04",
      "completion_date": "2012-12",
      "has_results": false,
      "last_update_posted_date": "2011-03-16",
      "last_synced_at": "2026-07-23T18:15:56.317Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01316159"
    },
    {
      "nct_id": "NCT05867381",
      "title": "Using Indoor Air Filtration to Slow Atherothrombosis Progression in Adults With Ischemic Heart Disease History",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Air Pollution",
        "Atherosclerosis"
      ],
      "interventions": [
        {
          "name": "HEPA filtration",
          "type": "DEVICE"
        },
        {
          "name": "Sham filtration",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "University of Southern California",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "65 Years",
        "maximum_age": "84 Years",
        "sex": "ALL",
        "summary": "65 Years to 84 Years"
      },
      "enrollment_count": 112,
      "start_date": "2023-07-11",
      "completion_date": "2028-06-30",
      "has_results": false,
      "last_update_posted_date": "2026-06-08",
      "last_synced_at": "2026-07-23T18:15:56.317Z",
      "location_count": 1,
      "location_summary": "Los Angeles, California",
      "locations": [
        {
          "city": "Los Angeles",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05867381"
    },
    {
      "nct_id": "NCT00659256",
      "title": "Hepatitis C Treatment and Atherosclerosis",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Chronic Hepatitis C",
        "Atherosclerosis"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)",
      "sponsor_class": "NIH",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "30 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "30 Years and older"
      },
      "enrollment_count": 70,
      "start_date": "2008-04-08",
      "completion_date": "2015-03-24",
      "has_results": false,
      "last_update_posted_date": "2019-12-12",
      "last_synced_at": "2026-07-23T18:15:56.317Z",
      "location_count": 1,
      "location_summary": "Bethesda, Maryland",
      "locations": [
        {
          "city": "Bethesda",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00659256"
    },
    {
      "nct_id": "NCT00154180",
      "title": "Kronos Early Estrogen Prevention Study (KEEPS)",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Menopause",
        "Arteriosclerosis"
      ],
      "interventions": [
        {
          "name": "Conjugated equine estrogens 0.45 mg/day",
          "type": "DRUG"
        },
        {
          "name": "Transdermal estradiol, 50 mcg/day",
          "type": "DRUG"
        },
        {
          "name": "Micronized progesterone, 200 mg/day x 12 d/month",
          "type": "DRUG"
        },
        {
          "name": "CEE , progesterone, estradiol patch or placebo for each",
          "type": "DRUG"
        },
        {
          "name": "CEE, progesterone, transdermal patch or the placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Kronos Longevity Research Institute",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "42 Years",
        "maximum_age": "58 Years",
        "sex": "FEMALE",
        "summary": "42 Years to 58 Years · Female only"
      },
      "enrollment_count": 728,
      "start_date": "2005-09",
      "completion_date": "2012-07",
      "has_results": false,
      "last_update_posted_date": "2009-09-14",
      "last_synced_at": "2026-07-23T18:15:56.317Z",
      "location_count": 9,
      "location_summary": "Phoenix, Arizona • San Francisco, California • New Haven, Connecticut + 6 more",
      "locations": [
        {
          "city": "Phoenix",
          "state": "Arizona"
        },
        {
          "city": "San Francisco",
          "state": "California"
        },
        {
          "city": "New Haven",
          "state": "Connecticut"
        },
        {
          "city": "Boston",
          "state": "Massachusetts"
        },
        {
          "city": "Rochester",
          "state": "Minnesota"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00154180"
    },
    {
      "nct_id": "NCT00297219",
      "title": "Effects of Lowering Dialysate Calcium Level on Progression of Coronary Artery Calcification and Bone Histomorphometry",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "End-Stage Renal Disease",
        "Hemodialysis"
      ],
      "interventions": [
        {
          "name": "Low dialysate calcium",
          "type": "DRUG"
        },
        {
          "name": "high dialysate calcium",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Ege University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "18 Years to 80 Years"
      },
      "enrollment_count": 457,
      "start_date": "2005-11",
      "completion_date": "2008-07",
      "has_results": false,
      "last_update_posted_date": "2009-08-04",
      "last_synced_at": "2026-07-23T18:15:56.317Z",
      "location_count": 1,
      "location_summary": "Lexington, Kentucky",
      "locations": [
        {
          "city": "Lexington",
          "state": "Kentucky"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00297219"
    },
    {
      "nct_id": "NCT00860847",
      "title": "Firefighter Aged Garlic Extract Investigation With CoQ10 as a Treatment for Heart Disease (FAITH)",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Coronary Atherosclerosis",
        "Coronary Artery Calcification",
        "Coronary Stenosis"
      ],
      "interventions": [
        {
          "name": "Aged garlic extract and Coenzyme Q10",
          "type": "DIETARY_SUPPLEMENT"
        }
      ],
      "intervention_types": [
        "DIETARY_SUPPLEMENT"
      ],
      "sponsor": "Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "35 Years",
        "maximum_age": "84 Years",
        "sex": "MALE",
        "summary": "35 Years to 84 Years · Male only"
      },
      "enrollment_count": 65,
      "start_date": "2009-05",
      "completion_date": "2010-09",
      "has_results": true,
      "last_update_posted_date": "2015-03-12",
      "last_synced_at": "2026-07-23T18:15:56.317Z",
      "location_count": 1,
      "location_summary": "Torrance, California",
      "locations": [
        {
          "city": "Torrance",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00860847"
    },
    {
      "nct_id": "NCT05360446",
      "title": "Coronary Computed Tomography Study to Assess the Effect of Inclisiran in Addition to Maximally Tolerated Statin Therapy on Atherosclerotic Plaque Progression in Participants With a Diagnosis of Non-obstructive Coronary Artery Disease Without Previous Cardiovascular Events",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Coronary Artery Disease"
      ],
      "interventions": [
        {
          "name": "Inclisiran sodium 300 mg",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Novartis Pharmaceuticals",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "18 Years to 80 Years"
      },
      "enrollment_count": 609,
      "start_date": "2022-07-08",
      "completion_date": "2026-10-26",
      "has_results": false,
      "last_update_posted_date": "2026-07-13",
      "last_synced_at": "2026-07-23T18:15:56.317Z",
      "location_count": 27,
      "location_summary": "Huntsville, Alabama • Anchorage, Alaska • Beverly Hills, California + 22 more",
      "locations": [
        {
          "city": "Huntsville",
          "state": "Alabama"
        },
        {
          "city": "Anchorage",
          "state": "Alaska"
        },
        {
          "city": "Beverly Hills",
          "state": "California"
        },
        {
          "city": "La Jolla",
          "state": "California"
        },
        {
          "city": "Stanford",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05360446"
    },
    {
      "nct_id": "NCT01059682",
      "title": "A Study of the Effect of Dalcetrapib on Artherosclerotic Disease in Patients With Coronary Artery Disease",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Cardiovascular Disease"
      ],
      "interventions": [
        {
          "name": "Dalcetrapib",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Hoffmann-La Roche",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 936,
      "start_date": "2010-01",
      "completion_date": "2011-09",
      "has_results": true,
      "last_update_posted_date": "2020-03-24",
      "last_synced_at": "2026-07-23T18:15:56.317Z",
      "location_count": 41,
      "location_summary": "Los Angeles, California • Torrance, California • Boulder, Colorado + 36 more",
      "locations": [
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Torrance",
          "state": "California"
        },
        {
          "city": "Boulder",
          "state": "Colorado"
        },
        {
          "city": "Greeley",
          "state": "Colorado"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01059682"
    },
    {
      "nct_id": "NCT02966028",
      "title": "Effect of SNF472 on Progression of Cardiovascular Calcification in End-Stage-Renal-Disease (ESRD) Patients on Hemodialysis (HD)",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Cardiovascular Diseases",
        "Cardiovascular Abnormalities",
        "Calcifications, Vascular",
        "Endstage Renal Disease",
        "ESRD",
        "Coronary Artery Calcification"
      ],
      "interventions": [
        {
          "name": "SNF472",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Sanifit Therapeutics S. A.",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "18 Years to 80 Years"
      },
      "enrollment_count": 274,
      "start_date": "2016-11",
      "completion_date": "2019-09",
      "has_results": true,
      "last_update_posted_date": "2021-04-15",
      "last_synced_at": "2026-07-23T18:15:56.317Z",
      "location_count": 46,
      "location_summary": "Bakersfield, California • Chula Vista, California • Escondido, California + 42 more",
      "locations": [
        {
          "city": "Bakersfield",
          "state": "California"
        },
        {
          "city": "Chula Vista",
          "state": "California"
        },
        {
          "city": "Escondido",
          "state": "California"
        },
        {
          "city": "Granada Hills",
          "state": "California"
        },
        {
          "city": "La Palma",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02966028"
    },
    {
      "nct_id": "NCT00380939",
      "title": "This Study Uses Ultrasound to Determine Whether Atorvastatin or Pravastatin Effects the Progression of Coronary Plaque.",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Coronary Arteriosclerosis"
      ],
      "interventions": [
        {
          "name": "Atorvastatin",
          "type": "DRUG"
        },
        {
          "name": "Pravastatin",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Pfizer",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "30 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "30 Years to 75 Years"
      },
      "enrollment_count": 600,
      "start_date": "1999-04",
      "completion_date": "2000-12",
      "has_results": false,
      "last_update_posted_date": "2006-12-04",
      "last_synced_at": "2026-07-23T18:15:56.317Z",
      "location_count": 36,
      "location_summary": "Little Rock, Arkansas • Los Angeles, California • San Diego, California + 30 more",
      "locations": [
        {
          "city": "Little Rock",
          "state": "Arkansas"
        },
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "San Diego",
          "state": "California"
        },
        {
          "city": "Denver",
          "state": "Colorado"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00380939"
    }
  ]
}