{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Cough+Hypersensitivity",
    "query": {
      "condition": "Cough Hypersensitivity"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 23,
    "total_pages": 3,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Cough+Hypersensitivity&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-07-23T23:04:50.438Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT02062710",
      "title": "Antitussive Effect of a Naturally Flavored Syrup Containing Diphenhydramine, Compared With Dextromethorphan and Placebo",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Cough Reflex Sensitivity"
      ],
      "interventions": [
        {
          "name": "diphenhydramine/phenylephrine/cocoa; dextromethorophan; placebo",
          "type": "DRUG"
        },
        {
          "name": "diphenhydramine/phenylephrine/cocoa; placebo; dextromethorphan",
          "type": "DRUG"
        },
        {
          "name": "dextromethorphan; diphenhydramine/phenylephrine/cocoa; placebo",
          "type": "DRUG"
        },
        {
          "name": "dextromethorophan; placebo; diphenhydramine/phenylephrine/cocoa",
          "type": "DRUG"
        },
        {
          "name": "placebo; diphenhydramine/phenylephrine/cocoa; dextromethorphan",
          "type": "DRUG"
        },
        {
          "name": "placebo; dextromethorphan; diphenhydramine/phenylephrine/cocoa",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Montefiore Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 22,
      "start_date": "2014-01",
      "completion_date": "2014-06",
      "has_results": true,
      "last_update_posted_date": "2018-02-28",
      "last_synced_at": "2026-07-23T23:04:50.438Z",
      "location_count": 1,
      "location_summary": "The Bronx, New York",
      "locations": [
        {
          "city": "The Bronx",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02062710"
    },
    {
      "nct_id": "NCT02973282",
      "title": "Diagnosing Respiratory Disease in Children Using Cough Sounds",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Pneumonia",
        "Bronchiolitis",
        "Asthma",
        "Croup",
        "Upper Respiratory Tract Infection",
        "Lower Respiratory Tract Infection",
        "Reactive Airway Disease"
      ],
      "interventions": [
        {
          "name": "Recording of Infants and Children's Cough Sounds",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "ResApp Health Limited",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "29 Days",
        "maximum_age": "12 Years",
        "sex": "ALL",
        "summary": "29 Days to 12 Years"
      },
      "enrollment_count": 1245,
      "start_date": "2016-12",
      "completion_date": "2017-12",
      "has_results": false,
      "last_update_posted_date": "2018-01-05",
      "last_synced_at": "2026-07-23T23:04:50.438Z",
      "location_count": 3,
      "location_summary": "Boston, Massachusetts • Cleveland, Ohio • Houston, Texas",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        },
        {
          "city": "Cleveland",
          "state": "Ohio"
        },
        {
          "city": "Houston",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02973282"
    },
    {
      "nct_id": "NCT07070895",
      "title": "Cough Management Wellness App for Refractory or Unexplained Chronic Cough",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Refractory Chronic Cough",
        "Unexplained Chronic Cough",
        "Cough Hypersensitivity"
      ],
      "interventions": [
        {
          "name": "Cough Management",
          "type": "BEHAVIORAL"
        },
        {
          "name": "CoughMonitor Suite",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL",
        "DEVICE"
      ],
      "sponsor": "Hyfe Inc",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "21 Years and older"
      },
      "enrollment_count": 20,
      "start_date": "2025-03-27",
      "completion_date": "2025-09",
      "has_results": false,
      "last_update_posted_date": "2025-09-11",
      "last_synced_at": "2026-07-23T23:04:50.438Z",
      "location_count": 1,
      "location_summary": "Wilmington, Delaware",
      "locations": [
        {
          "city": "Wilmington",
          "state": "Delaware"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07070895"
    },
    {
      "nct_id": "NCT01728038",
      "title": "Exploring a Cessation Intervention for Smokers",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Asthma"
      ],
      "interventions": [
        {
          "name": "Cessation Counseling",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Children's Hospital Medical Center, Cincinnati",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 230,
      "start_date": "2012-03",
      "completion_date": "2016-03",
      "has_results": false,
      "last_update_posted_date": "2017-08-30",
      "last_synced_at": "2026-07-23T23:04:50.438Z",
      "location_count": 1,
      "location_summary": "Cincinnati, Ohio",
      "locations": [
        {
          "city": "Cincinnati",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01728038"
    },
    {
      "nct_id": "NCT00588627",
      "title": "Capsaicin Cough Threshold in Chronic Cough Due to Postnasal Drip",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Post Nasal Drip"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Mayo Clinic",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 25,
      "start_date": "2006-03",
      "completion_date": "2008-12",
      "has_results": false,
      "last_update_posted_date": "2010-03-10",
      "last_synced_at": "2026-07-23T23:04:50.438Z",
      "location_count": 1,
      "location_summary": "Rochester, Minnesota",
      "locations": [
        {
          "city": "Rochester",
          "state": "Minnesota"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00588627"
    },
    {
      "nct_id": "NCT07531901",
      "title": "Evaluating the Feasibility and Reliability of Using Handheld Nebulizers to Conduct Cough Sensitivity Testing With Citric Acid",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Cough Reflex Sensitivity"
      ],
      "interventions": [
        {
          "name": "Cosmed QuarkSpiro Dosimeter-Controlled Nebulizer",
          "type": "DEVICE"
        },
        {
          "name": "DeVilbiss 45 Handheld Nebulizer",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "University of Montana",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "89 Years",
        "sex": "ALL",
        "summary": "18 Years to 89 Years"
      },
      "enrollment_count": 10,
      "start_date": "2026-07-15",
      "completion_date": "2027-02-28",
      "has_results": false,
      "last_update_posted_date": "2026-07-20",
      "last_synced_at": "2026-07-23T23:04:50.438Z",
      "location_count": 1,
      "location_summary": "Missoula, Montana",
      "locations": [
        {
          "city": "Missoula",
          "state": "Montana"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07531901"
    },
    {
      "nct_id": "NCT01777867",
      "title": "Cough Reflex Sensitivity and Bronchial Hyper-responsiveness",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Gastroesophageal Reflux Disease",
        "Chronic Cough",
        "Broncho-hyperreactivity"
      ],
      "interventions": [
        {
          "name": "Cough Reflex Sensitivity",
          "type": "PROCEDURE"
        },
        {
          "name": "Methacholine Challenge",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Mayo Clinic",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "60 Years",
        "sex": "ALL",
        "summary": "18 Years to 60 Years"
      },
      "enrollment_count": 24,
      "start_date": "2012-12",
      "completion_date": "2016-02",
      "has_results": false,
      "last_update_posted_date": "2017-02-17",
      "last_synced_at": "2026-07-23T23:04:50.438Z",
      "location_count": 1,
      "location_summary": "Jacksonville, Florida",
      "locations": [
        {
          "city": "Jacksonville",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01777867"
    },
    {
      "nct_id": "NCT02489708",
      "title": "Pediatric Emergency Department Decision Support System to Reduce Secondhand Smoke",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Asthma",
        "Smoking Cessation"
      ],
      "interventions": [
        {
          "name": "Cessation Counseling",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Children's Hospital Medical Center, Cincinnati",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "1 Day",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "1 Day and older"
      },
      "enrollment_count": 150,
      "start_date": "2014-11",
      "completion_date": "2021-12",
      "has_results": false,
      "last_update_posted_date": "2021-12-09",
      "last_synced_at": "2026-07-23T23:04:50.438Z",
      "location_count": 1,
      "location_summary": "Cincinnati, Ohio",
      "locations": [
        {
          "city": "Cincinnati",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02489708"
    },
    {
      "nct_id": "NCT04256733",
      "title": "Cough Desensitization Therapy for Cough Hypersensitivity Syndrome",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "EARLY_PHASE1"
      ],
      "conditions": [
        "Cough"
      ],
      "interventions": [
        {
          "name": "Supra-threshold and progressive doses of diluted capsaicin via a Koko Digidoser nebulizer",
          "type": "BIOLOGICAL"
        },
        {
          "name": "Sub-threshold doses of diluted capsiacin via a KoKo Digidoser nebulizer",
          "type": "BIOLOGICAL"
        }
      ],
      "intervention_types": [
        "BIOLOGICAL"
      ],
      "sponsor": "University of Montana",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "99 Years",
        "sex": "ALL",
        "summary": "18 Years to 99 Years"
      },
      "enrollment_count": 19,
      "start_date": "2019-05-01",
      "completion_date": "2021-02-13",
      "has_results": true,
      "last_update_posted_date": "2024-03-04",
      "last_synced_at": "2026-07-23T23:04:50.438Z",
      "location_count": 1,
      "location_summary": "Missoula, Montana",
      "locations": [
        {
          "city": "Missoula",
          "state": "Montana"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04256733"
    },
    {
      "nct_id": "NCT05110144",
      "title": "Efficacy of Two Doses of Duloxetine and Amitriptyline in Subjects With Refractory Chronic Cough",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Refractory Chronic Cough"
      ],
      "interventions": [
        {
          "name": "Duloxetine 30 MG",
          "type": "DRUG"
        },
        {
          "name": "Duloxetine 60 MG",
          "type": "DRUG"
        },
        {
          "name": "Amitriptyline 25 MG",
          "type": "DRUG"
        },
        {
          "name": "Amitriptyline 50 MG",
          "type": "DRUG"
        },
        {
          "name": "Placebo 30 MG",
          "type": "DRUG"
        },
        {
          "name": "Placebo 60 MG",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Mayo Clinic",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "18 Years to 75 Years"
      },
      "enrollment_count": 50,
      "start_date": "2021-11-01",
      "completion_date": "2026-12",
      "has_results": false,
      "last_update_posted_date": "2026-01-21",
      "last_synced_at": "2026-07-23T23:04:50.438Z",
      "location_count": 1,
      "location_summary": "Rochester, Minnesota",
      "locations": [
        {
          "city": "Rochester",
          "state": "Minnesota"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05110144"
    }
  ]
}