{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Craniofacial+Abnormalities",
    "query": {
      "condition": "Craniofacial Abnormalities"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 177,
    "total_pages": 18,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Craniofacial+Abnormalities&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-06-11T03:00:02.538Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT05917678",
      "title": "Effectiveness of Repositioning and Cranial Remolding in Infants With Cranial Deformation",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Deformational Plagiocephaly",
        "Deformational Posterior Plagiocephaly",
        "Brachycephaly",
        "Torticollis",
        "Congenital Muscular Torticollis"
      ],
      "interventions": [
        {
          "name": "Repositioning Therapy",
          "type": "OTHER"
        },
        {
          "name": "Cranial Remolding Orthosis",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "OTHER",
        "DEVICE"
      ],
      "sponsor": "University of Texas Southwestern Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "2 Months",
        "maximum_age": "3 Months",
        "sex": "ALL",
        "summary": "2 Months to 3 Months"
      },
      "enrollment_count": 65,
      "start_date": "2023-05-23",
      "completion_date": "2026-07-01",
      "has_results": false,
      "last_update_posted_date": "2025-08-28",
      "last_synced_at": "2026-06-11T03:00:02.538Z",
      "location_count": 1,
      "location_summary": "Dallas, Texas",
      "locations": [
        {
          "city": "Dallas",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05917678"
    },
    {
      "nct_id": "NCT07005297",
      "title": "Clinical Genetics Branch Eligibility Screening Survey",
      "overall_status": "NOT_YET_RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Melanoma",
        "Li-Fraumeni Syndrome",
        "Pulmonary Blastoma",
        "Chordoma",
        "Congenital Bone Marrow Failure Syndromes",
        "Costello Syndrome",
        "Fanconi Anemia",
        "CFC Syndrome (CFCS)",
        "Legius Syndrome",
        "RASopathies"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "National Cancer Institute (NCI)",
      "sponsor_class": "NIH",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "1 Year",
        "maximum_age": "99 Years",
        "sex": "ALL",
        "summary": "1 Year to 99 Years"
      },
      "enrollment_count": 1000,
      "start_date": "2026-06-15",
      "completion_date": "2036-01-01",
      "has_results": false,
      "last_update_posted_date": "2026-06-10",
      "last_synced_at": "2026-06-11T03:00:02.538Z",
      "location_count": 1,
      "location_summary": "Rockville, Maryland",
      "locations": [
        {
          "city": "Rockville",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07005297"
    },
    {
      "nct_id": "NCT04035928",
      "title": "Digital Design for Maxillofacial Prosthetics",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Prosthetic Treatment",
        "Craniofacial Abnormalities",
        "Maxillofacial Abnormalities"
      ],
      "interventions": [
        {
          "name": "3D digital scanning for maxillofacial prosthetics",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "University of Michigan",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "6 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "6 Years and older"
      },
      "enrollment_count": 0,
      "start_date": "2019-10-14",
      "completion_date": "2023-07",
      "has_results": false,
      "last_update_posted_date": "2024-06-24",
      "last_synced_at": "2026-06-11T03:00:02.538Z",
      "location_count": 1,
      "location_summary": "Ann Arbor, Michigan",
      "locations": [
        {
          "city": "Ann Arbor",
          "state": "Michigan"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04035928"
    },
    {
      "nct_id": "NCT02846766",
      "title": "Study of Lenvatinib in Patients With Advanced Cancer and Aberrations in FGF/FGFR Signaling",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Cancer"
      ],
      "interventions": [
        {
          "name": "Lenvatinib",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Teresa Helsten, MD",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 0,
      "start_date": "2018-07-01",
      "completion_date": "2021-06-01",
      "has_results": false,
      "last_update_posted_date": "2018-08-02",
      "last_synced_at": "2026-06-11T03:00:02.538Z",
      "location_count": 2,
      "location_summary": "La Jolla, California • Chicago, Illinois",
      "locations": [
        {
          "city": "La Jolla",
          "state": "California"
        },
        {
          "city": "Chicago",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02846766"
    },
    {
      "nct_id": "NCT02229968",
      "title": "Efficacy of Amicar for Children Having Craniofacial Surgery",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Craniosynostosis"
      ],
      "interventions": [
        {
          "name": "Amicar (ε-aminocaproic acid)",
          "type": "DRUG"
        },
        {
          "name": "normal saline",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Children's National Research Institute",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "2 Months",
        "maximum_age": "36 Months",
        "sex": "ALL",
        "summary": "2 Months to 36 Months"
      },
      "enrollment_count": 22,
      "start_date": "2014-10",
      "completion_date": "2028-03",
      "has_results": false,
      "last_update_posted_date": "2026-04-07",
      "last_synced_at": "2026-06-11T03:00:02.538Z",
      "location_count": 1,
      "location_summary": "Nashville, Tennessee",
      "locations": [
        {
          "city": "Nashville",
          "state": "Tennessee"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02229968"
    },
    {
      "nct_id": "NCT06019182",
      "title": "MEHMO Natural History and Biomarkers",
      "overall_status": "RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Intellectual Disability",
        "Epilepsy",
        "Hypogonadisms",
        "Microcephaly",
        "Nervous System Malformations",
        "Obesity"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)",
      "sponsor_class": "NIH",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "1 Week",
        "maximum_age": "100 Years",
        "sex": "ALL",
        "summary": "1 Week to 100 Years"
      },
      "enrollment_count": 150,
      "start_date": "2023-10-23",
      "completion_date": "2053-09-01",
      "has_results": false,
      "last_update_posted_date": "2026-04-27",
      "last_synced_at": "2026-06-11T03:00:02.538Z",
      "location_count": 1,
      "location_summary": "Bethesda, Maryland",
      "locations": [
        {
          "city": "Bethesda",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06019182"
    },
    {
      "nct_id": "NCT03868891",
      "title": "Exercises for Improving Soft Palate and Eustachian Tube Function in Children With Ear Tubes With or Without Cleft Palate",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Cleft Palate",
        "Tube Disorders Eustachian",
        "Velopharyngeal Incompetence Due to Cleft Palate",
        "Velopharyngeal Insufficiency"
      ],
      "interventions": [
        {
          "name": "EMST150",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Noel Jabbour",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "6 Years",
        "maximum_age": "17 Years",
        "sex": "ALL",
        "summary": "6 Years to 17 Years"
      },
      "enrollment_count": 11,
      "start_date": "2019-08-16",
      "completion_date": "2022-05-31",
      "has_results": true,
      "last_update_posted_date": "2023-06-23",
      "last_synced_at": "2026-06-11T03:00:02.538Z",
      "location_count": 1,
      "location_summary": "Pittsburgh, Pennsylvania",
      "locations": [
        {
          "city": "Pittsburgh",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03868891"
    },
    {
      "nct_id": "NCT02747797",
      "title": "Lucitanib (E3810) in Patients With Advanced Cancer and FGFR, VEGFR, or PDGFR Pathway Aberrations",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Advanced Cancer"
      ],
      "interventions": [
        {
          "name": "Lucitanib",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Teresa Helsten, MD",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 0,
      "start_date": "2017-04",
      "completion_date": "2022-04",
      "has_results": false,
      "last_update_posted_date": "2018-08-02",
      "last_synced_at": "2026-06-11T03:00:02.538Z",
      "location_count": 1,
      "location_summary": "La Jolla, California",
      "locations": [
        {
          "city": "La Jolla",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02747797"
    },
    {
      "nct_id": "NCT04252339",
      "title": "RLY-1971 in Subjects With Advanced or Metastatic Solid Tumors",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Solid Tumor, Unspecified, Adult"
      ],
      "interventions": [
        {
          "name": "RLY-1971",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Hoffmann-La Roche",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 56,
      "start_date": "2020-02-04",
      "completion_date": "2022-11-22",
      "has_results": false,
      "last_update_posted_date": "2023-01-31",
      "last_synced_at": "2026-06-11T03:00:02.538Z",
      "location_count": 6,
      "location_summary": "Lake Mary, Florida • Sarasota, Florida • Boston, Massachusetts + 1 more",
      "locations": [
        {
          "city": "Lake Mary",
          "state": "Florida"
        },
        {
          "city": "Sarasota",
          "state": "Florida"
        },
        {
          "city": "Boston",
          "state": "Massachusetts"
        },
        {
          "city": "Boston",
          "state": "Massachusetts"
        },
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04252339"
    },
    {
      "nct_id": "NCT02702869",
      "title": "Allied Cleft & Craniofacial Quality-Improvement and Research Network (ACCQUIREnet)",
      "overall_status": "ENROLLING_BY_INVITATION",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Cleft Lip",
        "Cleft Palate",
        "Cleft Lip and Palate"
      ],
      "interventions": [
        {
          "name": "cleft lip repair",
          "type": "PROCEDURE"
        },
        {
          "name": "cleft palate repair",
          "type": "PROCEDURE"
        },
        {
          "name": "oronasal fistula repair",
          "type": "PROCEDURE"
        },
        {
          "name": "pharyngoplasty",
          "type": "PROCEDURE"
        },
        {
          "name": "gingivoperiosteoplasty",
          "type": "PROCEDURE"
        },
        {
          "name": "LeFort-1 maxillary repositioning",
          "type": "PROCEDURE"
        },
        {
          "name": "rhinoplasty",
          "type": "PROCEDURE"
        },
        {
          "name": "myringotomy and tympanostomy tube placement",
          "type": "PROCEDURE"
        },
        {
          "name": "speech therapy",
          "type": "OTHER"
        },
        {
          "name": "orthodontia",
          "type": "PROCEDURE"
        },
        {
          "name": "presurgical orthopedics",
          "type": "PROCEDURE"
        },
        {
          "name": "sound amplification for hearing",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "PROCEDURE",
        "OTHER",
        "DEVICE"
      ],
      "sponsor": "Duke University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "1 Day",
        "maximum_age": "22 Years",
        "sex": "ALL",
        "summary": "1 Day to 22 Years"
      },
      "enrollment_count": 1000,
      "start_date": "2016-10",
      "completion_date": "2031-12",
      "has_results": false,
      "last_update_posted_date": "2026-01-07",
      "last_synced_at": "2026-06-11T03:00:02.538Z",
      "location_count": 10,
      "location_summary": "Gainesville, Florida • Hollywood, Florida • Orlando, Florida + 7 more",
      "locations": [
        {
          "city": "Gainesville",
          "state": "Florida"
        },
        {
          "city": "Hollywood",
          "state": "Florida"
        },
        {
          "city": "Orlando",
          "state": "Florida"
        },
        {
          "city": "St. Petersburg",
          "state": "Florida"
        },
        {
          "city": "Portland",
          "state": "Maine"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02702869"
    }
  ]
}